Mus musculus

0 known processes

Klra2

killer cell lectin-like receptor, subfamily A, member 2

(Aliases: Klra30,Ly49b)

Klra2 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
detection of fungus GO:0016046 2 0.997
Mouse
cell surface pattern recognition receptor signaling pathway GO:0002752 2 0.982
Mouse
defense response to bacterium GO:0042742 119 0.926
Mouse
defense response to other organism GO:0098542 197 0.912
Mouse
regulation of innate immune response GO:0045088 91 0.878
Mouse
stimulatory c type lectin receptor signaling pathway GO:0002223 2 0.878
Mouse
defense response to gram positive bacterium GO:0050830 50 0.815
Mouse
detection of yeast GO:0001879 2 0.769
Mouse
response to molecule of bacterial origin GO:0002237 143 0.718
Mouse
detection of other organism GO:0098543 8 0.691
Mouse
innate immune response activating cell surface receptor signaling pathway GO:0002220 4 0.682
Mouse
keratinocyte migration GO:0051546 3 0.624
innate immune response GO:0045087 157 0.599
Mouse
cellular response to lipopolysaccharide GO:0071222 77 0.549
Mouse
response to molecule of fungal origin GO:0002238 4 0.531
Mouse
positive regulation of defense response GO:0031349 124 0.515
Mouse
detection of biotic stimulus GO:0009595 10 0.479
Mouse
activation of innate immune response GO:0002218 56 0.473
Mouse
immune effector process GO:0002252 321 0.405
Mouse
regulation of defense response GO:0031347 233 0.402
Mouse
cellular response to molecule of fungal origin GO:0071226 2 0.401
Mouse
immune response regulating signaling pathway GO:0002764 125 0.384
Mouse
cytokine production GO:0001816 319 0.343
Mouse
immune response activating cell surface receptor signaling pathway GO:0002429 72 0.329
Mouse
positive regulation of innate immune response GO:0045089 80 0.300
Mouse
positive regulation of cytokine production GO:0001819 174 0.294
Mouse
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.291
positive regulation by symbiont of defense related host nitric oxide production GO:0052347 1 0.285
positive regulation of phagocytosis GO:0050766 26 0.284
Mouse
neutrophil chemotaxis GO:0030593 36 0.280
cellular response to biotic stimulus GO:0071216 92 0.278
Mouse
leukocyte proliferation GO:0070661 172 0.266
immune response regulating cell surface receptor signaling pathway GO:0002768 80 0.260
Mouse
regulation of inflammatory response GO:0050727 147 0.260
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.258
reactive oxygen species metabolic process GO:0072593 84 0.247
helper t cell chemotaxis GO:0035704 1 0.243
leukocyte activation involved in immune response GO:0002366 126 0.243
Mouse
cell activation involved in immune response GO:0002263 126 0.239
Mouse
tumor necrosis factor production GO:0032640 50 0.239
Mouse
chemotaxis GO:0006935 247 0.238
regulation of tumor necrosis factor superfamily cytokine production GO:1903555 50 0.225
Mouse
regulation of cytokine biosynthetic process GO:0042035 59 0.216
regulation of lymphocyte activation GO:0051249 240 0.213
regulation of chemokine production GO:0032642 30 0.206
membrane organization GO:0061024 245 0.199
Mouse
detection of external biotic stimulus GO:0098581 9 0.195
Mouse
neutrophil migration GO:1990266 37 0.192
reactive oxygen species biosynthetic process GO:1903409 8 0.192
cell killing GO:0001906 67 0.191
Mouse
cation transport GO:0006812 399 0.189
nitrogen compound transport GO:0071705 271 0.184
innate immune response activating signal transduction GO:0002758 50 0.182
Mouse
leukocyte migration GO:0050900 124 0.176
leukocyte mediated immunity GO:0002443 174 0.173
Mouse
regulation of exocytosis GO:0017157 61 0.172
regulation of cytokine production GO:0001817 266 0.168
Mouse
peptide transport GO:0015833 133 0.165
