|
|
positive regulation of pathway restricted smad protein phosphorylation
|
GO:0010862 |
22 |
1.000
|
Mouse |
|
|
positive regulation of odontogenesis
|
GO:0042482 |
3 |
1.000
|
|
|
|
regulation of pathway restricted smad protein phosphorylation
|
GO:0060393 |
34 |
0.998
|
Mouse |
|
|
negative regulation of trophoblast cell migration
|
GO:1901164 |
3 |
0.996
|
|
|
|
cardiac muscle cell fate commitment
|
GO:0060923 |
4 |
0.990
|
|
|
|
atrial septum primum morphogenesis
|
GO:0003289 |
1 |
0.988
|
|
|
|
positive regulation of cardioblast differentiation
|
GO:0051891 |
2 |
0.969
|
|
|
|
positive regulation of fibroblast migration
|
GO:0010763 |
3 |
0.968
|
|
|
|
negative regulation of chorionic trophoblast cell proliferation
|
GO:1901383 |
2 |
0.962
|
|
|
|
chorionic trophoblast cell proliferation
|
GO:0097360 |
2 |
0.960
|
|
|
|
negative regulation of chondrocyte proliferation
|
GO:1902731 |
1 |
0.953
|
|
|
|
chondrocyte development
|
GO:0002063 |
1 |
0.951
|
|
|
|
mitral valve development
|
GO:0003174 |
3 |
0.950
|
|
|
|
patterning of blood vessels
|
GO:0001569 |
2 |
0.939
|
|
|
|
pathway restricted smad protein phosphorylation
|
GO:0060389 |
38 |
0.935
|
Mouse |
|
|
regulation of smad protein import into nucleus
|
GO:0060390 |
10 |
0.899
|
Mouse |
|
|
negative regulation of epithelial cell migration
|
GO:0010633 |
38 |
0.888
|
|
|
|
cardiac endothelial cell differentiation
|
GO:0003348 |
2 |
0.875
|
|
|
|
regulation of chorionic trophoblast cell proliferation
|
GO:1901382 |
2 |
0.865
|
|
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
303 |
0.864
|
|
|
|
regulation of lung blood pressure
|
GO:0014916 |
1 |
0.864
|
|
|
|
positive regulation of trophoblast cell migration
|
GO:1901165 |
2 |
0.849
|
|
|
|
regulation of cardiac muscle cell proliferation
|
GO:0060043 |
4 |
0.817
|
|
|
|
endocardial cell fate commitment
|
GO:0060957 |
1 |
0.813
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.811
|
|
|
|
endocardial cushion cell differentiation
|
GO:0061443 |
1 |
0.810
|
|
|
|
negative regulation of cardiac muscle tissue development
|
GO:0055026 |
7 |
0.800
|
|
|
|
negative regulation of striated muscle tissue development
|
GO:0045843 |
11 |
0.799
|
|
|
|
atrial septum morphogenesis
|
GO:0060413 |
5 |
0.798
|
|
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.779
|
Mouse Rat |
|
|
organ formation
|
GO:0048645 |
3 |
0.774
|
|
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
0.770
|
|
|
|
regulation of branching involved in ureteric bud morphogenesis
|
GO:0090189 |
3 |
0.770
|
|
|
|
positive regulation of aldosterone metabolic process
|
GO:0032346 |
2 |
0.746
|
|
|
|
regulation of odontogenesis
|
GO:0042481 |
4 |
0.738
|
|
|
|
connective tissue development
|
GO:0061448 |
39 |
0.737
|
Zebrafish |
|
|
activation of protein kinase activity
|
GO:0032147 |
90 |
0.725
|
Rat |
|
|
regulation of determination of dorsal identity
|
GO:2000015 |
2 |
0.706
|
|
|
|
cellular response to transforming growth factor beta stimulus
|
GO:0071560 |
94 |
0.689
|
|
|
|
response to wounding
|
GO:0009611 |
168 |
0.681
|
Rat |
|
|
muscle cell proliferation
|
GO:0033002 |
35 |
0.673
|
|
|
|
blood circulation
|
GO:0008015 |
113 |
0.669
|
|
|
|
regulation of bone mineralization
|
GO:0030500 |
29 |
0.666
|
|
|
|
negative regulation of developmental process
|
GO:0051093 |
247 |
0.660
|
|
|
|
regulation of heart growth
|
GO:0060420 |
4 |
0.634
|
|
|
|
wound healing
|
GO:0042060 |
115 |
0.631
|
Rat |
|
|
bone mineralization
|
GO:0030282 |
34 |
0.622
|
|
|
|
negative regulation of locomotion
|
GO:0040013 |
118 |
0.622
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.619
|
Rat |
|
|
epithelial to mesenchymal transition
|
GO:0001837 |
48 |
0.618
|
|
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
125 |
0.616
|
|
|
|
craniofacial suture morphogenesis
|
GO:0097094 |
3 |
0.605
|
Rat |
|
|
regulation of cell migration
|
GO:0030334 |
289 |
0.603
|
|
|
|
negative regulation of muscle tissue development
|
GO:1901862 |
11 |
0.586
|
|
|
|
negative regulation of cellular component movement
|
GO:0051271 |
106 |
0.584
|
|
|
|
biomineral tissue development
|
GO:0031214 |
39 |
0.583
|
|
|
|
positive regulation of biomineral tissue development
|
GO:0070169 |
20 |
0.581
|
|
|
|
anatomical structure formation involved in morphogenesis
|
GO:0048646 |
284 |
0.577
