IMP

Process View

Rattus norvegicus

16 genes annotated in rat

chronic inflammatory response

Inflammation of prolonged duration (weeks or months) in which active inflammation, tissue destruction, and attempts at repair are proceeding simultaneously. Although it may follow acute inflammation, chronic inflammation frequently begins insidiously, as a low-grade, smoldering, often asymptomatic response.

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Known genes in the process in rat Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "chronic inflammatory response"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "chronic inflammatory response" (in gray)

Name	Description	Probability	Func Analog Organism
S100a6	S100 calcium binding protein A6	0.872	Rat
Ccl2	chemokine (C-C motif) ligand 2	0.786
S100a8	S100 calcium binding protein A8	0.720
Lgals3	lectin, galactoside-binding, soluble, 3	0.511
S100a9	S100 calcium binding protein A9	0.432
Il1a	interleukin 1 alpha	0.347
Anxa1	annexin A1	0.345
Il1b	interleukin 1 beta	0.328
Sell	selectin L	0.323
Il8rb	interleukin 8 receptor, beta	0.218	Rat
Ccl4	chemokine (C-C motif) ligand 4	0.187	Rat
S100a10	S100 calcium binding protein A10	0.185	Rat
Anxa2	annexin A2	0.162
Il6	interleukin 6	0.120
Igsf6	immunoglobulin superfamily, member 6	0.113
Mbp	myelin basic protein	0.110
Timp1	TIMP metallopeptidase inhibitor 1	0.108
Il2rb	interleukin 2 receptor, beta	0.104
Tspo	translocator protein	0.094
Bcl2a1d	B-cell leukemia/lymphoma 2 related protein A1d	0.087
Fcnb	ficolin B	0.086
Pla2g2a	phospholipase A2, group IIA (platelets, synovial fluid)	0.084
Ccl3	chemokine (C-C motif) ligand 3	0.072	Rat
Cd14	CD14 molecule	0.067
S100a4	S100 calcium-binding protein A4	0.063	Rat
Cxcl2	chemokine (C-X-C motif) ligand 2	0.055
Neurl3	neuralized homolog 3 (Drosophila)	0.052
Ccl20	chemokine (C-C motif) ligand 20	0.052	Rat
Crip	cysteine-rich intestinal protein	0.047
Cxcl1	chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)	0.046
Gzmb	granzyme B	0.044
Lgals1	lectin, galactoside-binding, soluble, 1	0.044
Ccr5	chemokine (C-C motif) receptor 5	0.042
Psp	parotid secretory protein	0.042
Plp2	proteolipid protein 2 (colonic epithelium-enriched)	0.039
Klrd1	killer cell lectin-like receptor, subfamily D, member 1	0.039
RGD1309537	similar to Myosin regulatory light chain 2-A, smooth muscle isoform (Myosin RLC-A)	0.035
Fxyd1	FXYD domain-containing ion transport regulator 1	0.034
Fcer1a	Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide	0.031
Gzmk	granzyme K	0.031
Krt4	keratin 4	0.031
Steap1	six transmembrane epithelial antigen of the prostate 1	0.029
Nkg7	natural killer cell group 7 sequence	0.028
Reg3g	regenerating islet-derived 3 gamma	0.028
Cxcl10	chemokine (C-X-C motif) ligand 10	0.027
Il12b	interleukin 12B	0.026
Gsta4	glutathione S-transferase alpha 4	0.026
Prss22	protease, serine, 22	0.026
Ccl22	chemokine (C-C motif) ligand 22	0.026
Tgm1	transglutaminase 1, K polypeptide	0.025
Mmp3	matrix metallopeptidase 3	0.025
Gsta3	glutathione S-transferase A3	0.023
Cd86	CD86 molecule	0.022
LOC287167	globin, alpha	0.022
Xcl1	chemokine (C motif) ligand 1	0.022	Rat
Cd40lg	CD40 ligand	0.020
Cd8a	CD8a molecule	0.020
