IMP
Process View
fractalkine metabolic process
The chemical reactions and pathways involving fractalkine, a chemokine involved in the control of the key regulatory mechanisms of cell trafficking at sites of inflammation. It exists as a secreted protein and in a membrane-bound form, and exhibits a novel C-X-X-X-C cysteine signature motif. The counterpart of human fractalkine is murine neurotactin; fractalkine is also referred to as CX3C membrane-anchored chemokine or ABCD-3 and has been renamed CX3CL1.
Loading network...
In addition to gene-name show these genes:
Click on a gene's description to view its network relationships with genes known to be involved in "fractalkine metabolic process"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| Star | steroidogenic acute regulatory protein | 0.643 | ||
| Akr1c18 | aldo-keto reductase family 1, member C18 | 0.482 | ||
| Cubn | cubilin (intrinsic factor-cobalamin receptor) | 0.138 | ||
| Sult1c3 | sulfotransferase family, cytosolic, 1C, member 3 | 0.100 | ||
| Cst12 | cystatin 12 | 0.089 | ||
| LOC293989 | cytochrome P450-like | 0.087 | ||
| Spt1 | salivary protein 1 | 0.076 | ||
| Hes2 | hairy and enhancer of split 2 (Drosophila) | 0.072 | ||
| Hsd3b1 | hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 | 0.055 | ||
| Apoa2 | apolipoprotein A-II | 0.054 | ||
| Fam108b1 | family with sequence similarity 108, member B1 | 0.052 | ||
| Vtcn1 | V-set domain containing T cell activation inhibitor 1 | 0.051 | ||
| Gmeb2 | glucocorticoid modulatory element binding protein 2 | 0.047 | ||
| Prss3 | protease, serine, 3 | 0.047 | ||
| Omd | osteomodulin | 0.045 | ||
| Hao2 | hydroxyacid oxidase 2 (long chain) | 0.045 | ||
| Chrna3 | cholinergic receptor, nicotinic, alpha 3 | 0.042 | ||
| Svs5 | seminal vesicle secretory protein 5 | 0.039 | ||
| Prl7d1 | prolactin family 7, subfamily d, member 1 | 0.034 | ||
| Scgb2a1 | secretoglobin, family 2A, member 1 | 0.032 | ||
| Sostdc1 | sclerostin domain containing 1 | 0.030 | ||
| Zadh2 | zinc binding alcohol dehydrogenase, domain containing 2 | 0.030 | ||
| Cyp4b1 | cytochrome P450, family 4, subfamily b, polypeptide 1 | 0.029 | ||
| Aqp8 | aquaporin 8 | 0.027 | ||
| Smpx | small muscle protein, X-linked | 0.027 | ||
| RGD1304731 | similar to RIKEN cDNA 5330437I02 gene | 0.027 | ||
| Csrp3 | cysteine and glycine-rich protein 3 | 0.027 | ||
| Vom2r31 | vomeronasal 2 receptor, 31 | 0.026 | ||
| Lalba | lactalbumin, alpha | 0.024 | ||
| Cybrd1 | cytochrome b reductase 1 | 0.023 | ||
| Cdcp1 | CUB domain containing protein 1 | 0.023 | ||
| Slc9a3 | solute carrier family 9 (sodium/hydrogen exchanger), member 3 | 0.022 | ||
| Shbg | sex hormone binding globulin | 0.021 | ||
| Cacna1f | calcium channel, voltage-dependent, L type, alpha 1F subunit | 0.021 | ||
| Cd79b | Cd79b molecule, immunoglobulin-associated beta | 0.021 | ||
| Asb11 | ankyrin repeat and SOCS box-containing 11 | 0.020 | ||
| Gjb3 | gap junction protein, beta 3 | 0.020 | ||
| Cgm4 | carcinoembryonic antigen gene family 4 | 0.020 | ||
| Hbg1 | hemoglobin, gamma A | 0.019 | ||
| Cyp11b1 | cytochrome P450, family 11, subfamily b, polypeptide 1 | 0.019 | Rat | |
| Kcnk9 | potassium channel, subfamily K, member 9 | 0.018 | ||
| Fcer1a | Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide | 0.018 | ||
| Sult1b1 | sulfotransferase family, cytosolic, 1B, member 1 | 0.018 | ||
| Drd1a | dopamine receptor D1A | 0.018 | ||
| Vpreb3 | pre-B lymphocyte 3 | 0.018 | ||
| Slc9a4 | solute carrier family 9 (sodium/hydrogen exchanger), member 4 | 0.017 | ||
| Odf1 | outer dense fiber of sperm tails 1 | 0.017 | ||
| Calcr | calcitonin receptor | 0.017 | ||
| Pla2g5 | phospholipase A2, group V | 0.017 | ||
| Nr0b1 | nuclear receptor subfamily 0, group B, member 1 | 0.017 | ||
| Crisp2 | cysteine-rich secretory protein 2 | 0.017 | ||
| Ckm | creatine kinase, muscle | 0.016 | ||
| Cyp17a1 | cytochrome P450, family 17, subfamily a, polypeptide 1 | 0.016 | ||
| Fut1 | fucosyltransferase 1 | 0.016 | ||
| F2rl2 | coagulation factor II (thrombin) receptor-like 2 | 0.016 | ||
| Pla2g1b | phospholipase A2, group IB, pancreas | 0.016 | ||
| Vip | vasoactive intestinal peptide | 0.016 | ||
| Chrna10 | cholinergic receptor, nicotinic, alpha 10 | 0.015 | ||
| Wfdc6a | WAP four-disulfide core domain 6A | 0.015 | ||
| Vom1r105 | vomeronasal 1 receptor 105 | 0.015 | ||
| Atp4b | ATPase, H+/K+ exchanging, beta polypeptide | 0.015 | ||
| Naglt1 | Na+ dependent glucose transporter 1 | 0.014 | ||
| Prl5a1 | prolactin family 5, subfamily a, member 1 | 0.014 | ||
| Ucp1 | uncoupling protein 1 (mitochondrial, proton carrier) | 0.014 | ||
| Stag3 | stromal antigen 3 | 0.014 | ||
| Ibsp | integrin-binding sialoprotein | 0.014 | ||
| Vcsa2 | variable coding sequence A2 | 0.014 | ||
| Rln1 | relaxin 1 | 0.014 | ||
| Ppyr1 | pancreatic polypeptide receptor 1 | 0.013 | ||
| Nlrp6 | NLR family, pyrin domain containing 6 | 0.013 | ||
| Tnni3k | TNNI3 interacting kinase | 0.013 | ||
| Tacr2 | tachykinin receptor 2 | 0.013 | ||
| Cyp3a2 | cytochrome P450, family 3, subfamily a, polypeptide 2 | 0.013 | ||
| LOC100360403 | ATP-binding cassette, sub-family C, member 9-like | 0.013 | ||
| Clca4 | chloride channel accessory 4 | 0.013 | ||
| Scnn1g | sodium channel, nonvoltage-gated 1, gamma | 0.013 | ||
| Cyp3a18 | cytochrome P450, family 3, subfamily a, polypeptide 18 | 0.013 | ||
| Spink8 | serine peptidase inhibitor, Kazal type 8 | 0.013 | ||
| Si | sucrase-isomaltase (alpha-glucosidase) | 0.012 | ||
| Adipoq | adiponectin, C1Q and collagen domain containing | 0.012 | ||
| Pparg | peroxisome proliferator-activated receptor gamma | 0.012 | ||
| Slc22a2 | solute carrier family 22 (organic cation transporter), member 2 | 0.012 | ||
| Hcn1 | hyperpolarization-activated cyclic nucleotide-gated potassium channel 1 | 0.012 | ||
| Gucy2f | guanylate cyclase 2F | 0.012 | ||
| Kcnj15 | potassium inwardly-rectifying channel, subfamily J, member 15 | 0.012 | ||
| LOC494499 | LOC494499 protein | 0.012 | ||
| Slc22a1 | solute carrier family 22 (organic cation transporter), member 1 | 0.012 | ||
| Sycp3 | synaptonemal complex protein 3 | 0.011 | ||
| Atp2c2 | ATPase, Ca++ transporting, type 2C, member 2 | 0.011 | ||
| Mtrr | 5-methyltetrahydrofolate-homocysteine methyltransferase reductase | 0.011 | ||
| Sult1a1 | sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 | 0.011 | ||
| Cox6a2 | cytochrome c oxidase, subunit VIa, polypeptide 2 | 0.011 | ||
| Ppp3r2 | protein phosphatase 3, regulatory subunit B, beta isoform | 0.011 | ||
| Cited1 | Cbp/p300-interacting transactivator with Glu/Asp-rich carboxy-terminal domain 1 | 0.011 | ||
| Pdha2 | pyruvate dehydrogenase (lipoamide) alpha 2 | 0.011 | ||
| Tipin | timeless interacting protein | 0.011 | ||
| Xkr4 | XK, Kell blood group complex subunit-related family, member 4 | 0.010 | ||
| Tgm3 | transglutaminase 3, E polypeptide | 0.010 | ||
| Serpinb3a | serine (or cysteine) peptidase inhibitor, clade B (ovalbumin), member 3A | 0.010 | ||
| Ttr | transthyretin | 0.010 | ||
| Tore | trispanning orphan | 0.010 | ||
| Tdrd1 | tudor domain containing 1 | 0.010 |