|
|
|
|
stem cell development
|
GO:0048864 |
69 |
0.575
|
|
|
|
cardiac atrium development
|
GO:0003230 |
10 |
0.570
|
|
|
|
cell development
|
GO:0048468 |
328 |
0.569
|
|
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.561
|
Rat |
|
|
epithelial cell fate commitment
|
GO:0072148 |
3 |
0.556
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
281 |
0.550
|
Mouse |
|
|
cartilage development involved in endochondral bone morphogenesis
|
GO:0060351 |
2 |
0.543
|
|
|
|
regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090092 |
90 |
0.538
|
Mouse Rat |
|
|
transforming growth factor beta receptor signaling pathway
|
GO:0007179 |
76 |
0.537
|
|
|
|
negative regulation of blood pressure
|
GO:0045776 |
3 |
0.537
|
|
|
|
positive regulation of steroid hormone biosynthetic process
|
GO:0090031 |
2 |
0.533
|
|
|
|
cardiac epithelial to mesenchymal transition
|
GO:0060317 |
3 |
0.531
|
|
|
|
endocardial cushion development
|
GO:0003197 |
3 |
0.530
|
|
|
|
atrioventricular valve morphogenesis
|
GO:0003181 |
2 |
0.529
|
|
|
|
mitral valve morphogenesis
|
GO:0003183 |
2 |
0.526
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.522
|
Mouse Rat |
|
|
response to growth factor
|
GO:0070848 |
205 |
0.521
|
|
|
|
positive regulation of ossification
|
GO:0045778 |
32 |
0.519
|
|
|
|
regulation of cellular component movement
|
GO:0051270 |
334 |
0.518
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
190 |
0.506
|
Rat |
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
313 |
0.500
|
Mouse Rat |
|
|
regulation of locomotion
|
GO:0040012 |
329 |
0.497
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.496
|
Rat |
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
181 |
0.494
|
|
|
|
regulation of cell motility
|
GO:2000145 |
299 |
0.491
|
|
|
|
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090101 |
45 |
0.483
|
Rat |
|
|
glial cell migration
|
GO:0008347 |
4 |
0.481
|
|
|
|
cell substrate adhesion
|
GO:0031589 |
132 |
0.458
|
|
|
|
negative regulation of endothelial cell migration
|
GO:0010596 |
29 |
0.457
|
|
|
|
mesenchymal cell development
|
GO:0014031 |
50 |
0.453
|
|
|
|
positive regulation of osteoblast differentiation
|
GO:0045669 |
23 |
0.449
|
|
|
|
regulation of cell growth
|
GO:0001558 |
135 |
0.448
|
|
|
|
organ morphogenesis
|
GO:0009887 |
147 |
0.447
|
|
|
|
regulation of cell adhesion
|
GO:0030155 |
166 |
0.446
|
|
|
|
negative regulation of cell migration
|
GO:0030336 |
102 |
0.440
|
|
|
|
positive regulation of hair follicle maturation
|
GO:0048818 |
2 |
0.439
|
|
|
|
ossification
|
GO:0001503 |
121 |
0.438
|
|
|
|
muscle cell fate commitment
|
GO:0042693 |
4 |
0.430
|
|
|
|
positive regulation of bone mineralization
|
GO:0030501 |
19 |
0.430
|
|
|
|
blood vessel development
|
GO:0001568 |
172 |
0.424
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
268 |
0.415
|
|
|
|
regulation of cellular response to growth factor stimulus
|
GO:0090287 |
76 |
0.414
|
Rat |
|
|
negative regulation of cell differentiation
|
GO:0045596 |
171 |
0.414
|
|
|
|
positive regulation of cell migration
|
GO:0030335 |
172 |
0.411
|
|
|
|
regulation of transforming growth factor beta receptor signaling pathway
|
GO:0017015 |
48 |
0.405
|
Rat |
|
|
regulation of cell morphogenesis involved in differentiation
|
GO:0010769 |
83 |
0.404
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
204 |
0.398
|
Rat |
|
|
myeloid dendritic cell differentiation
|
GO:0043011 |
3 |
0.398
|
|
|
|
mapk cascade
|
GO:0000165 |
288 |
0.397
|
Rat |
|
|
positive regulation of phosphatidylinositol 3 kinase signaling
|
GO:0014068 |
28 |
0.395
|
|
|
|
determination of dorsal identity
|
GO:0048263 |
4 |
0.394
|
|
|
|
biological adhesion
|
GO:0022610 |
331 |
0.392
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.392
|
|
|
|
cell matrix adhesion
|
GO:0007160 |
85 |
0.385
|
|
|
|
determination of dorsal ventral asymmetry
|
GO:0048262 |
4 |
0.384
|
|
|
|
atrioventricular valve development
|
GO:0003171 |
3 |
0.380
|
|
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.376
|
|
|
|
system process
|
GO:0003008 |
349 |
0.370
|
|
|
|
mesenchymal cell differentiation
|
GO:0048762 |
52 |
0.370
|
|
|
|
response to lipid
|
GO:0033993 |
206 |
0.369
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
175 |
0.367
|
|
|
|
mesenchyme development
|
GO:0060485 |
