The network for 'myeloid leukocyte mediated immunity' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

myeloid leukocyte mediated immunity

Any process involved in the carrying out of an immune response by a myeloid leukocyte.

Rattus norvegicus
Name Description Probability Func Analog Organism
Ywhag tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide 0.541
Ywhaz tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide 0.506
Morf4l2 mortality factor 4 like 2 0.332
Hck hemopoietic cell kinase 0.244
Ywhab tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide 0.242
Ptprc protein tyrosine phosphatase, receptor type, C 0.159
Calm1 calmodulin 1 0.157
Actr3 ARP3 actin-related protein 3 homolog (yeast) 0.147
Ptpn18 protein tyrosine phosphatase, non-receptor type 18 0.128
Ywhae tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide 0.085
Atp6v1a ATPase, H+ transporting, lysosomal V1 subunit A 0.075
Cdcp1 CUB domain containing protein 1 0.071
Arl11 ADP-ribosylation factor-like 11 0.071
Pgam1 phosphoglycerate mutase 1 (brain) 0.070
Ppp2ca protein phosphatase 2, catalytic subunit, alpha isoform 0.067
Cybb cytochrome b-245, beta polypeptide 0.065
Eif4h eukaryotic translation initiation factor 4H 0.065
Fut2 fucosyltransferase 2 (secretor status included) 0.064
Ywhaq tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide 0.063
Tuba1c tubulin, alpha 1C 0.062
Nptn neuroplastin 0.060
Cacna1c calcium channel, voltage-dependent, L type, alpha 1C subunit 0.057
Sirpa signal-regulatory protein alpha 0.054
Arrdc1 arrestin domain containing 1 0.052
Ywhah tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide 0.050
P2ry6 pyrimidinergic receptor P2Y, G-protein coupled, 6 0.050
Lst1 leukocyte specific transcript 1 0.050
Calm2 calmodulin 2 0.049
Morf4l1 mortality factor 4 like 1 0.048
Cd38 CD38 molecule 0.048
C5ar1 complement component 5a receptor 1 0.047
Csf1 colony stimulating factor 1 (macrophage) 0.043
Ptafr platelet-activating factor receptor 0.043
Pfkfb2 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 0.041
Serpinb1a serine (or cysteine) proteinase inhibitor, clade B, member 1a 0.040
Atp6ap1 ATPase, H+ transporting, lysosomal accessory protein 1 0.039
App amyloid beta (A4) precursor protein 0.038
Ppp2cb protein phosphatase 2, catalytic subunit, beta isoform 0.038
Itpr2 inositol 1,4,5-triphosphate receptor, type 2 0.037
Zwint ZW10 interactor 0.034
Rassf5 Ras association (RalGDS/AF-6) domain family member 5 0.032
Acap1 ArfGAP with coiled-coil, ankyrin repeat and PH domains 1 0.031
Tgfbr3 transforming growth factor, beta receptor III 0.030
Cxcr3 chemokine (C-X-C motif) receptor 3 0.029
Csf2rb colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) 0.029
Fkbp1a FK506 binding protein 1a 0.028
Ap2m1 adaptor-related protein complex 2, mu 1 subunit 0.028
Gzmk granzyme K 0.028
Dchs1 dachsous 1 (Drosophila) 0.027
Gcnt3 glucosaminyl (N-acetyl) transferase 3, mucin type 0.026
Il2rg interleukin 2 receptor, gamma 0.026
Hrh2 histamine receptor H 2 0.024
Folr2 folate receptor 2 (fetal) 0.024
Lyn v-yes-1 Yamaguchi sarcoma viral related oncogene homolog 0.024
Hnrnpk heterogeneous nuclear ribonucleoprotein K 0.023
Olr1867 olfactory receptor 1867 0.023
Cd48 Cd48 molecule 0.023
Hpgds hematopoietic prostaglandin D synthase 0.023
Ccr5 chemokine (C-C motif) receptor 5 0.023
Hsbp1 heat shock factor binding protein 1 0.022
Sumo2 SMT3 suppressor of mif two 3 homolog 2 (S. cerevisiae) 0.022
Tmem79 transmembrane protein 79 0.022
Ppp2r1a protein phosphatase 2 (formerly 2A), regulatory subunit A, alpha isoform 0.022
Cltc clathrin, heavy chain (Hc) 0.022
Sdc3 syndecan 3 0.022
Ptger2 prostaglandin E receptor 2 (subtype EP2) 0.022
Cdk5r1 cyclin-dependent kinase 5, regulatory subunit 1 0.022
Plau plasminogen activator, urokinase 0.021
Dock8 dedicator of cytokinesis 8 0.020
Inpp5d inositol polyphosphate-5-phosphatase D 0.020
Itgam integrin, alpha M 0.020
Slc28a3 solute carrier family 28 (sodium-coupled nucleoside transporter), member 3 0.020
RGD1304644 similar to RIKEN cDNA 2310046K01 0.019
Il1b interleukin 1 beta 0.018
RT1-M3-1 RT1 class Ib, locus M3, gene 1 0.018
RGD1310262 hypothetical LOC304650 0.018
Cd247 Cd247 molecule 0.017
Pik3cd phosphoinositide-3-kinase, catalytic, delta polypeptide 0.017
Atp2a3 ATPase, Ca++ transporting, ubiquitous 0.016
Adar adenosine deaminase, RNA-specific 0.016
Tgfbr2 transforming growth factor, beta receptor II 0.015
Ncan neurocan 0.015
Casp1 caspase 1 0.015
Slc14a1 solute carrier family 14 (urea transporter), member 1 0.015
Laptm5 lysosomal protein transmembrane 5 0.015
Dynll1 dynein light chain LC8-type 1 0.015
Psd4 pleckstrin and Sec7 domain containing 4 0.014
Grk4 G protein-coupled receptor kinase 4 0.014
Arhgap25 Rho GTPase activating protein 25 0.014
Chrna7 cholinergic receptor, nicotinic, alpha 7 0.014
Bcl2a1d B-cell leukemia/lymphoma 2 related protein A1d 0.014
Fcgr3a Fc fragment of IgG, low affinity IIIa, receptor 0.014
Cd8a CD8a molecule 0.014
Nkg7 natural killer cell group 7 sequence 0.014
Cyp2s1 cytochrome P450, family 2, subfamily s, polypeptide 1 0.014
Calcrl calcitonin receptor-like 0.014
Mmp12 matrix metallopeptidase 12 0.014
Anxa3 annexin A3 0.014
Slc14a2 solute carrier family 14 (urea transporter), member 2 0.014
Klrb1a killer cell lectin-like receptor subfamily B, member 1A 0.014
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Danio rerio
Name Description Probability Func Analog Organism
coro1a coronin, actin binding protein, 1A 0.043
ptpn6 protein tyrosine phosphatase, non-receptor type 6 0.038
tyr tyrosinase 0.037
phex phosphate regulating gene with homologues to endopeptidases on the X chromosome 0.033
runx3 runt-related transcription factor 3 0.029
zgc:63629 zgc:63629 0.029
trpm7 transient receptor potential cation channel, subfamily M, member 7 0.028
rhogb ras homolog gene family, member Gb 0.028
appl1 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1 0.027
ncf1 neutrophil cytosolic factor 1 0.027
mtmr8 myotubularin related protein 8 0.023
foxi3a forkhead box I3a 0.023
cyt1 type I cytokeratin, enveloping layer 0.022
foxn1 forkhead box N1 0.021
krml2.2 Kreisler (mouse) maf-related leucine zipper homolog 2.2 0.021
tnrc5 trinucleotide repeat containing 5 0.021
smad9 MAD homolog 9 (Drosophila) 0.020
im:7154036 im:7154036 0.020
cxcr3.2 chemokine (C-X-C motif) receptor 3.2 0.019
f2rl1.2 coagulation factor II (thrombin) receptor-like 1.2 0.018
lta4h leukotriene A4 hydrolase 0.018
zgc:172101 zgc:172101 0.018
atxn7l3 ataxin 7-like 3 0.017
lrrc33 leucine rich repeat containing 33 0.016
lgals9l1 lectin, galactoside-binding, soluble, 9 (galectin 9)-like 1 0.016
atp6ap1 ATPase, H+ transporting, lysosomal accessory protein 1 0.016
itm2bb integral membrane protein 2Bb 0.015
LOC100359374 BCL-WAV 0.015
degs2 degenerative spermatocyte homolog 2, lipid desaturase (Drosophila) 0.015
zgc:110010 zgc:110010 0.015
ripk2 receptor-interacting serine-threonine kinase 2 0.015
iqgap1 IQ motif containing GTPase activating protein 1 0.015
zgc:63831 zgc:63831 0.015
rhoab ras homolog gene family, member Ab 0.015
cbfb core-binding factor, beta subunit 0.014
h1m linker histone H1M 0.014
zgc:77304 zgc:77304 0.014
ptprc protein tyrosine phosphatase, receptor type, C 0.014
zgc:66242 zgc:66242 0.014
b4galt1 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1 0.014
celsr1b cadherin EGF LAG seven-pass G-type receptor 1b 0.014
atat1 alpha tubulin acetyltransferase 1 0.014
ptprea protein tyrosine phosphatase, receptor type, E, a 0.014
eml2 echinoderm microtubule associated protein like 2 0.014
tpst1l tyrosylprotein sulfotransferase 1, like 0.013
sec24c SEC24 family, member C (S. cerevisiae) 0.013
zgc:55891 zgc:55891 0.013
tbp TATA box binding protein 0.013
spon2a spondin 2a, extracellular matrix protein 0.012
sla1 Src-like-adaptor 1 0.012
appl2 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2 0.012
acbd3 acyl-Coenzyme A binding domain containing 3 0.012
aspn asporin (LRR class 1) 0.011
ube2i ubiquitin-conjugating enzyme E2I 0.011
galca galactosylceramidase a 0.011
por P450 (cytochrome) oxidoreductase 0.011
taf3 TAF3 RNA polymerase II, TATA box binding protein (TBP)-associated facto 0.011
zgc:114201 zgc:114201 0.011
hnf1bb HNF1 homeobox Bb 0.011
ccl25b chemokine (C-C motif) ligand 25b 0.011
gtf2a1 general transcription factor IIA, 1 0.011
tec tec protein tyrosine kinase 0.011
uevld UEV and lactate/malate dehyrogenase domains 0.011
myhz1.2 myosin, heavy polypeptide 1.2, skeletal muscle 0.011
si:dkey-19f21.3 si:dkey-19f21.3 0.011
styk1 serine/threonine/tyrosine kinase 1 0.011
col17a1b collagen, type XVII, alpha 1b 0.011
arglu1b arginine and glutamate rich 1b 0.011
sec31b Sec31 homolog B (S. cerevisiae) 0.011
ciz1 CDKN1A interacting zinc finger protein 1 0.011
arvcfb armadillo repeat gene deleted in velocardiofacial syndrome b 0.010
rab11al RAB11a, member RAS oncogene family, like 0.010
frzb frizzled-related protein 0.010
zgc:55392 zgc:55392 0.010
ptk6a PTK6 protein tyrosine kinase 6a 0.010
tnfsf10l2 tumor necrosis factor (ligand) superfamily, member 10 like 2 0.010
vps39 vacuolar protein sorting 39 homolog (S. cerevisiae) 0.010
gnb1b guanine nucleotide binding protein (G protein), beta polypeptide 1b 0.010
stat5.2 signal transducer and activator of transcription 5.2 0.010
smad5 MAD homolog 5 (Drosophila) 0.010
ppm1aa protein phosphatase, Mg2+/Mn2+ dependent, 1Aa 0.010
stxbp6l syntaxin binding protein 6 (amisyn), like 0.010
mpp6b membrane protein, palmitoylated 6b (MAGUK p55 subfamily member 6) 0.010
rgs14a regulator of G-protein signaling 14a 0.010
rbpja recombination signal binding protein for immunoglobulin kappa J region a 0.010
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Drosophila melanogaster
Name Description Probability Func Analog Organism
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Homo sapiens
Name Description Probability Func Analog Organism
IL8 interleukin 8 0.593
ERBB2 v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) 0.532
SYK spleen tyrosine kinase 0.515
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) 0.176
CBL Cas-Br-M (murine) ecotropic retroviral transforming sequence 0.166
CCR5 chemokine (C-C motif) receptor 5 0.150
LAT linker for activation of T cells 0.123
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 0.067
SHC1 SHC (Src homology 2 domain containing) transforming protein 1 0.066
CXCL2 chemokine (C-X-C motif) ligand 2 0.066
GRB2 growth factor receptor-bound protein 2 0.065
BLNK B-cell linker 0.063
EGFR epidermal growth factor receptor 0.063
FGR Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog 0.060
CXCL3 chemokine (C-X-C motif) ligand 3 0.058
C19orf50 chromosome 19 open reading frame 50 0.058
UBASH3B ubiquitin associated and SH3 domain containing B 0.055
NCF4 neutrophil cytosolic factor 4, 40kDa 0.045
ERBB3 v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) 0.043
NCF2 neutrophil cytosolic factor 2 0.042
SNAP23 synaptosomal-associated protein, 23kDa 0.040
KDR kinase insert domain receptor (a type III receptor tyrosine kinase) 0.040
FCER1G Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide 0.039
CCL4 chemokine (C-C motif) ligand 4 0.038
PDGFRB platelet-derived growth factor receptor, beta polypeptide 0.038
IL4R interleukin 4 receptor 0.037
CCL2 chemokine (C-C motif) ligand 2 0.036
IL1B interleukin 1, beta 0.036
IL6 interleukin 6 (interferon, beta 2) 0.034
CRKL v-crk sarcoma virus CT10 oncogene homolog (avian)-like 0.030
PPL periplakin 0.028
PDGFRA platelet-derived growth factor receptor, alpha polypeptide 0.026
CCL13 chemokine (C-C motif) ligand 13 0.025
ZNF746 zinc finger protein 746 0.024
CXCL9 chemokine (C-X-C motif) ligand 9 0.022
CCR1 chemokine (C-C motif) receptor 1 0.022
CXCL6 chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2) 0.019
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32) 0.019
PTPRB protein tyrosine phosphatase, receptor type, B 0.019
VEGFA vascular endothelial growth factor A 0.018
SHC2 SHC (Src homology 2 domain containing) transforming protein 2 0.017
CAV1 caveolin 1, caveolae protein, 22kDa 0.017
PGF placental growth factor 0.016
CCL8 chemokine (C-C motif) ligand 8 0.016
CCR7 chemokine (C-C motif) receptor 7 0.015
TFF1 trefoil factor 1 0.015
GAB1 GRB2-associated binding protein 1 0.015
ANKRD27 ankyrin repeat domain 27 (VPS9 domain) 0.015
CCL18 chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated) 0.014
IL10 interleukin 10 0.013
NRP1 neuropilin 1 0.013
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog 0.013
VCAM1 vascular cell adhesion molecule 1 0.013
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 0.013
CCL22 chemokine (C-C motif) ligand 22 0.013
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta 0.013
SLA Src-like-adaptor 0.013
UBR1 ubiquitin protein ligase E3 component n-recognin 1 0.012
CAV2 caveolin 2 0.012
PDGFB platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog) 0.012
HCK hemopoietic cell kinase 0.012
CFH complement factor H 0.012
CCL7 chemokine (C-C motif) ligand 7 0.012
IL7R interleukin 7 receptor 0.011
CXCL5 chemokine (C-X-C motif) ligand 5 0.011
PRKCD protein kinase C, delta 0.011
IL4 interleukin 4 0.010
IL2RG interleukin 2 receptor, gamma 0.010
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Mus musculus
Name Description Probability Func Analog Organism
Ptprc protein tyrosine phosphatase, receptor type, C 0.930
Il4 interleukin 4 0.873
Csf2rb2 colony stimulating factor 2 receptor, beta 2, low-affinity (granulocyte-macrophage) 0.861
Fgr Gardner-Rasheed feline sarcoma viral (Fgr) oncogene homolog 0.858
Ikzf1 IKAROS family zinc finger 1 0.805
Csf3r colony stimulating factor 3 receptor (granulocyte) 0.760
Mefv Mediterranean fever 0.758
Il2rb interleukin 2 receptor, beta chain 0.700
Lyn Yamaguchi sarcoma viral (v-yes-1) oncogene homolog 0.685
Il18rap interleukin 18 receptor accessory protein 0.678
Cd247 CD247 antigen 0.657
Cd40 CD40 antigen 0.644
Tnfrsf9 tumor necrosis factor receptor superfamily, member 9 0.623
Trem3 triggering receptor expressed on myeloid cells 3 0.613
Ccl3 chemokine (C-C motif) ligand 3 0.613
Ifng interferon gamma 0.597
Csf1r colony stimulating factor 1 receptor 0.597
Fcgr1 Fc receptor, IgG, high affinity I 0.582
C5ar1 complement component 5a receptor 1 0.578
Prdm1 PR domain containing 1, with ZNF domain 0.567
Cxcr2 chemokine (C-X-C motif) receptor 2 0.525
Ccr5 chemokine (C-C motif) receptor 5 0.523
Cd7 CD7 antigen 0.521
Inpp5d inositol polyphosphate-5-phosphatase D 0.509
Tnf tumor necrosis factor 0.477
Tyrobp TYRO protein tyrosine kinase binding protein 0.475
Prf1 perforin 1 (pore forming protein) 0.470
Fasl Fas ligand (TNF superfamily, member 6) 0.464
Csf2rb colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) 0.456
Ccl4 chemokine (C-C motif) ligand 4 0.429
Tlr2 toll-like receptor 2 0.424
Ccr1 chemokine (C-C motif) receptor 1 0.398
Niacr1 niacin receptor 1 0.393
Lcn4 lipocalin 4 0.387
Mmp8 matrix metallopeptidase 8 0.377
Il1rn interleukin 1 receptor antagonist 0.374
Itgal integrin alpha L 0.371
Cd19 CD19 antigen 0.366
Met met proto-oncogene 0.362
Cxcr3 chemokine (C-X-C motif) receptor 3 0.359
Tnfrsf4 tumor necrosis factor receptor superfamily, member 4 0.352
Tbxas1 thromboxane A synthase 1, platelet 0.347
Ccl2 chemokine (C-C motif) ligand 2 0.340
Mpo myeloperoxidase 0.336
Cd4 CD4 antigen 0.335
Ncf1 neutrophil cytosolic factor 1 0.333
Il27ra interleukin 27 receptor, alpha 0.333
Fcer1g Fc receptor, IgE, high affinity I, gamma polypeptide 0.319
BC013712 cDNA sequence BC013712 0.319
Dok3 docking protein 3 0.315
Gzmb granzyme B 0.304
Fes feline sarcoma oncogene 0.296
Il10ra interleukin 10 receptor, alpha 0.293
Irg1 immunoresponsive gene 1 0.293
Klrk1 killer cell lectin-like receptor subfamily K, member 1 0.290
Hcst hematopoietic cell signal transducer 0.285
Cma1 chymase 1, mast cell 0.278
Lair1 leukocyte-associated Ig-like receptor 1 0.278
Mitf microphthalmia-associated transcription factor 0.274
Ccl7 chemokine (C-C motif) ligand 7 0.271
Cx3cr1 chemokine (C-X3-C) receptor 1 0.264
Ccr2 chemokine (C-C motif) receptor 2 0.256
S100a8 S100 calcium binding protein A8 (calgranulin A) 0.242
Sh2d2a SH2 domain protein 2A 0.239
Xcr1 chemokine (C motif) receptor 1 0.236
Klrg1 killer cell lectin-like receptor subfamily G, member 1 0.234
Clec4e C-type lectin domain family 4, member e 0.230
Grap2 GRB2-related adaptor protein 2 0.229
P2rx7 purinergic receptor P2X, ligand-gated ion channel, 7 0.221
Nfam1 Nfat activating molecule with ITAM motif 1 0.220
Itgam integrin alpha M 0.217
Sirpa signal-regulatory protein alpha 0.203
Fcrla Fc receptor-like A 0.202
Tnfaip2 tumor necrosis factor, alpha-induced protein 2 0.202
Ncf4 neutrophil cytosolic factor 4 0.201
Fpr1 formyl peptide receptor 1 0.201
Il1f9 interleukin 1 family, member 9 0.200
Sfpi1 SFFV proviral integration 1 0.199
Il4ra interleukin 4 receptor, alpha 0.197
Cd79a CD79A antigen (immunoglobulin-associated alpha) 0.194
Cd44 CD44 antigen 0.194
Ccr3 chemokine (C-C motif) receptor 3 0.188
Csf1 colony stimulating factor 1 (macrophage) 0.184
Slpi secretory leukocyte peptidase inhibitor 0.183
Ctsw cathepsin W 0.182
Selp selectin, platelet 0.179
Tlr7 toll-like receptor 7 0.171
Ifitm6 interferon induced transmembrane protein 6 0.170
Lat linker for activation of T cells 0.166
Foxp3 forkhead box P3 0.164
Cd33 CD33 antigen 0.164
Il1b interleukin 1 beta 0.163
Reg3b regenerating islet-derived 3 beta 0.161
4632428N05Rik RIKEN cDNA 4632428N05 gene 0.157
Bdkrb1 bradykinin receptor, beta 1 0.157
Cd300a CD300A antigen 0.156
Slfn4 schlafen 4 0.155
Lilrb3 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3 0.154
Spn sialophorin 0.151
Apobr apolipoprotein B receptor 0.151
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism