IMP

Process View

Mus musculus

25 genes annotated in mouse

nitric oxide metabolic process

The chemical reactions and pathways involving nitric oxide, nitrogen monoxide (NO), a colorless gas only slightly soluble in water.

Loading network...

In addition to gene-name show these genes:

Known genes in the process in mouse Include functional analogs

Network Filters

Minimum relationship confidence:

Maximum number of genes:

Highlight known relationships in gold.

Graphical Options

Adjust edge length:

Adjust node size:

Fixed layout

Black background

Low confidence color:

Med confidence color:

High confidence color:

Hide the legend in the network

Save Options

Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "nitric oxide metabolic process"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "nitric oxide metabolic process" (in gray)

Name	Description	Probability	Func Analog Organism
Tlr4	toll-like receptor 4	0.947
Nos2	nitric oxide synthase 2, inducible	0.930
Lepr	leptin receptor	0.894
Nos1	nitric oxide synthase 1, neuronal	0.786
B2m	beta-2 microglobulin	0.751
Klra9	killer cell lectin-like receptor subfamily A, member 9	0.734
Tnf	tumor necrosis factor	0.718
H2-K1	histocompatibility 2, K1, K region	0.718	Mouse
Relb	avian reticuloendotheliosis viral (v-rel) oncogene related B	0.717
H2-D1	histocompatibility 2, D region locus 1	0.620	Mouse
Ptgs2	prostaglandin-endoperoxide synthase 2	0.573	Rat
Cav1	caveolin 1, caveolae protein	0.507
Ccl2	chemokine (C-C motif) ligand 2	0.456
Nos3	nitric oxide synthase 3, endothelial cell	0.343
Lyz2	lysozyme 2	0.329
Ccr2	chemokine (C-C motif) receptor 2	0.319
Ren1	renin 1 structural	0.266
Klrk1	killer cell lectin-like receptor subfamily K, member 1	0.254
Atxn1	ataxin 1	0.243
Klrc1	killer cell lectin-like receptor subfamily C, member 1	0.221	Mouse
Myd88	myeloid differentiation primary response gene 88	0.218
Tgfb1	transforming growth factor, beta 1	0.203
Insr	insulin receptor	0.202	Human
Esr1	estrogen receptor 1 (alpha)	0.156	Human
Plau	plasminogen activator, urokinase	0.134
Clec4n	C-type lectin domain family 4, member n	0.122
Vdr	vitamin D receptor	0.118
Tlr2	toll-like receptor 2	0.115
Pparg	peroxisome proliferator activated receptor gamma	0.109
Mmp9	matrix metallopeptidase 9	0.109
Ar	androgen receptor	0.107
Il10	interleukin 10	0.102
Klrd1	killer cell lectin-like receptor, subfamily D, member 1	0.099	Mouse
H2-Q7	histocompatibility 2, Q region locus 7	0.096
Hsp90aa1	heat shock protein 90, alpha (cytosolic), class A member 1	0.091
Pyhin1	pyrin and HIN domain family, member 1	0.086
H2-Q6	histocompatibility 2, Q region locus 6	0.083
Cd180	CD180 antigen	0.083	Mouse
Chordc1	cysteine and histidine-rich domain (CHORD)-containing, zinc-binding protein 1	0.078
Ptrf	polymerase I and transcript release factor	0.077
Il6	interleukin 6	0.075
Il1a	interleukin 1 alpha	0.071
Cp	ceruloplasmin	0.070
Casp4	caspase 4, apoptosis-related cysteine peptidase	0.070
Col1a1	collagen, type I, alpha 1	0.068
Gcet2	germinal center expressed transcript 2	0.066
