IMP
Process View
The network for 'negative regulation of immature t cell proliferation' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.
Multiple Organisms
negative regulation of immature t cell proliferation
Any process that stops, prevents, or reduces the frequency, rate or extent of immature T cell proliferation.
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| EGFR | epidermal growth factor receptor | 0.993 | |
| ERBB3 | v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) | 0.971 | |
| BMPR1A | bone morphogenetic protein receptor, type IA | 0.091 | |
| GRB7 | growth factor receptor-bound protein 7 | 0.074 | |
| PIK3R2 | phosphoinositide-3-kinase, regulatory subunit 2 (beta) | 0.043 | |
| SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 | 0.016 | |
| FSTL1 | follistatin-like 1 | 0.014 | |
| ERBB4 | v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian) | 0.013 | |
| VAV3 | vav 3 guanine nucleotide exchange factor | 0.011 | |
| GAB2 | GRB2-associated binding protein 2 | 0.011 | |
| GAB1 | GRB2-associated binding protein 1 | 0.011 | |
| VAV2 | vav 2 guanine nucleotide exchange factor | 0.011 | |
| ABL1 | c-abl oncogene 1, non-receptor tyrosine kinase | 0.011 |
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Mus musculus
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| Fgfr2 | fibroblast growth factor receptor 2 | 1.000 | |
| Shh | sonic hedgehog | 1.000 | |
| Gli3 | GLI-Kruppel family member GLI3 | 0.999 | |
| Foxc1 | forkhead box C1 | 0.999 | |
| Sox9 | SRY-box containing gene 9 | 0.998 | |
| Ptpn11 | protein tyrosine phosphatase, non-receptor type 11 | 0.994 | |
| Ctnnb1 | catenin (cadherin associated protein), beta 1 | 0.991 | |
| Trp53 | transformation related protein 53 | 0.973 | |
| Pten | phosphatase and tensin homolog | 0.966 | |
| Bmp4 | bone morphogenetic protein 4 | 0.962 | |
| Pax3 | paired box gene 3 | 0.938 | |
| Erbb2 | v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) | 0.936 | |
| Itgb1 | integrin beta 1 (fibronectin receptor beta) | 0.933 | |
| Tgfb2 | transforming growth factor, beta 2 | 0.932 | |
| Ret | ret proto-oncogene | 0.921 | |
| Pitx2 | paired-like homeodomain transcription factor 2 | 0.891 | |
| Fgf8 | fibroblast growth factor 8 | 0.862 | |
| Tcfap2a | transcription factor AP-2, alpha | 0.862 | |
| Pdgfra | platelet derived growth factor receptor, alpha polypeptide | 0.790 | |
| Smo | smoothened homolog (Drosophila) | 0.788 | |
| Foxc2 | forkhead box C2 | 0.777 | |
| Fgfr3 | fibroblast growth factor receptor 3 | 0.773 | |
| Col1a1 | collagen, type I, alpha 1 | 0.749 | |
| Rxra | retinoid X receptor alpha | 0.747 | |
| Isl1 | ISL1 transcription factor, LIM/homeodomain | 0.732 | |
| Meox2 | mesenchyme homeobox 2 | 0.677 | |
| Vegfa | vascular endothelial growth factor A | 0.668 | |
| Nf1 | neurofibromatosis 1 | 0.653 | |
| Ntf3 | neurotrophin 3 | 0.617 | |
| Runx2 | runt related transcription factor 2 | 0.589 | |
| Apc | adenomatosis polyposis coli | 0.571 | |
| Kras | v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog | 0.559 | |
| Six1 | sine oculis-related homeobox 1 homolog (Drosophila) | 0.557 | |
| Nkx2-5 | NK2 transcription factor related, locus 5 (Drosophila) | 0.546 | |
| Rb1 | retinoblastoma 1 | 0.490 | |
| Tbx1 | T-box 1 | 0.481 | |
| Jag1 | jagged 1 | 0.450 | |
| Hoxa1 | homeobox A1 | 0.439 | |
