The network for 'organ regeneration' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

organ regeneration

The regrowth of a lost or destroyed organ.

Rattus norvegicus
Name Description Probability Func Analog Organism
Gc group specific component 0.587
Cav1 caveolin 1, caveolae protein 0.579
Slc10a1 solute carrier family 10 (sodium/bile acid cotransporter family), member 1 0.564
Cyp2c23 cytochrome P450, family 2, subfamily c, polypeptide 23 0.547
Gnmt glycine N-methyltransferase 0.530
Pzp pregnancy-zone protein 0.512
Pdk4 pyruvate dehydrogenase kinase, isozyme 4 0.468
Mug1 murinoglobulin 1 0.462
Ahsg alpha-2-HS-glycoprotein 0.429
RT1-EC2 RT1 class Ib, locus EC2 0.404
Socs2 suppressor of cytokine signaling 2 0.399
Fga fibrinogen alpha chain 0.392
Ugt1a7c UDP glucuronosyltransferase 1 family, polypeptide A7C 0.355
Met met proto-oncogene 0.352
Azgp1 alpha-2-glycoprotein 1, zinc-binding 0.347
Serpina1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 0.342
Gpr116 G protein-coupled receptor 116 0.341
Adam7 ADAM metallopeptidase domain 7 0.335
Hp haptoglobin 0.329
Fgfr2 fibroblast growth factor receptor 2 0.316
Emcn endomucin 0.314
Cxcl10 chemokine (C-X-C motif) ligand 10 0.314
Nr4a3 nuclear receptor subfamily 4, group A, member 3 0.306
Twist2 twist homolog 2 (Drosophila) 0.297
Smad7 SMAD family member 7 0.287
Dnase1l3 deoxyribonuclease 1-like 3 0.283
Ppp1r3b protein phosphatase 1, regulatory (inhibitor) subunit 3B 0.278
Alb albumin 0.276
Cpb2 carboxypeptidase B2 (plasma) 0.269
Aldob aldolase B, fructose-bisphosphate 0.262
Utrn utrophin 0.259
LOC100361547 Cytochrome P450, family 2, subfamily c, polypeptide 7-like 0.255
Fabp1 fatty acid binding protein 1, liver 0.248
Sult1b1 sulfotransferase family, cytosolic, 1B, member 1 0.237
Ambp alpha-1-microglobulin/bikunin precursor 0.236
Akr1c14 aldo-keto reductase family 1, member C14 0.233
Hsd3b6 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 6 0.227
Mgst1 microsomal glutathione S-transferase 1 0.226
Rara retinoic acid receptor, alpha 0.226
Prlr prolactin receptor 0.225
Tek TEK tyrosine kinase, endothelial 0.215
Cdkn2b cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4) 0.213
Gabrp gamma-aminobutyric acid (GABA-A) receptor, pi 0.211
Apoa5 apolipoprotein A-V 0.209
Lmna lamin A 0.206
Apoh apolipoprotein H (beta-2-glycoprotein I) 0.206
Ucp3 uncoupling protein 3 (mitochondrial, proton carrier) 0.204
Efnb1 ephrin B1 0.204
Mcpt3 mast cell peptidase 3 0.203
Cd4 Cd4 molecule 0.199
Cd14 CD14 molecule 0.196
Agtr1a angiotensin II receptor, type 1a 0.193
Kdr kinase insert domain receptor 0.190
Serpind1 serpin peptidase inhibitor, clade D (heparin cofactor), member 1 0.190
Itih4 inter alpha-trypsin inhibitor, heavy chain 4 0.183
Icam1 intercellular adhesion molecule 1 0.182
Ces1c carboxylesterase 1C 0.180
Apoa2 apolipoprotein A-II 0.179
Anpep alanyl (membrane) aminopeptidase 0.178
Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 0.177
Prrx1 paired related homeobox 1 0.175
LOC100364500 RT1 class I, locus CE11-like 0.173
RGD1564865 similar to 20-alpha-hydroxysteroid dehydrogenase 0.173
Gucy2d guanylate cyclase 2d 0.170
Plg plasminogen 0.170
Cd9 CD9 molecule 0.168
Rup2 urinary protein 2 0.168
Cd68 Cd68 molecule 0.165
Plau plasminogen activator, urokinase 0.165
Mef2d myocyte enhancer factor 2D 0.164
Apcs amyloid P component, serum 0.161
Cps1 carbamoyl-phosphate synthetase 1 0.161
Synpo synaptopodin 0.160
Ugt2b5 UDP glucuronosyltransferase 2 family, polypeptide B5 0.154
Gucy2f guanylate cyclase 2F 0.151
Hpx hemopexin 0.149
Bcl2 B-cell CLL/lymphoma 2 0.148
LOC100362824 caveolin 2-like 0.146
C1qc complement component 1, q subcomponent, C chain 0.145
Il5 interleukin 5 0.145
Capn2 calpain 2 0.144
Anxa4 annexin A4 0.143
Agxt2 alanine-glyoxylate aminotransferase 2 0.140
LOC293989 cytochrome P450-like 0.135
Serpine1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 0.133
Ugt2b36 UDP glucuronosyltransferase 2 family, polypeptide B36 0.133
Mgat5 mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase 0.131
Slco2a1 solute carrier organic anion transporter family, member 2a1 0.131
Gbp2 guanylate binding protein 2 0.131
Mgst2 microsomal glutathione S-transferase 2 0.131
Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 0.130
Musk muscle, skeletal, receptor tyrosine kinase 0.127
Ugt1a6 UDP glucuronosyltransferase 1 family, polypeptide A6 0.126
Ptch1 patched homolog 1 (Drosophila) 0.126
Serpina3k serine (or cysteine) peptidase inhibitor, clade A, member 3K 0.125
Hspb2 heat shock protein beta 2 0.123
Olr1530 olfactory receptor 1530 0.123
Ngf nerve growth factor (beta polypeptide) 0.122
Cartpt CART prepropeptide 0.120
Serpinb9 serpin peptidase inhibitor, clade B (ovalbumin), member 9 0.118
Loading network...
Caenorhabditis elegans
Name Description Probability Func Analog Organism
Loading network...
Danio rerio
Name Description Probability Func Analog Organism
cmyb transcription factor cmyb 0.351
notch3 notch homolog 3 0.158
chaf1b chromatin assembly factor 1, subunit B 0.074
crb2a crumbs homolog 2a 0.063
jag1a jagged 1a 0.063
junb jun B proto-oncogene 0.049
egr1 early growth response 1 0.046
atf3 activating transcription factor 3 0.046
atoh7 atonal homolog 7 0.045
tert telomerase reverse transcriptase 0.043
socs3a suppressor of cytokine signaling 3a 0.042
copeb core promoter element binding protein 0.040
flt4 fms-related tyrosine kinase 4 0.039
gapdhs glyceraldehyde-3-phosphate dehydrogenase, spermatogenic 0.039
pcna proliferating cell nuclear antigen 0.037
fli1a friend leukemia integration 1a 0.036
flt1 fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) 0.036
stat3 signal transduction and activation of transcription 3 0.035
zgc:153997 zgc:153997 0.033
slit3 slit (Drosophila) homolog 3 0.033
mib mind bomb 0.031
il6st interleukin 6 signal transducer 0.031
aldocb aldolase C, fructose-bisphosphate, b 0.031
antxr1 anthrax toxin receptor 1 0.030
dlc deltaC 0.029
mitfa microphthalmia-associated transcription factor a 0.029
mcm5 MCM5 minichromosome maintenance deficient 5 (S. cerevisiae) 0.029
cahz carbonic anhydrase 0.029
met met proto-oncogene (hepatocyte growth factor receptor) 0.029
hlx1 H2.0-like homeo box 1 (Drosophila) 0.028
duox dual oxidase 0.028
ahr2 aryl hydrocarbon receptor 2 0.028
col4a5 collagen, type IV, alpha 5 (Alport syndrome) 0.027
si:dkey-228g21.4 si:dkey-228g21.4 0.026
efnb2a ephrin B2a 0.026
fabp11a fatty acid binding protein 11a 0.026
gdf6a growth differentiation factor 6a 0.026
tnfrsfa tumor necrosis factor receptor superfamily, member a 0.026
scube2 signal peptide, CUB domain, EGF-like 2 0.026
urod uroporphyrinogen decarboxylase 0.025
socs3b suppressor of cytokine signaling 3b 0.025
lama4 laminin, alpha 4 0.024
plekhh1 pleckstrin homology domain containing, family H (with MyTH4 domain) member 1 0.024
igf2b insulin-like growth factor 2b 0.023
dnmt8 DNA (cytosine-5-)-methyltransferase 8 0.023
zgc:171553 zgc:171553 0.023
LOC554173 abnormal spindles 0.023
dctn1a dynactin 1a 0.022
igfbp7 insulin-like growth factor binding protein 7 0.022
prdm5 PR domain containing 5 0.022
nfe2 nuclear factor, erythroid-derived 2 0.021
aqp8a.1 aquaporin 8a, tandem duplicate 1 0.021
ephb4a eph receptor B4a 0.021
mybl2 myeloblastosis oncogene-like 2 0.021
rad21 RAD21 homolog (S. pombe) 0.021
gas6 growth arrest-specific 6 0.020
epas1b endothelial PAS domain protein 1b 0.020
si:rp71-39b20.7 si:rp71-39b20.7 0.020
zgc:103710 zgc:103710 0.020
pacsin3 protein kinase C and casein kinase substrate in neurons 3 0.020
zgc:100919 zgc:100919 0.020
LOC100534970 hypothetical protein LOC100534970 0.019
LOC555482 tachykinin receptor 3-like 0.019
tshz2 teashirt zinc finger homeobox 2 0.019
fosl2 fos-like antigen 2 0.019
prom1a prominin 1a 0.019
fos v-fos FBJ murine osteosarcoma viral oncogene homolog 0.019
tnfrsf1a tumor necrosis factor receptor superfamily, member 1a 0.019
kdr kinase insert domain receptor (a type III receptor tyrosine kinase) 0.019
ctsl1a cathepsin L, 1 a 0.019
sat1a spermidine/spermine N1-acetyltransferase 1a 0.019
lpp LIM domain containing preferred translocation partner in lipoma 0.018
mef2a myocyte enhancer factor 2a 0.018
slc17a7 solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 7 0.018
fgf10a fibroblast growth factor 10a 0.018
uchl1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) 0.018
si:dkey-76b14.4 si:dkey-76b14.4 0.018
igfbp1a insulin-like growth factor binding protein 1a 0.018
efnb3b ephrin B3b 0.018
mcm6 MCM6 minichromosome maintenance deficient 6, mitotin (S. cerevisiae) 0.018
cdipt CDP-diacylglycerol--inositol 3-phosphatidyltransferase (phosphatidylinositol synthase) 0.018
celsr3 cadherin, EGF LAG seven-pass G-type receptor 3 0.017
gtf2h4 general transcription factor IIH, polypeptide 4 0.017
hmga1a high mobility group AT-hook 1a 0.017
lmna lamin A 0.017
chrm2a cholinergic receptor, muscarinic 2a 0.017
eno1 enolase 1, (alpha) 0.017
fabp2 fatty acid binding protein 2, intestinal 0.017
slc9a8 solute carrier family 9 (sodium/hydrogen exchanger), member 8 0.017
hoxd3a homeo box D3a 0.017
si:dkeyp-104h9.6 si:dkeyp-104h9.6 0.017
zgc:158643 zgc:158643 0.017
itga5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide) 0.017
igf1ra insulin-like growth factor 1a receptor 0.017
mcl1b myeloid cell leukemia sequence 1b 0.017
tal1 T-cell acute lymphocytic leukemia 1 0.017
aldh1a3 aldehyde dehydrogenase 1 family, member A3 0.016
jak1 Janus kinase 1 0.016
nr1i2 nuclear receptor subfamily 1, group I, member 2 0.016
rspo1 R-spondin homolog (Xenopus laevis) 0.016
Loading network...
Drosophila melanogaster
Name Description Probability Func Analog Organism
Loading network...
Homo sapiens
Name Description Probability Func Analog Organism
Loading network...
Mus musculus
Name Description Probability Func Analog Organism
Lyz2 lysozyme 2 0.966
Cdk2 cyclin-dependent kinase 2 0.837
Il6st interleukin 6 signal transducer 0.823
Ptpn11 protein tyrosine phosphatase, non-receptor type 11 0.763
Cd19 CD19 antigen 0.516
1100001G20Rik RIKEN cDNA 1100001G20 gene 0.508
Cdkn1b cyclin-dependent kinase inhibitor 1B 0.503
Nfkb2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100 0.465
Lepr leptin receptor 0.464
Cdk4 cyclin-dependent kinase 4 0.444
Agtr1a angiotensin II receptor, type 1a 0.440
Egfr epidermal growth factor receptor 0.430
Jak2 Janus kinase 2 0.385
Notch2 Notch gene homolog 2 (Drosophila) 0.385
Trp53 transformation related protein 53 0.378
Shc1 src homology 2 domain-containing transforming protein C1 0.342
Gab2 growth factor receptor bound protein 2-associated protein 2 0.316
Grb2 growth factor receptor bound protein 2 0.300
Stat3 signal transducer and activator of transcription 3 0.275
Ifng interferon gamma 0.263
Pparg peroxisome proliferator activated receptor gamma 0.262
Tgfbr2 transforming growth factor, beta receptor II 0.242
Apoe apolipoprotein E 0.237
Ccne1 cyclin E1 0.225
Smad3 MAD homolog 3 (Drosophila) 0.195
Myb myeloblastosis oncogene 0.186
Tcf7 transcription factor 7, T-cell specific 0.182
Socs1 suppressor of cytokine signaling 1 0.169
Fgfr2 fibroblast growth factor receptor 2 0.162
Il6 interleukin 6 0.161
Cdh5 cadherin 5 0.156
Pnpla2 patatin-like phospholipase domain containing 2 0.156
Ccnb2 cyclin B2 0.155
ND6 NADH dehydrogenase subunit 6 0.151
Wrn Werner syndrome homolog (human) 0.145
Rbpj recombination signal binding protein for immunoglobulin kappa J region 0.142
Csf1 colony stimulating factor 1 (macrophage) 0.136
Hist1h1a histone cluster 1, H1a 0.127
Ccna2 cyclin A2 0.125
Hes1 hairy and enhancer of split 1 (Drosophila) 0.121
Cebpa CCAAT/enhancer binding protein (C/EBP), alpha 0.121
Slc40a1 solute carrier family 40 (iron-regulated transporter), member 1 0.117
Nasp nuclear autoantigenic sperm protein (histone-binding) 0.112
Nos3 nitric oxide synthase 3, endothelial cell 0.112
Cdk6 cyclin-dependent kinase 6 0.111
Adrb3 adrenergic receptor, beta 3 0.111
F10 coagulation factor X 0.102
Vav3 vav 3 oncogene 0.098
Cav1 caveolin 1, caveolae protein 0.097
Ldlr low density lipoprotein receptor 0.096
Uchl1 ubiquitin carboxy-terminal hydrolase L1 0.093
Tal1 T-cell acute lymphocytic leukemia 1 0.083
Acvrl1 activin A receptor, type II-like 1 0.081
Kng1 kininogen 1 0.079
Ccne2 cyclin E2 0.079
Adrb1 adrenergic receptor, beta 1 0.078
Esr1 estrogen receptor 1 (alpha) 0.078
Orm2 orosomucoid 2 0.077
Ren1 renin 1 structural 0.077
Stat6 signal transducer and activator of transcription 6 0.076
Atp7a ATPase, Cu++ transporting, alpha polypeptide 0.076
Ghr growth hormone receptor 0.075
Il1r1 interleukin 1 receptor, type I 0.072
Cp ceruloplasmin 0.072
Tpm4 tropomyosin 4 0.069
Serpina3n serine (or cysteine) peptidase inhibitor, clade A, member 3N 0.068
Foxp3 forkhead box P3 0.068
Orm3 orosomucoid 3 0.066
Tgfbr1 transforming growth factor, beta receptor I 0.066
Sirt1 sirtuin 1 (silent mating type information regulation 2, homolog) 1 (S. cerevisiae) 0.065
Dll1 delta-like 1 (Drosophila) 0.064
Slc7a2 solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 0.063
Nr3c1 nuclear receptor subfamily 3, group C, member 1 0.063
Vcan versican 0.063
Crp C-reactive protein, pentraxin-related 0.061
Lbp lipopolysaccharide binding protein 0.061
Cyld cylindromatosis (turban tumor syndrome) 0.061
Adam17 a disintegrin and metallopeptidase domain 17 0.060
Lrg1 leucine-rich alpha-2-glycoprotein 1 0.060
Serpina10 serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10 0.060
Acvr1 activin A receptor, type 1 0.059
Sox2 SRY-box containing gene 2 0.058
Hamp hepcidin antimicrobial peptide 0.058
Pcna proliferating cell nuclear antigen 0.058
H1 histocompatibility 1 0.057
F9 coagulation factor IX 0.056
Serpina3m serine (or cysteine) peptidase inhibitor, clade A, member 3M 0.056
Agpat2 1-acylglycerol-3-phosphate O-acyltransferase 2 (lysophosphatidic acid acyltransferase, beta) 0.056
Bdkrb2 bradykinin receptor, beta 2 0.056
Vav2 vav 2 oncogene 0.056
Tgfb2 transforming growth factor, beta 2 0.055
Pten phosphatase and tensin homolog 0.054
Pax2 paired box gene 2 0.053
Foxf1a forkhead box F1a 0.053
Tgfbr3 transforming growth factor, beta receptor III 0.053
Hdac1 histone deacetylase 1 0.051
Mrap melanocortin 2 receptor accessory protein 0.051
Rara retinoic acid receptor, alpha 0.051
Pim1 proviral integration site 1 0.051
Pck1 phosphoenolpyruvate carboxykinase 1, cytosolic 0.050
Loading network...
Saccharomyces cerevisiae
Name Description Probability Func Analog Organism