The network for 'response to camp' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

response to camp

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cAMP (cyclic AMP, adenosine 3',5'-cyclophosphate) stimulus.

Rattus norvegicus
Name Description Probability Func Analog Organism
Fos FBJ osteosarcoma oncogene 0.985
Egr1 early growth response 1 0.977
Col1a1 collagen, type I, alpha 1 0.943
Btg2 BTG family, member 2 0.923
Junb jun B proto-oncogene 0.883
Col3a1 collagen, type III, alpha 1 0.813
Ppp1r15a protein phosphatase 1, regulatory (inhibitor) subunit 15A 0.775
Nr4a1 nuclear receptor subfamily 4, group A, member 1 0.748
C3 complement component 3 0.666
Ahsg alpha-2-HS-glycoprotein 0.607
Nr4a3 nuclear receptor subfamily 4, group A, member 3 0.583
Aldoa aldolase A, fructose-bisphosphate 0.556
Ppard peroxisome proliferator-activated receptor delta 0.542
Gapdh glyceraldehyde-3-phosphate dehydrogenase 0.484
Col1a2 collagen, type I, alpha 2 0.481
Errfi1 ERBB receptor feedback inhibitor 1 0.475
Tpi1 triosephosphate isomerase 1 0.462
Arc activity-regulated cytoskeleton-associated protein 0.456
Apoh apolipoprotein H (beta-2-glycoprotein I) 0.454
Serpina3k serine (or cysteine) peptidase inhibitor, clade A, member 3K 0.430
Lepr leptin receptor 0.417
Serpina3m serine (or cysteine) proteinase inhibitor, clade A, member 3M 0.413
Rxra retinoid X receptor alpha 0.413
Nr5a2 nuclear receptor subfamily 5, group A, member 2 0.399
Pkm2 pyruvate kinase, muscle 0.375
Rgs1 regulator of G-protein signaling 1 0.364
Egr2 early growth response 2 0.362
Eno1 enolase 1, (alpha) 0.357
Serpind1 serpin peptidase inhibitor, clade D (heparin cofactor), member 1 0.348
Hrg histidine-rich glycoprotein 0.346
Ptgs2 prostaglandin-endoperoxide synthase 2 0.344
Aldob aldolase B, fructose-bisphosphate 0.338
Ier2 immediate early response 2 0.330
Fn1 fibronectin 1 0.327
Col5a2 collagen, type V, alpha 2 0.326
Ttr transthyretin 0.325
Cryaa crystallin, alpha A 0.323
Bgn biglycan 0.322
Clec4f C-type lectin domain family 4, member f 0.314
Cxcl2 chemokine (C-X-C motif) ligand 2 0.310
Zfp36 zinc finger protein 36 0.300
Igfals insulin-like growth factor binding protein, acid labile subunit 0.293
Lum lumican 0.289
Aqp8 aquaporin 8 0.289
Atf3 activating transcription factor 3 0.284
Slc2a3 solute carrier family 2 (facilitated glucose transporter), member 3 0.277
Apcs amyloid P component, serum 0.275
Pla2g1b phospholipase A2, group IB, pancreas 0.273
Gabrr3 gamma-aminobutyric acid (GABA) receptor, rho 3 0.270
Apoa1 apolipoprotein A-I 0.268
Klf4 Kruppel-like factor 4 (gut) 0.267
Pgk1 phosphoglycerate kinase 1 0.266
Vip vasoactive intestinal peptide 0.258
Mmp3 matrix metallopeptidase 3 0.256
Rgs9 regulator of G-protein signaling 9 0.256
Dcn decorin 0.252
Chrna2 cholinergic receptor, nicotinic, alpha 2 (neuronal) 0.249
Cpb2 carboxypeptidase B2 (plasma) 0.244
Cbs cystathionine beta synthase 0.241
Nr4a2 nuclear receptor subfamily 4, group A, member 2 0.234
Unc5b unc-5 homolog B (C. elegans) 0.229
Synpo synaptopodin 0.228
Gabra1 gamma-aminobutyric acid (GABA) A receptor, alpha 1 0.226
Apoa5 apolipoprotein A-V 0.224
Spp2 secreted phosphoprotein 2 0.220
Fosl2 fos-like antigen 2 0.216
Mmp9 matrix metallopeptidase 9 0.216
Anxa1 annexin A1 0.215
Dusp1 dual specificity phosphatase 1 0.214
Chrm1 cholinergic receptor, muscarinic 1 0.213
Ngf nerve growth factor (beta polypeptide) 0.211
Foxa3 forkhead box A3 0.210
Eln elastin 0.206
Dhdpsl dihydrodipicolinate synthase-like, mitochondrial 0.204
Hpx hemopexin 0.203
Sult1a1 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 0.203
Aqp9 aquaporin 9 0.200
Insr insulin receptor 0.198
Rdh7 retinol dehydrogenase 7 0.195
Serpina1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 0.194
Cyp4a10 cytochrome P450, family 4, subfamily a, polypeptide 10 0.192
Slc22a13 solute carrier family 22 (organic anion transporter), member 13 0.191
Gata6 GATA binding protein 6 0.186
Afp alpha-fetoprotein 0.185
A1i3 alpha-1-inhibitor III 0.184
Slc5a3 solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 0.183
Notch1 Notch homolog 1, translocation-associated (Drosophila) 0.183
Jun Jun oncogene 0.183
Tbxa2r thromboxane A2 receptor 0.180
Mif macrophage migration inhibitory factor 0.179
Reg3g regenerating islet-derived 3 gamma 0.179
Rorb RAR-related orphan receptor B 0.178
Fev FEV (ETS oncogene family) 0.178
Gc group specific component 0.176
Gjb3 gap junction protein, beta 3 0.173
Dab2 disabled homolog 2 (Drosophila) 0.172
Hpn hepsin 0.170
Cyp7a1 cytochrome P450, family 7, subfamily a, polypeptide 1 0.170
RT1-M4 RT1 class Ib, locus M4 0.167
Serpina3n serine (or cysteine) peptidase inhibitor, clade A, member 3N 0.165
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Danio rerio
Name Description Probability Func Analog Organism
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Drosophila melanogaster
Name Description Probability Func Analog Organism
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Homo sapiens
Name Description Probability Func Analog Organism
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 0.992
EGR1 early growth response 1 0.981
JUNB jun B proto-oncogene 0.974
KCNQ1 potassium voltage-gated channel, KQT-like subfamily, member 1 0.941
ATF3 activating transcription factor 3 0.879
CCNE1 cyclin E1 0.870
NR4A2 nuclear receptor subfamily 4, group A, member 2 0.830
NR4A3 nuclear receptor subfamily 4, group A, member 3 0.809
KCNE1 potassium voltage-gated channel, Isk-related family, member 1 0.804
JUN jun proto-oncogene 0.732
FOSB FBJ murine osteosarcoma viral oncogene homolog B 0.638
FOS FBJ murine osteosarcoma viral oncogene homolog 0.605
PTPN13 protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) 0.603
C1R complement component 1, r subcomponent 0.581
ANGPT2 angiopoietin 2 0.572
ZFP36 zinc finger protein 36, C3H type, homolog (mouse) 0.562
EGR3 early growth response 3 0.467
NOSTRIN nitric oxide synthase trafficker 0.409
CCND1 cyclin D1 0.404
MAPK8 mitogen-activated protein kinase 8 0.400
IER2 immediate early response 2 0.361
NR4A1 nuclear receptor subfamily 4, group A, member 1 0.337
PLAT plasminogen activator, tissue 0.335
RAF1 v-raf-1 murine leukemia viral oncogene homolog 1 0.325
EGR2 early growth response 2 0.312
AXL AXL receptor tyrosine kinase 0.220
DRD2 dopamine receptor D2 0.220
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 0.215
PDLIM7 PDZ and LIM domain 7 (enigma) 0.212
RAP1A RAP1A, member of RAS oncogene family 0.205
IL6 interleukin 6 (interferon, beta 2) 0.194
PRKAR2A protein kinase, cAMP-dependent, regulatory, type II, alpha 0.178
UHRF2 ubiquitin-like with PHD and ring finger domains 2 0.175
PLAU plasminogen activator, urokinase 0.165
ANGPT1 angiopoietin 1 0.160
FGFR1 fibroblast growth factor receptor 1 0.154
PHYHIPL phytanoyl-CoA 2-hydroxylase interacting protein-like 0.137
MDM2 Mdm2 p53 binding protein homolog (mouse) 0.132
TRPC4 transient receptor potential cation channel, subfamily C, member 4 0.123
COL1A1 collagen, type I, alpha 1 0.121
MAPK3 mitogen-activated protein kinase 3 0.121
ABL1 c-abl oncogene 1, non-receptor tyrosine kinase 0.119
IGFBP3 insulin-like growth factor binding protein 3 0.114
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) 0.109
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha 0.109
SPTBN4 spectrin, beta, non-erythrocytic 4 0.106
PICK1 protein interacting with PRKCA 1 0.106
IGF2 insulin-like growth factor 2 (somatomedin A) 0.104
COL1A2 collagen, type I, alpha 2 0.101
AGXT2 alanine--glyoxylate aminotransferase 2 0.101
RYR2 ryanodine receptor 2 (cardiac) 0.098
PDZK1 PDZ domain containing 1 0.093
GAST gastrin 0.090
BTG2 BTG family, member 2 0.089
RB1 retinoblastoma 1 0.085
ARNT aryl hydrocarbon receptor nuclear translocator 0.083
JUND jun D proto-oncogene 0.082
UQCRB ubiquinol-cytochrome c reductase binding protein 0.078
DNM1 dynamin 1 0.077
ADAM12 ADAM metallopeptidase domain 12 0.073
FBXW7 F-box and WD repeat domain containing 7 0.070
SOCS3 suppressor of cytokine signaling 3 0.068
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 0.066
PROX1 prospero homeobox 1 0.065
RUNDC3A RUN domain containing 3A 0.064
KLF4 Kruppel-like factor 4 (gut) 0.063
GADD45B growth arrest and DNA-damage-inducible, beta 0.061
INO80B INO80 complex subunit B 0.056
CCND3 cyclin D3 0.056
BBS1 Bardet-Biedl syndrome 1 0.054
FN1 fibronectin 1 0.054
MATK megakaryocyte-associated tyrosine kinase 0.053
ATF2 activating transcription factor 2 0.053
BCR breakpoint cluster region 0.053
NEDD4 neural precursor cell expressed, developmentally down-regulated 4 0.053
SREBF2 sterol regulatory element binding transcription factor 2 0.053
RHOB ras homolog gene family, member B 0.049
CYR61 cysteine-rich, angiogenic inducer, 61 0.049
PCGF2 polycomb group ring finger 2 0.047
DUSP6 dual specificity phosphatase 6 0.046
RAPGEF2 Rap guanine nucleotide exchange factor (GEF) 2 0.046
BCL2L1 BCL2-like 1 0.046
PDGFRA platelet-derived growth factor receptor, alpha polypeptide 0.045
FOSL2 FOS-like antigen 2 0.044
KLF6 Kruppel-like factor 6 0.044
PRKCE protein kinase C, epsilon 0.042
THBS1 thrombospondin 1 0.040
CDK6 cyclin-dependent kinase 6 0.040
KSR1 kinase suppressor of ras 1 0.040
RGS2 regulator of G-protein signaling 2, 24kDa 0.040
C3orf15 chromosome 3 open reading frame 15 0.038
TIMP3 TIMP metallopeptidase inhibitor 3 0.037
AQP7 aquaporin 7 0.037
PDGFRB platelet-derived growth factor receptor, beta polypeptide 0.036
DUSP5 dual specificity phosphatase 5 0.036
DUSP1 dual specificity phosphatase 1 0.036
IGFBP5 insulin-like growth factor binding protein 5 0.034
ABI1 abl-interactor 1 0.034
SNAI1 snail homolog 1 (Drosophila) 0.034
NR0B2 nuclear receptor subfamily 0, group B, member 2 0.034
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Mus musculus
Name Description Probability Func Analog Organism
Lepr leptin receptor 0.964
Ptgs2 prostaglandin-endoperoxide synthase 2 0.935
Trp53 transformation related protein 53 0.814
Pax2 paired box gene 2 0.612
Per2 period homolog 2 (Drosophila) 0.508
Lhx1 LIM homeobox protein 1 0.488
Cry2 cryptochrome 2 (photolyase-like) 0.430
Nos3 nitric oxide synthase 3, endothelial cell 0.397
Esr1 estrogen receptor 1 (alpha) 0.353
Pten phosphatase and tensin homolog 0.330
Pax8 paired box gene 8 0.299
Nr5a1 nuclear receptor subfamily 5, group A, member 1 0.273
Ar androgen receptor 0.254
Scn5a sodium channel, voltage-gated, type V, alpha 0.242
Ret ret proto-oncogene 0.233
Lhcgr luteinizing hormone/choriogonadotropin receptor 0.209
Gdnf glial cell line derived neurotrophic factor 0.197
Egr2 early growth response 2 0.157
Ctnnb1 catenin (cadherin associated protein), beta 1 0.153
Dusp1 dual specificity phosphatase 1 0.149
Cav1 caveolin 1, caveolae protein 0.145
Pdx1 pancreatic and duodenal homeobox 1 0.133
Cebpb CCAAT/enhancer binding protein (C/EBP), beta 0.131
Lep leptin 0.115
Ppargc1a peroxisome proliferative activated receptor, gamma, coactivator 1 alpha 0.107
Kit kit oncogene 0.105
Cdkn1b cyclin-dependent kinase inhibitor 1B 0.102
Nos1 nitric oxide synthase 1, neuronal 0.097
Fos FBJ osteosarcoma oncogene 0.095
Shh sonic hedgehog 0.093
Cry1 cryptochrome 1 (photolyase-like) 0.093
Lmx1a LIM homeobox transcription factor 1 alpha 0.090
Cdk6 cyclin-dependent kinase 6 0.090
Pparg peroxisome proliferator activated receptor gamma 0.085
Per1 period homolog 1 (Drosophila) 0.083
Col4a3 collagen, type IV, alpha 3 0.082
Vhl von Hippel-Lindau tumor suppressor 0.081
Amhr2 anti-Mullerian hormone type 2 receptor 0.080
Stat3 signal transducer and activator of transcription 3 0.079
Emx2 empty spiracles homolog 2 (Drosophila) 0.077
Atf3 activating transcription factor 3 0.074
Slc4a4 solute carrier family 4 (anion exchanger), member 4 0.074
Apc adenomatosis polyposis coli 0.072
Nr4a1 nuclear receptor subfamily 4, group A, member 1 0.071
Ghr growth hormone receptor 0.071
Dkk1 dickkopf homolog 1 (Xenopus laevis) 0.071
Cyr61 cysteine rich protein 61 0.065
Vdr vitamin D receptor 0.064
Tbx5 T-box 5 0.063
Fgfr2 fibroblast growth factor receptor 2 0.059
Drd2 dopamine receptor D2 0.057
Wt1 Wilms tumor 1 homolog 0.057
Esr2 estrogen receptor 2 (beta) 0.057
Egr1 early growth response 1 0.057
Ttn titin 0.055
Usp2 ubiquitin specific peptidase 2 0.053
Adra1b adrenergic receptor, alpha 1b 0.051
Lhx3 LIM homeobox protein 3 0.050
Crim1 cysteine rich transmembrane BMP regulator 1 (chordin like) 0.050
Thrb thyroid hormone receptor beta 0.049
Irs2 insulin receptor substrate 2 0.048
Kras v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog 0.047
Mybpc3 myosin binding protein C, cardiac 0.045
LOC100503041 PDZ domain-containing protein 7-like 0.045
Cftr cystic fibrosis transmembrane conductance regulator homolog 0.044
Plau plasminogen activator, urokinase 0.043
Arntl aryl hydrocarbon receptor nuclear translocator-like 0.038
Clock circadian locomotor output cycles kaput 0.038
Siah2 seven in absentia 2 0.037
Csf1 colony stimulating factor 1 (macrophage) 0.035
Ror2 receptor tyrosine kinase-like orphan receptor 2 0.035
Hsd11b2 hydroxysteroid 11-beta dehydrogenase 2 0.034
Junb Jun-B oncogene 0.034
Rarb retinoic acid receptor, beta 0.034
Apoe apolipoprotein E 0.034
Agtr2 angiotensin II receptor, type 2 0.033
Gata6 GATA binding protein 6 0.032
Kl klotho 0.032
Htt huntingtin 0.031
Kiss1 KiSS-1 metastasis-suppressor 0.030
Gpr50 G-protein-coupled receptor 50 0.030
Gata4 GATA binding protein 4 0.030
Ccne1 cyclin E1 0.030
Ppara peroxisome proliferator activated receptor alpha 0.030
Kcnn1 potassium intermediate/small conductance calcium-activated channel, subfamily N, member 1 0.030
Bmp7 bone morphogenetic protein 7 0.029
Jun Jun oncogene 0.029
Fgfr1 fibroblast growth factor receptor 1 0.029
Ihh Indian hedgehog 0.028
Mc1r melanocortin 1 receptor 0.028
Tal1 T-cell acute lymphocytic leukemia 1 0.028
Cdkn1a cyclin-dependent kinase inhibitor 1A (P21) 0.026
Otx1 orthodenticle homolog 1 (Drosophila) 0.026
Ptpn11 protein tyrosine phosphatase, non-receptor type 11 0.025
Csnk1e casein kinase 1, epsilon 0.024
Prlr prolactin receptor 0.024
Ptpru protein tyrosine phosphatase, receptor type, U 0.024
Rarg retinoic acid receptor, gamma 0.024
Fshr follicle stimulating hormone receptor 0.024
Osr1 odd-skipped related 1 (Drosophila) 0.023
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism