IMP

Process View

Homo sapiens

14 genes annotated in human

response to sterol

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a sterol stimulus.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "response to sterol"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "response to sterol" (in gray)

Name	Description	Probability	Func Analog Organism
SMAD2	SMAD family member 2	0.999
SMAD7	SMAD family member 7	0.999	Human
CCR5	chemokine (C-C motif) receptor 5	0.997
SMURF2	SMAD specific E3 ubiquitin protein ligase 2	0.907
CCL4	chemokine (C-C motif) ligand 4	0.865	Human
FKBP1A	FK506 binding protein 1A, 12kDa	0.723
APBB1	amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)	0.713
TGFBR2	transforming growth factor, beta receptor II (70/80kDa)	0.678
SMAD3	SMAD family member 3	0.514	Human
NR0B1	nuclear receptor subfamily 0, group B, member 1	0.494
CXCL9	chemokine (C-X-C motif) ligand 9	0.428
TGFB1	transforming growth factor, beta 1	0.398
CCR7	chemokine (C-C motif) receptor 7	0.352	Human
ENG	endoglin	0.340
CCL8	chemokine (C-C motif) ligand 8	0.327	Human
TGFBR1	transforming growth factor, beta receptor 1	0.304
IFNG	interferon, gamma	0.294
BMP2	bone morphogenetic protein 2	0.275
CCL5	chemokine (C-C motif) ligand 5	0.272	Human Rat
CCR4	chemokine (C-C motif) receptor 4	0.264	Human
FSTL1	follistatin-like 1	0.221
CCL22	chemokine (C-C motif) ligand 22	0.212	Human
CCL3	chemokine (C-C motif) ligand 3	0.209
SMAD1	SMAD family member 1	0.203	Human
GDF5	growth differentiation factor 5	0.202
IL2RB	interleukin 2 receptor, beta	0.193
DAB2	disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)	0.190
ACVR1	activin A receptor, type I	0.161	Human
IL1B	interleukin 1, beta	0.127
CCL7	chemokine (C-C motif) ligand 7	0.114	Human
SMAD5	SMAD family member 5	0.106	Human
CCL19	chemokine (C-C motif) ligand 19	0.098	Human
CCL13	chemokine (C-C motif) ligand 13	0.094	Human
IL8	interleukin 8	0.087
TGFB3	transforming growth factor, beta 3	0.086
SMAD4	SMAD family member 4	0.085	Human
ZNF148	zinc finger protein 148	0.081
CXCR6	chemokine (C-X-C motif) receptor 6	0.072	Human
VEZF1	vascular endothelial zinc finger 1	0.069
CXCL13	chemokine (C-X-C motif) ligand 13	0.066
IRF4	interferon regulatory factor 4	0.062
PCGF2	polycomb group ring finger 2	0.057
LTA	lymphotoxin alpha (TNF superfamily, member 1)	0.056
CCL2	chemokine (C-C motif) ligand 2	0.055	Human
BMPR2	bone morphogenetic protein receptor, type II (serine/threonine kinase)	0.054	Human
CCL18	chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated)	0.053	Human
CCR2	chemokine (C-C motif) receptor 2	0.049	Human
SMURF1	SMAD specific E3 ubiquitin protein ligase 1	0.048
RERE	arginine-glutamic acid dipeptide (RE) repeats	0.047
CXXC5	CXXC finger protein 5	0.044
IL6	interleukin 6 (interferon, beta 2)	0.043
IL1R2	interleukin 1 receptor, type II	0.043
TNF	tumor necrosis factor	0.042
PRRC2B	proline-rich coiled-coil 2B	0.039
SCMH1	sex comb on midleg homolog 1 (Drosophila)	0.038
