The network for 'cell aggregation' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

cell aggregation

The clustering together and adhesion of initially separate cells to form an aggregate. Examples include the clustering of unicellular organisms or blood cells in suspension and the condensation of mesenchymal cells during cartilage formation.

Homo sapiens
Name Description Probability Func Analog Organism
CDKN2A cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4) 0.998
MAPK3 mitogen-activated protein kinase 3 0.983
PKD2 polycystic kidney disease 2 (autosomal dominant) 0.964
GDF5 growth differentiation factor 5 0.929
DUSP1 dual specificity phosphatase 1 0.838
CYR61 cysteine-rich, angiogenic inducer, 61 0.782
ZFP36L1 zinc finger protein 36, C3H type-like 1 0.682
MAPK1 mitogen-activated protein kinase 1 0.679
FGF18 fibroblast growth factor 18 0.665
FGFR2 fibroblast growth factor receptor 2 0.611
ADAMTS2 ADAM metallopeptidase with thrombospondin type 1 motif, 2 0.456
PTPRR protein tyrosine phosphatase, receptor type, R 0.445
WNT1 wingless-type MMTV integration site family, member 1 0.311
COL2A1 collagen, type II, alpha 1 0.308
DUSP9 dual specificity phosphatase 9 0.246
MED1 mediator complex subunit 1 0.226
FGF1 fibroblast growth factor 1 (acidic) 0.202
FOXF2 forkhead box F2 0.169
WIF1 WNT inhibitory factor 1 0.159
PDGFB platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog) 0.156
BMP2 bone morphogenetic protein 2 0.148
MKNK2 MAP kinase interacting serine/threonine kinase 2 0.147
AQP5 aquaporin 5 0.144
FGF10 fibroblast growth factor 10 0.135
MMP11 matrix metallopeptidase 11 (stromelysin 3) 0.128
SFRP1 secreted frizzled-related protein 1 0.127
FGF4 fibroblast growth factor 4 0.120
BMP4 bone morphogenetic protein 4 0.120
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast) 0.118
MKNK1 MAP kinase interacting serine/threonine kinase 1 0.114
NPHP1 nephronophthisis 1 (juvenile) 0.112
HYAL1 hyaluronoglucosaminidase 1 0.107
MAPK11 mitogen-activated protein kinase 11 0.105
FGF3 fibroblast growth factor 3 0.101
FOXC2 forkhead box C2 (MFH-1, mesenchyme forkhead 1) 0.098
CRLF1 cytokine receptor-like factor 1 0.097
FGFR3 fibroblast growth factor receptor 3 0.089
WNT10A wingless-type MMTV integration site family, member 10A 0.086
DUSP16 dual specificity phosphatase 16 0.081
LBX1 ladybird homeobox 1 0.079
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide) 0.079
FN1 fibronectin 1 0.079
PRPH peripherin 0.079
CACNA1G calcium channel, voltage-dependent, T type, alpha 1G subunit 0.077
HR hairless homolog (mouse) 0.076
WNT11 wingless-type MMTV integration site family, member 11 0.075
IHH Indian hedgehog 0.075
FOXL1 forkhead box L1 0.071
FGF19 fibroblast growth factor 19 0.070
SOX11 SRY (sex determining region Y)-box 11 0.069
NCOA6 nuclear receptor coactivator 6 0.069
COL9A2 collagen, type IX, alpha 2 0.069
EPHB3 EPH receptor B3 0.068
C1QL1 complement component 1, q subcomponent-like 1 0.068
ST8SIA2 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2 0.066
DUSP3 dual specificity phosphatase 3 0.066
NXPH3 neurexophilin 3 0.062
FGF8 fibroblast growth factor 8 (androgen-induced) 0.062
PTPRJ protein tyrosine phosphatase, receptor type, J 0.062
HOXD9 homeobox D9 0.061
ENTPD2 ectonucleoside triphosphate diphosphohydrolase 2 0.060
COL10A1 collagen, type X, alpha 1 0.058
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein 0.058
HSPG2 heparan sulfate proteoglycan 2 0.054
EXOC3L2 exocyst complex component 3-like 2 0.054
PRELP proline/arginine-rich end leucine-rich repeat protein 0.054
CDX1 caudal type homeobox 1 0.053
BMP7 bone morphogenetic protein 7 0.053
BMP8A bone morphogenetic protein 8a 0.053
FOXJ1 forkhead box J1 0.052
GRP gastrin-releasing peptide 0.052
COL1A1 collagen, type I, alpha 1 0.051
MAP2K1 mitogen-activated protein kinase kinase 1 0.050
CUX1 cut-like homeobox 1 0.050
HES2 hairy and enhancer of split 2 (Drosophila) 0.049
WNT7A wingless-type MMTV integration site family, member 7A 0.049
NGFR nerve growth factor receptor 0.049
HOXB1 homeobox B1 0.048
SIX2 SIX homeobox 2 0.048
FEV FEV (ETS oncogene family) 0.048
RPS6KA3 ribosomal protein S6 kinase, 90kDa, polypeptide 3 0.047
SMO smoothened homolog (Drosophila) 0.047
ITGBL1 integrin, beta-like 1 (with EGF-like repeat domains) 0.047
COL11A1 collagen, type XI, alpha 1 0.047
PAX8 paired box 8 0.046
HS3ST6 heparan sulfate (glucosamine) 3-O-sulfotransferase 6 0.046
POU3F1 POU class 3 homeobox 1 0.046
MAPK9 mitogen-activated protein kinase 9 0.046
PXN paxillin 0.045
HOXD13 homeobox D13 0.044
GDF10 growth differentiation factor 10 0.043
CHST3 carbohydrate (chondroitin 6) sulfotransferase 3 0.042
INHBB inhibin, beta B 0.042
GATA1 GATA binding protein 1 (globin transcription factor 1) 0.042
FBLN1 fibulin 1 0.042
PAX1 paired box 1 0.042
NKD2 naked cuticle homolog 2 (Drosophila) 0.042
FZD8 frizzled homolog 8 (Drosophila) 0.042
RAX retina and anterior neural fold homeobox 0.041
HOXD1 homeobox D1 0.041
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Danio rerio
Name Description Probability Func Analog Organism
col2a1a collagen type II, alpha-1a 0.470
myod1 myogenic differentiation 1 0.335
ptch2 patched 2 0.163
gsc goosecoid 0.159
col27a1a collagen, type XXVII, alpha 1a 0.113
pea3 ETS-domain transcription factor pea3 0.083
tgfb3 transforming growth factor, beta 3 0.082
fabp2 fatty acid binding protein 2, intestinal 0.062
col11a2 collagen type XI alpha-2 0.061
loxl3b lysyl oxidase-like 3b 0.059
fn1 fibronectin 1 0.057
nadl1.1 neural adhesion molecule L1.1 0.055
sulf1 sulfatase 1 0.052
trpv1 transient receptor potential cation channel subfamily V member 1 0.052
lect1 leukocyte cell derived chemotaxin 1 0.051
wnt9a wingless-type MMTV integration site family, member 9A 0.050
osr2 odd-skipped related 2 (Drosophila) 0.048
sox10 SRY-box containing gene 10 0.042
myog myogenin 0.041
jam2b junctional adhesion molecule 2b 0.040
gdf6a growth differentiation factor 6a 0.040
snai1a snail homolog 1a (Drosophila) 0.037
col1a2 collagen, type I, alpha 2 0.037
col10a1 collagen, type X, alpha 1 0.036
hapln1a hyaluronan and proteoglycan link protein 1a 0.036
jam2a junctional adhesion molecule 2a 0.036
sdprb serum deprivation response b 0.035
fgf8a fibroblast growth factor 8 a 0.035
dspa desmoplakin a 0.035
barx1 BarH-like homeobox 1 0.035
utx ubiquitously transcribed tetratricopeptide repeat, X chromosome 0.034
itga5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide) 0.034
dsg2 desmoglein 2 0.033
foxa3 forkhead box A3 0.032
tcf21 transcription factor 21 0.031
bmp4 bone morphogenetic protein 4 0.029
cast calpastatin 0.029
zgc:92429 zgc:92429 0.029
cart1 cartilage paired-class homeoprotein 1 0.029
slc6a6 solute carrier family 6 (neurotransmitter transporter, taurine), member 6 0.028
hand2 heart and neural crest derivatives expressed transcript 2 0.027
npnt nephronectin 0.027
mych myelocytomatosis oncogene homolog 0.027
ptch1 patched 1 0.027
aldh1a2 aldehyde dehydrogenase 1 family, member A2 0.026
snai2 snail homolog 2 (Drosophila) 0.026
atp1a1a.4 ATPase, Na+/K+ transporting, alpha 1a.4 polypeptide 0.025
dab2 disabled homolog 2 (Drosophila) 0.023
slc4a2a solute carrier family 4, anion exchanger, member 2a 0.023
lmo4a LIM domain only 4a 0.023
epyc epiphycan 0.023
twist2 twist2 0.023
lbx2 ladybird homeobox homolog 2 (Drosophila) 0.022
trpv4 transient receptor potential cation channel, subfamily V, member 4 0.021
shha sonic hedgehog a 0.021
myf5 myogenic factor 5 0.020
actc1b actin, alpha, cardiac muscle 1b 0.020
osr1 odd-skipped related 1 (Drosophila) 0.020
efemp2 EGF-containing fibulin-like extracellular matrix protein 2 0.020
zgc:85866 zgc:85866 0.019
sema3ab semaphorin 3ab 0.019
bmper BMP binding endothelial regulator 0.019
LOC556647 GDNF family receptor alpha-4-like 0.019
pdzrn3 PDZ domain containing RING finger 3 and PDZ domain containing ring finger 3 0.019
meox1 mesenchyme homeobox 1 0.018
crb2a crumbs homolog 2a 0.018
slc3a2 solute carrier family 3, member 2 0.018
rapsn receptor-associated protein of the synapse, 43kD 0.018
p2rx2 purinergic receptor P2X, ligand-gated ion channel, 2 0.018
igf2a insulin-like growth factor 2a 0.018
col11a1b collagen type XI alpha-1b and collagen, type XI, alpha 1b 0.017
nrp1b neuropilin 1b 0.017
apex2 APEX nuclease (apurinic/apyrimidinic endonuclease) 2 0.017
dlc deltaC 0.016
gcga glucagon a and glucagon a-like 0.016
col27a1b collagen, type XXVII, alpha 1b 0.016
notch2 notch homolog 2 0.016
esr1 estrogen receptor 1 0.016
si:ch211-9d9.3 si:ch211-9d9.3 0.016
bmp3 bone morphogenetic protein 3 0.016
zgc:85838 zgc:85838 0.016
ftr82 finTRIM family, member 82 0.016
mkxa mohawk homeobox a 0.016
tfeb transcription factor EB 0.016
dusp6 dual specificity phosphatase 6 0.016
si:dkey-261h17.1 si:dkey-261h17.1 0.016
plod1a procollagen-lysine 1, 2-oxoglutarate 5-dioxygenase 1a 0.015
hoxc8a homeo box C8a 0.015
acana aggrecan a 0.015
lepr leptin receptor 0.015
crip2 cysteine-rich protein 2 0.015
wls wntless homolog (Drosophila) 0.015
prdm16 PR domain containing 16 0.014
nrf1 nuclear respiratory factor 1 0.014
pthlh parathyroid hormone-like hormone 0.014
fzd2 frizzled homolog 2 0.014
rasl11b RAS-like, family 11, member B 0.014
or111-1 odorant receptor, family D, subfamily 111, member 1 0.014
mc5rb melanocortin 5b receptor 0.014
adam23a a disintegrin and metallopeptidase domain 23a 0.014
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Drosophila melanogaster
Name Description Probability Func Analog Organism
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Mus musculus
Name Description Probability Func Analog Organism
Tgfb2 transforming growth factor, beta 2 0.991
Pax3 paired box gene 3 0.984
Col1a1 collagen, type I, alpha 1 0.982
Meox2 mesenchyme homeobox 2 0.981
Fbn1 fibrillin 1 0.944
Tgfbr2 transforming growth factor, beta receptor II 0.895
Trp53 transformation related protein 53 0.887
Pkd1 polycystic kidney disease 1 homolog 0.884
Pten phosphatase and tensin homolog 0.821
Fgf10 fibroblast growth factor 10 0.776
Gli2 GLI-Kruppel family member GLI2 0.702
Pax7 paired box gene 7 0.700
Mapk14 mitogen-activated protein kinase 14 0.698
Gli3 GLI-Kruppel family member GLI3 0.682
Shh sonic hedgehog 0.662
Pitx2 paired-like homeodomain transcription factor 2 0.637
Foxc1 forkhead box C1 0.625
Lox lysyl oxidase 0.484
Eng endoglin 0.481
Sox9 SRY-box containing gene 9 0.458
Fgfr3 fibroblast growth factor receptor 3 0.449
Rarg retinoic acid receptor, gamma 0.411
Twist2 twist homolog 2 (Drosophila) 0.386
Col6a3 collagen, type VI, alpha 3 0.382
Rara retinoic acid receptor, alpha 0.376
Gata4 GATA binding protein 4 0.340
Prrx1 paired related homeobox 1 0.332
Bmp4 bone morphogenetic protein 4 0.327
Hspg2 perlecan (heparan sulfate proteoglycan 2) 0.310
Pax2 paired box gene 2 0.310
Fgf8 fibroblast growth factor 8 0.297
Nf1 neurofibromatosis 1 0.295
Pthlh parathyroid hormone-like peptide 0.276
Six1 sine oculis-related homeobox 1 homolog (Drosophila) 0.263
Acvr1 activin A receptor, type 1 0.252
Rarb retinoic acid receptor, beta 0.236
Pax6 paired box gene 6 0.229
Rxra retinoid X receptor alpha 0.220
Tbx1 T-box 1 0.216
Bmpr1a bone morphogenetic protein receptor, type 1A 0.212
Fgfr2 fibroblast growth factor receptor 2 0.207
Ptpn11 protein tyrosine phosphatase, non-receptor type 11 0.201
Sox11 SRY-box containing gene 11 0.195
Smad3 MAD homolog 3 (Drosophila) 0.179
Prrx2 paired related homeobox 2 0.177
Hoxd13 homeobox D13 0.172
Col6a2 collagen, type VI, alpha 2 0.165
Hhex hematopoietically expressed homeobox 0.143
Col11a1 collagen, type XI, alpha 1 0.143
Zeb1 zinc finger E-box binding homeobox 1 0.143
Isl1 ISL1 transcription factor, LIM/homeodomain 0.137
Atoh7 atonal homolog 7 (Drosophila) 0.129
Nodal nodal 0.127
Twist1 twist homolog 1 (Drosophila) 0.123
Ntf3 neurotrophin 3 0.121
Col6a1 collagen, type VI, alpha 1 0.118
Fst follistatin 0.115
Capn6 calpain 6 0.113
Gdf11 growth differentiation factor 11 0.112
Bdnf brain derived neurotrophic factor 0.112
Ptx3 pentraxin related gene 0.111
Egfr epidermal growth factor receptor 0.106
Ror2 receptor tyrosine kinase-like orphan receptor 2 0.106
Sox4 SRY-box containing gene 4 0.105
Lmx1a LIM homeobox transcription factor 1 alpha 0.104
Zfpm2 zinc finger protein, multitype 2 0.101
Pdgfra platelet derived growth factor receptor, alpha polypeptide 0.095
Btbd17 BTB (POZ) domain containing 17 0.092
Tgfbr1 transforming growth factor, beta receptor I 0.090
Col5a1 collagen, type V, alpha 1 0.089
Tll1 tolloid-like 0.086
Foxc2 forkhead box C2 0.084
Tbx10 T-box 10 0.082
