The network for 'response to cell cycle checkpoint signaling' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

response to cell cycle checkpoint signaling

A cell cycle process, downstream of cell cycle checkpoint signaling, that delays or stops progression through the cell cycle and allows deficiencies and defects to be resolved.

Mus musculus
Name Description Probability Func Analog Organism
Ckap2 cytoskeleton associated protein 2 0.446
Gtse1 G two S phase expressed protein 1 0.441
Cdc20 cell division cycle 20 homolog (S. cerevisiae) 0.335
Plk1 polo-like kinase 1 (Drosophila) 0.310
Uhrf1 ubiquitin-like, containing PHD and RING finger domains, 1 0.289
Kif2c kinesin family member 2C 0.137
Cenpm centromere protein M 0.131
4930427A07Rik RIKEN cDNA 4930427A07 gene 0.103
Mybl2 myeloblastosis oncogene-like 2 0.102
Ncaph non-SMC condensin I complex, subunit H 0.090
Foxm1 forkhead box M1 0.089
Ccdc99 coiled-coil domain containing 99 0.089
Fam64a family with sequence similarity 64, member A 0.087
Dlgap5 discs, large (Drosophila) homolog-associated protein 5 0.073
Fam54a family with sequence similarity 54, member A 0.070
Efemp2 epidermal growth factor-containing fibulin-like extracellular matrix protein 2 0.069
Exo1 exonuclease 1 0.069
Kif4 kinesin family member 4 0.064
Hmmr hyaluronan mediated motility receptor (RHAMM) 0.061
Aurkb aurora kinase B 0.056
Cdca5 cell division cycle associated 5 0.056
Ccnf cyclin F 0.056
Cdc25c cell division cycle 25 homolog C (S. pombe) 0.055
Idua iduronidase, alpha-L- 0.053
Cdc45 cell division cycle 45 homolog (S. cerevisiae) 0.052
Kif20a kinesin family member 20A 0.048
Bub1b budding uninhibited by benzimidazoles 1 homolog, beta (S. cerevisiae) 0.044
Mcm10 minichromosome maintenance deficient 10 (S. cerevisiae) 0.044
Ccnb2 cyclin B2 0.043
Cdk1 cyclin-dependent kinase 1 0.040
Pask PAS domain containing serine/threonine kinase 0.035
Mxd3 Max dimerization protein 3 0.033
Eme1 essential meiotic endonuclease 1 homolog 1 (S. pombe) 0.033
Kif22 kinesin family member 22 0.032
Gsg2 germ cell-specific gene 2 0.032
Cep55 centrosomal protein 55 0.031
BC030867 cDNA sequence BC030867 0.030
Nprl2 nitrogen permease regulator-like 2 (S. cerevisiae) 0.029
Ndc80 NDC80 homolog, kinetochore complex component (S. cerevisiae) 0.029
Lrdd leucine-rich and death domain containing 0.028
Chtf18 CTF18, chromosome transmission fidelity factor 18 homolog (S. cerevisiae) 0.024
Aspm asp (abnormal spindle)-like, microcephaly associated (Drosophila) 0.023
Chaf1b chromatin assembly factor 1, subunit B (p60) 0.021
Fanca Fanconi anemia, complementation group A 0.020
Iqgap3 IQ motif containing GTPase activating protein 3 0.020
E130303B06Rik RIKEN cDNA E130303B06 gene 0.020
Ska1 spindle and kinetochore associated complex subunit 1 0.019
Mis18bp1 MIS18 binding protein 1 0.016
Fanci Fanconi anemia, complementation group I 0.016
Ccne1 cyclin E1 0.016
D2Ertd750e DNA segment, Chr 2, ERATO Doi 750, expressed 0.016
Ube2c ubiquitin-conjugating enzyme E2C 0.015
Birc5 baculoviral IAP repeat-containing 5 0.015
Cenpf centromere protein F 0.014
Ropn1 ropporin, rhophilin associated protein 1 0.013
Cenpn centromere protein N 0.012
Asf1b ASF1 anti-silencing function 1 homolog B (S. cerevisiae) 0.012
Cryzl1 crystallin, zeta (quinone reductase)-like 1 0.011
Prc1 protein regulator of cytokinesis 1 0.011
Ccnb1 cyclin B1 0.011
Fbxo25 F-box protein 25 0.011
Cdca2 cell division cycle associated 2 0.011
Ribc1 RIB43A domain with coiled-coils 1 0.010
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Danio rerio
Name Description Probability Func Analog Organism
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Drosophila melanogaster
Name Description Probability Func Analog Organism
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Homo sapiens
Name Description Probability Func Analog Organism
SLX4 SLX4 structure-specific endonuclease subunit homolog (S. cerevisiae) 0.985
SLX1B SLX1 structure-specific endonuclease subunit homolog B (S. cerevisiae) 0.800
MUS81 MUS81 endonuclease homolog (S. cerevisiae) 0.575
EME1 essential meiotic endonuclease 1 homolog 1 (S. pombe) 0.160
ERCC4 excision repair cross-complementing rodent repair deficiency, complementation group 4 0.133
ERCC1 excision repair cross-complementing rodent repair deficiency, complementation group 1 (includes overlapping antisense sequence) 0.093
C20orf94 chromosome 20 open reading frame 94 0.028
TERF2 telomeric repeat binding factor 2 0.024
TERF2IP telomeric repeat binding factor 2, interacting protein 0.011
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Rattus norvegicus
Name Description Probability Func Analog Organism
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism
MEX67 Mex67p 0.220
CLP1 Clp1p 0.137
MLP2 Mlp2p 0.117
NUP157 Nup157p 0.053
NSP1 Nsp1p 0.043
MLP1 Mlp1p 0.042
HRP1 Hrp1p 0.041
NBL1 Nbl1p 0.037
RNA14 Rna14p 0.031
MAK21 Mak21p 0.028
NUP49 Nup49p 0.028
SRD1 Srd1p 0.025
YLR264C-A hypothetical protein 0.024
SGN1 Sgn1p 0.024
PBP2 Pbp2p 0.024
SPT5 Spt5p 0.024
CUP1-1 Cup1-1p 0.023
YLR162W hypothetical protein 0.023
POM34 Pom34p 0.021
YGR017W hypothetical protein 0.021
ARP10 Arp10p 0.021
ARG8 Arg8p 0.020
LEU2 Leu2p 0.020
YOL038C-A hypothetical protein 0.020
MER1 Mer1p 0.019
CRP1 Crp1p 0.018
SLK19 Slk19p 0.017
PRS2 Prs2p 0.017
YAR068W hypothetical protein 0.017
URA3 Ura3p 0.016
YPR157W hypothetical protein 0.016
RNA15 Rna15p 0.016
GRE2 Gre2p 0.016
TAE2 Tae2p 0.016
YLR042C hypothetical protein 0.015
ICS2 Ics2p 0.015
SPC110 Spc110p 0.015
ATP6 Atp6p 0.015
GYL1 Gyl1p 0.015
TYE7 Tye7p 0.015
ZPS1 Zps1p 0.014
SPT6 Spt6p 0.014
HO Hop 0.014
YBR013C hypothetical protein 0.014
AUA1 Aua1p 0.014
ASM4 Asm4p 0.014
SWC7 Swc7p 0.014
FMT1 Fmt1p 0.014
UBA2 Uba2p 0.014
YPL014W hypothetical protein 0.014
RRP17 Rrp17p 0.014
ADH2 Adh2p 0.013
MFT1 Mft1p 0.013
SPL2 Spl2p 0.013
ARO10 Aro10p 0.013
YIL151C hypothetical protein 0.013
MTW1 Mtw1p 0.013
HPF1 Hpf1p 0.013
BSC1 Bsc1p 0.013
SMC4 Smc4p 0.013
YLR419W hypothetical protein 0.012
CPD1 Cpd1p 0.012
RPF1 Rpf1p 0.012
TAD2 Tad2p 0.012
HXT3 Hxt3p 0.012
RTT105 Rtt105p 0.012
ARO9 Aro9p 0.012
SRP68 Srp68p 0.012
CET1 Cet1p 0.012
YOL013W-A hypothetical protein 0.012
PNS1 Pns1p 0.011
IZH4 Izh4p 0.011
DML1 Dml1p 0.011
SCM4 Scm4p 0.011
CBF2 Cbf2p 0.011
YPR096C hypothetical protein 0.011
YIR035C hypothetical protein 0.011
HOR2 Hor2p 0.011
DIC1 Dic1p 0.011
YLR040C hypothetical protein 0.011
RNP1 Rnp1p 0.011
CUP1-2 Cup1-2p 0.011
UPS3 Ups3p 0.011
MFA2 Mfa2p 0.011
ORC6 Orc6p 0.010
SRX1 Srx1p 0.010
YPL067C hypothetical protein 0.010
YJL181W hypothetical protein 0.010
YML003W hypothetical protein 0.010
SUB1 Sub1p 0.010
YKR075C hypothetical protein 0.010
YJL218W hypothetical protein 0.010
LCL1 Lcl1p 0.010