The network for 'regulation of cellular response to stress' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

regulation of cellular response to stress

Any process that modulates the frequency, rate or extent of a cellular response to stress. Cellular response to stress is a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation).

Rattus norvegicus
Name Description Probability Func Analog Organism
Gria2 glutamate receptor, ionotropic, AMPA 2 0.278
Mapk1 mitogen activated protein kinase 1 0.203
Atp1a1 ATPase, Na+/K+ transporting, alpha 1 polypeptide 0.203
Vegfa vascular endothelial growth factor A 0.163
Ppp3r1 protein phosphatase 3, regulatory subunit B, alpha isoform 0.133
Mapk8ip1 mitogen-activated protein kinase 8 interacting protein 1 0.123
Tnfrsf1a tumor necrosis factor receptor superfamily, member 1a 0.115
March5 membrane-associated ring finger (C3HC4) 5 0.111
Taf10 TAF10 RNA polymerase II, TATA box binding protein (TBP)-associated factor 0.092
Gna12 guanine nucleotide binding protein (G protein) alpha 12 0.089
Socs3 suppressor of cytokine signaling 3 0.087
Vcan versican 0.087
Ctdsp1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1 0.085
Ndst1 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1 0.083
Mapk6 mitogen-activated protein kinase 6 0.079
Hoxc4 homeo box C4 0.078
Prkcg protein kinase C, gamma 0.078
S1pr2 sphingosine-1-phosphate receptor 2 0.072
Il1a interleukin 1 alpha 0.071
Mpp2 membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2) 0.069
Dapk3 death-associated protein kinase 3 0.068
Txnrd1 thioredoxin reductase 1 0.067
Grm7 glutamate receptor, metabotropic 7 0.067
Prkar2a protein kinase, cAMP dependent regulatory, type II alpha 0.065
Pcdhb12 protocadherin beta 12 0.065
Hist1h1a histone cluster 1, H1a 0.064
Prkg2 protein kinase, cGMP-dependent, type II 0.064
Onecut1 one cut homeobox 1 0.062
Pstpip1 proline-serine-threonine phosphatase-interacting protein 1 0.059
Arih1 ariadne ubiquitin-conjugating enzyme E2 binding protein homolog 1 (Drosophila) 0.058
Pick1 protein interacting with PRKCA 1 0.057
Kpnb1 karyopherin (importin) beta 1 0.056
Mapk14 mitogen activated protein kinase 14 0.056
Cand1 cullin-associated and neddylation-dissociated 1 0.056
Map3k1 mitogen activated protein kinase kinase kinase 1 0.055
Sqstm1 sequestosome 1 0.054
Pebp1 phosphatidylethanolamine binding protein 1 0.054
Cdc37 cell division cycle 37 homolog (S. cerevisiae) 0.052
Musk muscle, skeletal, receptor tyrosine kinase 0.052
Tgfb2 transforming growth factor, beta 2 0.051
Sbk1 SH3-binding domain kinase 1 0.051
Arnt aryl hydrocarbon receptor nuclear translocator 0.051
Litaf lipopolysaccharide-induced TNF factor 0.050
Kcnk1 potassium channel, subfamily K, member 1 0.049
Eif5 eukaryotic translation initiation factor 5 0.049
Lims1 LIM and senescent cell antigen-like domains 1 0.049
Usf2 upstream transcription factor 2, c-fos interacting 0.049
Ube2g1 ubiquitin-conjugating enzyme E2G 1 (UBC7 homolog, yeast) 0.049
Tor1aip1 torsin A interacting protein 1 0.048
Pgr progesterone receptor 0.047
Nudt3 nudix (nucleoside diphosphate linked moiety X)-type motif 3 0.047
Grip1 glutamate receptor interacting protein 1 0.046
Prkcd protein kinase C, delta 0.045
RGD1305793 similar to hypothetical protein FLJ20154 0.045
Smek2 SMEK homolog 2, suppressor of mek1 (Dictyostelium) 0.045
Mcf2l MCF.2 cell line derived transforming sequence-like 0.044
Zfp706 zinc finger protein 706 0.043
Il1r1 interleukin 1 receptor, type I 0.043
Gpi glucose phosphate isomerase 0.042
Nppc natriuretic peptide precursor C 0.041
Trip12 thyroid hormone receptor interactor 12 0.041
Eif4h eukaryotic translation initiation factor 4H 0.041
Cry2 cryptochrome 2 (photolyase-like) 0.040
Lox lysyl oxidase 0.040
Gucy1a3 guanylate cyclase 1, soluble, alpha 3 0.040
Dctn4 dynactin 4 0.040
Mapk8 mitogen-activated protein kinase 8 0.040
Syngr2 synaptogyrin 2 0.039
Sdcbp syndecan binding protein 0.039
Qars glutaminyl-tRNA synthetase 0.039
Txnl1 thioredoxin-like 1 0.038
Slc6a15 solute carrier family 6 (neutral amino acid transporter), member 15 0.038
Map2 microtubule-associated protein 2 0.038
Wdr26 WD repeat domain 26 0.038
Cltc clathrin, heavy chain (Hc) 0.037
Stard10 StAR-related lipid transfer (START) domain containing 10 0.037
Nek9 NIMA (never in mitosis gene a)- related kinase 9 0.037
Il6 interleukin 6 0.037
Calm3 calmodulin 3 0.037
Hes3 hairy and enhancer of split 3 (Drosophila) 0.036
Adora2a adenosine A2a receptor 0.036
Olr1496 olfactory receptor 1496 0.036
Pip4k2b phosphatidylinositol-5-phosphate 4-kinase, type II, beta 0.036
Pctk2 PCTAIRE protein kinase 2 0.036
RT1-Da RT1 class II, locus Da 0.036
Gria1 glutamate receptor, ionotropic, AMPA 1 0.035
Cyth1 cytohesin 1 0.035
Plaa phospholipase A2, activating protein 0.035
Rala v-ral simian leukemia viral oncogene homolog A (ras related) 0.035
RT1-Ba RT1 class II, locus Ba 0.034
Mapk9 mitogen-activated protein kinase 9 0.034
Ezr ezrin 0.034
Grin2d glutamate receptor, ionotropic, N-methyl D-aspartate 2D 0.034
Myd88 myeloid differentiation primary response gene 88 0.034
Serinc1 serine incorporator 1 0.034
Errfi1 ERBB receptor feedback inhibitor 1 0.034
Jtb jumping translocation breakpoint 0.034
Gnai2 guanine nucleotide binding protein (G protein), alpha inhibiting 2 0.034
Gtf2i general transcription factor II I 0.034
Rab15 RAB15, member RAS oncogene family 0.034
Loading network...
Caenorhabditis elegans
Name Description Probability Func Analog Organism
egl-18 Protein EGL-18 0.077
tps-1 Protein TPS-1 0.048
cst-1 Protein CST-1 0.041
mig-15 Protein MIG-15 0.036
nhr-6 Protein NHR-6 0.035
nipi-3 Protein NIPI-3 0.032
nphp-4 Protein NPHP-4 0.031
skr-1 Protein SKR-1 0.028
csn-5 Protein CSN-5 0.028
lin-12 Protein LIN-12 0.027
C36E6.1 Protein C36E6.1 0.026
Y82E9BR.13 Protein Y82E9BR.13 0.025
ser-3 Protein SER-3 0.024
CELE_C01G6.5 Protein C01G6.5 0.024
zyg-9 Protein ZYG-9 0.023
spd-5 Protein SPD-5 0.022
zyg-8 Protein ZYG-8 0.022
par-5 Protein PAR-5 0.022
itr-1 Protein ITR-1 0.022
R05D3.8 Protein R05D3.8 0.021
glp-1 Protein GLP-1 0.021
miz-1 Protein MIZ-1 0.020
F59E12.11 Protein F59E12.11 0.020
lat-1 Protein LAT-1 0.020
eaf-1 Protein EAF-1 0.020
pph-4.1 Protein PPH-4.1 0.018
prx-14 Protein PRX-14 0.018
lin-25 Protein LIN-25 0.018
nhr-49 Protein NHR-49 0.018
gst-7 Protein GST-7 0.017
sel-10 Protein SEL-10 0.017
xbp-1 Protein XBP-1 0.017
ddb-1 Protein DDB-1 0.017
mrt-2 Protein MRT-2 0.017
csnk-1 Protein CSNK-1 0.017
let-60 Protein LET-60 0.017
Y51F10.7 Protein Y51F10.7 0.017
sem-5 Protein SEM-5 0.017
sym-4 Protein SYM-4 0.016
asah-1 Protein ASAH-1 0.016
eif-3.I Protein EIF-3.I 0.016
tol-1 Protein TOL-1 0.016
egl-46 Protein EGL-46 0.016
sna-1 Protein SNA-1 0.016
ldb-1 Protein LDB-1 0.016
dlk-1 Protein DLK-1 0.015
chd-7 Protein CHD-7 0.015
lin-45 Protein LIN-45 0.015
frm-7 Protein FRM-7 0.015
drp-1 Protein DRP-1 0.015
hsf-1 Protein HSF-1 0.015
C14B1.3 Protein C14B1.3 0.015
haly-1 Protein HALY-1 0.015
ZC449.5 Protein ZC449.5 0.015
atg-18 Protein ATG-18 0.015
mac-1 Protein MAC-1 0.015
pbs-7 Protein PBS-7 0.015
mpz-2 Protein MPZ-2 0.015
unc-16 Protein UNC-16 0.014
ulp-2 Protein ULP-2 0.014
sac-1 Protein SAC-1 0.014
rpt-3 Protein RPT-3 0.014
F31D4.2 Protein F31D4.2 0.014
dpy-22 Protein DPY-22 0.014
sma-1 Protein SMA-1 0.014
daf-2 Protein DAF-2 0.014
atg-3 Protein ATG-3 0.014
rcn-1 Protein RCN-1 0.013
epi-1 Protein EPI-1 0.013
zak-1 Protein ZAK-1 0.013
let-70 Protein LET-70 0.013
itsn-1 Protein ITSN-1 0.013
F36D4.5 Protein F36D4.5 0.013
daf-3 Protein DAF-3 0.013
dhs-12 Protein DHS-12 0.013
ten-1 Protein TEN-1 0.013
H05C05.2 Protein H05C05.2 0.013
rgs-7 Protein RGS-7 0.012
aak-2 Protein AAK-2 0.012
ncam-1 Protein NCAM-1 0.012
F52C12.4 Protein F52C12.4 0.012
F18A1.6 Protein F18A1.6 0.012
pph-6 Protein PPH-6 0.012
pqn-44 Protein PQN-44 0.012
cpt-1 Protein CPT-1 0.012
che-13 Protein CHE-13 0.012
nfyb-1 Protein NFYB-1 0.012
R10E4.1 Protein R10E4.1 0.012
daf-19 Protein DAF-19 0.012
ant-1.1 Protein ANT-1.1 0.012
ash-2 Protein ASH-2 0.012
uri-1 Protein URI-1 0.012
skn-1 Protein SKN-1 0.012
CELE_ZK1073.1 Protein ZK1073.1 0.012
gmeb-1 Protein GMEB-1 0.011
dnj-12 Protein DNJ-12 0.011
CELE_F20D1.3 Protein F20D1.3 0.011
zer-1 Protein ZER-1 0.011
crt-1 Protein CRT-1 0.011
F21A10.2 Protein F21A10.2 0.011
Loading network...
Danio rerio
Name Description Probability Func Analog Organism
notch3 notch homolog 3 0.078
chd chordin 0.077
flh floating head 0.075
foxa3 forkhead box A3 0.074
dkk1b dickkopf 1b 0.068
cdh1 cadherin 1, epithelial 0.052
bcl2l1 bcl2-like 1 0.046
fn1 fibronectin 1 0.041
ctsl1a cathepsin L, 1 a 0.039
ppm1aa protein phosphatase, Mg2+/Mn2+ dependent, 1Aa 0.038
fzd7a frizzled homolog 7a 0.038
il6r interleukin 6 receptor 0.037
stc1l stanniocalcin 1, like 0.036
epha4a eph receptor A4a 0.036
odc1 ornithine decarboxylase 1 0.034
baxa bcl2-associated X protein, a 0.033
cry3 cryptochrome 3 0.030
ywhae1 tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide 1 0.029
cebpb CCAAT/enhancer binding protein (C/EBP), beta 0.028
gsc goosecoid 0.028
pias4a protein inhibitor of activated STAT, 4a 0.027
arf2 ADP-ribosylation factor 2 0.027
mapk3 mitogen-activated protein kinase 3 0.026
sox19a SRY-box containing gene 19a 0.026
prpf4b PRP4 pre-mRNA processing factor 4 homolog B 0.026
notch2 notch homolog 2 0.025
per3 period homolog 3 (Drosophila) 0.024
igf1ra insulin-like growth factor 1a receptor 0.024
pafah1b1a platelet-activating factor acetylhydrolase, isoform Ib, alpha subunit a 0.024
tlr3 toll-like receptor 3 0.024
st8sia2 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2 0.023
ripk2 receptor-interacting serine-threonine kinase 2 0.023
nr3c1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 0.023
arl4ab ADP-ribosylation factor-like 4ab 0.023
nod1 nucleotide-binding oligomerization domain containing 1 0.023
ncor1 nuclear receptor co-repressor 1 0.022
tbx6 T-box gene 6 0.022
gfer growth factor, augmenter of liver regeneration (ERV1 homolog, S. cerevisiae) 0.022
ephb4a eph receptor B4a 0.022
bmp2b bone morphogenetic protein 2b 0.022
smad5 MAD homolog 5 (Drosophila) 0.021
cmyb transcription factor cmyb 0.021
atf3 activating transcription factor 3 0.021
mcl1a myeloid cell leukemia sequence 1a 0.021
ptena phosphatase and tensin homolog A 0.021
trim13 tripartite motif-containing 13 0.021
fgf3 fibroblast growth factor 3 0.021
zbtb4 zinc finger and BTB domain containing 4 0.021
igf1 insulin-like growth factor 1 0.021
osr1 odd-skipped related 1 (Drosophila) 0.020
dvl2 dishevelled, dsh homolog 2 (Drosophila) 0.020
hspa4a heat shock protein 4a 0.020
znf703 zinc finger protein 703 0.020
jag2 jagged 2 0.020
pafah1b1b platelet-activating factor acetylhydrolase, isoform Ib, alpha subunit b 0.019
esco2 establishment of cohesion 1 homolog 2 0.019
nrg2a neuregulin 2a 0.019
dhfr dihydrofolate reductase 0.019
wnt5a wingless-type MMTV integration site family, member 5a 0.019
elavl1 ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R) 0.019
bbc3 BCL2 binding component 3 0.019
eng1a engrailed 1a 0.019
hbbe3 hemoglobin beta embryonic-3 0.019
cxcl12a chemokine (C-X-C motif) ligand 12a (stromal cell-derived factor 1) 0.019
sf3b1 splicing factor 3b, subunit 1 0.018
ctbp2l C-terminal binding protein 2, like 0.018
furinb furin (paired basic amino acid cleaving enzyme) b 0.018
dbx1a developing brain homeobox 1a 0.018
hmga1a high mobility group AT-hook 1a 0.017
furina furin (paired basic amino acid cleaving enzyme) a 0.017
tm9sf2 transmembrane 9 superfamily member 2 0.017
tp53bp2 tumor protein p53 binding protein, 2 0.017
ctsl1b cathepsin L, 1 b 0.017
sod1 superoxide dismutase 1, soluble 0.017
ifnphi1 interferon phi 1 0.017
igf1rb insulin-like growth factor 1b receptor 0.016
ved ventrally expressed dharma/bozozok antagonist 0.016
ran ras-related nuclear protein 0.016
frzb frizzled-related protein 0.016
spry2 sprouty homolog 2 0.016
crip2 cysteine-rich protein 2 0.015
nkx6.2 NK6 transcription factor related, locus 2 0.015
eif4e eukaryotic translation initiation factor 4e 0.015
gro1 groucho 1 0.015
ntn2 netrin 2 0.015
cand1 cullin-associated and neddylation-dissociated 1 0.015
mapk14a mitogen-activated protein kinase 14a 0.015
gstp1 glutathione S-transferase pi 0.015
rbb4 retinoblastoma binding protein 4 0.015
her1 hairy-related 1 0.015
card9 caspase recruitment domain family, member 9 0.015
mmp9 matrix metalloproteinase 9 0.015
rpsa ribosomal protein SA 0.015
seh1l SEH1-like (S. cerevisiae) 0.014
cyp26c1 cytochrome P450, family 26, subfamily C, polypeptide 1 0.014
mycn v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian) 0.014
ccng1 cyclin G1 0.014
dab1a disabled homolog 1a (Drosophila) 0.014
gro2 groucho 2 0.014
tipin timeless interacting protein 0.014
Loading network...
Drosophila melanogaster
Name Description Probability Func Analog Organism
bsk basket 0.805
Sir2 CG5216 gene product from transcript CG5216-RA 0.744
Mpk2 CG5475 gene product from transcript CG5475-RB 0.677
p53 CG33336 gene product from transcript CG33336-RB 0.666
baz bazooka 0.660
skpA CG16983 gene product from transcript CG16983-RD 0.652
drk downstream of receptor kinase 0.640
shg shotgun 0.620
Thor CG8846 gene product from transcript CG8846-RA 0.587
p38b CG7393 gene product from transcript CG7393-RA 0.570
Rab7 Rab-protein 7 0.560
dco discs overgrown 0.539
Rel Relish 0.516
pan pangolin 0.494
Pi3K92E CG4141 gene product from transcript CG4141-RB 0.480
Akt1 CG4006 gene product from transcript CG4006-RA 0.461
Grip84 gamma-tubulin ring protein 84 0.420
HLHmgamma E(spl) region transcript mgamma 0.391
Caf1 Chromatin assembly factor 1 subunit 0.390
babo baboon 0.379
mus205 mutagen-sensitive 205 0.372
Pink1 PTEN-induced putative kinase 1 0.355
Rho1 CG8416 gene product from transcript CG8416-RB 0.340
yki yorkie 0.315
Sos Son of sevenless 0.314
ctp cut up 0.291
Dcr-1 Dicer-1 0.281
Ptp69D Protein tyrosine phosphatase 69D 0.280
CaMKII Calcium/calmodulin-dependent protein kinase II 0.270
lqf liquid facets 0.266
Stat92E Signal-transducer and activator of transcription protein at 92E 0.262
Su(H) Suppressor of Hairless 0.258
M6 CG7540 gene product from transcript CG7540-RA 0.247
Jra Jun-related antigen 0.243
Pkn Protein kinase related to protein kinase N 0.236
lok loki 0.232
ago archipelago 0.230
Dsp1 Dorsal switch protein 1 0.228
foxo forkhead box, sub-group O 0.224
Lap1 CG10255 gene product from transcript CG10255-RA 0.223
ed echinoid 0.220
CG10743 CG10743 gene product from transcript CG10743-RB 0.218
Spn Spinophilin 0.217
bel belle 0.215
CG1347 CG1347 gene product from transcript CG1347-RB 0.214
sno strawberry notch 0.213
18w 18 wheeler 0.212
Atg13 Autophagy-specific gene 13 0.212
CG5794 CG5794 gene product from transcript CG5794-RB 0.207
HLHmdelta E(spl) region transcript mdelta 0.204
rut rutabaga 0.193
mask multiple ankyrin repeats single KH domain 0.191
Atg1 Autophagy-specific gene 1 0.188
POSH Plenty of SH3s 0.185
spin spinster 0.180
Hsp26 Heat shock protein 26 0.178
debcl death executioner Bcl-2 homologue 0.174
ik2 IkappaB kinase-like 2 0.172
X11L CG5675 gene product from transcript CG5675-RB 0.171
imd immune deficiency 0.169
eIF-4E Eukaryotic initiation factor 4E 0.167
Crc Calreticulin 0.167
Sema-1a CG18405 gene product from transcript CG18405-RD 0.167
mib1 mind bomb 1 0.164
aop anterior open 0.163
cbt cabut 0.161
HLHm7 E(spl) region transcript m7 0.158
CG31198 CG31198 gene product from transcript CG31198-RA 0.156
S6kII RPS6-protein kinase-II 0.156
CG9894 CG9894 gene product from transcript CG9894-RB 0.153
Stim Stromal interaction molecule 0.152
E(spl) Enhancer of split 0.152
Smc5 CG32438 gene product from transcript CG32438-RE 0.151
fng fringe 0.146
Dab Disabled 0.144
polo CG12306 gene product from transcript CG12306-RA 0.143
gek genghis khan 0.142
Hsc70-4 Heat shock protein cognate 4 0.141
nmo nemo 0.140
shn schnurri 0.140
Sp7 Serine protease 7 0.136
sd scalloped 0.136
Dcp-1 Death caspase-1 0.131
sev sevenless 0.131
LanA Laminin A 0.127
Smox Smad on X 0.127
CG31343 CG31343 gene product from transcript CG31343-RA 0.126
Dad Daughters against dpp 0.126
Liprin-alpha CG11199 gene product from transcript CG11199-RB 0.125
fz2 frizzled 2 0.125
EndoGI Endonuclease G inhibitor 0.125
Mekk1 CG7717 gene product from transcript CG7717-RB 0.123
Abl Abl tyrosine kinase 0.122
bib big brain 0.122
LIMK1 LIM-kinase1 0.120
Rheb CG1081 gene product from transcript CG1081-RA 0.118
arm armadillo 0.118
Atpalpha Na pump alpha subunit 0.118
HLHm5 E(spl) region transcript m5 0.118
scny scrawny 0.118
Loading network...
Homo sapiens
Name Description Probability Func Analog Organism
TP53 tumor protein p53 1.000
BIRC3 baculoviral IAP repeat containing 3 0.997
BRCA1 breast cancer 1, early onset 0.996
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide 0.988
CASP8 caspase 8, apoptosis-related cysteine peptidase 0.987
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) 0.986
ERBB2 v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) 0.984
CBL Cas-Br-M (murine) ecotropic retroviral transforming sequence 0.983
EGFR epidermal growth factor receptor 0.978
MAPK14 mitogen-activated protein kinase 14 0.977
SQSTM1 sequestosome 1 0.965
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 0.964
PTK2 PTK2 protein tyrosine kinase 2 0.962
CAV1 caveolin 1, caveolae protein, 22kDa 0.958
RIPK2 receptor-interacting serine-threonine kinase 2 0.955
UBE2I ubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast) 0.943
CRK v-crk sarcoma virus CT10 oncogene homolog (avian) 0.936
PDGFRB platelet-derived growth factor receptor, beta polypeptide 0.927
MRE11A MRE11 meiotic recombination 11 homolog A (S. cerevisiae) 0.922
DAXX death-domain associated protein 0.918
SMAD3 SMAD family member 3 0.910
H2AFX H2A histone family, member X 0.905
TRAF6 TNF receptor-associated factor 6 0.905
CDC42 cell division cycle 42 (GTP binding protein, 25kDa) 0.904
UBC ubiquitin C 0.899
BCL2 B-cell CLL/lymphoma 2 0.897
MAP3K11 mitogen-activated protein kinase kinase kinase 11 0.878
SRC v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) 0.864
MAPK8 mitogen-activated protein kinase 8 0.862
CREBBP CREB binding protein 0.860
RAF1 v-raf-1 murine leukemia viral oncogene homolog 1 0.854
EP300 E1A binding protein p300 0.847
SFN stratifin 0.845
SIRT1 sirtuin 1 0.845
TRAF1 TNF receptor-associated factor 1 0.841
HUWE1 HECT, UBA and WWE domain containing 1 0.839
CFLAR CASP8 and FADD-like apoptosis regulator 0.837
BIRC2 baculoviral IAP repeat containing 2 0.830
CUL1 cullin 1 0.823
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6 0.820
MAP1LC3B microtubule-associated protein 1 light chain 3 beta 0.818
FAS Fas (TNF receptor superfamily, member 6) 0.817
SFPQ splicing factor proline/glutamine-rich 0.813
XIAP X-linked inhibitor of apoptosis 0.804
CDK4 cyclin-dependent kinase 4 0.798
BCAR1 breast cancer anti-estrogen resistance 1 0.787
MAPK1 mitogen-activated protein kinase 1 0.786
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1 0.784
SOCS1 suppressor of cytokine signaling 1 0.782
RELA v-rel reticuloendotheliosis viral oncogene homolog A (avian) 0.772
MAP3K5 mitogen-activated protein kinase kinase kinase 5 0.764
UBE2V1 ubiquitin-conjugating enzyme E2 variant 1 0.762
SKIL SKI-like oncogene 0.751
NCOA3 nuclear receptor coactivator 3 0.745
FGFR2 fibroblast growth factor receptor 2 0.745
SIN3A SIN3 homolog A, transcription regulator (yeast) 0.742
CSNK1E casein kinase 1, epsilon 0.739
PPP2CA protein phosphatase 2, catalytic subunit, alpha isozyme 0.725
FANCD2 Fanconi anemia, complementation group D2 0.711
THOC4 THO complex 4 0.707
JAK2 Janus kinase 2 0.695
BCL2L11 BCL2-like 11 (apoptosis facilitator) 0.695
RCC1 regulator of chromosome condensation 1 0.691
CSNK2A1 casein kinase 2, alpha 1 polypeptide 0.684
FYN FYN oncogene related to SRC, FGR, YES 0.668
AKT1 v-akt murine thymoma viral oncogene homolog 1 0.662
MYD88 myeloid differentiation primary response gene (88) 0.648
BCL2L1 BCL2-like 1 0.647
GSK3B glycogen synthase kinase 3 beta 0.647
MAP2K1 mitogen-activated protein kinase kinase 1 0.644
CASP1 caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase) 0.637
HDAC1 histone deacetylase 1 0.631
LAT linker for activation of T cells 0.621
PPP2R1A protein phosphatase 2, regulatory subunit A, alpha 0.613
JUN jun proto-oncogene 0.612
CHEK1 CHK1 checkpoint homolog (S. pombe) 0.609
LRRK2 leucine-rich repeat kinase 2 0.593
UHRF2 ubiquitin-like with PHD and ring finger domains 2 0.584
MDM2 Mdm2 p53 binding protein homolog (mouse) 0.580
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) 0.574
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 0.568
FGFR1 fibroblast growth factor receptor 1 0.566
BMPR1A bone morphogenetic protein receptor, type IA 0.564
MCL1 myeloid cell leukemia sequence 1 (BCL2-related) 0.557
TRAF2 TNF receptor-associated factor 2 0.547
GABARAPL2 GABA(A) receptor-associated protein-like 2 0.534
MAGEA2 melanoma antigen family A, 2 0.533
BID BH3 interacting domain death agonist 0.528
GABARAP GABA(A) receptor-associated protein 0.526
PTBP1 polypyrimidine tract binding protein 1 0.522
EEF1G eukaryotic translation elongation factor 1 gamma 0.516
ZNF43 zinc finger protein 43 0.508
MAP3K1 mitogen-activated protein kinase kinase kinase 1 0.505
TRAF5 TNF receptor-associated factor 5 0.504
DDIT3 DNA-damage-inducible transcript 3 0.503
PTPN1 protein tyrosine phosphatase, non-receptor type 1 0.503
ZMYM2 zinc finger, MYM-type 2 0.499
TXN thioredoxin 0.496
CDK2 cyclin-dependent kinase 2 0.493
MAP2K4 mitogen-activated protein kinase kinase 4 0.493
Loading network...
Mus musculus
Name Description Probability Func Analog Organism
Pten phosphatase and tensin homolog 1.000
Trp53 transformation related protein 53 1.000
Traf6 TNF receptor-associated factor 6 0.999
Mapk8 mitogen-activated protein kinase 8 0.993
Mapk14 mitogen-activated protein kinase 14 0.983
Cd40 CD40 antigen 0.973
Clock circadian locomotor output cycles kaput 0.952
Cdk4 cyclin-dependent kinase 4 0.951
Pik3ca phosphatidylinositol 3-kinase, catalytic, alpha polypeptide 0.951
Ctnnb1 catenin (cadherin associated protein), beta 1 0.939
Map3k7 mitogen-activated protein kinase kinase kinase 7 0.933
Bcl2l11 BCL2-like 11 (apoptosis facilitator) 0.917
Atf2 activating transcription factor 2 0.906
Cd44 CD44 antigen 0.902
Kras v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog 0.894
Nfe2l2 nuclear factor, erythroid derived 2, like 2 0.888
Tlr4 toll-like receptor 4 0.887
Ccnd1 cyclin D1 0.886
Cav1 caveolin 1, caveolae protein 0.880
Cry2 cryptochrome 2 (photolyase-like) 0.872
Prkce protein kinase C, epsilon 0.864
Mdm2 transformed mouse 3T3 cell double minute 2 0.863
Ccl2 chemokine (C-C motif) ligand 2 0.851
Skil SKI-like 0.826
Cdkn1b cyclin-dependent kinase inhibitor 1B 0.816
C3ar1 complement component 3a receptor 1 0.808
Prnp prion protein 0.807
Lepr leptin receptor 0.803
Grin1 glutamate receptor, ionotropic, NMDA1 (zeta 1) 0.796
Tnf tumor necrosis factor 0.794
Tgfbr2 transforming growth factor, beta receptor II 0.794
Tnfrsf1a tumor necrosis factor receptor superfamily, member 1a 0.788
Rac1 RAS-related C3 botulinum substrate 1 0.782
Ror2 receptor tyrosine kinase-like orphan receptor 2 0.775
Il6st interleukin 6 signal transducer 0.766
Igh immunoglobulin heavy chain complex 0.763
Dvl1 dishevelled, dsh homolog 1 (Drosophila) 0.743
Sqstm1 sequestosome 1 0.730
Fzd8 frizzled homolog 8 (Drosophila) 0.726
Irs1 insulin receptor substrate 1 0.721
Brca1 breast cancer 1 0.706
Per2 period homolog 2 (Drosophila) 0.700
Dvl2 dishevelled 2, dsh homolog (Drosophila) 0.694
Mdm4 transformed mouse 3T3 cell double minute 4 0.692
Mef2a myocyte enhancer factor 2A 0.686
Wnt5a wingless-related MMTV integration site 5A 0.659
Tnfaip3 tumor necrosis factor, alpha-induced protein 3 0.655
Klf7 Kruppel-like factor 7 (ubiquitous) 0.654
Mtor mechanistic target of rapamycin (serine/threonine kinase) 0.645
Cdc42 cell division cycle 42 homolog (S. cerevisiae) 0.640
Axin1 axin 1 0.631
Cxcl13 chemokine (C-X-C motif) ligand 13 0.617
Hsp90aa1 heat shock protein 90, alpha (cytosolic), class A member 1 0.610
Shc1 src homology 2 domain-containing transforming protein C1 0.604
Bax BCL2-associated X protein 0.595
Msr1 macrophage scavenger receptor 1 0.594
Ccl4 chemokine (C-C motif) ligand 4 0.588
Dvl3 dishevelled 3, dsh homolog (Drosophila) 0.580
Stat3 signal transducer and activator of transcription 3 0.578
Nfkb2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100 0.571
Wnt3a wingless-related MMTV integration site 3A 0.553
Brca2 breast cancer 2 0.540
Wdr26 WD repeat domain 26 0.536
Sema6a sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A 0.536
Ndel1 nuclear distribution gene E-like homolog 1 (A. nidulans) 0.532
Nr2f2 nuclear receptor subfamily 2, group F, member 2 0.526
Pdgfra platelet derived growth factor receptor, alpha polypeptide 0.513
Smad1 MAD homolog 1 (Drosophila) 0.507
Fbxw7 F-box and WD-40 domain protein 7 0.506
Nfatc3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 0.497
Mcl1 myeloid cell leukemia sequence 1 0.495
Enah enabled homolog (Drosophila) 0.494
Traf2 TNF receptor-associated factor 2 0.493
Cry1 cryptochrome 1 (photolyase-like) 0.492
Map3k14 mitogen-activated protein kinase kinase kinase 14 0.484
Usp8 ubiquitin specific peptidase 8 0.481
Rb1 retinoblastoma 1 0.480
Grb10 growth factor receptor bound protein 10 0.477
Tnfrsf11a tumor necrosis factor receptor superfamily, member 11a 0.475
Gsk3b glycogen synthase kinase 3 beta 0.474
Qk quaking 0.473
Fgfr1 fibroblast growth factor receptor 1 0.473
Klk1b11 kallikrein 1-related peptidase b11 0.473
Csf1 colony stimulating factor 1 (macrophage) 0.473
Kif1b kinesin family member 1B 0.470
Met met proto-oncogene 0.465
Arntl aryl hydrocarbon receptor nuclear translocator-like 0.463
Smad7 MAD homolog 7 (Drosophila) 0.449
Fasl Fas ligand (TNF superfamily, member 6) 0.445
Rab3il1 RAB3A interacting protein (rabin3)-like 1 0.443
Cftr cystic fibrosis transmembrane conductance regulator homolog 0.442
D4Wsu53e DNA segment, Chr 4, Wayne State University 53, expressed 0.440
Ephb2 Eph receptor B2 0.437
Dicer1 Dicer1, Dcr-1 homolog (Drosophila) 0.431
Ppp1cc protein phosphatase 1, catalytic subunit, gamma isoform 0.428
Apoe apolipoprotein E 0.428
Ccl12 chemokine (C-C motif) ligand 12 0.427
Sfrp2 secreted frizzled-related protein 2 0.422
Clec4d C-type lectin domain family 4, member d 0.418
Ccr1 chemokine (C-C motif) receptor 1 0.417
Loading network...
Saccharomyces cerevisiae
Name Description Probability Func Analog Organism
KSP1 Ksp1p 0.962
BCK1 Bck1p 0.954
TOR1 Tor1p 0.822
PPH21 Pph21p 0.747
CTR9 Ctr9p 0.663
PPH3 Pph3p 0.661
CDC55 Cdc55p 0.641
PMT1 Pmt1p 0.532
SSK2 Ssk2p 0.484
PSY2 Psy2p 0.356
MIG1 Mig1p 0.327
CKA1 Cka1p 0.290
PAF1 Paf1p 0.288
MON1 Mon1p 0.245
KIC1 Kic1p 0.233
KOG1 Kog1p 0.229
NBP2 Nbp2p 0.229
ATG13 Atg13p 0.227
YPT1 Ypt1p 0.225
TIP41 Tip41p 0.218
CTK1 Ctk1p 0.184
UFO1 Ufo1p 0.184
YMR102C hypothetical protein 0.175
PBS2 Pbs2p 0.167
YKR015C hypothetical protein 0.165
STE20 Ste20p 0.157
SAP185 Sap185p 0.150
MIG2 Mig2p 0.144
YJU2 Yju2p 0.140
SIN4 Sin4p 0.140
RGD1 Rgd1p 0.132
HOG1 Hog1p 0.132
RPN14 Rpn14p 0.120
FMP48 Fmp48p 0.118
PMT2 Pmt2p 0.117
VID24 Vid24p 0.117
RTF1 Rtf1p 0.116
UBC13 Ubc13p 0.114
BCY1 Bcy1p 0.114
RLM1 Rlm1p 0.113
DBF2 Dbf2p 0.112
MET4 Met4p 0.108
NTO1 Nto1p 0.108
HSL1 Hsl1p 0.107
CAT8 Cat8p 0.106
ADR1 Adr1p 0.105
STE7 Ste7p 0.104
HRK1 Hrk1p 0.104
LHS1 Lhs1p 0.103
GBP2 Gbp2p 0.103
RAD30 Rad30p 0.102
ATG21 Atg21p 0.101
PCL8 Pcl8p 0.097
HAL5 Hal5p 0.093
SKO1 Sko1p 0.092
HOS2 Hos2p 0.090
SSN3 Ssn3p 0.087
HSV2 Hsv2p 0.086
RAD27 Rad27p 0.086
TOM1 Tom1p 0.084
FUS3 Fus3p 0.084
ATG4 Atg4p 0.083
YPL150W hypothetical protein 0.083
POL30 Pol30p 0.083
YAK1 Yak1p 0.082
MOB1 Mob1p 0.081
MDS3 Mds3p 0.081
HOS4 Hos4p 0.081
MNN9 Mnn9p 0.081
SPT16 Spt16p 0.080
CKB1 Ckb1p 0.078
SKS1 Sks1p 0.078
KDX1 Kdx1p 0.078
PSY4 Psy4p 0.077
OPY2 Opy2p 0.077
YKR075C hypothetical protein 0.075
VPS75 Vps75p 0.072
MNL1 Mnl1p 0.072
GET1 Get1p 0.071
YHB1 Yhb1p 0.071
RAD52 Rad52p 0.071
IOC4 Ioc4p 0.071
YPT31 Ypt31p 0.071
FUN12 Fun12p 0.070
CUP9 Cup9p 0.070
MNN2 Mnn2p 0.070
PCL2 Pcl2p 0.069
SPT15 Spt15p 0.069
MNR2 Mnr2p 0.069
ROX1 Rox1p 0.068
RFA2 Rfa2p 0.068
FKH1 Fkh1p 0.068
RTS1 Rts1p 0.068
SNF4 Snf4p 0.068
GAT2 Gat2p 0.066
PIL1 Pil1p 0.066
PHO81 Pho81p 0.064
ZDS1 Zds1p 0.063
MHP1 Mhp1p 0.061
MGS1 Mgs1p 0.060