The network for 'macromolecular complex subunit organization' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

macromolecular complex subunit organization

Any process in which macromolecules aggregate, disaggregate, or are modified, resulting in the formation, disassembly, or alteration of a macromolecular complex.

Name Description Probability Func Analog Organism
Tagln2 transgelin 2 0.758
Dlgap1 discs, large (Drosophila) homolog-associated protein 1 0.727
Plek pleckstrin 0.725
Ywhab tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide 0.722
Cap1 CAP, adenylate cyclase-associated protein 1 (yeast) 0.703
Hsp90b1 heat shock protein 90, beta, member 1 0.692
Il12b interleukin 12B 0.684
Htr2c 5-hydroxytryptamine (serotonin) receptor 2C 0.651
Hsp90aa1 heat shock protein 90, alpha (cytosolic), class A member 1 0.633
Vcp valosin-containing protein 0.633
Casp2 caspase 2 0.616
Magi2 membrane associated guanylate kinase, WW and PDZ domain containing 2 0.608
Efhd2 EF-hand domain family, member D2 0.607
Cltc clathrin, heavy chain (Hc) 0.602
Gad2 glutamate decarboxylase 2 0.593
Flna filamin A, alpha 0.590
Tpm3 tropomyosin 3, gamma 0.583
Nefl neurofilament, light polypeptide 0.582
Mgp matrix Gla protein 0.578
Rbbp7 retinoblastoma binding protein 7 0.566
Arpc1b actin related protein 2/3 complex, subunit 1B 0.556
Taok1 TAO kinase 1 0.556
Atp1a1 ATPase, Na+/K+ transporting, alpha 1 polypeptide 0.551
Col3a1 collagen, type III, alpha 1 0.537
Slc2a4 solute carrier family 2 (facilitated glucose transporter), member 4 0.535
Eif3m eukaryotic translation initiation factor 3, subunit M 0.534
Dnaja2 DnaJ (Hsp40) homolog, subfamily A, member 2 0.533
Hbb hemoglobin, beta 0.527
Alas2 aminolevulinate, delta-, synthase 2 0.522
Gng7 guanine nucleotide binding protein (G protein), gamma 7 0.517
Chrna7 cholinergic receptor, nicotinic, alpha 7 0.511
Flnb filamin, beta 0.509
Stip1 stress-induced phosphoprotein 1 0.503
Hsp90ab1 heat shock protein 90 alpha (cytosolic), class B member 1 0.489
Met met proto-oncogene 0.489
Gnb2l1 guanine nucleotide binding protein (G protein), beta polypeptide 2 like 1 0.487
Col1a1 collagen, type I, alpha 1 0.485
Fkbp4 FK506 binding protein 4 0.484
Myh3 myosin, heavy chain 3, skeletal muscle, embryonic 0.483
Cct4 chaperonin containing Tcp1, subunit 4 (delta) 0.482
Gpx1 glutathione peroxidase 1 0.446
Itgb1 integrin, beta 1 0.441
Gabrg1 gamma-aminobutyric acid (GABA) A receptor, gamma 1 0.435
Cast calpastatin 0.431
Dync1h1 dynein cytoplasmic 1 heavy chain 1 0.427
Rabggtb Rab geranylgeranyltransferase, beta subunit 0.423
Kcnj15 potassium inwardly-rectifying channel, subfamily J, member 15 0.418
Lyz2 lysozyme 2 0.417
Npy1r neuropeptide Y receptor Y1 0.414
Grin2b glutamate receptor, ionotropic, N-methyl D-aspartate 2B 0.414
Mpp2 membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2) 0.413
Cnbp CCHC-type zinc finger, nucleic acid binding protein 0.410
Ahnak AHNAK nucleoprotein 0.406
LOC24906 RoBo-1 0.404
Pak2 p21 protein (Cdc42/Rac)-activated kinase 2 0.402
Wdr1 WD repeat domain 1 0.401
Psmc2 proteasome (prosome, macropain) 26S subunit, ATPase 2 0.398
Cand1 cullin-associated and neddylation-dissociated 1 0.395
Dnm1l dynamin 1-like 0.392