Agtr1a	angiotensin II receptor, type 1a	0.066
Asap1	ArfGAP with SH# domain, ankyrin repeat and PH domain1	0.063
Wt1	Wilms tumor 1 homolog	0.062
Cd44	CD44 antigen	0.062
Lif	leukemia inhibitory factor	0.059
Apoe	apolipoprotein E	0.058
Hsp90ab1	heat shock protein 90 alpha (cytosolic), class B member 1	0.057	Mouse
Dmd	dystrophin, muscular dystrophy	0.057
Vhl	von Hippel-Lindau tumor suppressor	0.056
Map3k8	mitogen-activated protein kinase kinase kinase 8	0.055
Plat	plasminogen activator, tissue	0.053
Aoah	acyloxyacyl hydrolase	0.052
Invs	inversin	0.050
Il7r	interleukin 7 receptor	0.050
Ncr1	natural cytotoxicity triggering receptor 1	0.050
Ms4a4c	membrane-spanning 4-domains, subfamily A, member 4C	0.048
H2-Eb1	histocompatibility 2, class II antigen E beta	0.047
Ccr6	chemokine (C-C motif) receptor 6	0.046
Hspa8	heat shock protein 8	0.046
Ghr	growth hormone receptor	0.046
Cd14	CD14 antigen	0.045
Nt5e	5' nucleotidase, ecto	0.045
Fasl	Fas ligand (TNF superfamily, member 6)	0.044
Klrb1b	killer cell lectin-like receptor subfamily B member 1B	0.044
Lair1	leukocyte-associated Ig-like receptor 1	0.044
Nr3c1	nuclear receptor subfamily 3, group C, member 1	0.044
Gnas	GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus	0.043
F9	coagulation factor IX	0.042
Fpr1	formyl peptide receptor 1	0.041
Gzmk	granzyme K	0.041
Nfkbia	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha	0.040
Gzma	granzyme A	0.039
Itgb3	integrin beta 3	0.038
Ccr5	chemokine (C-C motif) receptor 5	0.038
Blk	B lymphoid kinase	0.037
Vegfa	vascular endothelial growth factor A	0.036
Hsph1	heat shock 105kDa/110kDa protein 1	0.036
Ifna1	interferon alpha 1	0.036
Thbd	thrombomodulin	0.036
Cys1	cystin 1	0.035
Casp1	caspase 1	0.035
Nr2f2	nuclear receptor subfamily 2, group F, member 2	0.034
Bcar1	breast cancer anti-estrogen resistance 1	0.034
Ptprc	protein tyrosine phosphatase, receptor type, C	0.033
Prnp	prion protein	0.033
Spna1	spectrin alpha 1	0.033
Slc40a1	solute carrier family 40 (iron-regulated transporter), member 1	0.031
Adam23	a disintegrin and metallopeptidase domain 23	0.031
Slc7a2	solute carrier family 7 (cationic amino acid transporter, y+ system), member 2	0.030
Tnfrsf1b	tumor necrosis factor receptor superfamily, member 1b	0.029
Cxcr6	chemokine (C-X-C motif) receptor 6	0.029
Itgb1	integrin beta 1 (fibronectin receptor beta)	0.029
Cblb	Casitas B-lineage lymphoma b	0.028
Emr4	EGF-like module containing, mucin-like, hormone receptor-like sequence 4	0.028
Il10ra	interleukin 10 receptor, alpha	0.027
Ccr3	chemokine (C-C motif) receptor 3	0.027
D19Wsu162e	DNA segment, Chr 19, Wayne State University 162, expressed	0.027
Pilrb1	paired immunoglobin-like type 2 receptor beta 1	0.026
Cnr1	cannabinoid receptor 1 (brain)	0.026
Casp12	caspase 12	0.026
F2rl2	coagulation factor II (thrombin) receptor-like 2	0.026
Axl	AXL receptor tyrosine kinase	0.025
Cybb	cytochrome b-245, beta polypeptide	0.025
Emr1	EGF-like module containing, mucin-like, hormone receptor-like sequence 1	0.025
Lmna	lamin A	0.024
Ahsg	alpha-2-HS-glycoprotein	0.024
Stat1	signal transducer and activator of transcription 1	0.024
Itgal	integrin alpha L	0.023
Shisa5	shisa homolog 5 (Xenopus laevis)	0.023
Unc93b1	unc-93 homolog B1 (C. elegans)	0.023
Notch2	Notch gene homolog 2 (Drosophila)	0.023
Klrb1c	killer cell lectin-like receptor subfamily B member 1C	0.023
Lep	leptin	0.023
Il2rg	interleukin 2 receptor, gamma chain	0.023
Ppargc1a	peroxisome proliferative activated receptor, gamma, coactivator 1 alpha	0.022
Gzmb	granzyme B	0.022
Igf1r	insulin-like growth factor I receptor	0.022
Mavs	mitochondrial antiviral signaling protein	0.022
Slamf7	SLAM family member 7	0.022
Fcrla	Fc receptor-like A	0.021
Ly96	lymphocyte antigen 96	0.021
Klra2	killer cell lectin-like receptor, subfamily A, member 2	0.021	Mouse
Nr1h3	nuclear receptor subfamily 1, group H, member 3	0.021
Il18rap	interleukin 18 receptor accessory protein	0.021
Il2ra	interleukin 2 receptor, alpha chain	0.021
Hspd1	heat shock protein 1 (chaperonin)	0.021
C9	complement component 9	0.021
Ly9	lymphocyte antigen 9	0.020
Crim1	cysteine rich transmembrane BMP regulator 1 (chordin like)	0.020
Csf1	colony stimulating factor 1 (macrophage)	0.020
Meox2	mesenchyme homeobox 2	0.020
Pten	phosphatase and tensin homolog	0.020
H2-Q5	histocompatibility 2, Q region locus 5	0.020
Cyp4v3	cytochrome P450, family 4, subfamily v, polypeptide 3	0.020
Grpr	gastrin releasing peptide receptor	0.019
Clec4e	C-type lectin domain family 4, member e	0.019
Cyp3a11	cytochrome P450, family 3, subfamily a, polypeptide 11	0.019
Psmb9	proteasome (prosome, macropain) subunit, beta type 9 (large multifunctional peptidase 2)	0.019
Csf3r	colony stimulating factor 3 receptor (granulocyte)	0.019
Socs1	suppressor of cytokine signaling 1	0.019
Bicc1	bicaudal C homolog 1 (Drosophila)	0.019
Mcoln2	mucolipin 2	0.019
Sardh	sarcosine dehydrogenase	0.018
Saa4	serum amyloid A 4	0.018
Itga4	integrin alpha 4	0.018
Cyp2b13	cytochrome P450, family 2, subfamily b, polypeptide 13	0.018
Fosb	FBJ osteosarcoma oncogene B	0.018
Ptafr	platelet-activating factor receptor	0.018
Clec7a	C-type lectin domain family 7, member a	0.018	Mouse
Cyp2a12	cytochrome P450, family 2, subfamily a, polypeptide 12	0.017
Mpeg1	macrophage expressed gene 1	0.017
Gnrh1	gonadotropin releasing hormone 1	0.017
Prkce	protein kinase C, epsilon	0.017
Calca	calcitonin/calcitonin-related polypeptide, alpha	0.017
Gpr65	G-protein coupled receptor 65	0.017
AA408251	expressed sequence AA408251	0.017
Abcg3	ATP-binding cassette, sub-family G (WHITE), member 3	0.017
Cxcl9	chemokine (C-X-C motif) ligand 9	0.017
Elf1	E74-like factor 1	0.017
Klra8	killer cell lectin-like receptor, subfamily A, member 8	0.016
Smad3	MAD homolog 3 (Drosophila)	0.016
Ch25h	cholesterol 25-hydroxylase	0.016
Prlhr	prolactin releasing hormone receptor	0.016
Cd33	CD33 antigen	0.016
Akr1c6	aldo-keto reductase family 1, member C6	0.016
Klra7	killer cell lectin-like receptor, subfamily A, member 7	0.015	Mouse
Ahi1	Abelson helper integration site 1	0.015
F7	coagulation factor VII	0.015
Megf8	multiple EGF-like-domains 8	0.015
Clec4a2	C-type lectin domain family 4, member a2	0.015
Spry4	sprouty homolog 4 (Drosophila)	0.015
St6galnac1	ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1	0.015
H2-Q8	histocompatibility 2, Q region locus 8	0.015
Ccr8	chemokine (C-C motif) receptor 8	0.015
Agtr2	angiotensin II receptor, type 2	0.015
Timp4	tissue inhibitor of metalloproteinase 4	0.015
Nfkbiz	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta	0.015
Ticam1	toll-like receptor adaptor molecule 1	0.015
Thpo	thrombopoietin	0.015
Cysltr1	cysteinyl leukotriene receptor 1	0.015
Dpysl2	dihydropyrimidinase-like 2	0.015
Cytip	cytohesin 1 interacting protein	0.014
Egr1	early growth response 1	0.014
Gcgr	glucagon receptor	0.014
Mat1a	methionine adenosyltransferase I, alpha	0.014
Twsg1	twisted gastrulation homolog 1 (Drosophila)	0.014
Tap1	transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)	0.014
Tap2	transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)	0.014
Mapk14	mitogen-activated protein kinase 14	0.014
Stat3	signal transducer and activator of transcription 3	0.014
Mup4	major urinary protein 4	0.014
Cxcr3	chemokine (C-X-C motif) receptor 3	0.014
Birc3	baculoviral IAP repeat-containing 3	0.014
Cd19	CD19 antigen	0.014
C3ar1	complement component 3a receptor 1	0.014
Slfn1	schlafen 1	0.014
Src	Rous sarcoma oncogene	0.014
Itih3	inter-alpha trypsin inhibitor, heavy chain 3	0.014
Maged1	melanoma antigen, family D, 1	0.014
Kynu	kynureninase (L-kynurenine hydrolase)	0.014
Socs3	suppressor of cytokine signaling 3	0.013
Tapbp	TAP binding protein	0.013
Socs5	suppressor of cytokine signaling 5	0.013
P2rx4	purinergic receptor P2X, ligand-gated ion channel 4	0.013
Nppb	natriuretic peptide type B	0.013
P2rx2	purinergic receptor P2X, ligand-gated ion channel, 2	0.013	Mouse
Ms4a6b	membrane-spanning 4-domains, subfamily A, member 6B	0.013
Car1	carbonic anhydrase 1	0.013
Gcnt1	glucosaminyl (N-acetyl) transferase 1, core 2	0.013
Eya4	eyes absent 4 homolog (Drosophila)	0.013
Pdgfrb	platelet derived growth factor receptor, beta polypeptide	0.013
Arl4d	ADP-ribosylation factor-like 4D	0.013
Prdm1	PR domain containing 1, with ZNF domain	0.013
Siglec1	sialic acid binding Ig-like lectin 1, sialoadhesin	0.013
Cd300a	CD300A antigen	0.013
Klk1b4	kallikrein 1-related pepidase b4	0.012
Cd84	CD84 antigen	0.012
Haao	3-hydroxyanthranilate 3,4-dioxygenase	0.012
Hsd3b7	hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7	0.012
Tnfsf11	tumor necrosis factor (ligand) superfamily, member 11	0.012
Cyp2c70	cytochrome P450, family 2, subfamily c, polypeptide 70	0.012
Csf2rb2	colony stimulating factor 2 receptor, beta 2, low-affinity (granulocyte-macrophage)	0.012
BC026585	cDNA sequence BC026585	0.012
Pgr	progesterone receptor	0.012
Gpr132	G protein-coupled receptor 132	0.012
Prkg1	protein kinase, cGMP-dependent, type I	0.012
Dhh	desert hedgehog	0.012
Mlf2	myeloid leukemia factor 2	0.012
Slc12a1	solute carrier family 12, member 1	0.012
Cdkn2c	cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)	0.012
Epsti1	epithelial stromal interaction 1 (breast)	0.012
Klrb1f	killer cell lectin-like receptor subfamily B member 1F	0.012
Klre1	killer cell lectin-like receptor family E member 1	0.012	Mouse
Hspa5	heat shock protein 5	0.012
Il12b	interleukin 12b	0.012
Hfe	hemochromatosis	0.012	Mouse
Tll1	tolloid-like	0.012
Ifngr2	interferon gamma receptor 2	0.012
Msr1	macrophage scavenger receptor 1	0.012
Cxcl10	chemokine (C-X-C motif) ligand 10	0.012
Clcn5	chloride channel 5	0.012
AW112010	expressed sequence AW112010	0.012
Ms4a6c	membrane-spanning 4-domains, subfamily A, member 6C	0.012
Itga2	integrin alpha 2	0.011
Cpa3	carboxypeptidase A3, mast cell	0.011
Nfkbie	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon	0.011
Ubc	ubiquitin C	0.011
Kcns2	K+ voltage-gated channel, subfamily S, 2	0.011
Lgals8	lectin, galactose binding, soluble 8	0.011
Tnfsf8	tumor necrosis factor (ligand) superfamily, member 8	0.011
Hmox1	heme oxygenase (decycling) 1	0.011
Ifnar1	interferon (alpha and beta) receptor 1	0.011
Ephx1	epoxide hydrolase 1, microsomal	0.011
Cd300ld	CD300 molecule-like family member d	0.011
Slc7a11	solute carrier family 7 (cationic amino acid transporter, y+ system), member 11	0.011
Ifng	interferon gamma	0.011
Cmah	cytidine monophospho-N-acetylneuraminic acid hydroxylase	0.011
Umod	uromodulin	0.011
Mx1	myxovirus (influenza virus) resistance 1	0.011
Bcl2	B-cell leukemia/lymphoma 2	0.011
Tnnc1	troponin C, cardiac/slow skeletal	0.011
Mb	myoglobin	0.011
Aim2	absent in melanoma 2	0.011
Mstn	myostatin	0.011
Khdc1b	KH domain containing 1B	0.011
Ciita	class II transactivator	0.011
Rgs18	regulator of G-protein signaling 18	0.011
Sh2d1a	SH2 domain protein 1A	0.011
Tnni1	troponin I, skeletal, slow 1	0.011
Pck1	phosphoenolpyruvate carboxykinase 1, cytosolic	0.011
Igsf6	immunoglobulin superfamily, member 6	0.011
Vcam1	vascular cell adhesion molecule 1	0.011
Pkd2	polycystic kidney disease 2	0.011
Nr1i3	nuclear receptor subfamily 1, group I, member 3	0.011
Saa2	serum amyloid A 2	0.011
Fpr3	formyl peptide receptor 3	0.011
Apobec1	apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1	0.011
H2-Ab1	histocompatibility 2, class II antigen A, beta 1	0.010
Itgb1bp2	integrin beta 1 binding protein 2	0.010
Gpr18	G protein-coupled receptor 18	0.010
P2ry12	purinergic receptor P2Y, G-protein coupled 12	0.010
Nphp4	nephronophthisis 4 (juvenile) homolog (human)	0.010
Myl2	myosin, light polypeptide 2, regulatory, cardiac, slow	0.010
P2ry13	purinergic receptor P2Y, G-protein coupled 13	0.010
Ticam2	toll-like receptor adaptor molecule 2	0.010	Mouse
Fut1	fucosyltransferase 1	0.010
Nkg7	natural killer cell group 7 sequence	0.010
Bmpr2	bone morphogenic protein receptor, type II (serine/threonine kinase)	0.010
Chrnb2	cholinergic receptor, nicotinic, beta polypeptide 2 (neuronal)	0.010
Hrg	histidine-rich glycoprotein	0.010
Nek8	NIMA (never in mitosis gene a)-related expressed kinase 8	0.010
Ucp3	uncoupling protein 3 (mitochondrial, proton carrier)	0.010