59 |
0.363
|
|
|
|
skeletal system development
|
GO:0001501 |
79 |
0.358
|
Zebrafish Rat |
|
|
negative regulation of cell growth
|
GO:0030308 |
83 |
0.354
|
|
|
|
epithelium development
|
GO:0060429 |
227 |
0.351
|
|
|
|
positive regulation of stress activated mapk cascade
|
GO:0032874 |
60 |
0.350
|
|
|
|
endothelial cell fate commitment
|
GO:0060839 |
3 |
0.347
|
|
|
|
cell adhesion
|
GO:0007155 |
325 |
0.343
|
|
|
|
regulation of endothelial cell migration
|
GO:0010594 |
67 |
0.343
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
228 |
0.335
|
Mouse Rat |
|
|
cellular ion homeostasis
|
GO:0006873 |
168 |
0.334
|
|
|
|
septum primum development
|
GO:0003284 |
1 |
0.333
|
|
|
|
myeloid dendritic cell activation
|
GO:0001773 |
4 |
0.332
|
|
|
|
tissue morphogenesis
|
GO:0048729 |
96 |
0.330
|
|
|
|
actin filament based process
|
GO:0030029 |
224 |
0.328
|
|
|
|
positive regulation of cellular component movement
|
GO:0051272 |
181 |
0.327
|
|
|
|
regeneration
|
GO:0031099 |
4 |
0.326
|
|
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.325
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
190 |
0.324
|
Rat |
|
|
common partner smad protein phosphorylation
|
GO:0007182 |
3 |
0.320
|
|
|
|
negative regulation of cell substrate adhesion
|
GO:0010812 |
24 |
0.319
|
|
|
|
lipid metabolic process
|
GO:0006629 |
381 |
0.317
|
|
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
286 |
0.315
|
|
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.313
|
Mouse |
|
|
cellular macromolecular complex assembly
|
GO:0034622 |
324 |
0.313
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
235 |
0.312
|
|
|
|
negative regulation of axon extension
|
GO:0030517 |
2 |
0.309
|
|
|
|
regulation of smooth muscle cell proliferation
|
GO:0048660 |
28 |
0.308
|
|
|
|
circulatory system process
|
GO:0003013 |
113 |
0.307
|
|
|
|
response to hormone
|
GO:0009725 |
175 |
0.301
|
|
|
|
regulation of stress activated protein kinase signaling cascade
|
GO:0070302 |
85 |
0.300
|
|
|
|
vasculature development
|
GO:0001944 |
181 |
0.298
|
|
|
|
regulation of epithelial to mesenchymal transition
|
GO:0010717 |
37 |
0.298
|
|
|
|
regulation of stem cell differentiation
|
GO:2000736 |
56 |
0.297
|
|
|
|
substrate dependent cerebral cortex tangential migration
|
GO:0021825 |
2 |
0.296
|
|
|
|
regulation of ossification
|
GO:0030278 |
58 |
0.294
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
262 |
0.293
|
Rat |
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.292
|
|
|
|
cardiac muscle tissue development
|
GO:0048738 |
39 |
0.291
|
|
|
|
regulation of systemic arterial blood pressure
|
GO:0003073 |
19 |
0.290
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
125 |
0.289
|
Mouse |
|
|
cardiac muscle cell proliferation
|
GO:0060038 |
6 |
0.289
|
|
|
|
response to transforming growth factor beta
|
GO:0071559 |
94 |
0.286
|
|
|
|
cellular response to external stimulus
|
GO:0071496 |
111 |
0.286
|
|
|
|
protein localization to organelle
|
GO:0033365 |
280 |
0.283
|
Mouse Rat |
|
|
response to ketone
|
GO:1901654 |
19 |
0.278
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.278
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.277
|
|
|
|
positive regulation of locomotion
|
GO:0040017 |
186 |
0.276
|
|
|
|
positive regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090100 |
41 |
0.275
|
Mouse |
|
|
negative regulation of cardiac muscle cell proliferation
|
GO:0060044 |
2 |
0.273
|
|
|
|
negative regulation of systemic arterial blood pressure
|
GO:0003085 |
1 |
0.273
|
|
|
|
negative regulation of axonogenesis
|
GO:0050771 |
4 |
0.272
|
|
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
119 |
0.271
|
Rat |
|
|
striated muscle cell proliferation
|
GO:0014855 |
7 |
0.270
|
|
|
|
endochondral bone morphogenesis
|
GO:0060350 |
3 |
0.264
|
|
|
|
fibroblast migration
|
GO:0010761 |
7 |
0.258
|
|
|
|
cellular response to organic cyclic compound
|
GO:0071407 |
127 |
0.258
|
|
|
|
regulation of cardiac muscle tissue growth
|
GO:0055021 |
4 |
0.257
|
|
|
|
negative regulation of growth
|
GO:0045926 |
97 |
0.256
|
|
|
|
cellular protein complex assembly
|
GO:0043623 |
188 |
0.253
|
|
|
|
negative regulation of axon guidance
|
GO:1902668 |
1 |
0.253
|
|
|
|
negative regulation of cell motility
|
GO:2000146 |
104 |
0.248