regulation of cell activation GO:0050865 289 0.165
cell chemotaxis GO:0060326 81 0.161
cytokine metabolic process GO:0042107 71 0.153
cellular response to cytokine stimulus GO:0071345 189 0.149
myeloid leukocyte mediated immunity GO:0002444 42 0.149
regulation of leukocyte mediated immunity GO:0002703 104 0.147
Mouse
regulation of lymphocyte proliferation GO:0050670 117 0.141
immune response activating signal transduction GO:0002757 116 0.137
Mouse
positive regulation of tumor necrosis factor biosynthetic process GO:0042535 8 0.135
regulation of secretion GO:0051046 274 0.130
regulation of interleukin 6 production GO:0032675 55 0.129
symbiosis encompassing mutualism through parasitism GO:0044403 83 0.129
positive regulation of macrophage chemotaxis GO:0010759 5 0.129
cellular response to peptidoglycan GO:0071224 4 0.125
regulation of vesicle mediated transport GO:0060627 139 0.119
Mouse
i kappab kinase nf kappab signaling GO:0007249 85 0.119
regulation of reactive oxygen species metabolic process GO:2000377 40 0.117
mast cell activation GO:0045576 27 0.115
positive regulation of cytokine biosynthetic process GO:0042108 40 0.114
leukocyte chemotaxis GO:0030595 69 0.114
detection of bacterium GO:0016045 7 0.114
regulation of defense response to bacterium GO:1900424 3 0.114
regulation of phagocytosis GO:0050764 33 0.112
Mouse
lymphocyte mediated immunity GO:0002449 139 0.111
Mouse
cytokine secretion GO:0050663 72 0.110
cellular response to molecule of bacterial origin GO:0071219 83 0.107
Mouse
natural killer cell mediated cytotoxicity GO:0042267 29 0.107
Mouse
endocytosis GO:0006897 168 0.107
Mouse
positive regulation of natural killer cell mediated immunity GO:0002717 16 0.106
Mouse
interleukin 18 production GO:0032621 4 0.104
pattern recognition receptor signaling pathway GO:0002221 47 0.103
Mouse
tumor necrosis factor biosynthetic process GO:0042533 10 0.103
positive regulation of interferon gamma production GO:0032729 39 0.101
Mouse
negative regulation of cytokine production GO:0001818 84 0.100
regulation of interferon gamma production GO:0032649 57 0.098
Mouse
inflammatory response GO:0006954 244 0.096
cytokine biosynthetic process GO:0042089 68 0.096
mast cell activation involved in immune response GO:0002279 20 0.096
positive regulation of t cell receptor signaling pathway GO:0050862 4 0.093
regulation of mast cell activation GO:0033003 21 0.093
positive regulation of immune effector process GO:0002699 107 0.092
Mouse
positive regulation of cell activation GO:0050867 158 0.092
regulation of establishment of protein localization GO:0070201 181 0.090
second messenger mediated signaling GO:0019932 73 0.087
t helper 17 cell chemotaxis GO:0035705 1 0.086
negative regulation of mast cell degranulation GO:0043305 4 0.086
positive regulation of toll like receptor 9 signaling pathway GO:0034165 2 0.084
lymphocyte proliferation GO:0046651 164 0.084
chemokine production GO:0032602 34 0.083
negative regulation of cellular protein metabolic process GO:0032269 247 0.083
positive regulation of immunological synapse formation GO:2000522 1 0.083
interferon gamma production GO:0032609 67 0.081
Mouse
granulocyte migration GO:0097530 43 0.081
regulation of leukocyte mediated cytotoxicity GO:0001910 38 0.079
Mouse
negative regulation of immune system process GO:0002683 209 0.079
regulation of vascular endothelial growth factor production GO:0010574 13 0.078
cell recognition GO:0008037 83 0.077
Mouse
regulation of intracellular transport GO:0032386 159 0.077
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.077
myeloid leukocyte differentiation GO:0002573 119 0.075
regulation of ion homeostasis GO:2000021 64 0.074
humoral immune response GO:0006959 57 0.073
positive regulation of lymphocyte mediated immunity GO:0002708 62 0.072
Mouse
regulation of response to wounding GO:1903034 189 0.071
mapk cascade GO:0000165 281 0.070
regulation of neutrophil chemotaxis GO:0090022 14 0.070
natural killer cell activation GO:0030101 44 0.070
Mouse
positive regulation of interleukin 18 production GO:0032741 2 0.070
neutrophil mediated killing of gram negative bacterium GO:0070945 4 0.069
activation of immune response GO:0002253 138 0.068
Mouse
divalent inorganic cation transport GO:0072511 178 0.068
cellular homeostasis GO:0019725 240 0.068
positive regulation of monocyte chemotaxis GO:0090026 2 0.067
response to peptidoglycan GO:0032494 9 0.067
positive regulation of leukocyte mediated cytotoxicity GO:0001912 31 0.067
Mouse
myeloid cell differentiation GO:0030099 233 0.066
Mouse
interleukin 6 production GO:0032635 58 0.066
protein kinase b signaling GO:0043491 74 0.066
regulation of leukocyte proliferation GO:0070663 121 0.065
t cell proliferation GO:0042098 120 0.064
aromatic compound catabolic process GO:0019439 286 0.064
response to lipopolysaccharide GO:0032496 128 0.064
Mouse
regulation of cell killing GO:0031341 40 0.063
Mouse
cellular response to lipid GO:0071396 145 0.063
Mouse
positive regulation of leukocyte mediated immunity GO:0002705 70 0.063
Mouse
response to organonitrogen compound GO:0010243 246 0.062
phagocytosis recognition GO:0006910 12 0.060
Mouse
negative regulation of leukocyte mediated immunity GO:0002704 29 0.059
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.058
g protein coupled receptor signaling pathway GO:0007186 243 0.058
regulation of monocyte chemotaxis GO:0090025 3 0.057
disruption by host of symbiont cells GO:0051852 11 0.057
positive regulation of protein transport GO:0051222 93 0.057
regulation of protein localization GO:0032880 231 0.057
reactive nitrogen species metabolic process GO:2001057 0 0.056
maintenance of location GO:0051235 89 0.056
toll like receptor signaling pathway GO:0002224 38 0.056
regulation of cell migration GO:0030334 219 0.056
organic acid transport GO:0015849 101 0.055
regulation of multi organism process GO:0043900 111 0.055
leukocyte mediated cytotoxicity GO:0001909 62 0.054
Mouse
monocyte chemotactic protein 1 production GO:0071605 1 0.054
adaptive immune response GO:0002250 155 0.053
granulocyte chemotaxis GO:0071621 39 0.053
cellular response to drug GO:0035690 15 0.053
Mouse
positive regulation of interferon alpha biosynthetic process GO:0045356 1 0.052
calcium mediated signaling GO:0019722 46 0.052
leukocyte degranulation GO:0043299 27 0.052
regulation of cellular response to stress GO:0080135 159 0.051
killing of cells in other organism involved in symbiotic interaction GO:0051883 13 0.051
nitric oxide biosynthetic process GO:0006809 25 0.051
Mouse
mast cell mediated immunity GO:0002448 20 0.050
positive regulation of lymphocyte proliferation GO:0050671 70 0.050
regulation of endocytosis GO:0030100 69 0.050
Mouse
positive regulation of tumor necrosis factor production GO:0032760 30 0.049
Mouse
regulation of chemotaxis GO:0050920 53 0.049
cellular nitrogen compound catabolic process GO:0044270 280 0.048
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 55 0.048
natural killer cell mediated immunity GO:0002228 29 0.048
Mouse
signal transduction in absence of ligand GO:0038034 55 0.048
cellular response to organonitrogen compound GO:0071417 145 0.048
positive regulation of endocytosis GO:0045807 42 0.048
Mouse
positive regulation of response to wounding GO:1903036 66 0.048
defense response to virus GO:0051607 68 0.048
multicellular organismal signaling GO:0035637 91 0.047
urogenital system development GO:0001655 261 0.047
