IMP
Process View
type 2 immune response
An immune response which is associated with resistance to extracellular organisms such as helminths and pathological conditions such as allergy, which is orchestrated by the production of particular cytokines, most notably IL-4, IL-5, IL-10, and IL-13, by any of a variety of cell types including T-helper 2 cells, eosinophils, basophils, mast cells, and nuocytes, resulting in enhanced production of certain antibody isotypes and other effects.
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In addition to gene-name show these genes:
Click on a gene's description to view its network relationships with genes known to be involved in "type 2 immune response"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | 0.978 | ||
| STAT6 | signal transducer and activator of transcription 6, interleukin-4 induced | 0.939 | Mouse | |
| NFKB2 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) | 0.917 | ||
| IL4R | interleukin 4 receptor | 0.760 | Mouse | |
| RXRA | retinoid X receptor, alpha | 0.746 | ||
| RELA | v-rel reticuloendotheliosis viral oncogene homolog A (avian) | 0.742 | ||
| RELB | v-rel reticuloendotheliosis viral oncogene homolog B | 0.727 | ||
| SIN3A | SIN3 homolog A, transcription regulator (yeast) | 0.560 | ||
| NFKBIE | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon | 0.540 | ||
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.536 | ||
| REL | v-rel reticuloendotheliosis viral oncogene homolog (avian) | 0.515 | ||
| HLA-DRA | major histocompatibility complex, class II, DR alpha | 0.491 | ||
| MED25 | mediator complex subunit 25 | 0.309 | ||
| NCOR2 | nuclear receptor corepressor 2 | 0.270 | ||
| IL2RG | interleukin 2 receptor, gamma | 0.098 | ||
| ZNF71 | zinc finger protein 71 | 0.080 | ||
| PTPN6 | protein tyrosine phosphatase, non-receptor type 6 | 0.075 | ||
| VDR | vitamin D (1,25- dihydroxyvitamin D3) receptor | 0.057 | ||
| IKBKB | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta | 0.047 | ||
| IL4 | interleukin 4 | 0.046 | ||
| MAP3K8 | mitogen-activated protein kinase kinase kinase 8 | 0.046 | ||
| IL6R | interleukin 6 receptor | 0.040 | ||
| NFKBIB | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta | 0.032 | ||
| INPP5D | inositol polyphosphate-5-phosphatase, 145kDa | 0.031 | ||
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.024 | ||
| NCOA1 | nuclear receptor coactivator 1 | 0.023 | ||
| HLA-DPA1 | major histocompatibility complex, class II, DP alpha 1 | 0.021 | ||
| PPARA | peroxisome proliferator-activated receptor alpha | 0.018 | ||
| IL8 | interleukin 8 | 0.018 | ||
| RIPK2 | receptor-interacting serine-threonine kinase 2 | 0.017 | ||
| CXCR4 | chemokine (C-X-C motif) receptor 4 | 0.017 | ||
| RARA | retinoic acid receptor, alpha | 0.016 | ||
| TNIP2 | TNFAIP3 interacting protein 2 | 0.016 | ||
| RXRB | retinoid X receptor, beta | 0.015 | ||
| ITGB1BP2 | integrin beta 1 binding protein (melusin) 2 | 0.013 | ||
| PRKD2 | protein kinase D2 | 0.013 | ||
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.011 | ||
| PYDC2 | pyrin domain containing 2 | 0.011 | ||
| HLA-DRB4 | major histocompatibility complex, class II, DR beta 4 | 0.011 | ||
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | 0.011 |