IMP

Process View

Homo sapiens

13 genes annotated in human

palate development

The biological process whose specific outcome is the progression of the palate from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure. The palate is the partition that separates the nasal and oral cavities.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "palate development"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "palate development" (in gray)

Name	Description	Probability	Func Analog Organism
SMAD3	SMAD family member 3	0.744
TGFBR2	transforming growth factor, beta receptor II (70/80kDa)	0.718	Mouse
BMP2	bone morphogenetic protein 2	0.689
PDGFB	platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog)	0.625
COL1A1	collagen, type I, alpha 1	0.563	Human
TGFB1	transforming growth factor, beta 1	0.551
PAX3	paired box 3	0.508
NKX2-5	NK2 transcription factor related, locus 5 (Drosophila)	0.424
SMAD2	SMAD family member 2	0.373	Mouse
COL1A2	collagen, type I, alpha 2	0.355	Human
COL3A1	collagen, type III, alpha 1	0.190	Human
COL6A1	collagen, type VI, alpha 1	0.187
TGFB3	transforming growth factor, beta 3	0.186	Mouse
POU5F1	POU class 5 homeobox 1	0.156
WNT3A	wingless-type MMTV integration site family, member 3A	0.154
PPARA	peroxisome proliferator-activated receptor alpha	0.154
DDR2	discoidin domain receptor tyrosine kinase 2	0.131
SMAD4	SMAD family member 4	0.111	Mouse
MPDZ	multiple PDZ domain protein	0.107
CITED2	Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2	0.100
FOXF2	forkhead box F2	0.097
LATS2	LATS, large tumor suppressor, homolog 2 (Drosophila)	0.096
COL4A1	collagen, type IV, alpha 1	0.094
SETD8	SET domain containing (lysine methyltransferase) 8	0.086
ADAM17	ADAM metallopeptidase domain 17	0.082
UBE2I	ubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast)	0.078
COL5A2	collagen, type V, alpha 2	0.076	Human
NRP1	neuropilin 1	0.068
SPARC	secreted protein, acidic, cysteine-rich (osteonectin)	0.067
NF2	neurofibromin 2 (merlin)	0.066
FZD1	frizzled homolog 1 (Drosophila)	0.064	Mouse
PRRX2	paired related homeobox 2	0.059
THBS1	thrombospondin 1	0.057
BCL9	B-cell CLL/lymphoma 9	0.057
PDGFRB	platelet-derived growth factor receptor, beta polypeptide	0.056
SH3BP4	SH3-domain binding protein 4	0.052
COL2A1	collagen, type II, alpha 1	0.051	Human Mouse
KDM2B	lysine (K)-specific demethylase 2B	0.049
BMP4	bone morphogenetic protein 4	0.048
SMAD1	SMAD family member 1	0.045
FGF18	fibroblast growth factor 18	0.043
FOXF1	forkhead box F1	0.043	Human
PDGFA	platelet-derived growth factor alpha polypeptide	0.042
BGN	biglycan	0.040
MLLT4	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4	0.035
DAB2	disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)	0.032
PDGFRA	platelet-derived growth factor receptor, alpha polypeptide	0.032	Mouse
TBX2	T-box 2	0.032	Human
FZD10	frizzled homolog 10 (Drosophila)	0.031
TGFBR1	transforming growth factor, beta receptor 1	0.031	Mouse
WNT5A	wingless-type MMTV integration site family, member 5A	0.031
WDR5	WD repeat domain 5	0.031
FOXC2	forkhead box C2 (MFH-1, mesenchyme forkhead 1)	0.030	Human
MLL	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila)	0.030
ACAN	aggrecan	0.029
WISP1	WNT1 inducible signaling pathway protein 1	0.028
FZD8	frizzled homolog 8 (Drosophila)	0.027
WNT1	wingless-type MMTV integration site family, member 1	0.026	Human
PTPN13	protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase)	0.024
