The network for 'regulation of hippo signaling' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

regulation of hippo signaling

Any process that modulates the frequency, rate or extent of hippo signaling.

Drosophila melanogaster
Name Description Probability Func Analog Organism
sav salvador 0.774
wts warts 0.760
hpo hippo 0.684
Ten-m Tenascin major 0.189
Smr Smrter 0.143
mask multiple ankyrin repeats single KH domain 0.128
path pathetic 0.124
scrib scribbled 0.064
mnb minibrain 0.063
nct nicastrin 0.063
dgo diego 0.060
ft fat 0.054
ed echinoid 0.053
CG8888 CG8888 gene product from transcript CG8888-RA 0.051
dlt discs lost 0.044
CG5794 CG5794 gene product from transcript CG5794-RB 0.041
rok Rho-kinase 0.035
fj four-jointed 0.032
PRL-1 CG4993 gene product from transcript CG4993-RB 0.029
kibra kibra ortholog 0.029
yki yorkie 0.028
CG9772 CG9772 gene product from transcript CG9772-RB 0.028
Tao-1 CG14217 gene product from transcript CG14217-RF 0.027
skpC CG11941 gene product from transcript CG11941-RA 0.026
melt melted 0.026
luna CG33473 gene product from transcript CG33473-RB 0.025
CG14317 CG14317 gene product from transcript CG14317-RA 0.024
arr arrow 0.024
Sos Son of sevenless 0.023
Cpr72Ea Cuticular protein 72Ea 0.022
X11L CG5675 gene product from transcript CG5675-RB 0.021
Pp2B-14D Protein phosphatase 2B at 14D 0.021
CG3021 CG3021 gene product from transcript CG3021-RA 0.020
unk unkempt 0.020
flfl falafel 0.020
nej nejire 0.020
dco discs overgrown 0.019
CG13114 CG13114 gene product from transcript CG13114-RB 0.018
slik Sterile20-like kinase 0.018
Act87E Actin 87E 0.018
CG32372 CG32372 gene product from transcript CG32372-RA 0.018
CG31869 CG31869 gene product from transcript CG31869-RA 0.018
msn misshapen 0.017
ds dachsous 0.015
sut1 sugar transporter 1 0.015
CG9090 CG9090 gene product from transcript CG9090-RA 0.014
Gef26 CG9491 gene product from transcript CG9491-RB 0.014
hep hemipterous 0.014
cindr CIN85 and CD2AP orthologue 0.014
crb crumbs 0.013
Axud1 CG4272 gene product from transcript CG4272-RA 0.013
pico CG11940 gene product from transcript CG11940-RA 0.013
CG30263 CG30263 gene product from transcript CG30263-RB 0.013
CG4911 CG4911 gene product from transcript CG4911-RA 0.013
par-1 CG8201 gene product from transcript CG8201-RA 0.013
CG5001 CG5001 gene product from transcript CG5001-RA 0.012
Prp38 pre-mRNA processing factor 38 0.012
Unc-76 CG3981 gene product from transcript CG3981-RB 0.012
CG4674 CG4674 gene product from transcript CG4674-RA 0.012
kek5 kekkon5 0.012
CG13085 CG13085 gene product from transcript CG13085-RA 0.012
Hs6st Heparan sulfate 6-O-sulfotransferase 0.012
CG8483 CG8483 gene product from transcript CG8483-RA 0.012
CG12581 CG12581 gene product from transcript CG12581-RA 0.012
Caf1-180 CG12109 gene product from transcript CG12109-RB 0.011
RASSF8 CG5053 gene product from transcript CG5053-RA 0.011
CG10741 CG10741 gene product from transcript CG10741-RB 0.011
Atg9 Autophagy-specific gene 9 0.011
egr eiger 0.011
CG14937 CG14937 gene product from transcript CG14937-RA 0.011
CG1806 CG1806 gene product from transcript CG1806-RA 0.011
l(1)G0469 lethal (1) G0469 0.011