Nr3c1 nuclear receptor subfamily 3, group C, member 1 0.081
Acan aggrecan 0.079
Sox17 SRY-box containing gene 17 0.076
Thbs1 thrombospondin 1 0.068
Eln elastin 0.068
Bcl6b B-cell CLL/lymphoma 6, member B 0.067
Pou3f3 POU domain, class 3, transcription factor 3 0.067
Fstl1 follistatin-like 1 0.066
Robo3 roundabout homolog 3 (Drosophila) 0.065
Vegfa vascular endothelial growth factor A 0.065
Mmp14 matrix metallopeptidase 14 (membrane-inserted) 0.064
Tnc tenascin C 0.064
Mycn v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian) 0.060
Ednra endothelin receptor type A 0.060
Hapln1 hyaluronan and proteoglycan link protein 1 0.059
Creb1 cAMP responsive element binding protein 1 0.057
Kit kit oncogene 0.057
Tbx15 T-box 15 0.055
Gal galanin 0.055
Col8a1 collagen, type VIII, alpha 1 0.055
Thrb thyroid hormone receptor beta 0.055
Nos3 nitric oxide synthase 3, endothelial cell 0.053
Tef thyrotroph embryonic factor 0.052
Meox1 mesenchyme homeobox 1 0.051
Dhh desert hedgehog 0.049
Col2a1 collagen, type II, alpha 1 0.048
Csf1 colony stimulating factor 1 (macrophage) 0.047
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Rattus norvegicus
Name Description Probability Func Analog Organism
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism
FLO10 Flo10p 0.981
FIG2 Fig2p 0.875
MUC1 Muc1p 0.713
FLO9 Flo9p 0.668
FLO5 Flo5p 0.605
FLO1 Flo1p 0.384
CWP2 Cwp2p 0.267
MSS11 Mss11p 0.255
FLO8 Flo8p 0.244
SFL1 Sfl1p 0.091
AGA1 Aga1p 0.059
FIG1 Fig1p 0.045
AGA2 Aga2p 0.041
YKR104W hypothetical protein 0.033
SCW4 Scw4p 0.030
YLR264C-A hypothetical protein 0.029
SAG1 Sag1p 0.027
SRD1 Srd1p 0.026
TEC1 Tec1p 0.026
YOL038C-A hypothetical protein 0.022
LEU2 Leu2p 0.022
CUP1-1 Cup1-1p 0.021
YLR162W hypothetical protein 0.021
ARP10 Arp10p 0.020
ZPS1 Zps1p 0.020
YLR040C hypothetical protein 0.020
SPL2 Spl2p 0.019
HXT3 Hxt3p 0.018
MER1 Mer1p 0.018
PHD1 Phd1p 0.018
YLR042C hypothetical protein 0.018
TPI1 Tpi1p 0.017
YPR157W hypothetical protein 0.017
ATP6 Atp6p 0.017
YMR317W hypothetical protein 0.016
YBR013C hypothetical protein 0.016
ARG8 Arg8p 0.015
YAL064W hypothetical protein 0.015
AUA1 Aua1p 0.015
FKS3 Fks3p 0.014
HPF1 Hpf1p 0.014
FMT1 Fmt1p 0.014
MF(ALPHA)2 Mf(alpha)2p 0.014
OPT2 Opt2p 0.013
BSC1 Bsc1p 0.013
CPD1 Cpd1p 0.013
YAL037C-A hypothetical protein 0.013
YOL013W-A hypothetical protein 0.013
SWC7 Swc7p 0.013
IZH4 Izh4p 0.013
YIL151C hypothetical protein 0.013
PTR2 Ptr2p 0.013
BDS1 Bds1p 0.012
SKS1 Sks1p 0.012
YAR068W hypothetical protein 0.012
TIR3 Tir3p 0.012
MFA2 Mfa2p 0.012
IMA5 Ima5p 0.012
MFA1 Mfa1p 0.012
YPL067C hypothetical protein 0.012
DIC1 Dic1p 0.012
SCM4 Scm4p 0.011
ADH2 Adh2p 0.011
UPS3 Ups3p 0.011
YIR035C hypothetical protein 0.011
DUR1,2 Dur1,2p 0.011
YPR096C hypothetical protein 0.011
TDH3 Tdh3p 0.011
RNP1 Rnp1p 0.011
YGL006W-A hypothetical protein 0.011
CRP1 Crp1p 0.011
YAL065C hypothetical protein 0.011
YNL033W hypothetical protein 0.010
YAR066W hypothetical protein 0.010
YIR042C hypothetical protein 0.010
NFT1 Nft1p 0.010
YKR075C hypothetical protein 0.010
YJL107C hypothetical protein 0.010
YDR034C-A hypothetical protein 0.010
CHA1 Cha1p 0.010
YBL029W hypothetical protein 0.010