Vav1 vav 1 guanine nucleotide exchange factor 0.391
Grin1 glutamate receptor, ionotropic, N-methyl D-aspartate 1 0.391
Serpinh1 serine (or cysteine) peptidase inhibitor, clade H, member 1 0.387
Hba-a2 hemoglobin alpha, adult chain 2 0.386
Hspe1 heat shock protein 1 (chaperonin 10) 0.385
Tap2 transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) 0.385
Actc1 actin, alpha, cardiac muscle 1 0.384
Slc22a25 solute carrier family 22, member 25 0.382
Rpl18 ribosomal protein L18 0.381
Ywhaz tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide 0.380
Anapc5 anaphase-promoting complex subunit 5 0.379
Sdc3 syndecan 3 0.378
Col12a1 collagen, type XII, alpha 1 0.377
Gzmk granzyme K 0.368
Tubb5 tubulin, beta 5 0.367
Ccl4 chemokine (C-C motif) ligand 4 0.364
Jak2 Janus kinase 2 0.364
Gip gastric inhibitory polypeptide 0.363
Xpo1 exportin 1, CRM1 homolog (yeast) 0.361
Myo1b myosin Ib 0.355
St8sia3 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3 0.355
Ran RAN, member RAS oncogene family 0.355
Lyn v-yes-1 Yamaguchi sarcoma viral related oncogene homolog 0.352
Csf2rb colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) 0.351
Map1a microtubule-associated protein 1A 0.349
Ccbp2 chemokine binding protein 2 0.348
Socs5 suppressor of cytokine signaling 5 0.348
Cd53 Cd53 molecule 0.345
Tmpo thymopoietin 0.344
Map2 microtubule-associated protein 2 0.344
Hspd1 heat shock protein 1 (chaperonin) 0.343
Gria2 glutamate receptor, ionotropic, AMPA 2 0.343
Pfn1 profilin 1 0.341
Rhcg Rh family, C glycoprotein 0.340
Cct3 chaperonin containing Tcp1, subunit 3 (gamma) 0.338
Gfra2 GDNF family receptor alpha 2 0.337
Kpnb1 karyopherin (importin) beta 1 0.337
Rplp0 ribosomal protein, large, P0 0.336
Tpm4 tropomyosin 4 0.335
Cplx1 complexin 1 0.335
Gja6 gap junction protein, alpha 6 0.335
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
tag-232 Protein TAG-232 0.725
rps-3 Protein RPS-3 0.665
pqn-59 Protein PQN-59 0.651
rpl-38 Protein RPL-38 0.587
lmn-1 Protein LMN-1 0.572
nhr-2 Protein NHR-2 0.568
K07C5.4 Protein K07C5.4 0.530
prp-8 Protein PRP-8 0.527
npp-19 Protein NPP-19 0.526
mat-3 Protein MAT-3 0.514
acs-4 Protein ACS-4 0.513
pkg-1 Protein PKG-1 0.503
npp-7 Protein NPP-7 0.501
hsp-1 Protein HSP-1 0.491
rpl-6 Protein RPL-6 0.476
rps-0 Protein RPS-0 0.455
eat-6 Protein EAT-6 0.447
rpl-18 Protein RPL-18 0.436
his-5 Protein HIS-5 0.435
his-64 Protein HIS-64 0.432
sma-6 Protein SMA-6 0.423
rpl-15 Protein RPL-15 0.423
spc-1 Protein SPC-1 0.421
rpt-5 Protein RPT-5 0.418
rpl-3 Protein RPL-3 0.411
rpl-4 Protein RPL-4 0.400
ran-1 Protein RAN-1 0.398
cks-1 Protein CKS-1 0.397
R11A8.7 Protein R11A8.7 0.397
rpl-30 Protein RPL-30 0.389
T28D9.1 Protein T28D9.1 0.383
let-502 Protein LET-502 0.380
rpl-19 Protein RPL-19 0.380
M03F8.3 Protein M03F8.3 0.373
madd-4 Protein MADD-4 0.364
jnk-1 Protein JNK-1 0.359
mig-5 Protein MIG-5 0.358
C53B4.4 Protein C53B4.4 0.357
unc-9 Protein UNC-9 0.349
fem-2 Protein FEM-2 0.348
hcp-6 Protein HCP-6 0.348
vav-1 Protein VAV-1 0.348
mbk-1 Protein MBK-1 0.348
his-1 Protein HIS-1 0.347
pbrm-1 Protein PBRM-1 0.342
ZC395.10 Protein ZC395.10 0.338
cpna-3 Protein CPNA-3 0.338
asd-1 Protein ASD-1 0.337
klp-19 Protein KLP-19 0.334
zyg-9 Protein ZYG-9 0.333
CELE_C08H9.2 Protein C08H9.2 0.332
spd-5 Protein SPD-5 0.331
gon-4 Protein GON-4 0.329
adr-1 Protein ADR-1 0.327
rpn-3 Protein RPN-3 0.327
rpa-2 Protein RPA-2 0.327
rps-1 Protein RPS-1 0.326
R90.1 Protein R90.1 0.325
rad-26 Protein RAD-26 0.325
D1081.8 Protein D1081.8 0.324
eef-1A.1 Protein EEF-1A.1 0.323
cfim-2 Protein CFIM-2 0.323
cdc-42 Protein CDC-42 0.322
mix-1 Protein MIX-1 0.320
npl-4.2 Protein NPL-4.2 0.320
ppw-2 Protein PPW-2 0.320
unc-6 Protein UNC-6 0.318
ztf-7 Protein ZTF-7 0.318
gpr-2 Protein GPR-2 0.314
nmy-2 Protein NMY-2 0.314
emb-5 Protein EMB-5 0.313
rpl-11.1 Protein RPL-11.1 0.312
cam-1 Protein CAM-1 0.312
tag-163 Protein TAG-163 0.310
sid-1 Protein SID-1 0.308
F58E10.3 Protein F58E10.3 0.307
rpl-5 Protein RPL-5 0.306
sli-1 Protein SLI-1 0.306
pry-1 Protein PRY-1 0.305
unc-112 Protein UNC-112 0.305
unc-60 Protein UNC-60 0.301
goa-1 Protein GOA-1 0.300
twk-18 Protein TWK-18 0.300
C37A2.7 Protein C37A2.7 0.300
T22C1.1 Protein T22C1.1 0.298
aly-3 Protein ALY-3 0.298
pas-4 Protein PAS-4 0.297
kle-2 Protein KLE-2 0.294
dnj-11 Protein DNJ-11 0.293
egl-8 Protein EGL-8 0.292
CELE_C24H12.5 Protein C24H12.5 0.291
H43I07.2 Protein H43I07.2 0.291
nap-1 Protein NAP-1 0.289
rsa-1 Protein RSA-1 0.288
bub-1 Protein BUB-1 0.286
egg-6 Protein EGG-6 0.285
rpl-28 Protein RPL-28 0.284
rpl-14 Protein RPL-14 0.283
csn-1 Protein CSN-1 0.282
rpl-24.1 Protein RPL-24.1 0.282
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Danio rerio
Name Description Probability Func Analog Organism
cx43 connexin 43 0.658
ptch2 patched 2 0.654
gli1 GLI-Kruppel family member 1 0.651
efnb2a ephrin B2a 0.630
ikzf1 IKAROS family zinc finger 1 (Ikaros) 0.591
mga MAX gene associated 0.582
cmyb transcription factor cmyb 0.574
nrp1a neuropilin 1a 0.571
myod1 myogenic differentiation 1 0.498
rps7 ribosomal protein S7 0.489
pbx4 pre-B-cell leukemia transcription factor 4 0.462
rpl7 ribosomal protein L7 0.459
ran ras-related nuclear protein 0.453
rps8a ribosomal protein S8a 0.436
bmp2b bone morphogenetic protein 2b 0.408
ptpra protein tyrosine phosphatase, receptor type, A 0.401
fabp3 fatty acid binding protein 3, muscle and heart 0.393
gro1 groucho 1 0.377
mafba v-maf musculoaponeurotic fibrosarcoma oncogene family, protein B (avian) 0.375
myog myogenin 0.364
tal1 T-cell acute lymphocytic leukemia 1 0.361
rps18 ribosomal protein S18 0.359
sass6 spindle assembly 6 homolog (C. elegans) 0.351
mib mind bomb 0.347
rps3a ribosomal protein S3A 0.334
myl9l myosin, light polypeptide 9, like 0.328
runx1 runt-related transcription factor 1 0.325
rpl35 ribosomal protein L35 0.321
lama1 laminin, alpha 1 0.317
pkd2 polycystic kidney disease 2 0.316
fn1 fibronectin 1 0.305
rpl19 ribosomal protein L19 0.305
nop58 NOP58 ribonucleoprotein homolog (yeast) 0.301
tac1 tachykinin 1 0.298
unc45a unc-45 homolog A (C. elegans) 0.293
wnt11r wingless-type MMTV integration site family, member 11, related 0.289
gata5 GATA-binding protein 5 0.285
fras1 Fraser syndrome 1 0.284
bmp4 bone morphogenetic protein 4 0.284
desma desmin a 0.280
rpl13 ribosomal protein L13 0.277
epb41l5 erythrocyte membrane protein band 4.1 like 5 0.272
s100a10b S100 calcium binding protein A10b 0.272
aurka aurora kinase A 0.270
col12a1 collagen, type XII, alpha 1 0.265
ift88 intraflagellar transport 88 homolog 0.264
actn1 actinin, alpha 1 0.260
mylz2 myosin, light polypeptide 2, skeletal muscle 0.258
pabpc1a poly A binding protein, cytoplasmic 1 a 0.257
zgc:101761 zgc:101761 0.250
trim33 tripartite motif-containing 33 0.249
zgc:100838 zgc:100838 0.244
slc1a2b solute carrier family 1 (glial high affinity glutamate transporter), member 2b 0.242
mmp2 matrix metalloproteinase 2 0.239
cdc42 cell division cycle 42 0.235
ssrp1a structure specific recognition protein 1a 0.233
ptmab prothymosin, alpha b 0.233
rpl36a ribosomal protein L36A 0.232
flot2a flotillin 2a 0.231
cxcr4a chemokine (C-X-C motif) receptor 4a 0.230
zbtb4 zinc finger and BTB domain containing 4 0.214
ahctf1 AT hook containing transcription factor 1 0.214
tgfb1a transforming growth factor, beta 1a 0.212
arpc5a actin related protein 2/3 complex, subunit 5A 0.207
rps5 ribosomal protein S5 0.202
atoh7 atonal homolog 7 0.202
trpv6 transient receptor potential cation channel, subfamily V, member 6 0.202
tp53 tumor protein p53 0.199
bambia BMP and activin membrane-bound inhibitor (Xenopus laevis) homolog a 0.199
psma8 proteasome (prosome, macropain) subunit, alpha type, 8 0.195
lamc1 laminin, gamma 1 0.192
spint1a serine peptidase inhibitor, Kunitz type 1 a 0.190
sumo3a SMT3 suppressor of mif two 3 homolog 3a 0.187
ppp1r12a protein phosphatase 1, regulatory (inhibitor) subunit 12A 0.185
mcmbp minichromosome maintenance complex binding protein 0.185
sf3b1 splicing factor 3b, subunit 1 0.183
runx2b runt-related transcription factor 2b 0.180
tagln2 transgelin 2 0.178
snrpc small nuclear ribonucleoprotein polypeptide C 0.177
pcbp2 poly(rC) binding protein 2 0.177
plcg1 phospholipase C, gamma 1 0.176
prpf8 pre-mRNA processing factor 8 0.171
cct7 chaperonin containing TCP1, subunit 7 (eta) 0.171
smad7 MAD, mothers against decapentaplegic homolog 7 (Drosophila) 0.169
ruvbl2 RuvB-like 2 (E. coli) 0.169
eif5a2 eukaryotic translation initiation factor 5A2 0.167
tp73 tumor protein p73 0.167
alas2 aminolevulinate, delta-, synthetase 2 0.165
pink1 PTEN induced putative kinase 1 0.164
rps15 ribosomal protein S15 0.162
kdrl kinase insert domain receptor like 0.162
lmx1b.1 LIM homeobox transcription factor 1, beta 1 0.162
rps29 ribosomal protein S29 0.160
slc2a11l solute carrier family 2 (facilitated glucose transporter), member 11-like 0.159
igfbp3 insulin-like growth factor binding protein 3 0.158
pafah1b1b platelet-activating factor acetylhydrolase, isoform Ib, alpha subunit b 0.158
sod1 superoxide dismutase 1, soluble 0.158
bcl2l10 BCL2-like 10 (apoptosis facilitator) 0.157
crabp2a cellular retinoic acid binding protein 2, a 0.155
evx1 even-skipped homeobox 1 0.154
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Drosophila melanogaster
Name Description Probability Func Analog Organism
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Homo sapiens
Name Description Probability Func Analog Organism
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Mus musculus
Name Description Probability Func Analog Organism
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism