IMP

Process View

Mus musculus

4 genes annotated in mouse

positive regulation of chemokine secretion

Any process that increases the rate, frequency or extent of chemokine secretion, the regulated release of chemokines from a cell.

Loading network...

In addition to gene-name show these genes:

Known genes in the process in mouse Include functional analogs

Network Filters

Minimum relationship confidence:

Maximum number of genes:

Highlight known relationships in gold.

Graphical Options

Adjust edge length:

Adjust node size:

Fixed layout

Black background

Low confidence color:

Med confidence color:

High confidence color:

Hide the legend in the network

Save Options

Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "positive regulation of chemokine secretion"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "positive regulation of chemokine secretion" (in gray)

Name	Description	Probability	Func Analog Organism
Csf2rb2	colony stimulating factor 2 receptor, beta 2, low-affinity (granulocyte-macrophage)	0.975	Mouse
Csf2rb	colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)	0.925	Mouse
Csf1	colony stimulating factor 1 (macrophage)	0.915
Casp4	caspase 4, apoptosis-related cysteine peptidase	0.771
Il1rl1	interleukin 1 receptor-like 1	0.763
Stat6	signal transducer and activator of transcription 6	0.736
Aim2	absent in melanoma 2	0.451
Il1b	interleukin 1 beta	0.419
Chi3l3	chitinase 3-like 3	0.401	Human
Nlrp3	NLR family, pyrin domain containing 3	0.382
Mmp8	matrix metallopeptidase 8	0.372
S100a9	S100 calcium binding protein A9 (calgranulin B)	0.289
Gbp5	guanylate binding protein 5	0.263
Il1rap	interleukin 1 receptor accessory protein	0.246	Mouse
Il1r2	interleukin 1 receptor, type II	0.240	Mouse
Casp1	caspase 1	0.239
Stat3	signal transducer and activator of transcription 3	0.152
Cxcr2	chemokine (C-X-C motif) receptor 2	0.138
C5ar1	complement component 5a receptor 1	0.128
Il18rap	interleukin 18 receptor accessory protein	0.117	Mouse
Slpi	secretory leukocyte peptidase inhibitor	0.112
Il6	interleukin 6	0.102
Ccr1	chemokine (C-C motif) receptor 1	0.089
Slfn4	schlafen 4	0.085
Olr1	oxidized low density lipoprotein (lectin-like) receptor 1	0.083
Clec4e	C-type lectin domain family 4, member e	0.080
Clec4d	C-type lectin domain family 4, member d	0.077
Cxcl2	chemokine (C-X-C motif) ligand 2	0.074
Chi3l4	chitinase 3-like 4	0.072	Human
Selp	selectin, platelet	0.069
Ccr2	chemokine (C-C motif) receptor 2	0.069
Adam8	a disintegrin and metallopeptidase domain 8	0.066
Tnfrsf9	tumor necrosis factor receptor superfamily, member 9	0.063
Il1r1	interleukin 1 receptor, type I	0.063	Mouse
Il1rn	interleukin 1 receptor antagonist	0.060
Fpr2	formyl peptide receptor 2	0.057
Il33	interleukin 33	0.057
Tlr4	toll-like receptor 4	0.049
Cd80	CD80 antigen	0.046
Fgf7	fibroblast growth factor 7	0.042
Sla	src-like adaptor	0.040
Ccl6	chemokine (C-C motif) ligand 6	0.039
Tnfrsf1a	tumor necrosis factor receptor superfamily, member 1a	0.038
Emr1	EGF-like module containing, mucin-like, hormone receptor-like sequence 1	0.037
Il18r1	interleukin 18 receptor 1	0.035	Mouse
Tnfrsf1b	tumor necrosis factor receptor superfamily, member 1b	0.035
Ngp	neutrophilic granule protein	0.033
Ptger2	prostaglandin E receptor 2 (subtype EP2)	0.032
Lyz2	lysozyme 2	0.031
Msr1	macrophage scavenger receptor 1	0.031
Cd86	CD86 antigen	0.030
S100a8	S100 calcium binding protein A8 (calgranulin A)	0.027
Tollip	toll interacting protein	0.026
Unc93b1	unc-93 homolog B1 (C. elegans)	0.024
Cd33	CD33 antigen	0.023
Klrb1b	killer cell lectin-like receptor subfamily B member 1B	0.022
Lair1	leukocyte-associated Ig-like receptor 1	0.022
Csf3r	colony stimulating factor 3 receptor (granulocyte)	0.022
Plaur	plasminogen activator, urokinase receptor	0.022
Mpeg1	macrophage expressed gene 1	0.021
Plek	pleckstrin	0.020
Fgr	Gardner-Rasheed feline sarcoma viral (Fgr) oncogene homolog	0.020
Niacr1	niacin receptor 1	0.020
Ear2	eosinophil-associated, ribonuclease A family, member 2	0.020
F10	coagulation factor X	0.019
Ncf1	neutrophil cytosolic factor 1	0.019
Klra2	killer cell lectin-like receptor, subfamily A, member 2	0.019
Tbxas1	thromboxane A synthase 1, platelet	0.019
Pparg	peroxisome proliferator activated receptor gamma	0.018
Spp1	secreted phosphoprotein 1	0.018
Ebi3	Epstein-Barr virus induced gene 3	0.018
1100001G20Rik	RIKEN cDNA 1100001G20 gene	0.018
Cpa3	carboxypeptidase A3, mast cell	0.018
Cd300lf	CD300 antigen like family member F	0.018
Lilrb4	leukocyte immunoglobulin-like receptor, subfamily B, member 4	0.017
Cxcl1	chemokine (C-X-C motif) ligand 1	0.017
Traf1	TNF receptor-associated factor 1	0.017
Gda	guanine deaminase	0.017
Bst1	bone marrow stromal cell antigen 1	0.016
Pla2g7	phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)	0.016
Ltf	lactotransferrin	0.016
Ifitm6	interferon induced transmembrane protein 6	0.015
Cysltr1	cysteinyl leukotriene receptor 1	0.015
Osmr	oncostatin M receptor	0.015
Pilra	paired immunoglobin-like type 2 receptor alpha	0.015
Icam5	intercellular adhesion molecule 5, telencephalin	0.015
Gpr97	G protein-coupled receptor 97	0.015
1600029D21Rik	RIKEN cDNA 1600029D21 gene	0.015
Slc10a6	solute carrier family 10 (sodium/bile acid cotransporter family), member 6	0.015
Mmp12	matrix metallopeptidase 12	0.015
Irg1	immunoresponsive gene 1	0.014
Emr4	EGF-like module containing, mucin-like, hormone receptor-like sequence 4	0.014
Pld4	phospholipase D family, member 4	0.014
Ptgs1	prostaglandin-endoperoxide synthase 1	0.014
Il10ra	interleukin 10 receptor, alpha	0.014
Il18	interleukin 18	0.014
Tnfrsf18	tumor necrosis factor receptor superfamily, member 18	0.014
Fcgr3	Fc receptor, IgG, low affinity III	0.014
Hdc	histidine decarboxylase	0.014
Serpina3n	serine (or cysteine) peptidase inhibitor, clade A, member 3N	0.014
Saa3	serum amyloid A 3	0.014
Slc7a11	solute carrier family 7 (cationic amino acid transporter, y+ system), member 11	0.013
Ch25h	cholesterol 25-hydroxylase	0.013
LOC677008	natural killer cell receptor 2B4-like	0.013
Lif	leukemia inhibitory factor	0.013
Chi3l1	chitinase 3-like 1	0.013
Ccl2	chemokine (C-C motif) ligand 2	0.013
Trem1	triggering receptor expressed on myeloid cells 1	0.013
Fpr1	formyl peptide receptor 1	0.013
Havcr2	hepatitis A virus cellular receptor 2	0.013
Cd14	CD14 antigen	0.013
Hc	hemolytic complement	0.012
Alox5ap	arachidonate 5-lipoxygenase activating protein	0.012
Gcnt2	glucosaminyl (N-acetyl) transferase 2, I-branching enzyme	0.012
Ctla4	cytotoxic T-lymphocyte-associated protein 4	0.012
C1qb	complement component 1, q subcomponent, beta polypeptide	0.012
Acpp	acid phosphatase, prostate	0.012
Clec7a	C-type lectin domain family 7, member a	0.012
Ccl3	chemokine (C-C motif) ligand 3	0.012
Has2	hyaluronan synthase 2	0.012
Clec4n	C-type lectin domain family 4, member n	0.012
Ms4a2	membrane-spanning 4-domains, subfamily A, member 2	0.012
Il4ra	interleukin 4 receptor, alpha	0.012
Mefv	Mediterranean fever	0.011
Cxcl5	chemokine (C-X-C motif) ligand 5	0.011
Klra17	killer cell lectin-like receptor, subfamily A, member 17	0.011
Clca1	chloride channel calcium activated 1	0.011
Slfn1	schlafen 1	0.011
Dram1	DNA-damage regulated autophagy modulator 1	0.011
Itgae	integrin alpha E, epithelial-associated	0.011
Il13ra1	interleukin 13 receptor, alpha 1	0.011
Lilrb3	leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3	0.011
Adora2b	adenosine A2b receptor	0.011
Il2ra	interleukin 2 receptor, alpha chain	0.011
Gjb6	gap junction protein, beta 6	0.011
Klrk1	killer cell lectin-like receptor subfamily K, member 1	0.011
Cd300a	CD300A antigen	0.011
Tll1	tolloid-like	0.011
Serpinb1a	serine (or cysteine) peptidase inhibitor, clade B, member 1a	0.010
Cd177	CD177 antigen	0.010
Itgam	integrin alpha M	0.010
Agr2	anterior gradient 2 (Xenopus laevis)	0.010
Galnt6	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 6	0.010
Pion	pigeon homolog (Drosophila)	0.010
Il1a	interleukin 1 alpha	0.010
F7	coagulation factor VII	0.010
Fas	Fas (TNF receptor superfamily member 6)	0.010