IMP
Process View
The network for 'interleukin 8 mediated signaling pathway' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.
Multiple Organisms
interleukin 8 mediated signaling pathway
A series of molecular signals initiated by the binding of interleukin-8 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| CCL5 | chemokine (C-C motif) ligand 5 | 1.000 | |
| CCR2 | chemokine (C-C motif) receptor 2 | 1.000 | |
| CCR5 | chemokine (C-C motif) receptor 5 | 0.998 | |
| IL2RB | interleukin 2 receptor, beta | 0.992 | |
| CCL22 | chemokine (C-C motif) ligand 22 | 0.967 | |
| CXCL9 | chemokine (C-X-C motif) ligand 9 | 0.935 | |
| IRF4 | interferon regulatory factor 4 | 0.926 | |
| IFNG | interferon, gamma | 0.914 | |
| CCR4 | chemokine (C-C motif) receptor 4 | 0.911 | |
| CD74 | CD74 molecule, major histocompatibility complex, class II invariant chain | 0.862 | |
| CXCR3 | chemokine (C-X-C motif) receptor 3 | 0.832 | |
| CCR7 | chemokine (C-C motif) receptor 7 | 0.831 | |
| CD40LG | CD40 ligand | 0.733 | |
| IL16 | interleukin 16 (lymphocyte chemoattractant factor) | 0.617 | |
| CCL4 | chemokine (C-C motif) ligand 4 | 0.608 | |
| CXCR6 | chemokine (C-X-C motif) receptor 6 | 0.554 | |
| SLAMF7 | SLAM family member 7 | 0.552 | |
| LTA | lymphotoxin alpha (TNF superfamily, member 1) | 0.525 | |
| CCR1 | chemokine (C-C motif) receptor 1 | 0.505 | |
| IL10 | interleukin 10 | 0.435 | |
| IL10RA | interleukin 10 receptor, alpha | 0.397 | |
| LAIR1 | leukocyte-associated immunoglobulin-like receptor 1 | 0.342 | |
| CD86 | CD86 molecule | 0.310 | |
| CCL3 | chemokine (C-C motif) ligand 3 | 0.293 | |
| TNFSF8 | tumor necrosis factor (ligand) superfamily, member 8 | 0.278 | |
| CXCL13 | chemokine (C-X-C motif) ligand 13 | 0.273 | |
| CXCL11 | chemokine (C-X-C motif) ligand 11 | 0.218 | |
| CXCR5 | chemokine (C-X-C motif) receptor 5 | 0.215 | |
| CLEC7A | C-type lectin domain family 7, member A | 0.187 | |
| CXCL10 | chemokine (C-X-C motif) ligand 10 | 0.182 | |
| CCR6 | chemokine (C-C motif) receptor 6 | 0.157 | |
| IL1R2 | interleukin 1 receptor, type II | 0.150 | |
| LAG3 | lymphocyte-activation gene 3 | 0.146 | |
| CCL7 | chemokine (C-C motif) ligand 7 | 0.139 | |
| CCL19 | chemokine (C-C motif) ligand 19 | 0.129 | |
| CCL11 | chemokine (C-C motif) ligand 11 | 0.121 | |
| KLRD1 | killer cell lectin-like receptor subfamily D, member 1 | 0.103 | |
| TNFRSF9 | tumor necrosis factor receptor superfamily, member 9 | 0.098 | |
| GZMK | granzyme K (granzyme 3; tryptase II) | 0.098 | |
| CLEC4A | C-type lectin domain family 4, member A | 0.095 | |
| IL21R | interleukin 21 receptor | 0.093 | |
| CD2 | CD2 molecule | 0.087 | |
| IL2RG | interleukin 2 receptor, gamma | 0.086 | |
| TNF | tumor necrosis factor | 0.085 | |
| CD1C | CD1c molecule | 0.085 | |
| SPIB | Spi-B transcription factor (Spi-1/PU.1 related) | 0.085 | |
| CCL8 | chemokine (C-C motif) ligand 8 | 0.084 | |
| PRAF2 | PRA1 domain family, member 2 | 0.082 | |