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
7 |
0.246
|
|
|
|
positive regulation of cell differentiation
|
GO:0045597 |
211 |
0.246
|
|
|
|
epithelial cell proliferation
|
GO:0050673 |
128 |
0.245
|
|
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.245
|
Mouse |
|
|
regulation of stress activated mapk cascade
|
GO:0032872 |
84 |
0.244
|
|
|
|
regulation of axon guidance
|
GO:1902667 |
3 |
0.244
|
|
|
|
motor neuron axon guidance
|
GO:0008045 |
2 |
0.242
|
|
|
|
positive regulation of endothelial cell migration
|
GO:0010595 |
39 |
0.241
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
249 |
0.241
|
Mouse Rat |
|
|
endothelial cell migration
|
GO:0043542 |
86 |
0.241
|
|
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.238
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.238
|
Rat |
|
|
negative regulation of muscle organ development
|
GO:0048635 |
12 |
0.237
|
|
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.237
|
|
|
|
gastrulation
|
GO:0007369 |
51 |
0.235
|
|
|
|
epithelium migration
|
GO:0090132 |
119 |
0.235
|
|
|
|
positive regulation of cell motility
|
GO:2000147 |
177 |
0.234
|
|
|
|
cardiac atrium morphogenesis
|
GO:0003209 |
7 |
0.231
|
|
|
|
circulatory system development
|
GO:0072359 |
262 |
0.231
|
|
|
|
regulation of chemotaxis
|
GO:0050920 |
74 |
0.229
|
|
|
|
negative regulation of macrophage cytokine production
|
GO:0010936 |
3 |
0.229
|
|
|
|
regulation of extrinsic apoptotic signaling pathway
|
GO:2001236 |
85 |
0.229
|
|
|
|
regulation of phosphatidylinositol 3 kinase signaling
|
GO:0014066 |
35 |
0.226
|
|
|
|
regulation of blood vessel endothelial cell migration
|
GO:0043535 |
30 |
0.225
|
|
|
|
positive regulation of cell proliferation
|
GO:0008284 |
301 |
0.224
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.223
|
Mouse Rat |
|
|
lens development in camera type eye
|
GO:0002088 |
2 |
0.221
|
|
|
|
chondrocyte differentiation involved in endochondral bone morphogenesis
|
GO:0003413 |
1 |
0.221
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
162 |
0.218
|
|
|
|
regulation of biomineral tissue development
|
GO:0070167 |
31 |
0.217
|
|
|
|
regulation of response to external stimulus
|
GO:0032101 |
222 |
0.216
|
|
|
|
positive regulation of mesonephros development
|
GO:0061213 |
2 |
0.215
|
|
|
|
mesonephros development
|
GO:0001823 |
17 |
0.215
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
136 |
0.214
|
Mouse Rat |
|
|
positive regulation of transferase activity
|
GO:0051347 |
227 |
0.210
|
Rat |
|
|
metal ion transport
|
GO:0030001 |
272 |
0.209
|
|
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.208
|
|
|
|
regulation of map kinase activity
|
GO:0043405 |
108 |
0.208
|
Rat |
|
|
endocardium development
|
GO:0003157 |
2 |
0.207
|
|
|
|
embryonic cranial skeleton morphogenesis
|
GO:0048701 |
6 |
0.207
|
Rat |
|
|
morphogenesis of a branching structure
|
GO:0001763 |
21 |
0.207
|
|
|
|
endocardial cell differentiation
|
GO:0060956 |
2 |
0.204
|
|
|
|
ameboidal type cell migration
|
GO:0001667 |
135 |
0.204
|
|
|
|
digestive tract morphogenesis
|
GO:0048546 |
56 |
0.203
|
|
|
|
regulation of secretion by cell
|
GO:1903530 |
177 |
0.203
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
211 |
0.202
|
|
|
|
positive regulation of protein transport
|
GO:0051222 |
135 |
0.202
|
|
|
|
chondrocyte proliferation
|
GO:0035988 |
4 |
0.201
|
|
|
|
epithelial cell differentiation
|
GO:0030855 |
141 |
0.201
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.200
|
|
|
|
positive regulation of isotype switching to iga isotypes
|
GO:0048298 |
2 |
0.197
|
|
|
|
negative regulation of epithelial cell proliferation
|
GO:0050680 |
48 |
0.197
|
|
|
|
negative regulation of cell adhesion
|
GO:0007162 |
64 |
0.197
|
|
|
|
regulation of striated muscle tissue development
|
GO:0016202 |
26 |
0.196
|
|
|
|
salivary gland morphogenesis
|
GO:0007435 |
4 |
0.196
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.195
|
|
|
|
regulation of tolerance induction
|
GO:0002643 |
4 |
0.192
|
|
|
|
regulation of cardioblast differentiation
|
GO:0051890 |
4 |
0.191
|
|
|
|
endothelial cell proliferation
|
GO:0001935 |
65 |
0.190
|
|
|
|
regulation of epithelial cell proliferation
|
GO:0050678 |
113 |
0.190
|
|
|
|
regulation of activin receptor signaling pathway
|
GO:0032925 |
14 |
0.190
|
|
|
|
nervous system development
|
GO:0007399 |
293 |
0.189
|
|
|
|
endoderm development
|
GO:0007492 |
33 |
0.188
|
|
|
|
chemotaxis
|
GO:0006935 |
157 |
0.187
|
|
|
|
positive regulation of nucleocytoplasmic transport
|
GO:0046824 |
54 |
0.186
|
Mouse |
|
|
palate development
|
GO:0060021 |
13 |
0.186
|
Mouse |
|
|
tube morphogenesis
|
GO:0035239 |
95 |
0.183
|
|
|
|
positive regulation of sequence specific dna binding transcription factor activity
|
GO:0051091 |
131 |
0.182
|
|
|
|
morphogenesis of an epithelial sheet
|
GO:0002011 |
12 |
0.179
|
|
|
|
positive regulation of aldosterone biosynthetic process
|
GO:0032349 |
2 |
0.178
|
|
|
|
calcium ion homeostasis
|
GO:0055074 |
122 |
0.178
|
|
|
|
regulation of hormone secretion
|
GO:0046883 |
57 |
0.178
|
|
|
|
mammary gland morphogenesis
|
GO:0060443 |
2 |
0.177
|
|
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
317 |
0.177
|
|
|
|
negative regulation of alkaline phosphatase activity
|
GO:0010693 |
2 |
0.176
|
|
|
|
single organism carbohydrate metabolic process
|
GO:0044723 |
193 |
0.175
|
|
|
|
regulation of myoblast differentiation
|
GO:0045661 |
12 |
0.175
|
|
|
|
extracellular matrix organization
|
GO:0030198 |
41 |
0.175
|
|
|
|
heart development
|
GO:0007507 |
95 |
0.175
|
|
|
|
positive regulation of reactive oxygen species metabolic process
|
GO:2000379 |
24 |
0.173
|
|
|
|
extracellular structure organization
|
GO:0043062 |
41 |
0.173
|
|
|
|
cerebral cortex cell migration
|
GO:0021795 |
3 |
0.172
|
|
|
|
positive regulation of secretion by cell
|
GO:1903532 |
108 |
0.172
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
174 |
0.172
|
|
|
|
taxis
|
GO:0042330 |
157 |
0.172
|
|
|
|
phosphatidylinositol mediated signaling
|
GO:0048015 |
55 |
0.170
|
|
|
|
immune response
|
GO:0006955 |
307 |
0.169
|
|
|
|
positive regulation of cell morphogenesis involved in differentiation
|
GO:0010770 |
50 |
0.169
|
|
|
|
defense response
|
GO:0006952 |
315 |
0.168
|
|
|
|
osteoblast differentiation
|
GO:0001649 |
92 |
0.168
|
|
|
|
cellular response to glucocorticoid stimulus
|
GO:0071385 |
4 |
0.168
|
|
|
|
regulation of muscle tissue development
|
GO:1901861 |
26 |
0.167
|
|
|
|
regulation of actin filament based process
|
GO:0032970 |
141 |
0.167
|
|
|
|
regulation of axon extension involved in axon guidance
|
GO:0048841 |
2 |
0.167
|
|
|
|
ion homeostasis
|
GO:0050801 |
230 |
0.165
|
|
|
|
regulation of cell substrate adhesion
|
GO:0010810 |
68 |
0.163
|
|
|
|
tube development
|
GO:0035295 |
125 |
0.163
|
Mouse Rat |
|
|
positive regulation of blood vessel endothelial cell migration
|
GO:0043536 |
16 |
0.163
|
|
|
|
cell growth
|
GO:0016049 |
160 |
0.161
|
|
|
|
positive regulation of transport
|
GO:0051050 |
336 |
0.159
|
|
|
|
organophosphate biosynthetic process
|
GO:0090407 |
163 |
0.159
|
|
|
|
cell morphogenesis involved in differentiation
|
GO:0000904 |
144 |
0.157
|
|
|
|
cation homeostasis
|
GO:0055080 |
189 |
0.155
|
|
|
|
epithelial tube morphogenesis
|
GO:0060562 |
38 |
0.154
|
|
|
|
regulation of t cell activation
|
GO:0050863 |
77 |
0.153
|
|
|
|
regulation of muscle organ development
|
GO:0048634 |
27 |
0.153
|
|
|
|
blastoderm segmentation
|
GO:0007350 |
2 |
0.153
|
|
|
|
epithelial cell migration
|
GO:0010631 |
119 |
0.152
|
|
|
|
cell chemotaxis
|
GO:0060326 |
112 |
0.151
|
|
|
|
focal adhesion assembly
|
GO:0048041 |
30 |
0.151
|
|
|
|
embryonic morphogenesis
|
GO:0048598 |
85 |
0.151
|
Rat |
|
|
response to steroid hormone
|
GO:0048545 |
80 |
0.150
|
|
|
|
morphogenesis of an epithelium
|
GO:0002009 |
60 |
0.150
|
|
|
|
growth
|
GO:0040007 |
202 |
0.149
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
179 |
0.149
|
Rat |
|
|
positive regulation of mesenchymal cell proliferation
|
GO:0002053 |
2 |
0.147
|
|
|
|
regulation of epithelial cell migration
|
GO:0010632 |
93 |
0.147
|
|
|
|
positive regulation of cytokine production
|
GO:0001819 |
167 |
0.146
|
|
|
|
positive regulation of protein import into nucleus
|
GO:0042307 |
46 |
0.146
|
Mouse |
|
|
angiogenesis
|
GO:0001525 |
147 |
0.145
|
|
|
|
hemopoiesis
|
GO:0030097 |
180 |
0.145
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
246 |
0.145
|
Mouse Rat |
|
|
smooth muscle cell proliferation
|
GO:0048659 |
28 |
0.142
|
|
|
|
regulation of secretion
|
GO:0051046 |
194 |
0.141
|
|
|
|