negative regulation of homeostatic process GO:0032845 71 0.047
interferon beta biosynthetic process GO:0045350 4 0.047
cytokine mediated signaling pathway GO:0019221 115 0.047
cellular ketone metabolic process GO:0042180 84 0.047
disruption of cells of other organism involved in symbiotic interaction GO:0051818 13 0.046
adenylate cyclase modulating g protein coupled receptor signaling pathway GO:0007188 54 0.046
exocytosis GO:0006887 121 0.046
t cell activation GO:0042110 289 0.046
negative regulation of cell proliferation GO:0008285 296 0.046
lysosome localization GO:0032418 20 0.046
positive regulation of t cell extravasation GO:2000409 2 0.046
defense response to gram negative bacterium GO:0050829 28 0.045
positive regulation of lymphocyte activation GO:0051251 140 0.045
neutrophil mediated killing of bacterium GO:0070944 6 0.045
cellular amino acid metabolic process GO:0006520 103 0.044
positive regulation of chemokine biosynthetic process GO:0045080 6 0.044
kidney development GO:0001822 213 0.044
regulation of cellular ketone metabolic process GO:0010565 66 0.044
negative regulation of defense response GO:0031348 77 0.044
fat cell differentiation GO:0045444 160 0.043
positive regulation of cytokine secretion GO:0050715 41 0.043
antibacterial peptide biosynthetic process GO:0002780 2 0.043
positive regulation of chemokine production GO:0032722 22 0.043
stress activated mapk cascade GO:0051403 80 0.043
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 87 0.042
negative regulation of phagocytosis GO:0050765 4 0.042
positive regulation of cellular amine metabolic process GO:0033240 5 0.042
positive regulation of neutrophil mediated killing of symbiont cell GO:0070961 1 0.042
phagocytosis GO:0006909 66 0.042
Mouse
negative regulation of protein metabolic process GO:0051248 282 0.041
production of molecular mediator involved in inflammatory response GO:0002532 21 0.041
alpha beta t cell activation GO:0046631 91 0.041
cation homeostasis GO:0055080 212 0.041
positive regulation of secretion by cell GO:1903532 114 0.041
regulation of humoral immune response GO:0002920 22 0.041
regulation of t cell costimulation GO:2000523 2 0.040
cellular chemical homeostasis GO:0055082 215 0.040
negative regulation of interferon gamma production GO:0032689 18 0.040
toll like receptor 7 signaling pathway GO:0034154 4 0.040
positive regulation of cytoplasmic transport GO:1903651 40 0.039
toxin catabolic process GO:0009407 1 0.039
anion transport GO:0006820 177 0.039
negative regulation of adaptive immune response GO:0002820 25 0.038
response to organic cyclic compound GO:0014070 198 0.038
modulation by organism of defense response of other organism involved in symbiotic interaction GO:0052255 1 0.038
positive regulation of t cell costimulation GO:2000525 2 0.038
regulation of t cell proliferation GO:0042129 92 0.038
macrophage chemotaxis GO:0048246 14 0.037
cytosolic calcium ion transport GO:0060401 48 0.037
regulation of apoptotic signaling pathway GO:2001233 197 0.037
positive regulation of glycoprotein biosynthetic process involved in immunological synapse formation GO:2000526 1 0.037
neutrophil mediated killing of gram positive bacterium GO:0070946 2 0.037
positive regulation of stress activated mapk cascade GO:0032874 48 0.036
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.036
ion transmembrane transport GO:0034220 361 0.036
positive regulation of t cell activation GO:0050870 101 0.036
antibacterial peptide production GO:0002778 2 0.036
carbohydrate derivative biosynthetic process GO:1901137 183 0.036
divalent metal ion transport GO:0070838 172 0.036
blood vessel morphogenesis GO:0048514 285 0.035
regulation of cellular catabolic process GO:0031329 242 0.035