obst-A obstructor-A 0.011
pyd polychaetoid 0.011
hppy happyhour 0.011
mop myopic 0.011
Tsc1 CG6147 gene product from transcript CG6147-RA 0.010
lmg lemming 0.010
PEK pancreatic eIF-2alpha kinase 0.010
TpnC47D Troponin C at 47D 0.010
Dcr-1 Dicer-1 0.010
Mlp84B Muscle LIM protein at 84B 0.010
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Danio rerio
Name Description Probability Func Analog Organism
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Homo sapiens
Name Description Probability Func Analog Organism
DYRK1A dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A 0.745
YAP1 Yes-associated protein 1 0.593
LATS2 LATS, large tumor suppressor, homolog 2 (Drosophila) 0.107
HIPK2 homeodomain interacting protein kinase 2 0.057
CD44 CD44 molecule (Indian blood group) 0.039
HIPK3 homeodomain interacting protein kinase 3 0.037
RUNX1 runt-related transcription factor 1 0.036
UBE2I ubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast) 0.034
MAP3K1 mitogen-activated protein kinase kinase kinase 1 0.032
ARHGDIA Rho GDP dissociation inhibitor (GDI) alpha 0.031
DCAF7 DDB1 and CUL4 associated factor 7 0.029
AMOTL1 angiomotin like 1 0.028
LATS1 LATS, large tumor suppressor, homolog 1 (Drosophila) 0.025
TBC1D10A TBC1 domain family, member 10A 0.023
SLC9A3R1 solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1 0.023
PTPN14 protein tyrosine phosphatase, non-receptor type 14 0.023
LIMD1 LIM domains containing 1 0.017
PPP1R16A protein phosphatase 1, regulatory (inhibitor) subunit 16A 0.015
AMOTL2 angiomotin like 2 0.015
EP300 E1A binding protein p300 0.015
SCHIP1 schwannomin interacting protein 1 0.015
TOX4 TOX high mobility group box family member 4 0.013
VCL vinculin 0.012
MECP2 methyl CpG binding protein 2 (Rett syndrome) 0.011
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Mus musculus
Name Description Probability Func Analog Organism
Yap1 yes-associated protein 1 0.991
Nf1 neurofibromatosis 1 0.989
Trp53 transformation related protein 53 0.968
Wwtr1 WW domain containing transcription regulator 1 0.965
Fgfr3 fibroblast growth factor receptor 3 0.962
Gli3 GLI-Kruppel family member GLI3 0.888
Fgfr2 fibroblast growth factor receptor 2 0.856
Isl1 ISL1 transcription factor, LIM/homeodomain 0.835
Pax3 paired box gene 3 0.795
Mdm2 transformed mouse 3T3 cell double minute 2 0.737
Apc adenomatosis polyposis coli 0.731
Smad6 MAD homolog 6 (Drosophila) 0.721
Vegfa vascular endothelial growth factor A 0.693
Ptpn11 protein tyrosine phosphatase, non-receptor type 11 0.652
Nanog Nanog homeobox 0.597
Sox2 SRY-box containing gene 2 0.557
Sall4 sal-like 4 (Drosophila) 0.555
Meox2 mesenchyme homeobox 2 0.551
Chd7 chromodomain helicase DNA binding protein 7 0.497
Six1 sine oculis-related homeobox 1 homolog (Drosophila) 0.493
Invs inversin 0.491
Pou5f1 POU domain, class 5, transcription factor 1 0.485
Kitl kit ligand 0.473
Efnb2 ephrin B2 0.472
Shh sonic hedgehog 0.457
Erbb3 v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) 0.428
She src homology 2 domain-containing transforming protein E 0.422
Foxc2 forkhead box C2 0.415
Gata4 GATA binding protein 4 0.413
Sox4 SRY-box containing gene 4 0.411
Tgfb2 transforming growth factor, beta 2 0.405
Bmp4 bone morphogenetic protein 4 0.388
Fgfr1 fibroblast growth factor receptor 1 0.384
Tead1 TEA domain family member 1 0.369
Ptprb protein tyrosine phosphatase, receptor type, B 0.363
Tbx2 T-box 2 0.337
Hspg2 perlecan (heparan sulfate proteoglycan 2) 0.330
Ret ret proto-oncogene 0.324
Epas1 endothelial PAS domain protein 1 0.315
Nfib nuclear factor I/B 0.313
Flt1 FMS-like tyrosine kinase 1 0.307
Tie1 tyrosine kinase with immunoglobulin-like and EGF-like domains 1 0.306
Sox11 SRY-box containing gene 11 0.278
Hes1 hairy and enhancer of split 1 (Drosophila) 0.271
Pax6 paired box gene 6 0.257
Tcfap2a transcription factor AP-2, alpha 0.246
Tsc1 tuberous sclerosis 1 0.243
Fgf8 fibroblast growth factor 8 0.240
Rasip1 Ras interacting protein 1 0.226
Ntf3 neurotrophin 3 0.219
Erbb2 v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) 0.213
Amotl2 angiomotin-like 2 0.213
Bmpr1a bone morphogenetic protein receptor, type 1A 0.204
Flt4 FMS-like tyrosine kinase 4 0.198
Tead2 TEA domain family member 2 0.197
Mycn v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian) 0.196
Kdr kinase insert domain protein receptor 0.195
Sox7 SRY-box containing gene 7 0.187
Edar ectodysplasin-A receptor 0.184
Tsc2 tuberous sclerosis 2 0.176
Foxi3 forkhead box I3 0.171
Sall3 sal-like 3 (Drosophila) 0.170
Cdh5 cadherin 5 0.159
Smad3 MAD homolog 3 (Drosophila) 0.158
Itga3 integrin alpha 3 0.156
Jag1 jagged 1 0.155
Hhex hematopoietically expressed homeobox 0.148
Gata3 GATA binding protein 3 0.148
Sema3f sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F 0.141
Tbx3 T-box 3 0.139
Sox17 SRY-box containing gene 17 0.138
Gata2 GATA binding protein 2 0.137
Sox18 SRY-box containing gene 18 0.137
Ptpn21 protein tyrosine phosphatase, non-receptor type 21 0.137
Eya1 eyes absent 1 homolog (Drosophila) 0.137
Lrp2 low density lipoprotein receptor-related protein 2 0.136
Msx1 homeobox, msh-like 1 0.135
Cldn5 claudin 5 0.132
Smo smoothened homolog (Drosophila) 0.130
Rassf5 Ras association (RalGDS/AF-6) domain family member 5 0.128
Cdc42ep1 CDC42 effector protein (Rho GTPase binding) 1 0.126
Rint1 RAD50 interactor 1 0.125
Hand1 heart and neural crest derivatives expressed transcript 1 0.124
Rb1 retinoblastoma 1 0.124
Rarg retinoic acid receptor, gamma 0.123
Acvr1 activin A receptor, type 1 0.121
Prkar1a protein kinase, cAMP dependent regulatory, type I, alpha 0.119
Itgb1 integrin beta 1 (fibronectin receptor beta) 0.116
Pitx2 paired-like homeodomain transcription factor 2 0.113
Sfn stratifin 0.113
Zfhx3 zinc finger homeobox 3 0.111
Adcy4 adenylate cyclase 4 0.110
Cux1 cut-like homeobox 1 0.109
Myo10 myosin X 0.109
Kif1b kinesin family member 1B 0.108
Tcf7l1 transcription factor 7-like 1 (T-cell specific, HMG box) 0.108
Tinagl1 tubulointerstitial nephritis antigen-like 1 0.107
Fgf10 fibroblast growth factor 10 0.107
Cdkn1a cyclin-dependent kinase inhibitor 1A (P21) 0.103
Efnb1 ephrin B1 0.102
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Rattus norvegicus
Name Description Probability Func Analog Organism
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism