The network for 'positive regulation of cell proliferation' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

positive regulation of cell proliferation

Any process that activates or increases the rate or extent of cell proliferation.

Rattus norvegicus
Name Description Probability Func Analog Organism
Gjb3 gap junction protein, beta 3 0.642
Cga glycoprotein hormones, alpha polypeptide 0.587
Ptpn7 protein tyrosine phosphatase, non-receptor type 7 0.569
Fgfr2 fibroblast growth factor receptor 2 0.567
Zp1 zona pellucida glycoprotein 1 (sperm receptor) 0.535
Pgc progastricsin (pepsinogen C) 0.520
Cd4 Cd4 molecule 0.513
Cd40lg CD40 ligand 0.500
Ddr1 discoidin domain receptor tyrosine kinase 1 0.500
Cxcl6 chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2) 0.485
Foxd1 forkhead box D1 0.480
Chat choline acetyltransferase 0.460
Fgf7 fibroblast growth factor 7 0.453
Itgam integrin, alpha M 0.452
Ascl1 achaete-scute complex homolog 1 (Drosophila) 0.426
Sirpa signal-regulatory protein alpha 0.410
Prrx1 paired related homeobox 1 0.405
Prl6a1 prolactin family 6, subfamily a, member 1 0.403
Adrb1 adrenergic, beta-1-, receptor 0.403
Nefm neurofilament, medium polypeptide 0.396
Adora2a adenosine A2a receptor 0.390
Anxa5 annexin A5 0.388
Cd151 CD151 molecule (Raph blood group) 0.385
Egr2 early growth response 2 0.384
Gja1 gap junction protein, alpha 1 0.382
Nptxr neuronal pentraxin receptor 0.380
Cacng7 calcium channel, voltage-dependent, gamma subunit 7 0.378
Slc18a2 solute carrier family 18 (vesicular monoamine), member 2 0.372
Cdh6 cadherin 6 0.365
Klf6 Kruppel-like factor 6 0.363
Npffr2 neuropeptide FF receptor 2 0.362
Htr5b 5-hydroxytryptamine (serotonin) receptor 5B 0.358
Vom2r27 vomeronasal 2 receptor, 27 0.358
Anxa1 annexin A1 0.358
Il9r interleukin 9 receptor 0.356
Grk1 G protein-coupled receptor kinase 1 0.353
Slco2b1 solute carrier organic anion transporter family, member 2b1 0.351
Ms4a2 membrane-spanning 4-domains, subfamily A, member 2 (Fc fragment of IgE, high affinity I, receptor for; beta polypeptide) 0.345
Utrn utrophin 0.344
Trim66 tripartite motif-containing 66 0.343
Casp2 caspase 2 0.342
Fgr Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog 0.339
Oprm1 opioid receptor, mu 1 0.332
Bcl2 B-cell CLL/lymphoma 2 0.328
Dchs1 dachsous 1 (Drosophila) 0.327
Grpr gastrin releasing peptide receptor 0.324
Mamdc4 MAM domain containing 4 0.323
Gnrhr gonadotropin releasing hormone receptor 0.320
Areg amphiregulin 0.318
Ptafr platelet-activating factor receptor 0.317
Ccnd1 cyclin D1 0.316
Cd5 Cd5 molecule 0.314
Olfml2b olfactomedin-like 2B 0.314
Hbe2 hemoglobin, epsilon 2 0.313
Sstr5 somatostatin receptor 5 0.312
Fos FBJ osteosarcoma oncogene 0.309
Fgf16 fibroblast growth factor 16 0.303
S100a10 S100 calcium binding protein A10 0.298
Aqp5 aquaporin 5 0.298
Tas2r107 taste receptor, type 2, member 107 0.297
Cmtm2a CKLF-like MARVEL transmembrane domain containing 2A 0.295
Akr1c18 aldo-keto reductase family 1, member C18 0.294
Col10a1 collagen, type X, alpha 1 0.293
Foxs1 forkhead box S1 0.292
Egr1 early growth response 1 0.292
Shox2 short stature homeobox 2 0.289
Ednra endothelin receptor type A 0.289
Gdf10 growth differentiation factor 10 0.287
Dnase1l3 deoxyribonuclease 1-like 3 0.285
Agtr1a angiotensin II receptor, type 1a 0.285
Anxa2 annexin A2 0.285
Prss22 protease, serine, 22 0.280
Fosl1 fos-like antigen 1 0.279
Runx1 runt-related transcription factor 1 0.274
Bcan brevican 0.273
Il10ra interleukin 10 receptor, alpha 0.271
Gpr20 G protein-coupled receptor 20 0.267
Sfrp4 secreted frizzled-related protein 4 0.265
St8sia4 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4 0.264
Pip prolactin induced protein 0.262
Trim47 tripartite motif-containing 47 0.262
Purb purine rich element binding protein B 0.262
Kcnj4 potassium inwardly-rectifying channel, subfamily J, member 4 0.259
Phox2a paired-like homeobox 2a 0.259
Plau plasminogen activator, urokinase 0.258
Serpini2 serine (or cysteine) peptidase inhibitor, clade I, member 2 0.258
Ccl4 chemokine (C-C motif) ligand 4 0.256
Pcdhb12 protocadherin beta 12 0.255
Cyp11b3 cytochrome P450, family 11, subfamily b, polypeptide 3 0.255
Cx3cr1 chemokine (C-X3-C motif) receptor 1 0.252
Vcan versican 0.252
Tbx2 T-box 2 0.250
Twist2 twist homolog 2 (Drosophila) 0.249
Olr1361 olfactory receptor 1361 0.249
Hcn4 hyperpolarization activated cyclic nucleotide-gated potassium channel 4 0.247
Nos1 nitric oxide synthase 1, neuronal 0.246
Ptk2b PTK2B protein tyrosine kinase 2 beta 0.245
Drd3 dopamine receptor D3 0.241
Hnrnpf heterogeneous nuclear ribonucleoprotein F 0.239
Reg3a regenerating islet-derived 3 alpha 0.237
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
nhr-67 Protein NHR-67 0.013
egl-18 Protein EGL-18 0.011
unc-73 Protein UNC-73 0.010
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Danio rerio
Name Description Probability Func Analog Organism
notch1a notch homolog 1a 0.983
aldh1a2 aldehyde dehydrogenase 1 family, member A2 0.867
shha sonic hedgehog a 0.841
fgf17 fibroblast growth factor 17 0.778
tal1 T-cell acute lymphocytic leukemia 1 0.728
tcf7l2 transcription factor 7-like 2 (T-cell specific, HMG-box) 0.662
sulf1 sulfatase 1 0.658
kdrl kinase insert domain receptor like 0.616
kita kit receptor a 0.601
gli1 GLI-Kruppel family member 1 0.541
ndr2 nodal-related 2 0.522
dld deltaD 0.507
snai1a snail homolog 1a (Drosophila) 0.474
mitfa microphthalmia-associated transcription factor a 0.459
tbx2b T-box 2b 0.456
myca myelocytomatosis oncogene a 0.412
boc brother of CDO 0.403
eya1 eyes absent homolog 1 0.365
dlx5a distal-less homeobox gene 5a 0.357
chd chordin 0.344
bmp4 bone morphogenetic protein 4 0.328
jag2 jagged 2 0.309
lratb lecithin retinol acyltransferase b (phosphatidylcholine--retinol O-acyltransferase b) 0.280
her6 hairy-related 6 0.279
fgfr1a fibroblast growth factor receptor 1a 0.270
hoxd4a homeo box D4a 0.254
hoxb1b homeo box B1b 0.248
wnt5b wingless-type MMTV integration site family, member 5b 0.248
tbx16 T-box gene 16 0.229
bmp2b bone morphogenetic protein 2b 0.219
dusp6 dual specificity phosphatase 6 0.219
lhx1a LIM homeobox 1a 0.206
alcama activated leukocyte cell adhesion molecule a 0.205
ptch1 patched 1 0.198
mib mind bomb 0.190
notch2 notch homolog 2 0.189
neo1 neogenin 1 0.186
itgb1b integrin, beta 1b 0.182
pax6a paired box gene 6a 0.177
ets1a v-ets erythroblastosis virus E26 oncogene homolog 1a 0.176
nod1 nucleotide-binding oligomerization domain containing 1 0.172
dnmt4 DNA (cytosine-5-)-methyltransferase 4 0.169
gna12 guanine nucleotide binding protein (G protein) alpha 12 0.162
wnt2 wingless-type MMTV integration site family member 2 0.156
etv2 ets variant gene 2 0.149
tshb thyroid stimulating hormone, beta subunit 0.148
ascl1a achaete-scute complex-like 1a (Drosophila) 0.140
notch3 notch homolog 3 0.136