TCF4	transcription factor 4	0.024
AQP5	aquaporin 5	0.024
POSTN	periostin, osteoblast specific factor	0.023
EGR1	early growth response 1	0.023
MSX1	msh homeobox 1	0.023	Mouse
SMAD6	SMAD family member 6	0.023
HOXD13	homeobox D13	0.022
DKK1	dickkopf homolog 1 (Xenopus laevis)	0.021
SOX10	SRY (sex determining region Y)-box 10	0.021
NFIX	nuclear factor I/X (CCAAT-binding transcription factor)	0.021
PCGF1	polycomb group ring finger 1	0.021
COL13A1	collagen, type XIII, alpha 1	0.021
COL11A1	collagen, type XI, alpha 1	0.020
DLX4	distal-less homeobox 4	0.020
TWIST2	twist homolog 2 (Drosophila)	0.020
BBS10	Bardet-Biedl syndrome 10	0.019
CDH11	cadherin 11, type 2, OB-cadherin (osteoblast)	0.019
PAX2	paired box 2	0.019
JUB	jub, ajuba homolog (Xenopus laevis)	0.018
FSTL1	follistatin-like 1	0.018
AR	androgen receptor	0.018
ADAMTS2	ADAM metallopeptidase with thrombospondin type 1 motif, 2	0.018
CACNA1G	calcium channel, voltage-dependent, T type, alpha 1G subunit	0.018
GATA4	GATA binding protein 4	0.018
LRP6	low density lipoprotein receptor-related protein 6	0.018	Mouse
ZADH2	zinc binding alcohol dehydrogenase domain containing 2	0.017
TWIST1	twist homolog 1 (Drosophila)	0.017	Rat
PAX1	paired box 1	0.017
SIN3A	SIN3 homolog A, transcription regulator (yeast)	0.017
SUMO2	SMT3 suppressor of mif two 3 homolog 2 (S. cerevisiae)	0.017
PLXDC1	plexin domain containing 1	0.017
FGF8	fibroblast growth factor 8 (androgen-induced)	0.016
SHC1	SHC (Src homology 2 domain containing) transforming protein 1	0.016
SQLE	squalene epoxidase	0.016
COL5A1	collagen, type V, alpha 1	0.016	Human
LOX	lysyl oxidase	0.015
COL18A1	collagen, type XVIII, alpha 1	0.015
SC4MOL	sterol-C4-methyl oxidase-like	0.015
TP63	tumor protein p63	0.015
LAMA5	laminin, alpha 5	0.015
FOXC1	forkhead box C1	0.015	Human
ADAM12	ADAM metallopeptidase domain 12	0.015
BBS2	Bardet-Biedl syndrome 2	0.014
HOXD9	homeobox D9	0.014
MXRA5	matrix-remodelling associated 5	0.014
GSK3B	glycogen synthase kinase 3 beta	0.014
NAP1L1	nucleosome assembly protein 1-like 1	0.014
SOX1	SRY (sex determining region Y)-box 1	0.014
ELN	elastin	0.014
ONECUT1	one cut homeobox 1	0.014
LBX1	ladybird homeobox 1	0.013
TBX1	T-box 1	0.013
SIX2	SIX homeobox 2	0.013
SFRP4	secreted frizzled-related protein 4	0.013
EN1	engrailed homeobox 1	0.013
ENG	endoglin	0.013
SOX9	SRY (sex determining region Y)-box 9	0.013
CD248	CD248 molecule, endosialin	0.013
OTP	orthopedia homeobox	0.013
PBK	PDZ binding kinase	0.012
FGF3	fibroblast growth factor 3	0.012
RBBP5	retinoblastoma binding protein 5	0.012
PTMA	prothymosin, alpha	0.012
COL14A1	collagen, type XIV, alpha 1	0.012
HOXA11	homeobox A11	0.012
MSX2	msh homeobox 2	0.012
ASH2L	ash2 (absent, small, or homeotic)-like (Drosophila)	0.012
NRP2	neuropilin 2	0.012
WNT6	wingless-type MMTV integration site family, member 6	0.012	Human
BBS9	Bardet-Biedl syndrome 9	0.012
MXRA8	matrix-remodelling associated 8	0.011
KCTD1	potassium channel tetramerisation domain containing 1	0.011
WNT11	wingless-type MMTV integration site family, member 11	0.011
IHH	Indian hedgehog	0.011
ARID2	AT rich interactive domain 2 (ARID, RFX-like)	0.011
ACVR1	activin A receptor, type I	0.011
NLK	nemo-like kinase	0.011
HOXC8	homeobox C8	0.011
EDNRA	endothelin receptor type A	0.011
HTR2C	5-hydroxytryptamine (serotonin) receptor 2C	0.010
COL5A3	collagen, type V, alpha 3	0.010	Human
ST8SIA2	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2	0.010
HDAC4	histone deacetylase 4	0.010