positive regulation of b cell activation GO:0050871 49 0.035
positive regulation of jnk cascade GO:0046330 46 0.035
regulation of jnk cascade GO:0046328 62 0.035
purine nucleoside triphosphate metabolic process GO:0009144 226 0.035
regulation of secretion by cell GO:1903530 249 0.035
regulation of natural killer cell mediated immunity GO:0002715 19 0.035
Mouse
regulation of toll like receptor 9 signaling pathway GO:0034163 3 0.035
microglial cell activation GO:0001774 3 0.034
sequestering of metal ion GO:0051238 19 0.034
positive regulation of nitric oxide biosynthetic process GO:0045429 14 0.034
Mouse
eosinophil activation involved in immune response GO:0002278 1 0.034
sequestering of calcium ion GO:0051208 18 0.034
heterocycle catabolic process GO:0046700 280 0.034
regulation of protein kinase b signaling GO:0051896 56 0.034
negative regulation of eosinophil degranulation GO:0043310 1 0.034
cation transmembrane transport GO:0098655 266 0.033
positive regulation of interleukin 6 production GO:0032755 37 0.033
regulation of hormone levels GO:0010817 211 0.033
regulated secretory pathway GO:0045055 32 0.033
positive regulation of tumor necrosis factor superfamily cytokine production GO:1903557 31 0.033
Mouse
regulation of cell motility GO:2000145 236 0.033
nucleoside phosphate metabolic process GO:0006753 338 0.033
regulation of tumor necrosis factor production GO:0032680 49 0.033
Mouse
single organismal cell cell adhesion GO:0016337 131 0.033
Mouse
regulation of cytokine secretion GO:0050707 61 0.032
inflammatory response to wounding GO:0090594 4 0.032
regulation of protein processing GO:0070613 96 0.032
chemokine metabolic process GO:0050755 10 0.032
organonitrogen compound catabolic process GO:1901565 264 0.032
positive regulation of cell killing GO:0031343 33 0.032
Mouse
leukocyte differentiation GO:0002521 342 0.032
single organism nuclear import GO:1902593 95 0.032
intracellular protein transport GO:0006886 204 0.032
positive regulation of map kinase activity GO:0043406 84 0.032
positive regulation of interferon alpha production GO:0032727 4 0.032
regulation of mapk cascade GO:0043408 248 0.031
regulation of antimicrobial humoral response GO:0002759 3 0.031
protein targeting GO:0006605 143 0.031
regulation of lymphocyte mediated immunity GO:0002706 84 0.031
Mouse
fc epsilon receptor signaling pathway GO:0038095 3 0.031
transmission of nerve impulse GO:0019226 76 0.031
t cell receptor signaling pathway GO:0050852 46 0.031
cytosolic calcium ion homeostasis GO:0051480 70 0.030
sensory perception GO:0007600 245 0.030
regulation of homeostatic process GO:0032844 182 0.030
negative regulation of leukocyte proliferation GO:0070664 46 0.030
positive regulation of chemotaxis GO:0050921 38 0.030
secondary metabolite catabolic process GO:0090487 1 0.030
vascular endothelial growth factor production GO:0010573 13 0.029
regulation of stress activated mapk cascade GO:0032872 69 0.029
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.029
purine ribonucleotide metabolic process GO:0009150 290 0.029
positive regulation of granulocyte chemotaxis GO:0071624 12 0.029
glycoprotein biosynthetic process GO:0009101 89 0.029
defense response to fungus GO:0050832 12 0.028
interspecies interaction between organisms GO:0044419 83 0.028
regulation of ion transport GO:0043269 215 0.028
b cell proliferation GO:0042100 53 0.028
modification of morphology or physiology of other organism involved in symbiotic interaction GO:0051817 16 0.028
negative regulation of inflammatory response to antigenic stimulus GO:0002862 10 0.028
carboxylic acid transport GO:0046942 100 0.028
organelle localization GO:0051640 179 0.028
positive regulation of membrane protein ectodomain proteolysis GO:0051044 3 0.028
oxidation reduction process GO:0055114 342 0.027
positive regulation of cd8 positive alpha beta t cell extravasation GO:2000451 2 0.027
purine ribonucleotide catabolic process GO:0009154 208 0.027
neutrophil mediated immunity GO:0002446 19 0.027
carbohydrate derivative catabolic process GO:1901136 231 0.027
regulation of t cell extravasation GO:2000407 3 0.027
platelet morphogenesis GO:0036344 13 0.027
Mouse
extrinsic apoptotic signaling pathway GO:0097191 126 0.027
cellular response to external stimulus GO:0071496 88 0.027
positive regulation of natural killer cell mediated cytotoxicity GO:0045954 16 0.027
Mouse
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger GO:0007187 55 0.027
negative regulation of serotonin secretion GO:0014063 2 0.027
amide transport GO:0042886 138 0.027
negative regulation of secretion GO:0051048 61 0.027
regulation of membrane potential GO:0042391 192 0.027
ribonucleoside triphosphate catabolic process GO:0009203 199 0.027
regulation of acute inflammatory response GO:0002673 27 0.026
myeloid leukocyte activation GO:0002274 83 0.026
positive regulation of inflammatory response GO:0050729 47 0.026
negative regulation of hypersensitivity GO:0002884 3 0.026
wound healing GO:0042060 157 0.026
regulation of cd8 positive alpha beta t cell extravasation GO:2000449 3 0.026
regulation of neutrophil migration GO:1902622 14 0.026
apoptotic signaling pathway GO:0097190 306 0.026
regulation of protein kinase activity GO:0045859 232 0.026
immunoglobulin transcytosis in epithelial cells GO:0002414 2 0.026
neutrophil mediated cytotoxicity GO:0070942 8 0.026
amine metabolic process GO:0009308 45 0.026
endomembrane system organization GO:0010256 147 0.026
transmembrane transport GO:0055085 412 0.026
negative regulation of t cell proliferation GO:0042130 38 0.026
organic cyclic compound catabolic process GO:1901361 295 0.026
antimicrobial peptide secretion GO:0002776 1 0.026
negative regulation of inflammatory response GO:0050728 61 0.026
calcium ion homeostasis GO:0055074 127 0.025
positive regulation of dendritic cell chemotaxis GO:2000510 1 0.025
microglial cell activation involved in immune response GO:0002282 1 0.025
positive regulation of adaptive immune response GO:0002821 61 0.025
olfactory learning GO:0008355 2 0.025
cytoplasmic transport GO:0016482 234 0.025
regulation of calcium ion transport GO:0051924 69 0.025
nucleotide metabolic process GO:0009117 332 0.025
positive regulation of leukocyte proliferation GO:0070665 73 0.025
phospholipase c activating g protein coupled receptor signaling pathway GO:0007200 26 0.025
tumor necrosis factor superfamily cytokine production GO:0071706 51 0.025
Mouse
rho protein signal transduction GO:0007266 32 0.025
regulation of cellular amine metabolic process GO:0033238 20 0.025
regulation of antigen receptor mediated signaling pathway GO:0050854 29 0.025
myeloid leukocyte migration GO:0097529 57 0.025
interaction with symbiont GO:0051702 14 0.025
amino acid transport GO:0006865 61 0.025
myeloid cell activation involved in immune response GO:0002275 34 0.025
protein maturation GO:0051604 176 0.025
eosinophil degranulation GO:0043308 1 0.024
antimicrobial peptide production GO:0002775 2 0.024
regulation of dendritic cell chemotaxis GO:2000508 1 0.024
stress activated protein kinase signaling cascade GO:0031098 81 0.024
nuclear import GO:0051170 95 0.024
regulation of immunoglobulin mediated immune response GO:0002889 37 0.024
cell adhesion GO:0007155 329 0.024
Mouse
jnk cascade GO:0007254 72 0.024
b cell activation GO:0042113 161 0.024
dna metabolic process GO:0006259 303 0.024
regulation of cytoplasmic transport GO:1903649 112 0.024