| HLA-DQA1 | major histocompatibility complex, class II, DQ alpha 1 | 0.082 | |
| LGALS2 | lectin, galactoside-binding, soluble, 2 | 0.078 | |
| FASLG | Fas ligand (TNF superfamily, member 6) | 0.075 | |
| CD80 | CD80 molecule | 0.074 | |
| CYBB | cytochrome b-245, beta polypeptide | 0.074 | |
| P2RY10 | purinergic receptor P2Y, G-protein coupled, 10 | 0.073 | |
| CCR3 | chemokine (C-C motif) receptor 3 | 0.072 | |
| CD22 | CD22 molecule | 0.066 | |
| LTB | lymphotoxin beta (TNF superfamily, member 3) | 0.065 | |
| IL2RA | interleukin 2 receptor, alpha | 0.057 | |
| FCER2 | Fc fragment of IgE, low affinity II, receptor for (CD23) | 0.055 | |
| IL18RAP | interleukin 18 receptor accessory protein | 0.054 | |
| TLR2 | toll-like receptor 2 | 0.051 | |
| CXCR2 | chemokine (C-X-C motif) receptor 2 | 0.051 | |
| DPP4 | dipeptidyl-peptidase 4 | 0.050 | |
| GNAI2 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 | 0.048 | |
| CLEC4E | C-type lectin domain family 4, member E | 0.047 | |
| CCL18 | chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated) | 0.046 | |
| CD79A | CD79a molecule, immunoglobulin-associated alpha | 0.044 | |
| FCGR3B | Fc fragment of IgG, low affinity IIIb, receptor (CD16b) | 0.043 | |
| FGL2 | fibrinogen-like 2 | 0.041 | |
| CD28 | CD28 molecule | 0.040 | |
| IGSF6 | immunoglobulin superfamily, member 6 | 0.040 | |
| FCN1 | ficolin (collagen/fibrinogen domain containing) 1 | 0.039 | |
| RNASE2 | ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin) | 0.039 | |
| EVI2B | ecotropic viral integration site 2B | 0.037 | |
| CSF2RA | colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage) | 0.037 | |
| CD48 | CD48 molecule | 0.036 | |
| GNAO1 | guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O | 0.035 | |
| CCR8 | chemokine (C-C motif) receptor 8 | 0.034 | |
| AQP9 | aquaporin 9 | 0.034 | |
| IL4 | interleukin 4 | 0.033 | |
| EMR1 | egf-like module containing, mucin-like, hormone receptor-like 1 | 0.033 | |
| ADAMDEC1 | ADAM-like, decysin 1 | 0.033 | |
| IL1RN | interleukin 1 receptor antagonist | 0.032 | |
| ITK | IL2-inducible T-cell kinase | 0.032 | |
| CD93 | CD93 molecule | 0.032 | |
| RGS1 | regulator of G-protein signaling 1 | 0.032 | |
| CLEC5A | C-type lectin domain family 5, member A | 0.031 | |
| CTLA4 | cytotoxic T-lymphocyte-associated protein 4 | 0.031 | |
| SPOCK2 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2 | 0.031 | |
| CD19 | CD19 molecule | 0.030 | |
| GPR18 | G protein-coupled receptor 18 | 0.030 | |
| CD3E | CD3e molecule, epsilon (CD3-TCR complex) | 0.030 | |
| BIN2 | bridging integrator 2 | 0.029 | |
| CCL20 | chemokine (C-C motif) ligand 20 | 0.028 | |
| ITGAM | integrin, alpha M (complement component 3 receptor 3 subunit) | 0.028 | |
| IL1B | interleukin 1, beta | 0.027 | |
| SASH3 | SAM and SH3 domain containing 3 | 0.027 | |
| LAX1 | lymphocyte transmembrane adaptor 1 | 0.027 | |
| CCL13 | chemokine (C-C motif) ligand 13 | 0.026 | |
| MS4A6A | membrane-spanning 4-domains, subfamily A, member 6A | 0.026 |
