The network for 'negative regulation of transport' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

negative regulation of transport

Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.

Name Description Probability Func Analog Organism
Trhr2 thyrotropin releasing hormone receptor 2 0.298
Kcnq3 potassium voltage-gated channel, KQT-like subfamily, member 3 0.259
Grm5 glutamate receptor, metabotropic 5 0.240
P2ry4 pyrimidinergic receptor P2Y, G-protein coupled, 4 0.234
Hpcal4 hippocalcin-like 4 0.225
Zp1 zona pellucida glycoprotein 1 (sperm receptor) 0.223
Nr4a3 nuclear receptor subfamily 4, group A, member 3 0.211
Il13 interleukin 13 0.211
Ndst1 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1 0.210
Cacng4 calcium channel, voltage-dependent, gamma subunit 4 0.202
S100a10 S100 calcium binding protein A10 0.195
Fgf10 fibroblast growth factor 10 0.189
Prkcg protein kinase C, gamma 0.178
Ptp4a1 protein tyrosine phosphatase type IVA, member 1 0.175
Prl2a1 Prolactin family 2, subfamily a, member 1 0.173
Ncan neurocan 0.171
Slc6a3 solute carrier family 6 (neurotransmitter transporter, dopamine), member 3 0.165
Gng7 guanine nucleotide binding protein (G protein), gamma 7 0.165
Adcy5 adenylate cyclase 5 0.163
Cmklr1 chemokine-like receptor 1 0.156
Anxa5 annexin A5 0.155
Slc18a3 solute carrier family 18 (vesicular acetylcholine), member 3 0.155
Grm7 glutamate receptor, metabotropic 7 0.153
Egr3 early growth response 3 0.149
Cacna1a calcium channel, voltage-dependent, P/Q type, alpha 1A subunit 0.149
Flt1 FMS-related tyrosine kinase 1 0.149
Insrr insulin receptor-related receptor 0.149
Slc6a7 solute carrier family 6 (neurotransmitter transporter, L-proline), member 7 0.147
Ppyr1 pancreatic polypeptide receptor 1 0.146
Syt3 synaptotagmin III 0.144
Adora2a adenosine A2a receptor 0.143
Olr857 olfactory receptor 857 0.142
Iapp islet amyloid polypeptide 0.141
Syn1 synapsin I 0.141
Olr287 olfactory receptor 287 0.137
Cdkn2b cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4) 0.137
Syt6 synaptotagmin VI 0.135
Cacna1c calcium channel, voltage-dependent, L type, alpha 1C subunit 0.134
Olr226 olfactory receptor 226 0.132
Gucy2d guanylate cyclase 2d 0.132
Gip gastric inhibitory polypeptide 0.132
Pcyt1b phosphate cytidylyltransferase 1, choline, beta 0.130
Syt2 synaptotagmin II 0.130
Gabrg1 gamma-aminobutyric acid (GABA) A receptor, gamma 1 0.129
Grin2b glutamate receptor, ionotropic, N-methyl D-aspartate 2B 0.126
Prlh prolactin releasing hormone 0.125
Syn3 synapsin III 0.125
Galr1 galanin receptor 1 0.124
Gpr83 G protein-coupled receptor 83 0.123
Ttc36 tetratricopeptide repeat domain 36 0.123
Itgb1 integrin, beta 1 0.122
Notch3 Notch homolog 3 (Drosophila) 0.121
Rgs9 regulator of G-protein signaling 9 0.121
Myo1d myosin ID 0.120
Akp3 alkaline phosphatase 3, intestine, not Mn requiring 0.119
Syp synaptophysin 0.118
Syt7 synaptotagmin VII 0.118
Lim2 lens intrinsic membrane protein 2 0.118
Prdm2 PR domain containing 2, with ZNF domain 0.117
Chrna2 cholinergic receptor, nicotinic, alpha 2 (neuronal) 0.116
Kcnh7 potassium voltage-gated channel, subfamily H (eag-related), member 7 0.115
Mc5r melanocortin 5 receptor 0.115
Slc28a1 solute carrier family 28 (sodium-coupled nucleoside transporter), member 1 0.114
Syt4 synaptotagmin IV 0.113
Sst somatostatin 0.113
RGD1565168 similar to RAP2A, member of RAS oncogene family 0.113
Kcna6 potassium voltage gated channel, shaker related subfamily, member 6 0.111
Cx3cr1 chemokine (C-X3-C motif) receptor 1 0.109
Guca1b guanylate cyclase activator 1B 0.108
Impg2 interphotoreceptor matrix proteoglycan 2 0.108
Kcnj10 potassium inwardly-rectifying channel, subfamily J, member 10 0.108
Fgf7 fibroblast growth factor 7 0.106
Ucp1 uncoupling protein 1 (mitochondrial, proton carrier) 0.106
Slc26a2 solute carrier family 26 (sulfate transporter), member 2 0.105
Slc8a2 solute carrier family 8 (sodium/calcium exchanger), member 2 0.105
Nckap1 NCK-associated protein 1 0.104
Rap1b RAP1B, member of RAS oncogene family 0.104
Unc5a unc-5 homolog A (C. elegans) 0.102
Syt8 synaptotagmin VIII 0.100
Chrng cholinergic receptor, nicotinic, gamma 0.100
Atp4b ATPase, H+/K+ exchanging, beta polypeptide 0.100
Kcnk9 potassium channel, subfamily K, member 9 0.099
Acrv1 acrosomal vesicle protein 1 0.099
Cyp11a1 cytochrome P450, family 11, subfamily a, polypeptide 1 0.098
Pja2 praja 2, RING-H2 motif containing 0.098
Nptn neuroplastin 0.097
Cdh22 cadherin 22 0.097
Cyp2a3 cytochrome P450, family 2, subfamily a, polypeptide 3 0.096
Ube2g1 ubiquitin-conjugating enzyme E2G 1 (UBC7 homolog, yeast) 0.095
Ptafr platelet-activating factor receptor 0.094
Ren renin 0.094
B3gat1 beta-1,3-glucuronyltransferase 1 (glucuronosyltransferase P) 0.094
Tgfbr3 transforming growth factor, beta receptor III 0.093
Ntrk1 neurotrophic tyrosine kinase, receptor, type 1 0.093
Snrk SNF related kinase 0.093
Grin2d glutamate receptor, ionotropic, N-methyl D-aspartate 2D 0.093
Cebpb CCAAT/enhancer binding protein (C/EBP), beta 0.092
Strn striatin, calmodulin binding protein 0.092
Pip prolactin induced protein 0.091
Slc6a11 solute carrier family 6 (neurotransmitter transporter, GABA), member 11 0.091
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
glp-1 Protein GLP-1 0.013
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Danio rerio
Name Description Probability Func Analog Organism
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Drosophila melanogaster
Name Description Probability Func Analog Organism
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Homo sapiens
Name Description Probability Func Analog Organism
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide 1.000
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) 0.996
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide 0.977
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide 0.968
SNX9 sorting nexin 9 0.968
APP amyloid beta (A4) precursor protein 0.951
PTPN1 protein tyrosine phosphatase, non-receptor type 1 0.944
MAP3K3 mitogen-activated protein kinase kinase kinase 3 0.935
PTPN6 protein tyrosine phosphatase, non-receptor type 6 0.929
GRB10 growth factor receptor-bound protein 10 0.910
GSTM1 glutathione S-transferase mu 1 0.903
FLNA filamin A, alpha 0.898
GSK3B glycogen synthase kinase 3 beta 0.898
NCF1 neutrophil cytosolic factor 1 0.897
ANXA1 annexin A1 0.888
CAV1 caveolin 1, caveolae protein, 22kDa 0.880
SLC9A3R1 solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1 0.836
FN1 fibronectin 1 0.833
MED15 mediator complex subunit 15 0.827
CAMK2A calcium/calmodulin-dependent protein kinase II alpha 0.826
PRKCA protein kinase C, alpha 0.823
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) 0.811
THBS1 thrombospondin 1 0.804
CSK c-src tyrosine kinase 0.801
RELA v-rel reticuloendotheliosis viral oncogene homolog A (avian) 0.800
INSR insulin receptor 0.782
PTEN phosphatase and tensin homolog 0.749
HIPK3 homeodomain interacting protein kinase 3 0.742
MYD88 myeloid differentiation primary response gene (88) 0.736
C1QA complement component 1, q subcomponent, A chain 0.731
LILRA6 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 6 0.728
CAB39 calcium binding protein 39 0.719
NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like 0.715
GSTM2 glutathione S-transferase mu 2 (muscle) 0.709
RNF11 ring finger protein 11 0.707
APOA1 apolipoprotein A-I 0.705
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 0.703
FASLG Fas ligand (TNF superfamily, member 6) 0.697
ADAM15 ADAM metallopeptidase domain 15 0.688
ACVR1B activin A receptor, type IB 0.679
ITCH itchy E3 ubiquitin protein ligase homolog (mouse) 0.677
MPDZ multiple PDZ domain protein 0.675
PXN paxillin 0.673
ERBB3 v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) 0.669
ZYX zyxin 0.666
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1 0.662
ANXA7 annexin A7 0.656
PML promyelocytic leukemia 0.630
TLN1 talin 1 0.628
A2M alpha-2-macroglobulin 0.627
MAPK3 mitogen-activated protein kinase 3 0.625
IRS1 insulin receptor substrate 1 0.616
ACTN4 actinin, alpha 4 0.608
LILRB1 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1 0.606
JAG1 jagged 1 0.592
HIPK2 homeodomain interacting protein kinase 2 0.585
MAP3K1 mitogen-activated protein kinase kinase kinase 1 0.574
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 0.572
GNAI2 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 0.571
POU5F1 POU class 5 homeobox 1 0.569
FYN FYN oncogene related to SRC, FGR, YES 0.564
PAG1 phosphoprotein associated with glycosphingolipid microdomains 1 0.561
FBXW11 F-box and WD repeat domain containing 11 0.561
GRIN2B glutamate receptor, ionotropic, N-methyl D-aspartate 2B 0.559
VIM vimentin 0.556
BTRC beta-transducin repeat containing 0.545
CKAP5 cytoskeleton associated protein 5 0.544
CRYAB crystallin, alpha B 0.544
SFN stratifin 0.539
CREBBP CREB binding protein 0.532
SMPD1 sphingomyelin phosphodiesterase 1, acid lysosomal 0.524
HDAC1 histone deacetylase 1 0.504
DTX3L deltex 3-like (Drosophila) 0.501
TOP1 topoisomerase (DNA) I 0.497
HSPB1 heat shock 27kDa protein 1 0.494
EGFR epidermal growth factor receptor 0.485
RAF1 v-raf-1 murine leukemia viral oncogene homolog 1 0.482
MAP3K5 mitogen-activated protein kinase kinase kinase 5 0.474
DCAF7 DDB1 and CUL4 associated factor 7 0.469
FAF1 Fas (TNFRSF6) associated factor 1 0.465
HSPB2 heat shock 27kDa protein 2 0.457
ITGB4 integrin, beta 4 0.455
TGIF1 TGFB-induced factor homeobox 1 0.452
CASP8 caspase 8, apoptosis-related cysteine peptidase 0.450
RAPGEF2 Rap guanine nucleotide exchange factor (GEF) 2 0.441
ILK integrin-linked kinase 0.434
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 0.432
SREBF2 sterol regulatory element binding transcription factor 2 0.431
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 0.429
KCNE1 potassium voltage-gated channel, Isk-related family, member 1 0.427
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 0.423
ERBB2IP erbb2 interacting protein 0.409
FAS Fas (TNF receptor superfamily, member 6) 0.405
AKT1 v-akt murine thymoma viral oncogene homolog 1 0.402
NEDD4 neural precursor cell expressed, developmentally down-regulated 4 0.401
FOXD3 forkhead box D3 0.401
YAP1 Yes-associated protein 1 0.398
LATS2 LATS, large tumor suppressor, homolog 2 (Drosophila) 0.397
CRHR1 corticotropin releasing hormone receptor 1 0.397
IL1R1 interleukin 1 receptor, type I 0.396
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Mus musculus
Name Description Probability Func Analog Organism
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism
BMH2 Bmh2p 0.015
SAC6 Sac6p 0.012
SET1 Set1p 0.012