positive regulation of immunoglobulin mediated immune response
|
GO:0002891 |
4 |
0.141
|
|
|
|
regulation of adherens junction organization
|
GO:1903391 |
21 |
0.140
|
|
|
|
cardiovascular system development
|
GO:0072358 |
262 |
0.140
|
|
|
|
positive regulation of intracellular protein transport
|
GO:0090316 |
76 |
0.138
|
Mouse |
|
|
positive regulation of protein kinase b signaling
|
GO:0051897 |
42 |
0.138
|
|
|
|
regulation of erk1 and erk2 cascade
|
GO:0070372 |
99 |
0.138
|
|
|
|
positive regulation of epithelial to mesenchymal transition
|
GO:0010718 |
22 |
0.137
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
119 |
0.137
|
|
|
|
regulation of hormone levels
|
GO:0010817 |
125 |
0.137
|
|
|
|
regulation of dna metabolic process
|
GO:0051052 |
153 |
0.136
|
|
|
|
positive regulation of stress activated protein kinase signaling cascade
|
GO:0070304 |
61 |
0.135
|
|
|
|
positive regulation of endothelial cell proliferation
|
GO:0001938 |
37 |
0.135
|
|
|
|
stress activated protein kinase signaling cascade
|
GO:0031098 |
94 |
0.135
|
|
|
|
regulation of response to wounding
|
GO:1903034 |
101 |
0.135
|
|
|
|
positive regulation of alpha beta t cell differentiation
|
GO:0046638 |
4 |
0.134
|
|
|
|
regulation of cell development
|
GO:0060284 |
161 |
0.134
|
|
|
|
positive regulation of cytosolic calcium ion concentration
|
GO:0007204 |
82 |
0.134
|
|
|
|
integrin biosynthetic process
|
GO:0045112 |
4 |
0.132
|
|
|
|
regulation of cartilage development
|
GO:0061035 |
12 |
0.132
|
Zebrafish |
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.131
|
|
|
|
activin receptor signaling pathway
|
GO:0032924 |
24 |
0.131
|
|
|
|
retina vasculature development in camera type eye
|
GO:0061298 |
3 |
0.130
|
|
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
97 |
0.130
|
|
|
|
tissue regeneration
|
GO:0042246 |
3 |
0.129
|
|
|
|
peptidyl threonine modification
|
GO:0018210 |
45 |
0.129
|
|
|
|
negative regulation of extrinsic apoptotic signaling pathway
|
GO:2001237 |
52 |
0.129
|
|
|
|
epiboly involved in wound healing
|
GO:0090505 |
8 |
0.128
|
|
|
|
neurological system process
|
GO:0050877 |
163 |
0.128
|
|
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
149 |
0.128
|
Mouse |
|
|
stem cell differentiation
|
GO:0048863 |
93 |
0.127
|
|
|
|
protein autophosphorylation
|
GO:0046777 |
123 |
0.127
|
|
|
|
regulation of reactive oxygen species metabolic process
|
GO:2000377 |
41 |
0.127
|
|
|
|
cellular homeostasis
|
GO:0019725 |
196 |
0.127
|
|
|
|
regulation of lipid kinase activity
|
GO:0043550 |
19 |
0.126
|
|
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.125
|
|
|
|
inositol lipid mediated signaling
|
GO:0048017 |
55 |
0.125
|
|
|
|
immune system development
|
GO:0002520 |
195 |
0.124
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
267 |
0.123
|
|
|
|
negative regulation of neurogenesis
|
GO:0050768 |
26 |
0.123
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
331 |
0.123
|
|
|
|
positive regulation of epithelial cell proliferation
|
GO:0050679 |
65 |
0.122
|
|
|
|
stress activated mapk cascade
|
GO:0051403 |
93 |
0.122
|
|
|
|
digestive tract development
|
GO:0048565 |
75 |
0.122
|
Rat |
|
|
response to organic cyclic compound
|
GO:0014070 |
204 |
0.121
|
|
|
|
intracellular protein transport
|
GO:0006886 |
270 |
0.121
|
Mouse Rat |
|
|
cellular chemical homeostasis
|
GO:0055082 |
180 |
0.121
|
|
|
|
odontogenesis
|
GO:0042476 |
25 |
0.120
|
|
|
|
regulation of cardiac muscle tissue development
|
GO:0055024 |
13 |
0.120
|
|
|
|
protein import
|
GO:0017038 |
130 |
0.120
|
Mouse Rat |
|
|
cytokine production
|
GO:0001816 |
247 |
0.119
|
|
|
|
positive regulation of proteolysis
|
GO:0045862 |
142 |
0.119
|
|
|
|
kidney epithelium development
|
GO:0072073 |
25 |
0.118
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
303 |
0.118
|
|
|
|
positive regulation of apoptotic signaling pathway
|
GO:2001235 |
70 |
0.118
|
|
|
|
negative regulation of immune response
|
GO:0050777 |
40 |
0.117
|
|
|
|
response to mechanical stimulus
|
GO:0009612 |
51 |
0.117
|
|
|
|
response to hypoxia
|
GO:0001666 |
96 |
0.116
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
195 |
0.116
|
Mouse |
|
|
phosphatidylinositol 3 kinase signaling
|
GO:0014065 |
48 |
0.116
|
|
|
|
negative regulation of cell development
|
GO:0010721 |
48 |
0.116
|
|
|
|
regulation of cell morphogenesis
|
GO:0022604 |
153 |
0.116
|
|
|
|
hormone transport
|
GO:0009914 |
68 |
0.115
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
412 |
0.114
|
|
|
|
regulation of osteoblast differentiation
|
GO:0045667 |
38 |
0.114
|
|
|
|
regulation of protein targeting
|
GO:1903533 |
91 |
0.114
|
Mouse |
|
|
blood vessel endothelial cell migration
|
GO:0043534 |
42 |
0.114
|
|
|
|
single organism cell adhesion
|
GO:0098602 |
179 |
0.113
|
|
|
|
negative regulation of calcium ion transport into cytosol
|
GO:0010523 |
3 |
0.112
|
|
|
|
regulation of actin cytoskeleton organization
|
GO:0032956 |
116 |
0.112
|
|
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.111
|
Mouse Rat |
|
|
branching morphogenesis of an epithelial tube
|
GO:0048754 |
19 |
0.111
|
|
|
|
muscle tissue development
|
GO:0060537 |
62 |
0.110
|
|
|
|
tissue migration
|
GO:0090130 |
119 |
0.110
|
|
|
|
regulation of smooth muscle cell differentiation
|
GO:0051150 |
3 |
0.110
|
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
172 |
0.109
|
Mouse Rat |
|
|
muscle cell differentiation
|
GO:0042692 |
63 |
0.109
|
|
|
|
cellular divalent inorganic cation homeostasis
|
GO:0072503 |
128 |
0.109
|
|
|
|
growth plate cartilage development
|
GO:0003417 |
1 |
0.109
|
|
|
|
cardiac muscle cell differentiation
|
GO:0055007 |
15 |
0.108
|
|
|
|
regulation of growth
|
GO:0040008 |
165 |
0.108
|
|
|
|
cell cell junction organization
|
GO:0045216 |
69 |
0.107
|
|
|
|
positive regulation of cell cycle process
|
GO:0090068 |
106 |
0.107
|
|
|
|
peptidyl threonine phosphorylation
|
GO:0018107 |
41 |
0.107
|
|
|
|
positive regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043280 |
69 |
0.105
|
|
|
|
response to acid chemical
|
GO:0001101 |
66 |
0.105
|
|
|
|
positive regulation of map kinase activity
|
GO:0043406 |
80 |
0.105
|
Rat |
|
|
regulation of hair follicle maturation
|
GO:0048819 |
3 |
0.104
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
411 |
0.104
|
|
|
|
sequestering of calcium ion
|
GO:0051208 |
17 |
0.104
|
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
380 |
0.103
|
|
|
|
positive regulation of lipid metabolic process
|
GO:0045834 |
50 |
0.103
|
|
|
|
positive regulation of chemotaxis
|
GO:0050921 |
57 |
0.103
|
|
|
|
bone morphogenesis
|
GO:0060349 |
10 |
0.103
|
Rat |
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
75 |
0.102
|
|
|
|
thymus development
|
GO:0048538 |
3 |
0.102
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
422 |
0.102
|
|
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
276 |
0.102
|
|
|
|
regulation of nucleocytoplasmic transport
|
GO:0046822 |
98 |
0.100
|
Mouse |
|
|
collagen fibril organization
|
GO:0030199 |
10 |
0.099
|
|
|
|
regulation of intracellular protein transport
|
GO:0033157 |
123 |
0.098
|
Mouse |
|
|
negative regulation of hydrolase activity
|
GO:0051346 |
182 |
0.098
|
|
|
|
cytosolic calcium ion homeostasis
|
GO:0051480 |
89 |
0.097
|
|
|
|
segmentation
|
GO:0035282 |
4 |
0.097
|
|
|
|
secretion
|
GO:0046903 |
254 |
0.097
|
|
|
|
positive regulation of response to external stimulus
|
GO:0032103 |
88 |
0.096
|
|
|
|
multicellular organismal metabolic process
|
GO:0044236 |
34 |
0.096
|
|
|
|
regulation of fibroblast migration
|
GO:0010762 |
7 |
0.095
|
|
|
|
regulation of neural precursor cell proliferation
|
GO:2000177 |
4 |
0.095
|
|
|
|
regulation of focal adhesion assembly
|
GO:0051893 |
20 |
0.095
|
|
|
|
cardiac muscle tissue growth
|
GO:0055017 |
6 |
0.094
|
|
|
|
positive regulation of leukocyte activation
|
GO:0002696 |
80 |
0.093
|
|
|
|
protein targeting
|
GO:0006605 |
187 |
0.093
|
Mouse Rat |
|
|
regulation of angiogenesis
|
GO:0045765 |
92 |
0.091
|
|
|
|
erk1 and erk2 cascade
|
GO:0070371 |
104 |
0.091
|
|
|
|
positive regulation of epithelial cell migration
|
GO:0010634 |
55 |
0.091
|
|
|
|
developmental cell growth
|
GO:0048588 |
18 |
0.090
|
|
|
|
cartilage development
|
GO:0051216 |
31 |
0.090
|
Zebrafish |
|
|
positive regulation of peptidase activity
|
GO:0010952 |
88 |
0.090
|
|
|
|
protein modification by small protein conjugation
|
GO:0032446 |
342 |
0.089
|
|
|
|
protein ubiquitination
|
GO:0016567 |
314 |
0.089
|
|
|
|
positive regulation of branching involved in ureteric bud morphogenesis
|
GO:0090190 |
2 |
0.088
|
