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Danio rerio
0 genes annotated in zebrafish
osteogenesis imperfecta
DOID:12347
An osteochondrodysplasia that has material basis in a deficiency in type-I collagen which results in brittle bones and defective connective tissue.
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In addition to gene-name show these genes:
Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| sparc | secreted acidic cysteine rich glycoprotein | 0.833 | ||
| col1a1a | collagen, type I, alpha 1a | 0.692 | Human | |
| col1a2 | collagen, type I, alpha 2 | 0.410 | Human | |
| col5a1 | procollagen, type V, alpha 1 | 0.279 | ||
| cyp26b1 | cytochrome P450, family 26, subfamily b, polypeptide 1 | 0.185 | ||
| col5a2l | collagen, type V, alpha 2-like | 0.147 | ||
| dcn | decorin | 0.094 | ||
| col1a1b | collagen, type I, alpha 1b | 0.093 | Human | |
| col12a1 | collagen, type XII, alpha 1 | 0.086 | ||
| postn | periostin, osteoblast specific factor | 0.079 | ||
| col10a1 | collagen, type X, alpha 1 | 0.043 | ||
| wnt4a | wingless-type MMTV integration site family, member 4a | 0.033 | ||
| lamb1a | laminin, beta 1a | 0.030 | ||
| col6a3 | collagen, type VI, alpha 3 | 0.027 | ||
| pdgfrl | platelet-derived growth factor receptor-like | 0.023 | ||
| ihha | Indian hedgehog homolog a | 0.022 | ||
| rcn3 | reticulocalbin 3, EF-hand calcium binding domain | 0.021 | ||
| cx43 | connexin 43 | 0.019 | ||
| mmp14a | matrix metalloproteinase 14a (membrane-inserted) | 0.018 | ||
| mylz2 | myosin, light polypeptide 2, skeletal muscle | 0.018 | ||
| bglap | bone gamma-carboxyglutamate (gla) protein | 0.016 | ||
| fstl1b | follistatin-like 1b | 0.015 | ||
| pmp22a | peripheral myelin protein 22a | 0.014 | ||
| lect1 | leukocyte cell derived chemotaxin 1 | 0.013 | ||
| LOC100334210 | growth/differentiation factor 5-like | 0.012 | ||
| mmp2 | matrix metalloproteinase 2 | 0.012 | ||
| tgfbi | transforming growth factor, beta-induced | 0.012 | ||
| runx2a | runt-related transcription factor 2a | 0.012 | ||
| fras1 | Fraser syndrome 1 | 0.012 | ||
| runx2b | runt-related transcription factor 2b | 0.011 | ||
| zgc:111821 | zgc:111821 | 0.010 |