purine containing compound metabolic process GO:0072521 311 0.024
negative regulation of phosphorus metabolic process GO:0010563 184 0.023
nuclear transport GO:0051169 139 0.023
purine nucleotide metabolic process GO:0006163 302 0.023
organic anion transport GO:0015711 137 0.023
protein secretion GO:0009306 111 0.023
negative regulation of phosphorylation GO:0042326 166 0.023
cd8 positive alpha beta t cell extravasation GO:0035697 3 0.023
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.023
regulation of t cell activation GO:0050863 170 0.023
glycosyl compound metabolic process GO:1901657 246 0.023
positive regulation of homeostatic process GO:0032846 64 0.023
serotonin secretion involved in inflammatory response GO:0002442 4 0.023
activation of mapk activity GO:0000187 59 0.023
membrane invagination GO:0010324 17 0.023
Mouse
cellular metal ion homeostasis GO:0006875 151 0.023
inorganic ion transmembrane transport GO:0098660 234 0.022
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.022
epithelial tube morphogenesis GO:0060562 303 0.022
organonitrogen compound biosynthetic process GO:1901566 192 0.022
osteoclast differentiation GO:0030316 62 0.022
regulation of mast cell degranulation GO:0043304 16 0.022
regulation of natural killer cell mediated cytotoxicity GO:0042269 19 0.022
Mouse
killing by host of symbiont cells GO:0051873 11 0.022
negative regulation of multi organism process GO:0043901 68 0.022
regulation of myeloid leukocyte mediated immunity GO:0002886 25 0.022
multicellular organismal homeostasis GO:0048871 164 0.022
negative regulation of immune effector process GO:0002698 55 0.022
cellular response to organic cyclic compound GO:0071407 87 0.022
cognition GO:0050890 149 0.022
divalent inorganic cation homeostasis GO:0072507 138 0.022
inorganic cation transmembrane transport GO:0098662 207 0.022
regulation of chemokine secretion GO:0090196 4 0.022
modification of morphology or physiology of other organism GO:0035821 18 0.021
negative regulation of lymphocyte activation GO:0051250 91 0.021
carbohydrate metabolic process GO:0005975 230 0.021
wound healing involved in inflammatory response GO:0002246 4 0.021
nitric oxide metabolic process GO:0046209 25 0.021
Mouse
negative regulation of growth GO:0045926 99 0.021
regulation of inflammatory response to antigenic stimulus GO:0002861 21 0.021
ribose phosphate metabolic process GO:0019693 291 0.021
negative regulation of molecular function GO:0044092 258 0.021
antigen receptor mediated signaling pathway GO:0050851 64 0.021
cellular amine metabolic process GO:0044106 44 0.021
protein import into nucleus GO:0006606 95 0.021
negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 23 0.021
regulation of toll like receptor 2 signaling pathway GO:0034135 3 0.021
response to oxidative stress GO:0006979 123 0.021
regulation of regulated secretory pathway GO:1903305 20 0.021
positive regulation of angiogenesis GO:0045766 46 0.021
negative regulation of lymphocyte proliferation GO:0050672 45 0.021
regulation of hydrolase activity GO:0051336 246 0.020
positive regulation of erk1 and erk2 cascade GO:0070374 47 0.020
cellular response to interleukin 15 GO:0071350 2 0.020
regulation of protein secretion GO:0050708 82 0.020
nucleoside metabolic process GO:0009116 246 0.020
cellular divalent inorganic cation homeostasis GO:0072503 127 0.020
positive regulation of calcium mediated signaling GO:0050850 15 0.020
serotonin secretion by mast cell GO:0002552 1 0.020
antigen processing and presentation GO:0019882 47 0.020
regulation of toll like receptor signaling pathway GO:0034121 20 0.020
regulation of eosinophil degranulation GO:0043309 1 0.020
cellular carbohydrate metabolic process GO:0044262 119 0.020
