IMP

Process View

Homo sapiens

2 genes annotated in human

fatty acid omega oxidation

A fatty acid oxidation process in which the methyl group at the end of the fatty acid molecule (the omega carbon) is first oxidized to a hydroxyl group, then to an oxo group, and finally to a carboxyl group. The long chain dicarboxylates derived from omega-oxidation then enter the beta-oxidation pathway for further degradation.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "fatty acid omega oxidation"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "fatty acid omega oxidation" (in gray)

Name	Description	Probability	Func Analog Organism
ADH1C	alcohol dehydrogenase 1C (class I), gamma polypeptide	0.999
CYP2C9	cytochrome P450, family 2, subfamily C, polypeptide 9	0.950
CYP4F12	cytochrome P450, family 4, subfamily F, polypeptide 12	0.934	Human
CYP4F2	cytochrome P450, family 4, subfamily F, polypeptide 2	0.853	Human
ADH1A	alcohol dehydrogenase 1A (class I), alpha polypeptide	0.835	Human
CYP4F3	cytochrome P450, family 4, subfamily F, polypeptide 3	0.833	Human
CYP3A43	cytochrome P450, family 3, subfamily A, polypeptide 43	0.781
CYP2B6	cytochrome P450, family 2, subfamily B, polypeptide 6	0.519
ADH1B	alcohol dehydrogenase 1B (class I), beta polypeptide	0.438	Human
C6	complement component 6	0.369
CYP4A11	cytochrome P450, family 4, subfamily A, polypeptide 11	0.294	Human
CYP2C19	cytochrome P450, family 2, subfamily C, polypeptide 19	0.240
ANGPTL3	angiopoietin-like 3	0.215
AADAC	arylacetamide deacetylase (esterase)	0.211
HMGCS2	3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial)	0.208
ABCA8	ATP-binding cassette, sub-family A (ABC1), member 8	0.197
SULT1B1	sulfotransferase family, cytosolic, 1B, member 1	0.191
C8A	complement component 8, alpha polypeptide	0.157
CYP3A5	cytochrome P450, family 3, subfamily A, polypeptide 5	0.153
CYP2C18	cytochrome P450, family 2, subfamily C, polypeptide 18	0.140
ABCC2	ATP-binding cassette, sub-family C (CFTR/MRP), member 2	0.139
KNG1	kininogen 1	0.133
ABCA6	ATP-binding cassette, sub-family A (ABC1), member 6	0.131
ECM2	extracellular matrix protein 2, female organ and adipocyte specific	0.130
PLG	plasminogen	0.117
FABP1	fatty acid binding protein 1, liver	0.110
AKR1C4	aldo-keto reductase family 1, member C4 (chlordecone reductase; 3-alpha hydroxysteroid dehydrogenase, type I; dihydrodiol dehydrogenase 4)	0.109
CYP3A4	cytochrome P450, family 3, subfamily A, polypeptide 4	0.108
PAH	phenylalanine hydroxylase	0.106
AZGP1	alpha-2-glycoprotein 1, zinc-binding	0.106
OTC	ornithine carbamoyltransferase	0.105
UGT1A3	UDP glucuronosyltransferase 1 family, polypeptide A3	0.098
G6PC	glucose-6-phosphatase, catalytic subunit	0.078
CYP2C8	cytochrome P450, family 2, subfamily C, polypeptide 8	0.078
FMO4	flavin containing monooxygenase 4	0.077
ASPA	aspartoacylase	0.076
C7	complement component 7	0.076
SULT2A1	sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1	0.074
CDHR5	cadherin-related family member 5	0.067
CYP3A7	cytochrome P450, family 3, subfamily A, polypeptide 7	0.064
SULT1E1	sulfotransferase family 1E, estrogen-preferring, member 1	0.057
GSTA3	glutathione S-transferase alpha 3	0.057
FMO3	flavin containing monooxygenase 3	0.057
DIO1	deiodinase, iodothyronine, type I	0.055
CYP4B1	cytochrome P450, family 4, subfamily B, polypeptide 1	0.053	Human
F9	coagulation factor IX	0.052
SLC22A7	solute carrier family 22 (organic anion transporter), member 7	0.051
MAT1A	methionine adenosyltransferase I, alpha	0.049
HAL	histidine ammonia-lyase	0.046
BAAT	bile acid CoA: amino acid N-acyltransferase (glycine N-choloyltransferase)	0.046
HPD	4-hydroxyphenylpyruvate dioxygenase	0.046
FMO2	flavin containing monooxygenase 2 (non-functional)	0.045
NAT2	N-acetyltransferase 2 (arylamine N-acetyltransferase)	0.044
ANXA13	annexin A13	0.041
HRG	histidine-rich glycoprotein	0.041
ALDH3A1	aldehyde dehydrogenase 3 family, member A1	0.040
ALDOB	aldolase B, fructose-bisphosphate	0.039
GLYAT	glycine-N-acyltransferase	0.038
OGN	osteoglycin	0.037
CYP2E1	cytochrome P450, family 2, subfamily E, polypeptide 1	0.037
SLC2A2	solute carrier family 2 (facilitated glucose transporter), member 2	0.036
BHMT	betaine--homocysteine S-methyltransferase	0.036
SCGB2A1	secretoglobin, family 2A, member 1	0.035
C8B	complement component 8, beta polypeptide	0.035
HGD	homogentisate 1,2-dioxygenase	0.035
PLIN1	perilipin 1	0.035
PRLR	prolactin receptor	0.034
ADH6	alcohol dehydrogenase 6 (class V)	0.034	Human
DEFB1	defensin, beta 1	0.033
KRT13	keratin 13	0.033
KRT4	keratin 4	0.032
MTTP	microsomal triglyceride transfer protein	0.031
PIP	prolactin-induced protein	0.030
ARG1	arginase, liver	0.030
SLC17A1	solute carrier family 17 (sodium phosphate), member 1	0.029
C4BPA	complement component 4 binding protein, alpha	0.029
CLDN8	claudin 8	0.029
EPHX2	epoxide hydrolase 2, cytoplasmic	0.028
FABP2	fatty acid binding protein 2, intestinal	0.028
AKR1D1	aldo-keto reductase family 1, member D1 (delta 4-3-ketosteroid-5-beta-reductase)	0.028
AOX1	aldehyde oxidase 1	0.028
DNASE1L3	deoxyribonuclease I-like 3	0.027
MYH11	myosin, heavy chain 11, smooth muscle	0.027
SERPINA6	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 6	0.026
GBA3	glucosidase, beta, acid 3 (cytosolic)	0.025
ACSM5	acyl-CoA synthetase medium-chain family member 5	0.025
F13B	coagulation factor XIII, B polypeptide	0.025
BBOX1	butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1	0.024
SCNN1B	sodium channel, nonvoltage-gated 1, beta	0.024
ADH4	alcohol dehydrogenase 4 (class II), pi polypeptide	0.024	Human
C10orf116	chromosome 10 open reading frame 116	0.024
HSD17B2	hydroxysteroid (17-beta) dehydrogenase 2	0.023
CYP2J2	cytochrome P450, family 2, subfamily J, polypeptide 2	0.023
ABCB11	ATP-binding cassette, sub-family B (MDR/TAP), member 11	0.023
CFHR4	complement factor H-related 4	0.023
IL22RA1	interleukin 22 receptor, alpha 1	0.023
ADIPOQ	adiponectin, C1Q and collagen domain containing	0.022
C9orf68	chromosome 9 open reading frame 68	0.022
DAO	D-amino-acid oxidase	0.022
FETUB	fetuin B	0.022
F5	coagulation factor V (proaccelerin, labile factor)	0.022
APOF	apolipoprotein F	0.021
C4BPB	complement component 4 binding protein, beta	0.021
ACADL	acyl-CoA dehydrogenase, long chain	0.020
AKR1B10	aldo-keto reductase family 1, member B10 (aldose reductase)	0.020
NR1H4	nuclear receptor subfamily 1, group H, member 4	0.019
RDH16	retinol dehydrogenase 16 (all-trans)	0.019
SERPINB13	serpin peptidase inhibitor, clade B (ovalbumin), member 13	0.019
CLCA2	chloride channel accessory 2	0.019
TMPRSS4	transmembrane protease, serine 4	0.019
SCGB1D2	secretoglobin, family 1D, member 2	0.019
FLG	filaggrin	0.019
LRRC31	leucine rich repeat containing 31	0.019
SCNN1A	sodium channel, nonvoltage-gated 1 alpha	0.019
CLCA4	chloride channel accessory 4	0.018
AKR1C1	aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase)	0.018
MAOA	monoamine oxidase A	0.018
ACE2	angiotensin I converting enzyme (peptidyl-dipeptidase A) 2	0.018
MEP1A	meprin A, alpha (PABA peptide hydrolase)	0.018
AFM	afamin	0.018
ADRA1A	adrenergic, alpha-1A-, receptor	0.018
CRISP2	cysteine-rich secretory protein 2	0.018
UPK1B	uroplakin 1B	0.018
FMO5	flavin containing monooxygenase 5	0.017
SLC26A3	solute carrier family 26, member 3	0.017
ANXA10	annexin A10	0.017
SLC10A1	solute carrier family 10 (sodium/bile acid cotransporter family), member 1	0.017
FABP4	fatty acid binding protein 4, adipocyte	0.017
HHLA2	HERV-H LTR-associating 2	0.017
APOD	apolipoprotein D	0.017
ATP10B	ATPase, class V, type 10B	0.017
PSCA	prostate stem cell antigen	0.017
POF1B	premature ovarian failure, 1B	0.017
DPYS	dihydropyrimidinase	0.017
CYP4F8	cytochrome P450, family 4, subfamily F, polypeptide 8	0.016	Human
CES1	carboxylesterase 1	0.016
LAMA2	laminin, alpha 2	0.016
UNC93A	unc-93 homolog A (C. elegans)	0.016
BHMT2	betaine--homocysteine S-methyltransferase 2	0.016
DPT	dermatopontin	0.016
VTCN1	V-set domain containing T cell activation inhibitor 1	0.016
RARRES2	retinoic acid receptor responder (tazarotene induced) 2	0.016
TMC5	transmembrane channel-like 5	0.015
POU1F1	POU class 1 homeobox 1	0.015
SLC22A1	solute carrier family 22 (organic cation transporter), member 1	0.015
SULT2B1	sulfotransferase family, cytosolic, 2B, member 1	0.015
MAOB	monoamine oxidase B	0.015
CRISP3	cysteine-rich secretory protein 3	0.015
NAT8	N-acetyltransferase 8 (GCN5-related, putative)	0.015
PDE4DIP	phosphodiesterase 4D interacting protein	0.015
GSTT1	glutathione S-transferase theta 1	0.014
C5orf4	chromosome 5 open reading frame 4	0.014
OMD	osteomodulin	0.014
ACOX2	acyl-CoA oxidase 2, branched chain	0.014
CEACAM7	carcinoembryonic antigen-related cell adhesion molecule 7	0.014
CYP4A22	cytochrome P450, family 4, subfamily A, polypeptide 22	0.014	Human
MSMB	microseminoprotein, beta-	0.014
C2orf54	chromosome 2 open reading frame 54	0.014
C1orf129	chromosome 1 open reading frame 129	0.014
SGK2	serum/glucocorticoid regulated kinase 2	0.013
PCK1	phosphoenolpyruvate carboxykinase 1 (soluble)	0.013
CPB2	carboxypeptidase B2 (plasma)	0.013
GPX2	glutathione peroxidase 2 (gastrointestinal)	0.013
PIK3C2G	phosphoinositide-3-kinase, class 2, gamma polypeptide	0.013
CYP1A1	cytochrome P450, family 1, subfamily A, polypeptide 1	0.013
CYP4F11	cytochrome P450, family 4, subfamily F, polypeptide 11	0.013	Human
RGN	regucalcin (senescence marker protein-30)	0.013
AGR2	anterior gradient homolog 2 (Xenopus laevis)	0.013
PIPOX	pipecolic acid oxidase	0.013
GHR	growth hormone receptor	0.013
SPINK1	serine peptidase inhibitor, Kazal type 1	0.012
APOC3	apolipoprotein C-III	0.012
DSG1	desmoglein 1	0.012
HFE2	hemochromatosis type 2 (juvenile)	0.012
LIPC	lipase, hepatic	0.012
UGT2B17	UDP glucuronosyltransferase 2 family, polypeptide B17	0.012
RERGL	RERG/RAS-like	0.012
TIMP4	TIMP metallopeptidase inhibitor 4	0.012
ENPP3	ectonucleotide pyrophosphatase/phosphodiesterase 3	0.012
CPS1	carbamoyl-phosphate synthase 1, mitochondrial	0.012
TSPAN8	tetraspanin 8	0.012
GYS2	glycogen synthase 2 (liver)	0.012
IL5	interleukin 5 (colony-stimulating factor, eosinophil)	0.012
CHL1	cell adhesion molecule with homology to L1CAM (close homolog of L1)	0.012
CHRDL1	chordin-like 1	0.012
UGT2B4	UDP glucuronosyltransferase 2 family, polypeptide B4	0.012
SEMG2	semenogelin II	0.012
TMEM40	transmembrane protein 40	0.012
MOSC1	MOCO sulphurase C-terminal domain containing 1	0.012
SGCG	sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein)	0.012
TTPA	tocopherol (alpha) transfer protein	0.012
AKR1C2	aldo-keto reductase family 1, member C2 (dihydrodiol dehydrogenase 2; bile acid binding protein; 3-alpha hydroxysteroid dehydrogenase, type III)	0.011
CYP27A1	cytochrome P450, family 27, subfamily A, polypeptide 1	0.011
APOH	apolipoprotein H (beta-2-glycoprotein I)	0.011
REG3G	regenerating islet-derived 3 gamma	0.011
ZNF214	zinc finger protein 214	0.011
PON3	paraoxonase 3	0.011
CCL16	chemokine (C-C motif) ligand 16	0.011
VIL1	villin 1	0.011
FHL5	four and a half LIM domains 5	0.011
MUC13	mucin 13, cell surface associated	0.011
ABP1	amiloride binding protein 1 (amine oxidase (copper-containing))	0.011
GPR110	G protein-coupled receptor 110	0.011
LRRC19	leucine rich repeat containing 19	0.011
CEACAM8	carcinoembryonic antigen-related cell adhesion molecule 8	0.011
FCGBP	Fc fragment of IgG binding protein	0.011
CYP7A1	cytochrome P450, family 7, subfamily A, polypeptide 1	0.011
ALDH1L1	aldehyde dehydrogenase 1 family, member L1	0.011
SLC5A12	solute carrier family 5 (sodium/glucose cotransporter), member 12	0.011
METTL7A	methyltransferase like 7A	0.011
HNF4G	hepatocyte nuclear factor 4, gamma	0.011
SCEL	sciellin	0.011
BCAS1	breast carcinoma amplified sequence 1	0.010
IL20RA	interleukin 20 receptor, alpha	0.010
TTC22	tetratricopeptide repeat domain 22	0.010
CLRN3	clarin 3	0.010
OSGIN1	oxidative stress induced growth inhibitor 1	0.010
GPR128	G protein-coupled receptor 128	0.010
NTS	neurotensin	0.010
AGTR1	angiotensin II receptor, type 1	0.010
AKR1C3	aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II)	0.010
AQP7	aquaporin 7	0.010
CFD	complement factor D (adipsin)	0.010
UGT1A9	UDP glucuronosyltransferase 1 family, polypeptide A9	0.010