IMP

Process View

Mus musculus

3 genes annotated in mouse

fc epsilon receptor signaling pathway

A series of molecular signals initiated by the binding of the Fc portion of immunoglobulin E (IgE) to an Fc-epsilon receptor on the surface of a signal-receiving cell, and ending with regulation of a downstream cellular process, e.g. transcription. The Fc portion of an immunoglobulin is its C-terminal constant region.

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "fc epsilon receptor signaling pathway"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "fc epsilon receptor signaling pathway" (in gray)

Name	Description	Probability	Func Analog Organism
Fcer1g	Fc receptor, IgE, high affinity I, gamma polypeptide	0.997
Il2rg	interleukin 2 receptor, gamma chain	0.972
Ptprc	protein tyrosine phosphatase, receptor type, C	0.925
Tyrobp	TYRO protein tyrosine kinase binding protein	0.862
Rag1	recombination activating gene 1	0.517
Lyz2	lysozyme 2	0.356
Rag2	recombination activating gene 2	0.338
Lat	linker for activation of T cells	0.313
Tcra	T-cell receptor alpha chain	0.311
Ccr1	chemokine (C-C motif) receptor 1	0.298
Clec4n	C-type lectin domain family 4, member n	0.263
Cd247	CD247 antigen	0.230	Mouse
C1qb	complement component 1, q subcomponent, beta polypeptide	0.222
Apoe	apolipoprotein E	0.186
AF251705	cDNA sequence AF251705	0.162
Msr1	macrophage scavenger receptor 1	0.161
Hcst	hematopoietic cell signal transducer	0.152
Lck	lymphocyte protein tyrosine kinase	0.149
Emr1	EGF-like module containing, mucin-like, hormone receptor-like sequence 1	0.130
Fcgr3	Fc receptor, IgG, low affinity III	0.123	Mouse
Ccl6	chemokine (C-C motif) ligand 6	0.102
Ms4a6d	membrane-spanning 4-domains, subfamily A, member 6D	0.088
C3ar1	complement component 3a receptor 1	0.083
Ccl9	chemokine (C-C motif) ligand 9	0.073
Csf1r	colony stimulating factor 1 receptor	0.073
Cd68	CD68 antigen	0.071
Aif1	allograft inflammatory factor 1	0.069
Mpeg1	macrophage expressed gene 1	0.067
Clec4d	C-type lectin domain family 4, member d	0.066
Ikzf1	IKAROS family zinc finger 1	0.065
Slc11a1	solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1	0.063
Lilrb3	leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3	0.062
Csf3r	colony stimulating factor 3 receptor (granulocyte)	0.061
Il7r	interleukin 7 receptor	0.059
C1qc	complement component 1, q subcomponent, C chain	0.058
C1qa	complement component 1, q subcomponent, alpha polypeptide	0.056
C5ar1	complement component 5a receptor 1	0.050
Mmp8	matrix metallopeptidase 8	0.048
Calcrl	calcitonin receptor-like	0.046
Ifitm6	interferon induced transmembrane protein 6	0.045
Sfpi1	SFFV proviral integration 1	0.045
Clec4a2	C-type lectin domain family 4, member a2	0.041
Selp	selectin, platelet	0.041
Fasl	Fas ligand (TNF superfamily, member 6)	0.040
Pik3cg	phosphoinositide-3-kinase, catalytic, gamma polypeptide	0.040
Sell	selectin, lymphocyte	0.040
Cxcr2	chemokine (C-X-C motif) receptor 2	0.039
Clec7a	C-type lectin domain family 7, member a	0.038
Alox5ap	arachidonate 5-lipoxygenase activating protein	0.036
Tlr7	toll-like receptor 7	0.033
Ncf1	neutrophil cytosolic factor 1	0.032
Fpr2	formyl peptide receptor 2	0.032
Lyz1	lysozyme 1	0.031
Tbxas1	thromboxane A synthase 1, platelet	0.031
Pf4	platelet factor 4	0.031
Il1b	interleukin 1 beta	0.031
Ly86	lymphocyte antigen 86	0.031
Klra2	killer cell lectin-like receptor, subfamily A, member 2	0.031
Fpr1	formyl peptide receptor 1	0.031
Inpp5d	inositol polyphosphate-5-phosphatase D	0.030
Btk	Bruton agammaglobulinemia tyrosine kinase	0.030
Mrc1	mannose receptor, C type 1	0.029
Fcgr1	Fc receptor, IgG, high affinity I	0.028	Mouse
Ccr5	chemokine (C-C motif) receptor 5	0.026
Hck	hemopoietic cell kinase	0.025
Ptpn22	protein tyrosine phosphatase, non-receptor type 22 (lymphoid)	0.025
C3	complement component 3	0.025
Csf2rb	colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)	0.024
Cybb	cytochrome b-245, beta polypeptide	0.024
Fcgr2b	Fc receptor, IgG, low affinity IIb	0.023	Mouse
Cd86	CD86 antigen	0.022
P2ry6	pyrimidinergic receptor P2Y, G-protein coupled, 6	0.022
Ms4a6c	membrane-spanning 4-domains, subfamily A, member 6C	0.022
Fcgr4	Fc receptor, IgG, low affinity IV	0.022
Fgr	Gardner-Rasheed feline sarcoma viral (Fgr) oncogene homolog	0.022
B2m	beta-2 microglobulin	0.021
Tlr4	toll-like receptor 4	0.020
Csf2rb2	colony stimulating factor 2 receptor, beta 2, low-affinity (granulocyte-macrophage)	0.020
Cr2	complement receptor 2	0.019
Ccl3	chemokine (C-C motif) ligand 3	0.019
Lair1	leukocyte-associated Ig-like receptor 1	0.019
Zap70	zeta-chain (TCR) associated protein kinase	0.019
Ccl12	chemokine (C-C motif) ligand 12	0.018
Fgd3	FYVE, RhoGEF and PH domain containing 3	0.018
Fas	Fas (TNF receptor superfamily member 6)	0.018
Slpi	secretory leukocyte peptidase inhibitor	0.017
Cd19	CD19 antigen	0.017
Il2	interleukin 2	0.017
Ctss	cathepsin S	0.017
Ncr1	natural cytotoxicity triggering receptor 1	0.017
Folr2	folate receptor 2 (fetal)	0.017
Pilra	paired immunoglobin-like type 2 receptor alpha	0.017
Klrk1	killer cell lectin-like receptor subfamily K, member 1	0.016
Cd180	CD180 antigen	0.016
Lcp2	lymphocyte cytosolic protein 2	0.016
Itgam	integrin alpha M	0.016
Tnf	tumor necrosis factor	0.016
Myo1f	myosin IF	0.016
Adm	adrenomedullin	0.016
Igsf6	immunoglobulin superfamily, member 6	0.016
Chi3l3	chitinase 3-like 3	0.016
Bex6	brain expressed gene 6	0.015
Il18rap	interleukin 18 receptor accessory protein	0.015
Cd96	CD96 antigen	0.015
Cd14	CD14 antigen	0.015
Cd8a	CD8 antigen, alpha chain	0.015
S100a8	S100 calcium binding protein A8 (calgranulin A)	0.015
Cd22	CD22 antigen	0.014
Itgb2	integrin beta 2	0.014
Clec4e	C-type lectin domain family 4, member e	0.014
Pilrb1	paired immunoglobin-like type 2 receptor beta 1	0.014
Il15	interleukin 15	0.013
Aoah	acyloxyacyl hydrolase	0.013
F13a1	coagulation factor XIII, A1 subunit	0.012
Vav1	vav 1 oncogene	0.012
BC013712	cDNA sequence BC013712	0.012
Ifng	interferon gamma	0.012
Pld4	phospholipase D family, member 4	0.012
Trem3	triggering receptor expressed on myeloid cells 3	0.012
Ear2	eosinophil-associated, ribonuclease A family, member 2	0.012
Ncf4	neutrophil cytosolic factor 4	0.012
Clec5a	C-type lectin domain family 5, member a	0.012
Abca1	ATP-binding cassette, sub-family A (ABC1), member 1	0.012
Lilrb4	leukocyte immunoglobulin-like receptor, subfamily B, member 4	0.012
Grap2	GRB2-related adaptor protein 2	0.012
Cfp	complement factor properdin	0.012
Sla	src-like adaptor	0.012
Cd40	CD40 antigen	0.011
Clec4a3	C-type lectin domain family 4, member a3	0.011
Cd300a	CD300A antigen	0.011
Fyn	Fyn proto-oncogene	0.011
Sykb	spleen tyrosine kinase	0.011
Ccr9	chemokine (C-C motif) receptor 9	0.011
Ms4a4c	membrane-spanning 4-domains, subfamily A, member 4C	0.011
Il2rb	interleukin 2 receptor, beta chain	0.011
Gm11428	predicted gene 11428	0.011
Fyb	FYN binding protein	0.011
Klrb1b	killer cell lectin-like receptor subfamily B member 1B	0.011
Itgax	integrin alpha X	0.011
Ccr7	chemokine (C-C motif) receptor 7	0.011
Bmp5	bone morphogenetic protein 5	0.011
Plek	pleckstrin	0.010
Ncf2	neutrophil cytosolic factor 2	0.010
Klrd1	killer cell lectin-like receptor, subfamily D, member 1	0.010
Fcna	ficolin A	0.010
Bst1	bone marrow stromal cell antigen 1	0.010