protein localization to organelle GO:0033365 185 0.020
negative regulation of intracellular signal transduction GO:1902532 167 0.020
erk1 and erk2 cascade GO:0070371 77 0.020
organophosphate catabolic process GO:0046434 232 0.020
purine containing compound catabolic process GO:0072523 213 0.019
sensory perception of pain GO:0019233 47 0.019
positive regulation of intracellular transport GO:0032388 70 0.019
regulation of map kinase activity GO:0043405 120 0.019
positive regulation of transcription from rna polymerase ii promoter involved in smooth muscle cell differentiation GO:2000721 2 0.019
purine nucleoside metabolic process GO:0042278 241 0.019
purine nucleoside catabolic process GO:0006152 205 0.019
neuron projection guidance GO:0097485 141 0.019
positive regulation of antimicrobial humoral response GO:0002760 2 0.019
negative regulation of chemokine production GO:0032682 4 0.019
positive regulation of protein secretion GO:0050714 52 0.019
nucleobase containing small molecule metabolic process GO:0055086 352 0.019
positive regulation of chemokine secretion GO:0090197 4 0.019
cellular response to extracellular stimulus GO:0031668 81 0.019
negative regulation of type i hypersensitivity GO:0001811 1 0.019
response to host GO:0075136 3 0.019
nucleocytoplasmic transport GO:0006913 139 0.019
purine nucleoside triphosphate catabolic process GO:0009146 203 0.019
positive regulation vascular endothelial growth factor production GO:0010575 10 0.019
antimicrobial peptide biosynthetic process GO:0002777 2 0.019
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 52 0.019
peptidyl amino acid modification GO:0018193 336 0.019
tissue homeostasis GO:0001894 115 0.019
regulation of immunological synapse formation GO:2000520 2 0.018
nucleotide catabolic process GO:0009166 217 0.018
regulation of adiponectin secretion GO:0070163 2 0.018
regulation of protein maturation GO:1903317 96 0.018
negative regulation of protein processing GO:0010955 79 0.018
negative regulation of leukocyte degranulation GO:0043301 7 0.018
positive regulation of transferase activity GO:0051347 167 0.018
ossification GO:0001503 216 0.018
positive regulation of secretion GO:0051047 130 0.018
nucleic acid phosphodiester bond hydrolysis GO:0090305 49 0.018
regulation of interleukin 18 production GO:0032661 3 0.018
regulation of b cell activation GO:0050864 81 0.018
positive regulation of interleukin 8 production GO:0032757 2 0.018
negative regulation of interleukin 6 production GO:0032715 17 0.018
positive regulation of antibacterial peptide biosynthetic process GO:0006963 1 0.018
regulation of tumor necrosis factor biosynthetic process GO:0042534 10 0.018
eosinophil activation GO:0043307 1 0.018
response to bacterial lipoprotein GO:0032493 4 0.018
positive regulation of cholesterol storage GO:0010886 3 0.018
regulation of calcium mediated signaling GO:0050848 19 0.018
mitochondrion organization GO:0007005 134 0.018
insulin receptor signaling pathway GO:0008286 49 0.018
cellular ion homeostasis GO:0006873 165 0.017
transforming growth factor beta receptor signaling pathway GO:0007179 71 0.017
negative regulation of proteolysis GO:0045861 74 0.017
organic hydroxy compound transport GO:0015850 93 0.017
receptor mediated endocytosis GO:0006898 51 0.017
Mouse

Klra2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 0 0.078
respiratory system disease DOID:1579 0 0.066
disease of anatomical entity DOID:7 0 0.066
musculoskeletal system disease DOID:17 0 0.063
cancer DOID:162 0 0.055
organ system cancer DOID:0050686 0 0.044
connective tissue disease DOID:65 0 0.036
immune system disease DOID:2914 0 0.024
gastrointestinal system cancer DOID:3119 0 0.021
disease by infectious agent DOID:0050117 0 0.019