hoxa2b homeo box A2b 0.136
six1b sine oculis homeobox homolog 1b 0.132
otpb orthopedia homolog b 0.130
tbx1 T-box 1 0.127
gsc goosecoid 0.125
tp53 tumor protein p53 0.124
fgf3 fibroblast growth factor 3 0.123
foxi1 forkhead box I1 0.119
flh floating head 0.119
otpa orthopedia homolog a 0.118
flt4 fms-related tyrosine kinase 4 0.115
vsx2 visual system homeobox 2 0.113
fgf8a fibroblast growth factor 8 a 0.113
nkx2.5 NK2 transcription factor related 5 0.108
igf1 insulin-like growth factor 1 0.107
mmp9 matrix metalloproteinase 9 0.106
evx1 even-skipped homeobox 1 0.104
wnt11r wingless-type MMTV integration site family, member 11, related 0.101
irx3a iroquois homeobox protein 3a 0.100
bmp7b bone morphogenetic protein 7b 0.099
tie1 endothelium-specific receptor tyrosine kinase 1 0.099
acvr1l activin A receptor, type I like 0.096
eomesa eomesodermin homolog a 0.095
fli1a friend leukemia integration 1a 0.089
il6st interleukin 6 signal transducer 0.088
wls wntless homolog (Drosophila) 0.087
erbb2 v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog 0.086
hoxc8a homeo box C8a 0.085
sox9b SRY-box containing gene 9b 0.083
tnfa tumor necrosis factor a (TNF superfamily, member 2) 0.082
rerea arginine-glutamic acid dipeptide (RE) repeats a 0.082
runx2a runt-related transcription factor 2a 0.081
smad9 MAD homolog 9 (Drosophila) 0.080
epha4b eph receptor A4b 0.080
fras1 Fraser syndrome 1 0.079
nrg1 neuregulin 1 0.078
her7 hairy and enhancer of split related-7 0.076
dzip1 DAZ interacting protein 1 0.075
arhgef7b Rho guanine nucleotide exchange factor (GEF) 7b 0.074
dlb deltaB 0.073
loxl3b lysyl oxidase-like 3b 0.073
gdnf glial cell derived neurotrophic factor 0.072
barx1 BarH-like homeobox 1 0.071
mab21l2 mab-21-like 2 0.070
axin2 axin 2 (conductin, axil) 0.070
jag1b jagged 1b 0.070
si:dkey-8l13.4 si:dkey-8l13.4 0.069
msxc muscle segment homeobox C 0.069
tcf7l1a transcription factor 7-like 1a (T-cell specific, HMG-box) 0.068
igf1rb insulin-like growth factor 1b receptor 0.067
dkk1b dickkopf 1b 0.066
irx4a iroquois homeobox protein 4a 0.066
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Drosophila melanogaster
Name Description Probability Func Analog Organism
ci cubitus interruptus 0.992
brm brahma 0.928
E(spl) Enhancer of split 0.885
nej nejire 0.874
stck steamer duck 0.743
N Notch 0.721
Akt1 CG4006 gene product from transcript CG4006-RA 0.712
shn schnurri 0.711
Mad Mothers against dpp 0.708
arm armadillo 0.684
gro groucho 0.668
so sine oculis 0.652
stg string 0.561
mnb minibrain 0.559
dac dachshund 0.517
dsh dishevelled 0.487
dm diminutive 0.486
InR Insulin-like receptor 0.486
Rac2 CG8556 gene product from transcript CG8556-RA 0.486
Dad Daughters against dpp 0.478
S6k RPS6-p70-protein kinase 0.477
Rac1 CG2248 gene product from transcript CG2248-RA 0.426
bab2 CG9102 gene product from transcript CG9102-RA 0.396
Pi3K92E CG4141 gene product from transcript CG4141-RB 0.392
stumps CG31317 gene product from transcript CG31317-RC 0.390
drk downstream of receptor kinase 0.389
spi spitz 0.387
slp1 sloppy paired 1 0.385
HLHmdelta E(spl) region transcript mdelta 0.379
nkd naked cuticle 0.371
rl rolled 0.345
norpA no receptor potential A 0.340
Ras85D Ras oncogene at 85D 0.337
Atpalpha Na pump alpha subunit 0.334
elav embryonic lethal abnormal vision 0.325
shi shibire 0.324
par-1 CG8201 gene product from transcript CG8201-RA 0.320
aop anterior open 0.317
Snr1 Snf5-related 1 0.316
ush u-shaped 0.314
Pk61C Protein kinase 61C 0.308
fz frizzled 0.307
dome domeless 0.299
eve even skipped 0.296
babo baboon 0.292
hh hedgehog 0.276
fng fringe 0.265
wg wingless 0.251
SoxN SoxNeuro 0.244
Rab5 Rab-protein 5 0.238
htl heartless 0.236
dpp decapentaplegic 0.234
tin tinman 0.221
ey eyeless 0.217
HLHmgamma E(spl) region transcript mgamma 0.214
Egfr Epidermal growth factor receptor 0.206
crb crumbs 0.204
Moe Moesin 0.203
Fmr1 CG6203 gene product from transcript CG6203-RC 0.201
en engrailed 0.201
put punt 0.195
exba extra bases 0.193
kni knirps 0.191
jub Ajuba LIM protein 0.187
os outstretched 0.185
sev sevenless 0.184
dpn deadpan 0.181
Iswi Imitation SWI 0.177
ago archipelago 0.175
ttk tramtrack 0.174
Ubx Ultrabithorax 0.173
brk brinker 0.166
NetB Netrin-B 0.165
dap dacapo 0.161
da daughterless 0.159
kibra kibra ortholog 0.157
CycB Cyclin B 0.150
pnt pointed 0.149
Rbf Retinoblastoma-family protein 0.147
beta-Spec beta Spectrin 0.146
pic piccolo 0.144
al aristaless 0.141
HLHm5 E(spl) region transcript m5 0.137
Spn27A Serpin 27A 0.137
Jra Jun-related antigen 0.137
14-3-3epsilon CG31196 gene product from transcript CG31196-RA 0.136
hipk homeodomain interacting protein kinase 0.134
Mhc Myosin heavy chain 0.133
disco disconnected 0.133
HLHm7 E(spl) region transcript m7 0.131
csw corkscrew 0.131
grn grain 0.130
bel belle 0.130
Nrt Neurotactin 0.128
Su(H) Suppressor of Hairless 0.127
Tom Twin of m4 0.126
polo CG12306 gene product from transcript CG12306-RA 0.124
ths thisbe 0.123
kay kayak 0.122
myoglianin CG1838 gene product from transcript CG1838-RD 0.122
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Homo sapiens
Name Description Probability Func Analog Organism
EGFR epidermal growth factor receptor 1.000
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) 1.000
ERBB3 v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) 1.000
ESR1 estrogen receptor 1 1.000
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) 1.000
SRC v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) 1.000
ERBB2 v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) 1.000
PTPN1 protein tyrosine phosphatase, non-receptor type 1 0.999
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide 0.999
SHC1 SHC (Src homology 2 domain containing) transforming protein 1 0.999
CDK2 cyclin-dependent kinase 2 0.999
SYK spleen tyrosine kinase 0.999
RB1 retinoblastoma 1 0.998
TP53 tumor protein p53 0.998
CBL Cas-Br-M (murine) ecotropic retroviral transforming sequence 0.995
GRB2 growth factor receptor-bound protein 2 0.995
CAV1 caveolin 1, caveolae protein, 22kDa 0.993
MDM2 Mdm2 p53 binding protein homolog (mouse) 0.992
HDAC1 histone deacetylase 1 0.990
JAG1 jagged 1 0.987
FGFR2 fibroblast growth factor receptor 2 0.986
SMAD2 SMAD family member 2 0.983
NME2 non-metastatic cells 2, protein (NM23B) expressed in 0.983
ABL1 c-abl oncogene 1, non-receptor tyrosine kinase 0.979
PDGFRB platelet-derived growth factor receptor, beta polypeptide 0.978
RAF1 v-raf-1 murine leukemia viral oncogene homolog 1 0.976
CD80 CD80 molecule 0.976
EP300 E1A binding protein p300 0.974
E2F1 E2F transcription factor 1 0.971
FN1 fibronectin 1 0.970
BCL2 B-cell CLL/lymphoma 2 0.969
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 0.968
MMP2 matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase) 0.965
NOTCH1 notch 1 0.960
CRKL v-crk sarcoma virus CT10 oncogene homolog (avian)-like 0.960
