IMP

Process View

Rattus norvegicus

24 genes annotated in rat

positive regulation of ion transmembrane transport

Any process that activates or increases the frequency, rate or extent of the directed movement of ions from one side of a membrane to the other.

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Known genes in the process in rat Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "positive regulation of ion transmembrane transport"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "positive regulation of ion transmembrane transport" (in gray)

Name	Description	Probability	Func Analog Organism
S100a10	S100 calcium binding protein A10	0.433	Rat
Anxa1	annexin A1	0.287
Anxa2	annexin A2	0.219
S100a6	S100 calcium binding protein A6	0.160	Rat
S100a4	S100 calcium-binding protein A4	0.137	Rat
Timp1	TIMP metallopeptidase inhibitor 1	0.090
Fgf14	fibroblast growth factor 14	0.078	Mouse
Plp2	proteolipid protein 2 (colonic epithelium-enriched)	0.072
Phkg1	phosphorylase kinase, gamma 1	0.069
Tspo	translocator protein	0.069
Slc6a17	solute carrier family 6 (neurotransmitter transporter), member 17	0.053
Lgals3	lectin, galactoside-binding, soluble, 3	0.053	Human
Sftpd	surfactant protein D	0.047
Cstb	cystatin B (stefin B)	0.042
Lgals1	lectin, galactoside-binding, soluble, 1	0.041
Atp1a2	ATPase, Na+/K+ transporting, alpha 2 polypeptide	0.040
Prl8a2	prolactin family 8, subfamily a, member 2	0.038
Slc34a1	solute carrier family 34 (sodium phosphate), member 1	0.036
LOC688549	hypothetical protein LOC688549	0.035
Sox17	SRY (sex determining region Y)-box 17	0.034
Pdyn	prodynorphin	0.034
Kcna6	potassium voltage gated channel, shaker related subfamily, member 6	0.034
Cel	carboxyl ester lipase	0.034
Dlg4	discs, large homolog 4 (Drosophila)	0.033
Crip	cysteine-rich intestinal protein	0.031
Dlgap3	discs, large (Drosophila) homolog-associated protein 3	0.031
Pnlip	pancreatic lipase	0.031
Shank1	SH3 and multiple ankyrin repeat domains 1	0.031
Atp1b2	ATPase, Na+/K+ transporting, beta 2 polypeptide	0.030
Aif1l	allograft inflammatory factor 1-like	0.029
Myl7	myosin, light chain 7, regulatory	0.029
Htr7	5-hydroxytryptamine (serotonin) receptor 7	0.028
Ccl2	chemokine (C-C motif) ligand 2	0.028
Grik3	glutamate receptor, ionotropic, kainate 3	0.028
Dcc	deleted in colorectal carcinoma	0.028
Mag	myelin-associated glycoprotein	0.027
RGD1565859	RGD1565859	0.027
Vdr	vitamin D (1,25- dihydroxyvitamin D3) receptor	0.027
Trpc4	transient receptor potential cation channel, subfamily C, member 4	0.026
Iapp	islet amyloid polypeptide	0.025
Kcnj11	potassium inwardly rectifying channel, subfamily J, member 11	0.025
Gast	gastrin	0.025
Pax6	paired box 6	0.025
Rph3a	rabphilin 3A	0.024
Adam2	ADAM metallopeptidase domain 2	0.024
Pomc	proopiomelanocortin	0.024
Myh6	myosin, heavy chain 6, cardiac muscle, alpha	0.023
Rims1	regulating synaptic membrane exocytosis 1	0.023
Serpini2	serine (or cysteine) peptidase inhibitor, clade I, member 2	0.023
Otud1	OTU domain containing 1	0.022
Cnga1	cyclic nucleotide gated channel alpha 1	0.022
Col9a2	collagen, type IX, alpha 2	0.022
Naaladl1	N-acetylated alpha-linked acidic dipeptidase-like 1	0.022
Cmtm2a	CKLF-like MARVEL transmembrane domain containing 2A	0.022
Ppard	peroxisome proliferator-activated receptor delta	0.022
St18	suppression of tumorigenicity 18	0.021
Aqp5	aquaporin 5	0.021
Pdia2	protein disulfide isomerase family A, member 2	0.021
RGD1564327	similar to integrin alpha 8	0.021
Tmem86a	transmembrane protein 86A	0.021
Bdnf	brain-derived neurotrophic factor	0.021
Mchr1	melanin-concentrating hormone receptor 1	0.021
Crhr1	corticotropin releasing hormone receptor 1	0.021
Gpr1	G protein-coupled receptor 1	0.021
Kcnj9	potassium inwardly-rectifying channel, subfamily J, member 9	0.021	Rat
Grin2b	glutamate receptor, ionotropic, N-methyl D-aspartate 2B	0.020
Kcnt1	potassium channel, subfamily T, member 1	0.020
Nfasc	neurofascin	0.020
Enpp6	ectonucleotide pyrophosphatase/phosphodiesterase 6	0.020
Abcc8	ATP-binding cassette, subfamily C (CFTR/MRP), member 8	0.020
Adra1a	adrenergic, alpha-1A-, receptor	0.019
Fgf16	fibroblast growth factor 16	0.019
Ctrc	chymotrypsin C (caldecrin)	0.019
Adrb1	adrenergic, beta-1-, receptor	0.019
Slc30a2	solute carrier family 30 (zinc transporter), member 2	0.019
Slc6a3	solute carrier family 6 (neurotransmitter transporter, dopamine), member 3	0.019
Casq2	calsequestrin 2 (cardiac muscle)	0.018
Ahnak	AHNAK nucleoprotein	0.018
Kcnh2	potassium voltage-gated channel, subfamily H (eag-related), member 2	0.018	Human
Prr13	proline rich 13	0.018
Sv2b	synaptic vesicle glycoprotein 2b	0.018
Gnaz	guanine nucleotide binding protein (G protein), alpha z polypeptide	0.018
Ar	androgen receptor	0.018
Anxa5	annexin A5	0.018
Ucp3	uncoupling protein 3 (mitochondrial, proton carrier)	0.017
Ckm	creatine kinase, muscle	0.017
Ms4a8a	membrane-spanning 4-domains, subfamily A, member 8A	0.017
Mep1a	meprin 1 alpha	0.017
Chrna6	cholinergic receptor, nicotinic, alpha 6	0.017
Ptprn2	protein tyrosine phosphatase, receptor type, N polypeptide 2	0.017
Atxn1	ataxin 1	0.017
Tns4	tensin 4	0.017
Gja4	gap junction protein, alpha 4	0.017
Bdkrb2	bradykinin receptor B2	0.017
Ncan	neurocan	0.017
Kcnk13	potassium channel, subfamily K, member 13	0.017
LOC207127	similar to preprotein translocase	0.017
Slc8a1	solute carrier family 8 (sodium/calcium exchanger), member 1	0.017
Epor	erythropoietin receptor	0.017
Ddn	dendrin	0.017
Pnliprp2	pancreatic lipase-related protein 2	0.016
Col11a2	collagen, type XI, alpha 2	0.016
Cd9	CD9 molecule	0.016
Atp1b1	ATPase, Na+/K+ transporting, beta 1 polypeptide	0.016
RGD1564664	similar to LOC387763 protein	0.016
Rab3b	RAB3B, member RAS oncogene family	0.016
Aqp2	aquaporin 2 (collecting duct)	0.016
Kif12	kinesin family member 12	0.016
Rftn2	raftlin family member 2	0.016
Mgp	matrix Gla protein	0.016
Plaur	plasminogen activator, urokinase receptor	0.016
Cap2	CAP, adenylate cyclase-associated protein, 2 (yeast)	0.016
Pgc	progastricsin (pepsinogen C)	0.016
Cav3	caveolin 3	0.016
Lrrc4b	leucine rich repeat containing 4B	0.016
Arnt2	aryl hydrocarbon receptor nuclear translocator 2	0.016
Pdk2	pyruvate dehydrogenase kinase, isozyme 2	0.016
Inha	inhibin alpha	0.016
Testin	testin gene	0.016
Sag	S-antigen; retina and pineal gland (arrestin)	0.016
Adcy5	adenylate cyclase 5	0.016
Slc2a4	solute carrier family 2 (facilitated glucose transporter), member 4	0.016
Gpr6	G protein-coupled receptor 6	0.015
Syt8	synaptotagmin VIII	0.015
Mc5r	melanocortin 5 receptor	0.015
Atp2b4	ATPase, Ca++ transporting, plasma membrane 4	0.015
Rasd2	RASD family, member 2	0.015
Bcl2	B-cell CLL/lymphoma 2	0.015
Nkx2-5	NK2 transcription factor related, locus 5 (Drosophila)	0.015	Mouse
Fcer2	Fc fragment of IgE, low affinity II, receptor for (CD23)	0.015
Lifr	leukemia inhibitory factor receptor alpha	0.015
Asph	aspartate-beta-hydroxylase	0.015
Sncg	synuclein, gamma (breast cancer-specific protein 1)	0.015
Klk1b3	kallikrein 1-related peptidase b3	0.015
Anxa4	annexin A4	0.015
Adcyap1r1	adenylate cyclase activating polypeptide 1 receptor 1	0.015
Cd79b	Cd79b molecule, immunoglobulin-associated beta	0.015
Chdh	choline dehydrogenase	0.015
Il6	interleukin 6	0.015
Klk1c10l2	kallikrein 1-related peptidase c10-like 2	0.015
Pdc	phosducin	0.015
Nrxn2	neurexin 2	0.015
Grk4	G protein-coupled receptor kinase 4	0.015
Pip5k1c	phosphatidylinositol-4-phosphate 5-kinase, type I, gamma	0.015
Cacng8	calcium channel, voltage-dependent, gamma subunit 8	0.015
Htr5a	5-hydroxytryptamine (serotonin) receptor 5A	0.015	Rat
Fgf2	fibroblast growth factor 2	0.014
Kcna5	potassium voltage-gated channel, shaker-related subfamily, member 5	0.014
Kcnq3	potassium voltage-gated channel, KQT-like subfamily, member 3	0.014
Fgf10	fibroblast growth factor 10	0.014
Thbd	thrombomodulin	0.014
Kcnd3	potassium voltage-gated channel, Shal-related subfamily, member 3	0.014
Folh1	folate hydrolase 1	0.014
Prl3b1	Prolactin family 3, subfamily b, member 1	0.014
Ptpru	protein tyrosine phosphatase, receptor type, U	0.014
Foxd3	forkhead box D3	0.014
Rorb	RAR-related orphan receptor B	0.014
Tnp1	transition protein 1	0.014
Csrnp2	cysteine-serine-rich nuclear protein 2	0.014
Edn1	endothelin 1	0.014
Naglt1	Na+ dependent glucose transporter 1	0.014
Pdzk1ip1	PDZK1 interacting protein 1	0.014
Cacna1a	calcium channel, voltage-dependent, P/Q type, alpha 1A subunit	0.014
Spt1	salivary protein 1	0.014
Ivd	isovaleryl coenzyme A dehydrogenase	0.014
Drd3	dopamine receptor D3	0.014
Edn2	endothelin 2	0.013
Cd63	Cd63 molecule	0.013
Plp1	proteolipid protein 1	0.013
Kcnab2	potassium voltage-gated channel, shaker-related subfamily, beta member 2	0.013
Capg	capping protein (actin filament), gelsolin-like	0.013
Spata9	spermatogenesis associated 9	0.013
Tshr	thyroid stimulating hormone receptor	0.013
Apobec2	apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2	0.013
Prkce	protein kinase C, epsilon	0.013
Kcng2	potassium voltage-gated channel, subfamily G, member 2	0.013
Glp1r	glucagon-like peptide 1 receptor	0.013
Clcn1	chloride channel 1	0.013
Slc2a3	solute carrier family 2 (facilitated glucose transporter), member 3	0.013
Ocm	oncomodulin	0.013
Clec11a	C-type lectin domain family 11, member a	0.013
Hrh1	histamine receptor H 1	0.013
Adm	adrenomedullin	0.013
Pmfbp1	polyamine modulated factor 1 binding protein 1	0.013
Necab2	N-terminal EF-hand calcium binding protein 2	0.013
Slit2	slit homolog 2 (Drosophila)	0.013
Sox12	SRY (sex determining region Y)-box 12	0.013
P2ry4	pyrimidinergic receptor P2Y, G-protein coupled, 4	0.013
Hbe2	hemoglobin, epsilon 2	0.012
Arhgef7	Rho guanine nucleotide exchange factor (GEF7)	0.012
Gpr37l1	G protein-coupled receptor 37-like 1	0.012
Sct	secretin	0.012
Dnah7	dynein, axonemal, heavy polypeptide 7	0.012
Hebp1	heme binding protein 1	0.012
Cdh17	cadherin 17	0.012
B3gat1	beta-1,3-glucuronyltransferase 1 (glucuronosyltransferase P)	0.012
Gnb3	guanine nucleotide binding protein (G protein), beta polypeptide 3	0.012
Nxph3	neurexophilin 3	0.012
Cma1	chymase 1, mast cell	0.012
Aqp4	aquaporin 4	0.012
Gfra2	GDNF family receptor alpha 2	0.012
Ngb	neuroglobin	0.012
Chrna7	cholinergic receptor, nicotinic, alpha 7	0.012
Ppp1r1a	protein phosphatase 1, regulatory (inhibitor) subunit 1A	0.012
Flt1	FMS-related tyrosine kinase 1	0.012
LOC60591	calcium-activated potassium channel beta subunit	0.012
Kif1c	kinesin family member 1C	0.012
Gabrb3	gamma-aminobutyric acid (GABA) A receptor, beta 3	0.012
Kcnj5	potassium inwardly-rectifying channel, subfamily J, member 5	0.012	Rat
Glra1	glycine receptor, alpha 1	0.012
Neurl2	neuralized homolog 2 (Drosophila)	0.012
Catsper2	cation channel, sperm associated 2	0.011
Gstm1	glutathione S-transferase mu 1	0.011
Bcl2l10	BCL2-like 10 (apoptosis facilitator)	0.011
Vom1r101	vomeronasal 1 receptor 101	0.011
Myo1a	myosin IA	0.011
Hr	hairless	0.011
Pclo	piccolo (presynaptic cytomatrix protein)	0.011
Kcnk3	potassium channel, subfamily K, member 3	0.011
Zp1	zona pellucida glycoprotein 1 (sperm receptor)	0.011
Gria1	glutamate receptor, ionotropic, AMPA 1	0.011
Foxe3	forkhead box E3	0.011
Slc16a3	solute carrier family 16, member 3 (monocarboxylic acid transporter 4)	0.011
Ascl1	achaete-scute complex homolog 1 (Drosophila)	0.011
Chrm2	cholinergic receptor, muscarinic 2	0.011
Chia	chitinase, acidic	0.011
Sftpa1	surfactant protein A1	0.011
Dspp	dentin sialophosphoprotein	0.011
Pxmp2	peroxisomal membrane protein 2	0.011
Plb1	phospholipase B1	0.011
Sstr1	somatostatin receptor 1	0.011
Angpt2	angiopoietin 2	0.011
Nlgn2	neuroligin 2	0.011
Ngf	nerve growth factor (beta polypeptide)	0.011
Crygd	crystallin, gamma D	0.011
Hnmt	histamine N-methyltransferase	0.011
Gja1	gap junction protein, alpha 1	0.011
Klrb1c	killer cell lectin-like receptor subfamily B member 1C	0.011
Shbg	sex hormone binding globulin	0.011
Tnni1	troponin I type 1 (skeletal, slow)	0.011
Odf4	outer dense fiber of sperm tails 4	0.011
Cckar	cholecystokinin A receptor	0.011
Accn2	amiloride-sensitive cation channel 2, neuronal	0.011	Rat
Dlgap2	discs, large (Drosophila) homolog-associated protein 2	0.011
Fshb	follicle stimulating hormone, beta polypeptide	0.011
Htr1d	5-hydroxytryptamine (serotonin) receptor 1D	0.011	Rat
Scgb1c1	secretoglobin, family 1C, member 1	0.010
Chrnb2	cholinergic receptor, nicotinic, beta 2 (neuronal)	0.010
Ltb4r2	leukotriene B4 receptor 2	0.010
Adam5	a disintegrin and metallopeptidase domain 5	0.010
Dhrs9	dehydrogenase/reductase (SDR family) member 9	0.010
Prkcg	protein kinase C, gamma	0.010
Chrnb3	cholinergic receptor, nicotinic, beta 3	0.010
Clic1	chloride intracellular channel 1	0.010
Htr2a	5-hydroxytryptamine (serotonin) receptor 2A	0.010	Rat
Kcnj10	potassium inwardly-rectifying channel, subfamily J, member 10	0.010	Rat
Sulf1	sulfatase 1	0.010
Vim	vimentin	0.010
Kctd13	potassium channel tetramerisation domain containing 13	0.010
Asb2	ankyrin repeat and SOCS box-containing 2	0.010
Obscn	obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF	0.010
Alox5ap	arachidonate 5-lipoxygenase activating protein	0.010
Grm2	glutamate receptor, metabotropic 2	0.010
Cd28	Cd28 molecule	0.010
Cntn2	contactin 2 (axonal)	0.010
Olr416	olfactory receptor 416	0.010
Capn8	calpain 8	0.010
Calca	calcitonin-related polypeptide alpha	0.010
Gja3	gap junction protein, alpha 3	0.010
Adarb2	adenosine deaminase, RNA-specific, B2	0.010
Mmp9	matrix metallopeptidase 9	0.010
Myo9a	myosin IXA	0.010
Ndufs4	NADH dehydrogenase (ubiquinone) Fe-S protein 4	0.010
Tnni3	troponin I type 3 (cardiac)	0.010
Acaa1b	acetyl-Coenzyme A acyltransferase 1B	0.010
Defb22	defensin beta 22	0.010
Nptxr	neuronal pentraxin receptor	0.010
Trhr2	thyrotropin releasing hormone receptor 2	0.010
S100a11	S100 calcium binding protein A11 (calizzarin)	0.010	Rat