Process View
The network for 'chemokine c c motif ligand 19 signaling pathway' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.
A series of molecular signals initiated by the binding of the C-C chemokine CCL19 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| CCL5 | chemokine (C-C motif) ligand 5 | 1.000 | |
| CCR5 | chemokine (C-C motif) receptor 5 | 1.000 | |
| IL2RB | interleukin 2 receptor, beta | 0.995 | |
| IFNG | interferon, gamma | 0.990 | |
| CXCR6 | chemokine (C-X-C motif) receptor 6 | 0.986 | |
| CCR2 | chemokine (C-C motif) receptor 2 | 0.975 | |
| CD40LG | CD40 ligand | 0.933 | |
| CXCL9 | chemokine (C-X-C motif) ligand 9 | 0.924 | |
| CCL22 | chemokine (C-C motif) ligand 22 | 0.903 | |
| CCL4 | chemokine (C-C motif) ligand 4 | 0.899 | |
| IRF4 | interferon regulatory factor 4 | 0.893 | |
| CCR7 | chemokine (C-C motif) receptor 7 | 0.798 | |
| CD2 | CD2 molecule | 0.743 | |
| SLAMF7 | SLAM family member 7 | 0.696 | |
| CXCR3 | chemokine (C-X-C motif) receptor 3 | 0.659 | |
| CD74 | CD74 molecule, major histocompatibility complex, class II invariant chain | 0.655 | |
| IL16 | interleukin 16 (lymphocyte chemoattractant factor) | 0.548 | |
| IL10RA | interleukin 10 receptor, alpha | 0.500 | |
| CCR4 | chemokine (C-C motif) receptor 4 | 0.488 | |
| CXCR4 | chemokine (C-X-C motif) receptor 4 | 0.467 | |
| GZMK | granzyme K (granzyme 3; tryptase II) | 0.447 | |
| ITK | IL2-inducible T-cell kinase | 0.394 | |
| IL10 | interleukin 10 | 0.367 | |
| LTA | lymphotoxin alpha (TNF superfamily, member 1) | 0.360 | |
| CLEC7A | C-type lectin domain family 7, member A | 0.356 | |
| GPR171 | G protein-coupled receptor 171 | 0.338 | |
| HLA-DPA1 | major histocompatibility complex, class II, DP alpha 1 | 0.333 | |
| KLRD1 | killer cell lectin-like receptor subfamily D, member 1 | 0.328 | |
| CXCL13 | chemokine (C-X-C motif) ligand 13 | 0.268 | |
| FASLG | Fas ligand (TNF superfamily, member 6) | 0.267 | |
| TNFSF8 | tumor necrosis factor (ligand) superfamily, member 8 | 0.256 | |
| CXCL11 | chemokine (C-X-C motif) ligand 11 | 0.247 | |
| CD48 | CD48 molecule | 0.227 | |
| IL2RG | interleukin 2 receptor, gamma | 0.217 | |
| CCL3 | chemokine (C-C motif) ligand 3 | 0.202 | |
| CXCL10 | chemokine (C-X-C motif) ligand 10 | 0.192 | |
| IL18RAP | interleukin 18 receptor accessory protein | 0.168 | |
| CCR6 | chemokine (C-C motif) receptor 6 | 0.154 | |
| SIT1 | signaling threshold regulating transmembrane adaptor 1 | 0.149 | |
| CCR8 | chemokine (C-C motif) receptor 8 | 0.143 | |
| CCR9 | chemokine (C-C motif) receptor 9 | 0.141 | |
| IL21R | interleukin 21 receptor | 0.130 | |
| KLRB1 | killer cell lectin-like receptor subfamily B, member 1 | 0.125 | |
| CCL19 | chemokine (C-C motif) ligand 19 | 0.121 | |
| CD3G | CD3g molecule, gamma (CD3-TCR complex) | 0.118 | |
| GPR18 | G protein-coupled receptor 18 | 0.117 | |
| LTB | lymphotoxin beta (TNF superfamily, member 3) | 0.106 | |