VIM vimentin 0.960
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide 0.956
PDGFRA platelet-derived growth factor receptor, alpha polypeptide 0.955
ICAM1 intercellular adhesion molecule 1 0.951
PTPN6 protein tyrosine phosphatase, non-receptor type 6 0.948
FBLN1 fibulin 1 0.947
FYN FYN oncogene related to SRC, FGR, YES 0.945
RUNX1 runt-related transcription factor 1 0.939
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) 0.927
IL6 interleukin 6 (interferon, beta 2) 0.926
NOTCH3 notch 3 0.918
SOCS3 suppressor of cytokine signaling 3 0.918
TAL1 T-cell acute lymphocytic leukemia 1 0.914
BRCA1 breast cancer 1, early onset 0.913
PTEN phosphatase and tensin homolog 0.913
NR4A3 nuclear receptor subfamily 4, group A, member 3 0.910
HDAC2 histone deacetylase 2 0.907
TCF3 transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47) 0.904
LYN v-yes-1 Yamaguchi sarcoma viral related oncogene homolog 0.904
RING1 ring finger protein 1 0.904
IL8 interleukin 8 0.902
FGF1 fibroblast growth factor 1 (acidic) 0.901
SMAD4 SMAD family member 4 0.900
TFDP1 transcription factor Dp-1 0.900
MMP14 matrix metallopeptidase 14 (membrane-inserted) 0.897
CCR5 chemokine (C-C motif) receptor 5 0.888
PLAUR plasminogen activator, urokinase receptor 0.885
TIRAP toll-interleukin 1 receptor (TIR) domain containing adaptor protein 0.880
POU3F2 POU class 3 homeobox 2 0.877
CD3E CD3e molecule, epsilon (CD3-TCR complex) 0.876
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta) 0.874
ENG endoglin 0.874
IL6ST interleukin 6 signal transducer (gp130, oncostatin M receptor) 0.873
IGF1R insulin-like growth factor 1 receptor 0.863
PDGFB platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog) 0.853
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 0.851
CCL5 chemokine (C-C motif) ligand 5 0.848
TNFAIP3 tumor necrosis factor, alpha-induced protein 3 0.847
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide) 0.846
MET met proto-oncogene (hepatocyte growth factor receptor) 0.845
CALM1 calmodulin 1 (phosphorylase kinase, delta) 0.841
AXL AXL receptor tyrosine kinase 0.835
GRB7 growth factor receptor-bound protein 7 0.833
CCNE1 cyclin E1 0.833
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 0.831
FLT1 fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) 0.826
AR androgen receptor 0.825
CCL22 chemokine (C-C motif) ligand 22 0.823
IRS1 insulin receptor substrate 1 0.822
NR4A1 nuclear receptor subfamily 4, group A, member 1 0.809
RBBP4 retinoblastoma binding protein 4 0.800
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 0.800
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma 0.799
NCOA6 nuclear receptor coactivator 6 0.797
PLAU plasminogen activator, urokinase 0.793
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) 0.792
MAPT microtubule-associated protein tau 0.790
IL12B interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40) 0.787
CDK1 cyclin-dependent kinase 1 0.782
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain 0.782
TNF tumor necrosis factor 0.776
CXCL9 chemokine (C-X-C motif) ligand 9 0.774
YWHAQ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide 0.764
SKP2 S-phase kinase-associated protein 2 (p45) 0.757
PLCG1 phospholipase C, gamma 1 0.756
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Mus musculus
Name Description Probability Func Analog Organism
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism