IMP
Process View
The network for 'negative regulation of interleukin 2 secretion' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.
Multiple Organisms
negative regulation of interleukin 2 secretion
Any process that stops, prevents or reduces the frequency, rate or extent of interleukin-2 secretion.
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| RIPK1 | receptor (TNFRSF)-interacting serine-threonine kinase 1 | 0.898 | |
| MED15 | mediator complex subunit 15 | 0.896 | |
| UBE2D4 | ubiquitin-conjugating enzyme E2D 4 (putative) | 0.787 | |
| ZNF263 | zinc finger protein 263 | 0.716 | |
| TRIM39 | tripartite motif containing 39 | 0.524 | |
| RBCK1 | RanBP-type and C3HC4-type zinc finger containing 1 | 0.297 | |
| TRIM5 | tripartite motif containing 5 | 0.240 | |
| ZNF473 | zinc finger protein 473 | 0.240 | |
| TRIM21 | tripartite motif containing 21 | 0.173 | |
| TRIM26 | tripartite motif containing 26 | 0.144 | |
| TRIM17 | tripartite motif containing 17 | 0.109 | |
| MCOLN1 | mucolipin 1 | 0.103 | |
| UBE2U | ubiquitin-conjugating enzyme E2U (putative) | 0.100 | |
| TRIM8 | tripartite motif containing 8 | 0.089 | |
| TRIM32 | tripartite motif containing 32 | 0.078 | |
| TRIM41 | tripartite motif containing 41 | 0.075 | |
| TRIM34 | tripartite motif containing 34 | 0.075 | |
| TRIM52 | tripartite motif containing 52 | 0.065 | |
| SP110 | SP110 nuclear body protein | 0.059 | |
| SP100 | SP100 nuclear antigen | 0.046 | |
| OAS2 | 2'-5'-oligoadenylate synthetase 2, 69/71kDa | 0.038 | |
| PHF11 | PHD finger protein 11 | 0.038 | |
| ARIH2 | ariadne homolog 2 (Drosophila) | 0.035 | |
| TRIM35 | tripartite motif containing 35 | 0.035 | |
| PLCD4 | phospholipase C, delta 4 | 0.031 | |
| MYD88 | myeloid differentiation primary response gene (88) | 0.029 | |
| MKRN3 | makorin ring finger protein 3 | 0.029 | |
| TRIM6-TRIM34 | TRIM6-TRIM34 readthrough | 0.027 | |
| USP4 | ubiquitin specific peptidase 4 (proto-oncogene) | 0.027 | |
| RHAG | Rh-associated glycoprotein | 0.024 | |
| PIK3C2B | phosphoinositide-3-kinase, class 2, beta polypeptide | 0.023 | |
| IRF2 | interferon regulatory factor 2 | 0.023 | |
| TRIM4 | tripartite motif containing 4 | 0.023 | |
| UBE2Z | ubiquitin-conjugating enzyme E2Z | 0.023 | |
| MR1 | major histocompatibility complex, class I-related | 0.023 | |
| IRF9 | interferon regulatory factor 9 | 0.022 | |
| TRANK1 | tetratricopeptide repeat and ankyrin repeat containing 1 | 0.021 | |
| RNF5 | ring finger protein 5 | 0.021 | |
| CTSO | cathepsin O | 0.020 | |
| TRIM22 | tripartite motif containing 22 | 0.020 | |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.019 | |
| TAP1 | transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) | 0.018 | |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | 0.018 | |
| TRIM25 | tripartite motif containing 25 | 0.018 | |
| NMI | N-myc (and STAT) interactor | 0.018 | |
| ZNF202 | zinc finger protein 202 | 0.018 | |
| MAGEA1 | melanoma antigen family A, 1 (directs expression of antigen MZ2-E) | 0.017 | |
| XIAP | X-linked inhibitor of apoptosis | 0.015 | |
| RNF114 | ring finger protein 114 | 0.015 | |
| SPTB | spectrin, beta, erythrocytic | 0.015 | |
| BFAR | bifunctional apoptosis regulator | 0.015 | |
| TRIM43 | tripartite motif containing 43 | 0.014 | |
| UBE2L6 | ubiquitin-conjugating enzyme E2L 6 | 0.013 | |
| PRKCA | protein kinase C, alpha | 0.013 | |
| BTN3A3 | butyrophilin, subfamily 3, member A3 | 0.012 | |
| MEX3B | mex-3 homolog B (C. elegans) | 0.012 | |
| RNASEL | ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent) | 0.012 | |
| GYPE | glycophorin E (MNS blood group) | 0.011 | |
| RNF31 | ring finger protein 31 | 0.011 | |
| OSBP2 | oxysterol binding protein 2 | 0.011 | |
| GPR116 | G protein-coupled receptor 116 | 0.011 | |
| FADD | Fas (TNFRSF6)-associated via death domain | 0.011 | |
| SDPR | serum deprivation response | 0.010 | |
| STAT2 | signal transducer and activator of transcription 2, 113kDa | 0.010 | |
| RNF166 | ring finger protein 166 | 0.010 | |
| LRSAM1 | leucine rich repeat and sterile alpha motif containing 1 | 0.010 |