| Msx2 | homeobox, msh-like 2 | 0.430 | |
| Gata4 | GATA binding protein 4 | 0.427 | |
| Ror2 | receptor tyrosine kinase-like orphan receptor 2 | 0.424 | |
| Ptch1 | patched homolog 1 | 0.415 | |
| Hand2 | heart and neural crest derivatives expressed transcript 2 | 0.389 | |
| Fgf10 | fibroblast growth factor 10 | 0.369 | |
| Bmp7 | bone morphogenetic protein 7 | 0.362 | |
| Fgfr1 | fibroblast growth factor receptor 1 | 0.345 | |
| Gli2 | GLI-Kruppel family member GLI2 | 0.333 | |
| Erbb3 | v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) | 0.324 | |
| Pax6 | paired box gene 6 | 0.318 | |
| Twist2 | twist homolog 2 (Drosophila) | 0.311 | |
| Hand1 | heart and neural crest derivatives expressed transcript 1 | 0.300 | |
| Zeb1 | zinc finger E-box binding homeobox 1 | 0.282 | |
| Msx1 | homeobox, msh-like 1 | 0.257 | |
| Trp63 | transformation related protein 63 | 0.244 | |
| Tgfbr2 | transforming growth factor, beta receptor II | 0.242 | |
| Otx2 | orthodenticle homolog 2 (Drosophila) | 0.236 | |
| Chrd | chordin | 0.201 | |
| Lmna | lamin A | 0.188 | |
| Bmpr1a | bone morphogenetic protein receptor, type 1A | 0.187 | |
| Prrx1 | paired related homeobox 1 | 0.183 | |
| Gja1 | gap junction protein, alpha 1 | 0.172 | |
| Mmp14 | matrix metallopeptidase 14 (membrane-inserted) | 0.163 | |
| Pax2 | paired box gene 2 | 0.158 | |
| Efnb2 | ephrin B2 | 0.142 | |
| Nrg1 | neuregulin 1 | 0.141 | |
| Rarb | retinoic acid receptor, beta | 0.119 | |
| Phox2b | paired-like homeobox 2b | 0.116 | |
| Egfr | epidermal growth factor receptor | 0.107 | |
| Prrx2 | paired related homeobox 2 | 0.088 | |
| Chd7 | chromodomain helicase DNA binding protein 7 | 0.087 | |
| Cdkn1a | cyclin-dependent kinase inhibitor 1A (P21) | 0.068 | |
| Hspg2 | perlecan (heparan sulfate proteoglycan 2) | 0.061 | |
| Rara | retinoic acid receptor, alpha | 0.060 | |
| Foxg1 | forkhead box G1 | 0.058 | |
| Pthlh | parathyroid hormone-like peptide | 0.058 | |
| Vangl2 | vang-like 2 (van gogh, Drosophila) | 0.056 | |
| Rarg | retinoic acid receptor, gamma | 0.056 | |
| Dlx5 | distal-less homeobox 5 | 0.056 | |
| Nos3 | nitric oxide synthase 3, endothelial cell | 0.056 | |
| Alx4 | aristaless-like homeobox 4 | 0.055 | |
| Gfra1 | glial cell line derived neurotrophic factor family receptor alpha 1 | 0.055 | |
| Gata6 | GATA binding protein 6 | 0.054 | |
| Mdm2 | transformed mouse 3T3 cell double minute 2 | 0.053 | |
| Bmp2 | bone morphogenetic protein 2 | 0.051 | |
| Adam17 | a disintegrin and metallopeptidase domain 17 | 0.051 | |
| Gdnf | glial cell line derived neurotrophic factor | 0.050 | |
| Brca1 | breast cancer 1 | 0.050 | |
| Braf | Braf transforming gene | 0.049 | |
| Sox4 | SRY-box containing gene 4 | 0.048 | |
| Apoe | apolipoprotein E | 0.048 | |
| Col2a1 | collagen, type II, alpha 1 | 0.047 | |
| Pitx1 | paired-like homeodomain transcription factor 1 | 0.045 | |
| Mycn | v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian) | 0.045 | |
| Esr1 | estrogen receptor 1 (alpha) | 0.044 | |
| Foxa2 | forkhead box A2 | 0.044 | |
| Nr3c1 | nuclear receptor subfamily 3, group C, member 1 | 0.044 | |
| Smpd3 | sphingomyelin phosphodiesterase 3, neutral | 0.043 | |
| Tbx3 | T-box 3 | 0.042 | |
| Lepr | leptin receptor | 0.041 | |
| Lrp6 | low density lipoprotein receptor-related protein 6 | 0.041 |