IMP
Process View
negative regulation of complement activation lectin pathway
Any process that stops, prevents, or reduces the rate of complement activation by the lectin pathway.
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Click on a gene's description to view its network relationships with genes known to be involved in "negative regulation of complement activation lectin pathway"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| APOE | apolipoprotein E | 1.000 | ||
| C1S | complement component 1, s subcomponent | 0.999 | ||
| TGM2 | transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase) | 0.997 | ||
| C1R | complement component 1, r subcomponent | 0.993 | ||
| CFH | complement factor H | 0.986 | ||
| CFI | complement factor I | 0.857 | ||
| HP | haptoglobin | 0.564 | ||
| APOC1 | apolipoprotein C-I | 0.459 | ||
| C3 | complement component 3 | 0.424 | Human | |
| CFB | complement factor B | 0.356 | ||
| SERPING1 | serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 | 0.333 | ||
| SEPT8 | septin 8 | 0.284 | ||
| PLTP | phospholipid transfer protein | 0.225 | ||
| MMP2 | matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase) | 0.197 | ||
| C1QA | complement component 1, q subcomponent, A chain | 0.168 | ||
| NNMT | nicotinamide N-methyltransferase | 0.167 | ||
| VSIG4 | V-set and immunoglobulin domain containing 4 | 0.140 | ||
| TNFRSF14 | tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator) | 0.121 | ||
| TTR | transthyretin | 0.107 | ||
| A2M | alpha-2-macroglobulin | 0.101 | ||
| TSC22D1 | TSC22 domain family, member 1 | 0.098 | ||
| C2 | complement component 2 | 0.094 | ||
| C1QB | complement component 1, q subcomponent, B chain | 0.087 | ||
| LCAT | lecithin-cholesterol acyltransferase | 0.064 | ||
| RARRES2 | retinoic acid receptor responder (tazarotene induced) 2 | 0.064 | ||
| APOD | apolipoprotein D | 0.062 | ||
| TMEM176A | transmembrane protein 176A | 0.056 | ||
| FN1 | fibronectin 1 | 0.053 | ||
| CYP2C8 | cytochrome P450, family 2, subfamily C, polypeptide 8 | 0.050 | ||
| LRP1 | low density lipoprotein receptor-related protein 1 | 0.045 | ||
| CP | ceruloplasmin (ferroxidase) | 0.037 | ||
| C4B | complement component 4B (Chido blood group) | 0.037 | ||
| C7 | complement component 7 | 0.036 | ||
| PLG | plasminogen | 0.034 | ||
| SERPINF1 | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 | 0.032 | Human | |
| CFHR1 | complement factor H-related 1 | 0.031 | ||
| PTGDS | prostaglandin D2 synthase 21kDa (brain) | 0.029 | ||
| CYP27A1 | cytochrome P450, family 27, subfamily A, polypeptide 1 | 0.029 | ||
| RARRES1 | retinoic acid receptor responder (tazarotene induced) 1 | 0.028 | ||
| IFITM2 | interferon induced transmembrane protein 2 (1-8D) | 0.028 | ||
| DCN | decorin | 0.026 | ||
| ISLR | immunoglobulin superfamily containing leucine-rich repeat | 0.023 | ||
| ECSIT | ECSIT homolog (Drosophila) | 0.020 | ||
| TMEM176B | transmembrane protein 176B | 0.019 | ||
| APP | amyloid beta (A4) precursor protein | 0.018 | ||
| HSD11B1 | hydroxysteroid (11-beta) dehydrogenase 1 | 0.018 | ||
| C1QC | complement component 1, q subcomponent, C chain | 0.018 | ||
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.018 | ||
| TCN2 | transcobalamin II | 0.018 | ||
| IFITM3 | interferon induced transmembrane protein 3 (1-8U) | 0.017 | ||
| CFD | complement factor D (adipsin) | 0.017 | ||
| PRAM1 | PML-RARA regulated adaptor molecule 1 | 0.016 | ||
| GEM | GTP binding protein overexpressed in skeletal muscle | 0.016 | ||
| CHI3L1 | chitinase 3-like 1 (cartilage glycoprotein-39) | 0.014 | ||
| ALB | albumin | 0.014 | ||
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.014 | ||
| PPAP2B | phosphatidic acid phosphatase type 2B | 0.014 | ||
| C6 | complement component 6 | 0.013 | ||
| CD14 | CD14 molecule | 0.013 | ||
| FMOD | fibromodulin | 0.013 | ||
| DPT | dermatopontin | 0.012 | ||
| CYP2C18 | cytochrome P450, family 2, subfamily C, polypeptide 18 | 0.011 | ||
| HTRA1 | HtrA serine peptidase 1 | 0.011 | ||
| APOL3 | apolipoprotein L, 3 | 0.011 | ||
| RGL1 | ral guanine nucleotide dissociation stimulator-like 1 | 0.011 | ||
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | 0.011 | ||
| CLU | clusterin | 0.011 | ||
| CD74 | CD74 molecule, major histocompatibility complex, class II invariant chain | 0.010 | ||
| CTSK | cathepsin K | 0.010 |