| LAIR1 | leukocyte-associated immunoglobulin-like receptor 1 | 0.104 | |
| SLAMF1 | signaling lymphocytic activation molecule family member 1 | 0.104 | |
| CCL11 | chemokine (C-C motif) ligand 11 | 0.103 | |
| CCL8 | chemokine (C-C motif) ligand 8 | 0.094 | |
| CD3E | CD3e molecule, epsilon (CD3-TCR complex) | 0.088 | |
| CCL7 | chemokine (C-C motif) ligand 7 | 0.086 | |
| SELL | selectin L | 0.084 | |
| GIMAP4 | GTPase, IMAP family member 4 | 0.078 | |
| CD83 | CD83 molecule | 0.067 | |
| PRF1 | perforin 1 (pore forming protein) | 0.065 | |
| LAG3 | lymphocyte-activation gene 3 | 0.064 | |
| P2RY10 | purinergic receptor P2Y, G-protein coupled, 10 | 0.062 | |
| IL7R | interleukin 7 receptor | 0.062 | |
| IL4 | interleukin 4 | 0.060 | |
| IL1F5 | interleukin 1 family, member 5 (delta) | 0.058 | |
| KLRK1 | killer cell lectin-like receptor subfamily K, member 1 | 0.058 | |
| CD8A | CD8a molecule | 0.055 | |
| RUNX3 | runt-related transcription factor 3 | 0.055 | |
| CXCR2 | chemokine (C-X-C motif) receptor 2 | 0.055 | |
| CD160 | CD160 molecule | 0.054 | |
| IL2RA | interleukin 2 receptor, alpha | 0.054 | |
| TNFRSF9 | tumor necrosis factor receptor superfamily, member 9 | 0.053 | |
| LGALS2 | lectin, galactoside-binding, soluble, 2 | 0.052 | |
| PVRIG | poliovirus receptor related immunoglobulin domain containing | 0.052 | |
| GZMA | granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3) | 0.051 | |
| GZMH | granzyme H (cathepsin G-like 2, protein h-CCPX) | 0.048 | |
| CXCR5 | chemokine (C-X-C motif) receptor 5 | 0.048 | |
| CD28 | CD28 molecule | 0.044 | |
| DPP4 | dipeptidyl-peptidase 4 | 0.044 | |
| CCR3 | chemokine (C-C motif) receptor 3 | 0.043 | |
| GZMB | granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) | 0.043 | |
| IL1B | interleukin 1, beta | 0.040 | |
| TBX21 | T-box 21 | 0.039 | |
| RGS1 | regulator of G-protein signaling 1 | 0.039 | |
| CYBB | cytochrome b-245, beta polypeptide | 0.038 | |
| TNF | tumor necrosis factor | 0.038 | |
| SPOCK2 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2 | 0.037 | |
| CCL20 | chemokine (C-C motif) ligand 20 | 0.037 | |
| TRAT1 | T cell receptor associated transmembrane adaptor 1 | 0.035 | |
| SLAMF6 | SLAM family member 6 | 0.034 | |
| NKG7 | natural killer cell group 7 sequence | 0.034 | |
| TCL1A | T-cell leukemia/lymphoma 1A | 0.034 | |
| CCR1 | chemokine (C-C motif) receptor 1 | 0.033 | |
| CD3D | CD3d molecule, delta (CD3-TCR complex) | 0.033 | |
| CD226 | CD226 molecule | 0.033 | |
| CD86 | CD86 molecule | 0.033 | |
| FCER2 | Fc fragment of IgE, low affinity II, receptor for (CD23) | 0.032 | |
| HLA-DQA1 | major histocompatibility complex, class II, DQ alpha 1 | 0.032 | |
| UBASH3A | ubiquitin associated and SH3 domain containing A | 0.032 | |
| CD69 | CD69 molecule | 0.032 | |
| HLA-DOA | major histocompatibility complex, class II, DO alpha | 0.031 | |
| CLEC4E | C-type lectin domain family 4, member E | 0.031 | |
| TRAF3IP3 | TRAF3 interacting protein 3 | 0.031 |