CCL11	chemokine (C-C motif) ligand 11	0.038	Human
CD40LG	CD40 ligand	0.035
SMAD6	SMAD family member 6	0.034	Human
PRKG1	protein kinase, cGMP-dependent, type I	0.032
SLAMF7	SLAM family member 7	0.031
ACVR1B	activin A receptor, type IB	0.028	Human
BAZ1A	bromodomain adjacent to zinc finger domain, 1A	0.025
SMO	smoothened homolog (Drosophila)	0.025
RGS1	regulator of G-protein signaling 1	0.025
CXCL3	chemokine (C-X-C motif) ligand 3	0.025
CCL20	chemokine (C-C motif) ligand 20	0.024	Human
CCR3	chemokine (C-C motif) receptor 3	0.024	Human
CXCR3	chemokine (C-X-C motif) receptor 3	0.023	Human
PUM1	pumilio homolog 1 (Drosophila)	0.023
IL16	interleukin 16 (lymphocyte chemoattractant factor)	0.022
CBX4	chromobox homolog 4	0.022
IDE	insulin-degrading enzyme	0.020
CXCL11	chemokine (C-X-C motif) ligand 11	0.020
KLHL24	kelch-like 24 (Drosophila)	0.019
CAPRIN2	caprin family member 2	0.019
IL2RG	interleukin 2 receptor, gamma	0.019
MMP12	matrix metallopeptidase 12 (macrophage elastase)	0.019
FCER2	Fc fragment of IgE, low affinity II, receptor for (CD23)	0.018
SC4MOL	sterol-C4-methyl oxidase-like	0.018
TNFRSF9	tumor necrosis factor receptor superfamily, member 9	0.017
FHL3	four and a half LIM domains 3	0.017
PDGFRA	platelet-derived growth factor receptor, alpha polypeptide	0.017
NRP1	neuropilin 1	0.016
INSIG1	insulin induced gene 1	0.016
CCR8	chemokine (C-C motif) receptor 8	0.015	Human
CD83	CD83 molecule	0.015
IL21R	interleukin 21 receptor	0.015
THBS1	thrombospondin 1	0.015
IL10	interleukin 10	0.015
EBI3	Epstein-Barr virus induced 3	0.014
KLRD1	killer cell lectin-like receptor subfamily D, member 1	0.014
AKT2	v-akt murine thymoma viral oncogene homolog 2	0.014
SPIN1	spindlin 1	0.014
SOX7	SRY (sex determining region Y)-box 7	0.014
ACVR2B	activin A receptor, type IIB	0.014
CCR6	chemokine (C-C motif) receptor 6	0.013	Human
CD160	CD160 molecule	0.013
DPP4	dipeptidyl-peptidase 4	0.013
CCR1	chemokine (C-C motif) receptor 1	0.013	Human
CD74	CD74 molecule, major histocompatibility complex, class II invariant chain	0.012
CD48	CD48 molecule	0.012
ITGA5	integrin, alpha 5 (fibronectin receptor, alpha polypeptide)	0.012
SLAMF1	signaling lymphocytic activation molecule family member 1	0.011
DKK1	dickkopf homolog 1 (Xenopus laevis)	0.011
CD80	CD80 molecule	0.011
RXRA	retinoid X receptor, alpha	0.011
CXCR2	chemokine (C-X-C motif) receptor 2	0.011	Human
SELE	selectin E	0.011
TNFSF8	tumor necrosis factor (ligand) superfamily, member 8	0.011
HELZ	helicase with zinc finger	0.011
MAPK8	mitogen-activated protein kinase 8	0.011
AMMECR1	Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1	0.011
AXIN1	axin 1	0.011
IL7R	interleukin 7 receptor	0.010
IL1A	interleukin 1, alpha	0.010
IL18RAP	interleukin 18 receptor accessory protein	0.010
CCR9	chemokine (C-C motif) receptor 9	0.010	Human
GPR18	G protein-coupled receptor 18	0.010
TFPI2	tissue factor pathway inhibitor 2	0.010
CXCR5	chemokine (C-X-C motif) receptor 5	0.010	Human