Mmp8	matrix metallopeptidase 8	0.020
Tm4sf1	transmembrane 4 L six family member 1	0.018
Faslg	Fas ligand (TNF superfamily, member 6)	0.018
Nos2	nitric oxide synthase 2, inducible	0.018
Pf4	platelet factor 4	0.018
Lilrb4	leukocyte immunoglobulin-like receptor, subfamily B, member 4	0.018
Mgp	matrix Gla protein	0.018
Tcrb	T-cell receptor beta chain	0.017
Cxcl3	chemokine (C-X-C motif) ligand 3	0.017
Ccl7	chemokine (C-C motif) ligand 7	0.017	Rat
Glycam1	glycosylation dependent cell adhesion molecule 1	0.017
Gpx2	glutathione peroxidase 2	0.017
RT1-Ba	RT1 class II, locus Ba	0.016
Socs3	suppressor of cytokine signaling 3	0.016
Pde6h	phosphodiesterase 6H, cGMP-specific, cone, gamma	0.016
Selp	selectin P	0.016
Tnf	tumor necrosis factor (TNF superfamily, member 2)	0.016	Mouse
Mgst2	microsomal glutathione S-transferase 2	0.016
Olr1	oxidized low density lipoprotein (lectin-like) receptor 1	0.015
Fosl1	fos-like antigen 1	0.015
Il1rn	interleukin 1 receptor antagonist	0.015
Htr6	5-hydroxytryptamine (serotonin) receptor 6	0.015
Ptafr	platelet-activating factor receptor	0.014
Ifi204	interferon activated gene 204	0.014
Tlr7	toll-like receptor 7	0.014
Vcan	versican	0.014
Iapp	islet amyloid polypeptide	0.014
Olr1082	olfactory receptor 1082	0.013
S100a13	S100 calcium binding protein A13	0.013
Angpt2	angiopoietin 2	0.013
Edn1	endothelin 1	0.013
Tnfrsf4	tumor necrosis factor receptor superfamily, member 4	0.013
Gfap	glial fibrillary acidic protein	0.013
Sele	selectin E	0.013
RT1-Bb	RT1 class II, locus Bb	0.013
Anxa5	annexin A5	0.013
Cstb	cystatin B (stefin B)	0.013
Clec9a	C-type lectin domain family 9, member a	0.013
Tcp11	t-complex protein 11	0.013
Gabrg1	gamma-aminobutyric acid (GABA) A receptor, gamma 1	0.013
Cnr2	cannabinoid receptor 2 (macrophage)	0.013
Grm6	glutamate receptor, metabotropic 6	0.012
Stx11	syntaxin 11	0.012
Ccr1	chemokine (C-C motif) receptor 1	0.012
Fgf11	fibroblast growth factor 11	0.012
Olah	oleoyl-ACP hydrolase	0.012
LOC24906	RoBo-1	0.011
Nradd	neurotrophin receptor associated death domain	0.011
Sftpc	surfactant protein C	0.011
Lyz2	lysozyme 2	0.011
Ncr1	natural cytotoxicity triggering receptor 1	0.011
Serpinb1a	serine (or cysteine) proteinase inhibitor, clade B, member 1a	0.011
Myl7	myosin, light chain 7, regulatory	0.011
Adora2a	adenosine A2a receptor	0.011
Tff1	trefoil factor 1	0.011
Glud1	glutamate dehydrogenase 1	0.011
Tax1bp3	Tax1 (human T-cell leukemia virus type I) binding protein 3	0.011
Lst1	leukocyte specific transcript 1	0.011
Prp15	proline-rich protein 15	0.011
LOC683156	similar to testicular serine protease 2	0.010
Serpinb6a	serine (or cysteine) peptidase inhibitor, clade B, member 6a	0.010
Cd63	Cd63 molecule	0.010
Il1r2	interleukin 1 receptor, type II	0.010
Tfpi2	tissue factor pathway inhibitor 2	0.010
Gimap5	GTPase, IMAP family member 5	0.010
Serpine1	serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1	0.010
Gpr20	G protein-coupled receptor 20	0.010
Rplp1	ribosomal protein, large, P1	0.010
Serpine2	serine (or cysteine) peptidase inhibitor, clade E, member 2	0.010
Cd5	Cd5 molecule	0.010
LOC680988	similar to ribosomal protein S12	0.010
Arl5c	ADP-ribosylation factor-like 5C	0.010