IMP

Process View

Rattus norvegicus

11 genes annotated in rat

Multi-species View

negative regulation of vasculature development

GO:1901343

Any process that stops, prevents or reduces the frequency, rate or extent of vasculature development.

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Known genes in the process in rat Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "negative regulation of vasculature development"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "negative regulation of vasculature development" (in gray)

Name	Description	Probability	Func Analog Organism
Ccl4	chemokine (C-C motif) ligand 4	0.321
Il6	interleukin 6	0.282
Serpina3k	serine (or cysteine) peptidase inhibitor, clade A, member 3K	0.254
Ccl2	chemokine (C-C motif) ligand 2	0.239
Cxcl2	chemokine (C-X-C motif) ligand 2	0.177	Rat
Prdm2	PR domain containing 2, with ZNF domain	0.164
Fosl1	fos-like antigen 1	0.108
Ms4a2	membrane-spanning 4-domains, subfamily A, member 2 (Fc fragment of IgE, high affinity I, receptor for; beta polypeptide)	0.102
Alb	albumin	0.092
Dio2	deiodinase, iodothyronine, type II	0.089
Ahsg	alpha-2-HS-glycoprotein	0.088
Rup2	urinary protein 2	0.074
Asgr2	asialoglycoprotein receptor 2	0.068
Cxcl10	chemokine (C-X-C motif) ligand 10	0.063
Iapp	islet amyloid polypeptide	0.051
Map3k8	mitogen-activated protein kinase kinase kinase 8	0.051
Spp2	secreted phosphoprotein 2	0.050
Emcn	endomucin	0.050
Slc10a1	solute carrier family 10 (sodium/bile acid cotransporter family), member 1	0.045
Syt8	synaptotagmin VIII	0.042
Twist2	twist homolog 2 (Drosophila)	0.042
Fgf2	fibroblast growth factor 2	0.040
Mbl1	mannose-binding lectin (protein A) 1	0.036
LOC299282	Serine protease inhibitor	0.036	Rat
Pla2g2a	phospholipase A2, group IIA (platelets, synovial fluid)	0.035
Cxcl1	chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)	0.033	Rat
Cyp2c13	cytochrome P450, family 2, subfamily c, polypeptide 13	0.033
Edn1	endothelin 1	0.032
Prl3d1	Prolactin family 3, subfamily d, member 1	0.032
Proc	protein C	0.031
Serpind1	serpin peptidase inhibitor, clade D (heparin cofactor), member 1	0.030
Cyp4f4	cytochrome P450, family 4, subfamily f, polypeptide 4	0.029
Gpr116	G protein-coupled receptor 116	0.029
Ctsh	cathepsin H	0.029
Serpinb7	serpin peptidase inhibitor, clade B (ovalbumin), member 7	0.027
Tacr2	tachykinin receptor 2	0.027
Ltb4r2	leukotriene B4 receptor 2	0.024
Apoa5	apolipoprotein A-V	0.024
Ccr2	chemokine (C-C motif) receptor 2	0.022	Mouse
Pemt	phosphatidylethanolamine N-methyltransferase	0.022
Fgb	fibrinogen beta chain	0.022
Ncan	neurocan	0.021
Cxcr5	chemokine (C-X-C motif) receptor 5	0.021
Tnni1	troponin I type 1 (skeletal, slow)	0.021
Il9r	interleukin 9 receptor	0.020
Col10a1	collagen, type X, alpha 1	0.020
Hpx	hemopexin	0.020
Cmtm2a	CKLF-like MARVEL transmembrane domain containing 2A	0.020
Mbl2	mannose-binding lectin (protein C) 2	0.020
Ifit3	interferon-induced protein with tetratricopeptide repeats 3	0.020
Ngf	nerve growth factor (beta polypeptide)	0.019
Gucy1b2	guanylate cyclase 1, soluble, beta 2	0.018
Gfap	glial fibrillary acidic protein	0.018
Pitx3	paired-like homeodomain 3	0.018
Fgfr2	fibroblast growth factor receptor 2	0.018
Cit	citron	0.017
LOC100364500	RT1 class I, locus CE11-like	0.016
Il1a	interleukin 1 alpha	0.016
Cyp2b12	cytochrome P450, family 2, subfamily b, polypeptide 12	0.016
Has2	hyaluronan synthase 2	0.016
Apoh	apolipoprotein H (beta-2-glycoprotein I)	0.016	Human
Tnfsf4	tumor necrosis factor (ligand) superfamily, member 4	0.016
Kcnj4	potassium inwardly-rectifying channel, subfamily J, member 4	0.016
Ccl20	chemokine (C-C motif) ligand 20	0.016
Ptpn12	protein tyrosine phosphatase, non-receptor type 12	0.016
Gc	group specific component	0.016
Scpep1	serine carboxypeptidase 1	0.015
Nos3	nitric oxide synthase 3, endothelial cell	0.015
Cga	glycoprotein hormones, alpha polypeptide	0.015
Chrna6	cholinergic receptor, nicotinic, alpha 6	0.015
Slc2a3	solute carrier family 2 (facilitated glucose transporter), member 3	0.015
Il1rn	interleukin 1 receptor antagonist	0.015
Mmp12	matrix metallopeptidase 12	0.015
Wisp2	WNT1 inducible signaling pathway protein 2	0.015
Tdo2	tryptophan 2,3-dioxygenase	0.014
RGD1565859	RGD1565859	0.014
Apoa2	apolipoprotein A-II	0.014
Kcna3	potassium voltage-gated channel, shaker-related subfamily, member 3	0.014
Fgf14	fibroblast growth factor 14	0.014
Serpina11	serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 11	0.014	Rat
Olr416	olfactory receptor 416	0.014
Fga	fibrinogen alpha chain	0.014
Apcs	amyloid P component, serum	0.013
Mbtps1	membrane-bound transcription factor peptidase, site 1	0.013
Csrp3	cysteine and glycine-rich protein 3	0.013
Aqp8	aquaporin 8	0.013
Crhbp	corticotropin releasing hormone binding protein	0.013
Adora2a	adenosine A2a receptor	0.013
Celsr3	cadherin, EGF LAG seven-pass G-type receptor 3 (flamingo homolog, Drosophila)	0.013
Igfals	insulin-like growth factor binding protein, acid labile subunit	0.013
Folh1	folate hydrolase 1	0.013
Trim28	tripartite motif-containing 28	0.013
Cpa3	carboxypeptidase A3, mast cell	0.012
Testin	testin gene	0.012
Arl5c	ADP-ribosylation factor-like 5C	0.012
Tlr4	toll-like receptor 4	0.012
Atf3	activating transcription factor 3	0.012
RGD1308165	similar to hypothetical protein MGC17337	0.012
Col8a1	collagen, type VIII, alpha 1	0.012
Ms4a8a	membrane-spanning 4-domains, subfamily A, member 8A	0.012
Mcam	melanoma cell adhesion molecule	0.012
Ar	androgen receptor	0.011
Olr1	oxidized low density lipoprotein (lectin-like) receptor 1	0.011
Ccdc49	coiled-coil domain containing 49	0.010
Klf13	Kruppel-like factor 13	0.010
Hist1h2aa	histone cluster 1, H2aa	0.010