IMP

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Homo sapiens

21 genes annotated in human

Multi-species View

regulation of adherens junction organization

GO:1903391

Any process that modulates the frequency, rate or extent of adherens junction organization.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "regulation of adherens junction organization"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "regulation of adherens junction organization" (in gray)

Name	Description	Probability	Func Analog Organism
FLT1	fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)	1.000	Human
PDGFRA	platelet-derived growth factor receptor, alpha polypeptide	0.999	Human
PTK2	PTK2 protein tyrosine kinase 2	0.995
VEGFA	vascular endothelial growth factor A	0.987
S100A9	S100 calcium binding protein A9	0.979	Human
KDR	kinase insert domain receptor (a type III receptor tyrosine kinase)	0.973
S100A6	S100 calcium binding protein A6	0.970	Human
S100A8	S100 calcium binding protein A8	0.963	Human
NRP1	neuropilin 1	0.961
TGFBR2	transforming growth factor, beta receptor II (70/80kDa)	0.945	Human
BCAR1	breast cancer anti-estrogen resistance 1	0.939
FKBP1A	FK506 binding protein 1A, 12kDa	0.917
PDGFRB	platelet-derived growth factor receptor, beta polypeptide	0.860	Human
MLLT4	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4	0.766
BMP2	bone morphogenetic protein 2	0.683
S100A4	S100 calcium binding protein A4	0.670	Human
SMAD7	SMAD family member 7	0.570
CRK	v-crk sarcoma virus CT10 oncogene homolog (avian)	0.566
NCK2	NCK adaptor protein 2	0.564
PTPRB	protein tyrosine phosphatase, receptor type, B	0.513	Human
NCF2	neutrophil cytosolic factor 2	0.485
EFNA1	ephrin-A1	0.469	Human
PDGFB	platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog)	0.467	Human
CDH5	cadherin 5, type 2 (vascular endothelium)	0.419
LIMS1	LIM and senescent cell antigen-like domains 1	0.400
FYN	FYN oncogene related to SRC, FGR, YES	0.366
BMPR2	bone morphogenetic protein receptor, type II (serine/threonine kinase)	0.363	Human
PGF	placental growth factor	0.362	Human
LPXN	leupaxin	0.355	Human
PDGFA	platelet-derived growth factor alpha polypeptide	0.352	Human
EPHA2	EPH receptor A2	0.326	Human
SMAD2	SMAD family member 2	0.300
TEK	TEK tyrosine kinase, endothelial	0.268
EFNA5	ephrin-A5	0.268
AREG	amphiregulin	0.234
MET	met proto-oncogene (hepatocyte growth factor receptor)	0.218
FAF1	Fas (TNFRSF6) associated factor 1	0.216
S100B	S100 calcium binding protein B	0.213	Human
GHR	growth hormone receptor	0.210
ANGPT1	angiopoietin 1	0.209
GDF5	growth differentiation factor 5	0.179
S100A10	S100 calcium binding protein A10	0.174
PTPN23	protein tyrosine phosphatase, non-receptor type 23	0.173
ACVR1	activin A receptor, type I	0.158	Human
CAPG	capping protein (actin filament), gelsolin-like	0.158
PLCG1	phospholipase C, gamma 1	0.156
S100A11	S100 calcium binding protein A11	0.152	Human
TSG101	tumor susceptibility gene 101	0.151
PDGFC	platelet derived growth factor C	0.149
TRIP6	thyroid hormone receptor interactor 6	0.146
MDM2	Mdm2 p53 binding protein homolog (mouse)	0.143
ITGA5	integrin, alpha 5 (fibronectin receptor, alpha polypeptide)	0.141
TGFB3	transforming growth factor, beta 3	0.140
ARHGDIB	Rho GDP dissociation inhibitor (GDI) beta	0.132
ZNF746	zinc finger protein 746	0.128
TGFB1	transforming growth factor, beta 1	0.128
S100A1	S100 calcium binding protein A1	0.123	Human
CRKL	v-crk sarcoma virus CT10 oncogene homolog (avian)-like	0.121
TSC2	tuberous sclerosis 2	0.113
PAG1	phosphoprotein associated with glycosphingolipid microdomains 1	0.112
CDC42EP3	CDC42 effector protein (Rho GTPase binding) 3	0.108
PRKG1	protein kinase, cGMP-dependent, type I	0.097
RRAS	related RAS viral (r-ras) oncogene homolog	0.097
PVRL2	poliovirus receptor-related 2 (herpesvirus entry mediator B)	0.095
ILK	integrin-linked kinase	0.094
CHMP4B	chromatin modifying protein 4B	0.090
ZYX	zyxin	0.088
ENG	endoglin	0.088
HOXA1	homeobox A1	0.082
FHL2	four and a half LIM domains 2	0.079
RHOA	ras homolog gene family, member A	0.075
EPHA7	EPH receptor A7	0.075	Human
KITLG	KIT ligand	0.072
CDC42	cell division cycle 42 (GTP binding protein, 25kDa)	0.071	Human
S100P	S100 calcium binding protein P	0.070	Human
GAB1	GRB2-associated binding protein 1	0.069
MAGI3	membrane associated guanylate kinase, WW and PDZ domain containing 3	0.065
TGFBR1	transforming growth factor, beta receptor 1	0.064	Human
RAC1	ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)	0.060
DPYSL4	dihydropyrimidinase-like 4	0.060
EMP3	epithelial membrane protein 3	0.056
S100A12	S100 calcium binding protein A12	0.054	Human
CTNND1	catenin (cadherin-associated protein), delta 1	0.050
ANGPT2	angiopoietin 2	0.048
AGER	advanced glycosylation end product-specific receptor	0.047
ITGA7	integrin, alpha 7	0.045
FSTL1	follistatin-like 1	0.045
SOS1	son of sevenless homolog 1 (Drosophila)	0.044
PHC2	polyhomeotic homolog 2 (Drosophila)	0.043
EFNB2	ephrin-B2	0.042	Human
PLP2	proteolipid protein 2 (colonic epithelium-enriched)	0.041
RHOC	ras homolog gene family, member C	0.039
FURIN	furin (paired basic amino acid cleaving enzyme)	0.039
TIE1	tyrosine kinase with immunoglobulin-like and EGF-like domains 1	0.038	Human
BMP4	bone morphogenetic protein 4	0.036
LRSAM1	leucine rich repeat and sterile alpha motif containing 1	0.035
PHF21A	PHD finger protein 21A	0.035
LIMK1	LIM domain kinase 1	0.035
MAP3K11	mitogen-activated protein kinase kinase kinase 11	0.035
ERBB2	v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)	0.034
CDC42EP1	CDC42 effector protein (Rho GTPase binding) 1	0.034
LGALS3	lectin, galactoside-binding, soluble, 3	0.034
S100A2	S100 calcium binding protein A2	0.034	Human
ITGA3	integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)	0.033
ARHGDIA	Rho GDP dissociation inhibitor (GDI) alpha	0.033
NEDD4L	neural precursor cell expressed, developmentally down-regulated 4-like	0.033
SORBS3	sorbin and SH3 domain containing 3	0.032
COL6A1	collagen, type VI, alpha 1	0.030
EGFR	epidermal growth factor receptor	0.030
LDLR	low density lipoprotein receptor	0.029
RAC3	ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)	0.029
TMSB10	thymosin beta 10	0.029
PTPRJ	protein tyrosine phosphatase, receptor type, J	0.028
SHC1	SHC (Src homology 2 domain containing) transforming protein 1	0.027
EZR	ezrin	0.024
MMP2	matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)	0.023
SH3BGRL3	SH3 domain binding glutamic acid-rich protein like 3	0.022
UBE2R2	ubiquitin-conjugating enzyme E2R 2	0.022
EPHA3	EPH receptor A3	0.022
MDFI	MyoD family inhibitor	0.022
PPBP	pro-platelet basic protein (chemokine (C-X-C motif) ligand 7)	0.021
MMP16	matrix metallopeptidase 16 (membrane-inserted)	0.021
CDKN2A	cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4)	0.021
RAMP2	receptor (G protein-coupled) activity modifying protein 2	0.020
PDLIM4	PDZ and LIM domain 4	0.020
MAPKAPK2	mitogen-activated protein kinase-activated protein kinase 2	0.020
ERG	v-ets erythroblastosis virus E26 oncogene homolog (avian)	0.019
LMNA	lamin A/C	0.019
SHB	Src homology 2 domain containing adaptor protein B	0.018
