IMP

Process View

Homo sapiens

10 genes annotated in human

Multi-species View

bone morphogenesis

GO:0060349

The process in which bones are generated and organized.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "bone morphogenesis"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "bone morphogenesis" (in gray)

Name	Description	Probability	Func Analog Organism
TGFBR2	transforming growth factor, beta receptor II (70/80kDa)	0.739	Mouse
POU5F1	POU class 5 homeobox 1	0.522
FGF1	fibroblast growth factor 1 (acidic)	0.158
MMP2	matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)	0.115
FSTL1	follistatin-like 1	0.114
TGFB1	transforming growth factor, beta 1	0.103	Rat
TGFB3	transforming growth factor, beta 3	0.103	Rat
DAB2	disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)	0.101
AMMECR1	Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1	0.099
ENG	endoglin	0.095
PDGFRA	platelet-derived growth factor receptor, alpha polypeptide	0.085
MED25	mediator complex subunit 25	0.080
FN1	fibronectin 1	0.078
PDGFB	platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog)	0.078
SHC1	SHC (Src homology 2 domain containing) transforming protein 1	0.071
APP	amyloid beta (A4) precursor protein	0.059
FLT1	fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)	0.059
VEGFA	vascular endothelial growth factor A	0.057
FGFR1	fibroblast growth factor receptor 1	0.054
EP300	E1A binding protein p300	0.050
SETD8	SET domain containing (lysine methyltransferase) 8	0.049
NOTCH1	notch 1	0.046
PTPN1	protein tyrosine phosphatase, non-receptor type 1	0.041
FGF7	fibroblast growth factor 7	0.039
NOTCH3	notch 3	0.036
POU3F2	POU class 3 homeobox 2	0.036
TGM2	transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase)	0.034
MMP14	matrix metallopeptidase 14 (membrane-inserted)	0.034	Mouse
ANGPT2	angiopoietin 2	0.031
BCAR1	breast cancer anti-estrogen resistance 1	0.026
APBB1	amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)	0.026
THBS1	thrombospondin 1	0.024	Mouse
MSX1	msh homeobox 1	0.022	Mouse
MSX2	msh homeobox 2	0.022	Mouse
COL6A1	collagen, type VI, alpha 1	0.022
MEOX1	mesenchyme homeobox 1	0.021
TFAP2A	transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)	0.021	Mouse
TGFBR1	transforming growth factor, beta receptor 1	0.021
CDH5	cadherin 5, type 2 (vascular endothelium)	0.020
CYP51A1	cytochrome P450, family 51, subfamily A, polypeptide 1	0.020
ITGA5	integrin, alpha 5 (fibronectin receptor, alpha polypeptide)	0.020
FGF10	fibroblast growth factor 10	0.019
MMP12	matrix metallopeptidase 12 (macrophage elastase)	0.019
ANGPT1	angiopoietin 1	0.018
ESR1	estrogen receptor 1	0.018
IDI1	isopentenyl-diphosphate delta isomerase 1	0.017
ARHGEF40	Rho guanine nucleotide exchange factor (GEF) 40	0.017
PTPN12	protein tyrosine phosphatase, non-receptor type 12	0.017
HMGCS1	3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)	0.017
PTHLH	parathyroid hormone-like hormone	0.017
NRP2	neuropilin 2	0.017
MMP3	matrix metallopeptidase 3 (stromelysin 1, progelatinase)	0.017	Human
TCF3	transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47)	0.016
ITGB3	integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)	0.016
CRK	v-crk sarcoma virus CT10 oncogene homolog (avian)	0.016
PDGFRB	platelet-derived growth factor receptor, beta polypeptide	0.016
SMAD7	SMAD family member 7	0.015
SMARCC2	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2	0.015
HMGCR	3-hydroxy-3-methylglutaryl-CoA reductase	0.015
RXRA	retinoid X receptor, alpha	0.015
GLRX	glutaredoxin (thioltransferase)	0.015
STC1	stanniocalcin 1	0.014
NCOA1	nuclear receptor coactivator 1	0.014
MMP1	matrix metallopeptidase 1 (interstitial collagenase)	0.013	Human
TIMP2	TIMP metallopeptidase inhibitor 2	0.013
COL1A1	collagen, type I, alpha 1	0.013	Mouse
MMP10	matrix metallopeptidase 10 (stromelysin 2)	0.013	Human
IGFBP3	insulin-like growth factor binding protein 3	0.013
HIPK2	homeodomain interacting protein kinase 2	0.013
IGFBP5	insulin-like growth factor binding protein 5	0.013
INHBA	inhibin, beta A	0.012
DKK1	dickkopf homolog 1 (Xenopus laevis)	0.012
LRRK2	leucine-rich repeat kinase 2	0.012
SC4MOL	sterol-C4-methyl oxidase-like	0.012
CTGF	connective tissue growth factor	0.011
NRP1	neuropilin 1	0.011
COL1A2	collagen, type I, alpha 2	0.011
CITED2	Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2	0.011	Mouse
PGRMC1	progesterone receptor membrane component 1	0.011
COL5A1	collagen, type V, alpha 1	0.010
SREBF2	sterol regulatory element binding transcription factor 2	0.010
NFIX	nuclear factor I/X (CCAAT-binding transcription factor)	0.010
SMAD4	SMAD family member 4	0.010