IMP
Process View
The network for 'macromolecular complex remodeling' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.
Multiple Organisms
macromolecular complex remodeling
The acquisition, loss, or modification of macromolecules within a complex, resulting in the alteration of an existing complex.
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| APOA1 | apolipoprotein A-I | 1.000 | |
| ALB | albumin | 1.000 | |
| HP | haptoglobin | 0.998 | |
| APOC1 | apolipoprotein C-I | 0.989 | |
| APOE | apolipoprotein E | 0.987 | |
| APOA2 | apolipoprotein A-II | 0.968 | |
| A2M | alpha-2-macroglobulin | 0.963 | |
| APOC3 | apolipoprotein C-III | 0.913 | |
| LCAT | lecithin-cholesterol acyltransferase | 0.888 | |
| APOC2 | apolipoprotein C-II | 0.748 | |
| FGA | fibrinogen alpha chain | 0.590 | |
| TTR | transthyretin | 0.295 | |
| TNFRSF10C | tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain | 0.114 | |
| AHSG | alpha-2-HS-glycoprotein | 0.108 | |
| APOB | apolipoprotein B (including Ag(x) antigen) | 0.094 | |
| TXNDC2 | thioredoxin domain containing 2 (spermatozoa) | 0.084 | |
| CDK7 | cyclin-dependent kinase 7 | 0.076 | |
| RPL18A | ribosomal protein L18a | 0.072 | |
| PLTP | phospholipid transfer protein | 0.042 | |
| MAPT | microtubule-associated protein tau | 0.033 | |
| LDLR | low density lipoprotein receptor | 0.028 | |
| GPLD1 | glycosylphosphatidylinositol specific phospholipase D1 | 0.028 | |
| XPC | xeroderma pigmentosum, complementation group C | 0.028 | |
| MDK | midkine (neurite growth-promoting factor 2) | 0.027 | |
| FAM83C | family with sequence similarity 83, member C | 0.025 | |
| GTF2H1 | general transcription factor IIH, polypeptide 1, 62kDa | 0.022 | |
| PDCD4 | programmed cell death 4 (neoplastic transformation inhibitor) | 0.020 | |
| AKT2 | v-akt murine thymoma viral oncogene homolog 2 | 0.019 | |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.019 | |
| CLEC4G | C-type lectin domain family 4, member G | 0.019 | |
| TBP | TATA box binding protein | 0.018 | |
| F7 | coagulation factor VII (serum prothrombin conversion accelerator) | 0.017 | |
| CYP2C8 | cytochrome P450, family 2, subfamily C, polypeptide 8 | 0.017 | |
| HPX | hemopexin | 0.016 | |
| AMBP | alpha-1-microglobulin/bikunin precursor | 0.015 | |
| PTPN5 | protein tyrosine phosphatase, non-receptor type 5 (striatum-enriched) | 0.015 | |
| TF | transferrin | 0.015 | |
| F2 | coagulation factor II (thrombin) | 0.015 | |
| LIPC | lipase, hepatic | 0.014 | |
| ITIH1 | inter-alpha (globulin) inhibitor H1 | 0.014 | |
| ECSIT | ECSIT homolog (Drosophila) | 0.013 | |
| DNTT | deoxynucleotidyltransferase, terminal | 0.013 | |
| KRT16 | keratin 16 | 0.013 | |
| KRT1 | keratin 1 | 0.012 | |
| SCARB1 | scavenger receptor class B, member 1 | 0.012 | |
| SPEF2 | sperm flagellar 2 | 0.012 | |
| MSR1 | macrophage scavenger receptor 1 | 0.011 | |
| RAB9A | RAB9A, member RAS oncogene family | 0.011 | |
| H3F3B | H3 histone, family 3B (H3.3B) | 0.011 | |
| KIAA1377 | KIAA1377 | 0.010 | |
| RIBC2 | RIB43A domain with coiled-coils 2 | 0.010 | |
| CCL18 | chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated) | 0.010 |
Loading network...
Mus musculus
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| Apoe | apolipoprotein E | 0.996 | |
| Abca1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.690 | |
| Npc1 | Niemann Pick type C1 | 0.232 | |
| Apoa1 | apolipoprotein A-I | 0.206 | |
| Hnf4a | hepatic nuclear factor 4, alpha | 0.152 | |
| Lyz2 | lysozyme 2 | 0.064 | |
| Ldlr | low density lipoprotein receptor | 0.060 | |
| Plg | plasminogen | 0.057 | |
| Cebpa | CCAAT/enhancer binding protein (C/EBP), alpha | 0.051 | |
| Apoa2 | apolipoprotein A-II | 0.044 | |
| Aldob | aldolase B, fructose-bisphosphate | 0.034 | |
| Lpl | lipoprotein lipase | 0.028 | |
| F2 | coagulation factor II | 0.028 | |
| Prnp | prion protein | 0.027 | |
| Apoc3 | apolipoprotein C-III | 0.027 | |
| Gba | glucosidase, beta, acid | 0.025 | |
| Slc27a5 | solute carrier family 27 (fatty acid transporter), member 5 | 0.025 | |
| Gjb2 | gap junction protein, beta 2 | 0.024 | |
| Lrp1 | low density lipoprotein receptor-related protein 1 | 0.023 | |
| Gcgr | glucagon receptor | 0.023 | |
| Agt | angiotensinogen (serpin peptidase inhibitor, clade A, member 8) | 0.023 | |
| Lpin1 | lipin 1 | 0.020 | |
| Cfi | complement component factor i | 0.019 | |
| Apoa4 | apolipoprotein A-IV | 0.018 | |
| Ahsg | alpha-2-HS-glycoprotein | 0.018 | |
| Myo6 | myosin VI | 0.016 | |
| Lepr | leptin receptor | 0.015 | |
| Fgb | fibrinogen beta chain | 0.014 | |
| Cfh | complement component factor h | 0.014 | |
| Abhd5 | abhydrolase domain containing 5 | 0.014 | |
| Serpinf2 | serine (or cysteine) peptidase inhibitor, clade F, member 2 | 0.014 | |
| Pltp | phospholipid transfer protein | 0.014 | |
| C3 | complement component 3 | 0.014 | |
| Pdzk1 | PDZ domain containing 1 | 0.013 | |
| Slc2a4 | solute carrier family 2 (facilitated glucose transporter), member 4 | 0.013 | |
| Abcg1 | ATP-binding cassette, sub-family G (WHITE), member 1 | 0.013 | |
| Mertk | c-mer proto-oncogene tyrosine kinase | 0.012 | |
| Pnpla2 | patatin-like phospholipase domain containing 2 | 0.011 | |
| Cav1 | caveolin 1, caveolae protein | 0.011 | |
| Fgg | fibrinogen gamma chain | 0.011 | |
| Lat | linker for activation of T cells | 0.011 | |
| F12 | coagulation factor XII (Hageman factor) | 0.010 | |
| Ghr | growth hormone receptor | 0.010 |