IMP
Process View
interleukin 1 biosynthetic process
The chemical reactions and pathways resulting in the formation of interleukin-1, an interleukin produced mainly by activated macrophages. It is involved in the inflammatory response, and is identified as an endogenous pyrogen.
Loading network...
In addition to gene-name show these genes:
Click on a gene's description to view its network relationships with genes known to be involved in "interleukin 1 biosynthetic process"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| Ccl3 | chemokine (C-C motif) ligand 3 | 0.883 | Rat | |
| Il1b | interleukin 1 beta | 0.837 | ||
| Ccl2 | chemokine (C-C motif) ligand 2 | 0.761 | ||
| Ccl4 | chemokine (C-C motif) ligand 4 | 0.723 | Rat | |
| Cxcl2 | chemokine (C-X-C motif) ligand 2 | 0.601 | ||
| Cxcl10 | chemokine (C-X-C motif) ligand 10 | 0.521 | ||
| Il6 | interleukin 6 | 0.491 | ||
| Reg3b | regenerating islet-derived 3 beta | 0.454 | ||
| Klrd1 | killer cell lectin-like receptor, subfamily D, member 1 | 0.447 | ||
| Cxcl1 | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) | 0.400 | ||
| Ccl20 | chemokine (C-C motif) ligand 20 | 0.366 | ||
| Neurl3 | neuralized homolog 3 (Drosophila) | 0.198 | ||
| Olr1 | oxidized low density lipoprotein (lectin-like) receptor 1 | 0.182 | ||
| Mmp3 | matrix metallopeptidase 3 | 0.165 | ||
| Mmp12 | matrix metallopeptidase 12 | 0.140 | ||
| Prf1 | perforin 1 (pore forming protein) | 0.112 | ||
| Nkg7 | natural killer cell group 7 sequence | 0.096 | ||
| Fosl1 | fos-like antigen 1 | 0.084 | ||
| Il1a | interleukin 1 alpha | 0.075 | ||
| Tnf | tumor necrosis factor (TNF superfamily, member 2) | 0.071 | ||
| Pdzk1ip1 | PDZK1 interacting protein 1 | 0.060 | ||
| Hpgds | hematopoietic prostaglandin D synthase | 0.058 | ||
| Stx11 | syntaxin 11 | 0.058 | ||
| Il1r2 | interleukin 1 receptor, type II | 0.049 | ||
| Plau | plasminogen activator, urokinase | 0.046 | ||
| Fcer1a | Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide | 0.044 | ||
| Serpine1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.038 | ||
| Fgr | Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog | 0.037 | ||
| Cd14 | CD14 molecule | 0.037 | ||
| Serpinb2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | 0.035 | ||
| Ccl7 | chemokine (C-C motif) ligand 7 | 0.033 | Rat | |
| Il2rb | interleukin 2 receptor, beta | 0.033 | ||
| Gzmk | granzyme K | 0.032 | ||
| Ubd | ubiquitin D | 0.032 | ||
| Arl5c | ADP-ribosylation factor-like 5C | 0.031 | ||
| Rsad2 | radical S-adenosyl methionine domain containing 2 | 0.030 | ||
| Gzmb | granzyme B | 0.029 | ||
| Tgm1 | transglutaminase 1, K polypeptide | 0.027 | ||
| Ccr2 | chemokine (C-C motif) receptor 2 | 0.026 | ||
| Nox4 | NADPH oxidase 4 | 0.024 | ||
| Map3k8 | mitogen-activated protein kinase kinase kinase 8 | 0.023 | ||
| Gzma | granzyme A | 0.022 | ||
| Cxcl11 | chemokine (C-X-C motif) ligand 11 | 0.022 | ||
| Gimap4 | GTPase, IMAP family member 4 | 0.021 | ||
| Junb | jun B proto-oncogene | 0.021 | ||
| Cdh17 | cadherin 17 | 0.020 | ||
| Pla2g2a | phospholipase A2, group IIA (platelets, synovial fluid) | 0.018 | ||
| Ch25h | cholesterol 25-hydroxylase | 0.018 | ||
| Rgs1 | regulator of G-protein signaling 1 | 0.016 | ||
| LOC689770 | similar to osteoclast inhibitory lectin | 0.015 | ||
| Il7r | interleukin 7 receptor | 0.015 | ||
| Cd8a | CD8a molecule | 0.014 | ||
| Xcl1 | chemokine (C motif) ligand 1 | 0.014 | Rat | |
| Steap1 | six transmembrane epithelial antigen of the prostate 1 | 0.014 | ||
| Tlr2 | toll-like receptor 2 | 0.014 | ||
| Birc3 | baculoviral IAP repeat-containing 3 | 0.013 | ||
| Slco1a5 | solute carrier organic anion transporter family, member 1a5 | 0.013 | ||
| Cst7 | cystatin F (leukocystatin) | 0.012 | ||
| Cldn7 | claudin 7 | 0.012 | ||
| Gpx2 | glutathione peroxidase 2 | 0.012 | ||
| Mcpt8 | mast cell protease 8 | 0.011 | ||
| Reg3g | regenerating islet-derived 3 gamma | 0.011 | ||
| Dpep1 | dipeptidase 1 (renal) | 0.011 | ||
| Prl7b1 | prolactin family 7, subfamily b, member 1 | 0.011 | ||
| Cela1 | chymotrypsin-like elastase family, member 1 | 0.010 | ||
| Lrrc17 | leucine rich repeat containing 17 | 0.010 | ||
| Fas | Fas (TNF receptor superfamily, member 6) | 0.010 |