RXRA	retinoid X receptor, alpha	0.018
SEMA3F	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F	0.017
LGALS1	lectin, galactoside-binding, soluble, 1	0.017
DIAPH1	diaphanous homolog 1 (Drosophila)	0.017
DOCK1	dedicator of cytokinesis 1	0.017
CD63	CD63 molecule	0.017
SLPI	secretory leukocyte peptidase inhibitor	0.016
TNFRSF12A	tumor necrosis factor receptor superfamily, member 12A	0.016
GRB7	growth factor receptor-bound protein 7	0.016
RHOU	ras homolog gene family, member U	0.016
ANXA2	annexin A2	0.016
CSTA	cystatin A (stefin A)	0.016
MAPK8	mitogen-activated protein kinase 8	0.016
NRP2	neuropilin 2	0.016
CD34	CD34 molecule	0.015
RAPGEF1	Rap guanine nucleotide exchange factor (GEF) 1	0.015
FLT4	fms-related tyrosine kinase 4	0.015	Human
ROBO4	roundabout homolog 4, magic roundabout (Drosophila)	0.015
FGFR1	fibroblast growth factor receptor 1	0.015
CAV1	caveolin 1, caveolae protein, 22kDa	0.015
JUP	junction plakoglobin	0.015
EMCN	endomucin	0.015
ZNF426	zinc finger protein 426	0.014
SMAD6	SMAD family member 6	0.014
POM121	POM121 membrane glycoprotein	0.014
IGFBP5	insulin-like growth factor binding protein 5	0.014
WNT2	wingless-type MMTV integration site family member 2	0.014
ANTXR2	anthrax toxin receptor 2	0.014
BTRC	beta-transducin repeat containing	0.014
SYDE1	synapse defective 1, Rho GTPase, homolog 1 (C. elegans)	0.013
TIMP2	TIMP metallopeptidase inhibitor 2	0.013
TGFB2	transforming growth factor, beta 2	0.013
JAG1	jagged 1	0.013
EPHB3	EPH receptor B3	0.013	Human
KIAA1033	KIAA1033	0.013
PSG5	pregnancy specific beta-1-glycoprotein 5	0.013
FES	feline sarcoma oncogene	0.013
VAT1	vesicle amine transport protein 1 homolog (T. californica)	0.013
ACVR1B	activin A receptor, type IB	0.013	Human
CFTR	cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)	0.012
SLC9A3R1	solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1	0.012
COTL1	coactosin-like 1 (Dictyostelium)	0.012
PXN	paxillin	0.012	Human
MMP19	matrix metallopeptidase 19	0.012
PARVA	parvin, alpha	0.012
SLC9A3R2	solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2	0.012
ZFYVE9	zinc finger, FYVE domain containing 9	0.012
GIT2	G protein-coupled receptor kinase interacting ArfGAP 2	0.012
PLXND1	plexin D1	0.012
EFHD2	EF-hand domain family, member D2	0.012
CSTB	cystatin B (stefin B)	0.012
SOX7	SRY (sex determining region Y)-box 7	0.011
TAGLN2	transgelin 2	0.011
CD97	CD97 molecule	0.011
RAC2	ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)	0.011	Human
LUM	lumican	0.011
IQGAP1	IQ motif containing GTPase activating protein 1	0.011
WAS	Wiskott-Aldrich syndrome (eczema-thrombocytopenia)	0.011
ITGA8	integrin, alpha 8	0.011
S100A16	S100 calcium binding protein A16	0.011
IL1R2	interleukin 1 receptor, type II	0.011
PAWR	PRKC, apoptosis, WT1, regulator	0.011
LMO2	LIM domain only 2 (rhombotin-like 1)	0.011
DDR1	discoidin domain receptor tyrosine kinase 1	0.011
BMPR1A	bone morphogenetic protein receptor, type IA	0.011	Human
ELF4	E74-like factor 4 (ets domain transcription factor)	0.011
GIPC1	GIPC PDZ domain containing family, member 1	0.011
PDE2A	phosphodiesterase 2A, cGMP-stimulated	0.010
SMURF1	SMAD specific E3 ubiquitin protein ligase 1	0.010
CXXC5	CXXC finger protein 5	0.010
TIMP1	TIMP metallopeptidase inhibitor 1	0.010
IGSF21	immunoglobin superfamily, member 21	0.010
NAGK	N-acetylglucosamine kinase	0.010
PARVB	parvin, beta	0.010
SLC16A3	solute carrier family 16, member 3 (monocarboxylic acid transporter 4)	0.010
AHNAK	AHNAK nucleoprotein	0.010
PI3	peptidase inhibitor 3, skin-derived	0.010