|
|
|
positive regulation of behavior
|
GO:0048520 |
60 |
0.087
|
|
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
158 |
0.087
|
Mouse |
|
|
negative regulation of immune system process
|
GO:0002683 |
136 |
0.087
|
|
|
|
positive regulation of protein localization to nucleus
|
GO:1900182 |
48 |
0.086
|
Mouse |
|
|
response to sterol
|
GO:0036314 |
14 |
0.086
|
|
|
|
hematopoietic or lymphoid organ development
|
GO:0048534 |
186 |
0.086
|
|
|
|
heart morphogenesis
|
GO:0003007 |
48 |
0.086
|
|
|
|
positive regulation of angiogenesis
|
GO:0045766 |
51 |
0.085
|
|
|
|
sequestering of metal ion
|
GO:0051238 |
24 |
0.085
|
|
|
|
regulation of striated muscle cell differentiation
|
GO:0051153 |
25 |
0.085
|
|
|
|
regulation of blood pressure
|
GO:0008217 |
30 |
0.085
|
|
|
|
negative regulation of skeletal muscle tissue development
|
GO:0048642 |
2 |
0.084
|
|
|
|
cellular response to hormone stimulus
|
GO:0032870 |
125 |
0.084
|
|
|
|
regulation of binding
|
GO:0051098 |
111 |
0.084
|
|
|
|
nuclear transport
|
GO:0051169 |
179 |
0.083
|
Mouse Rat |
|
|
activation of mapk activity
|
GO:0000187 |
45 |
0.083
|
Rat |
|
|
regulation of multi organism process
|
GO:0043900 |
157 |
0.082
|
|
|
|
positive regulation of lymphocyte activation
|
GO:0051251 |
73 |
0.082
|
|
|
|
regulation of lymphocyte activation
|
GO:0051249 |
103 |
0.082
|
|
|
|
negative regulation of dna metabolic process
|
GO:0051053 |
57 |
0.082
|
|
|
|
forebrain generation of neurons
|
GO:0021872 |
3 |
0.082
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
286 |
0.081
|
|
|
|
signal release
|
GO:0023061 |
70 |
0.081
|
|
|
|
regulation of heart contraction
|
GO:0008016 |
50 |
0.080
|
|
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.080
|
Mouse |
|
|
regulation of cell matrix adhesion
|
GO:0001952 |
42 |
0.080
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
242 |
0.079
|
|
|
|
positive regulation of epithelial cell proliferation involved in wound healing
|
GO:0060054 |
3 |
0.079
|
|
|
|
lymphatic endothelial cell differentiation
|
GO:0060836 |
3 |
0.079
|
|
|
|
chemical homeostasis
|
GO:0048878 |
306 |
0.079
|
|
|
|
cellular response to dexamethasone stimulus
|
GO:0071549 |
1 |
0.078
|
|
|
|
protein import into nucleus
|
GO:0006606 |
104 |
0.078
|
Mouse Rat |
|
|
peptide secretion
|
GO:0002790 |
51 |
0.077
|
|
|
|
plasma membrane organization
|
GO:0007009 |
115 |
0.077
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
117 |
0.077
|
|
|
|
nitrogen compound transport
|
GO:0071705 |
191 |
0.077
|
|
|
|
embryonic skeletal system development
|
GO:0048706 |
13 |
0.076
|
Rat |
|
|
gland development
|
GO:0048732 |
48 |
0.076
|
|
|
|
response to decreased oxygen levels
|
GO:0036293 |
96 |
0.076
|
|
|
|
cellular hormone metabolic process
|
GO:0034754 |
41 |
0.075
|
|
|
|
negative regulation of response to external stimulus
|
GO:0032102 |
83 |
0.075
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
207 |
0.075
|
|
|
|
protein kinase b signaling
|
GO:0043491 |
69 |
0.075
|
|
|
|
adherens junction organization
|
GO:0034332 |
36 |
0.075
|
|
|
|
regulation of protein ubiquitination
|
GO:0031396 |
95 |
0.075
|
|
|
|
cell activation
|
GO:0001775 |
213 |
0.075
|
|
|
|
cell cell signaling
|
GO:0007267 |
155 |
0.074
|
|
|
|
response to bmp
|
GO:0071772 |
8 |
0.074
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
78 |
0.073
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
412 |
0.073
|
|
|
|
regulation of endothelial cell proliferation
|
GO:0001936 |
56 |
0.073
|
|
|
|
regulation of smooth muscle cell migration
|
GO:0014910 |
15 |
0.073
|
|
|
|
hair follicle morphogenesis
|
GO:0031069 |
2 |
0.073
|
|
|
|
regulation of polysaccharide biosynthetic process
|
GO:0032885 |
20 |
0.072
|
|
|
|
regulation of vasculature development
|
GO:1901342 |
97 |
0.072
|
|
|
|
bmp signaling pathway
|
GO:0030509 |
49 |
0.072
|
|
|
|
polysaccharide metabolic process
|
GO:0005976 |
33 |
0.072
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
0.072
|
|
|
|
regulation of protein kinase b signaling
|
GO:0051896 |
61 |
0.072
|
|
|
|
negative regulation of cellular response to growth factor stimulus
|
GO:0090288 |
41 |
0.072
|
Rat |
|
|
positive regulation of intracellular transport
|
GO:0032388 |
104 |
0.071
|
Mouse |
|
|
forebrain neuron development
|
GO:0021884 |
2 |
0.071
|
|
