IMP

Process View

Homo sapiens

28 genes annotated in human

Multi-species View

cholesterol efflux

GO:0033344

The directed movement of cholesterol, cholest-5-en-3-beta-ol, out of a cell or organelle.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "cholesterol efflux"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "cholesterol efflux" (in gray)

Name	Description	Probability	Func Analog Organism
REL	v-rel reticuloendotheliosis viral oncogene homolog (avian)	0.959
ALB	albumin	0.950
NFKBIB	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta	0.757	Human
APOA1	apolipoprotein A-I	0.746
C1QA	complement component 1, q subcomponent, A chain	0.612	Human
RELB	v-rel reticuloendotheliosis viral oncogene homolog B	0.527
IRAK2	interleukin-1 receptor-associated kinase 2	0.456
MED15	mediator complex subunit 15	0.443
APOE	apolipoprotein E	0.410
TNIP2	TNFAIP3 interacting protein 2	0.390
ABCA1	ATP-binding cassette, sub-family A (ABC1), member 1	0.286
APOC1	apolipoprotein C-I	0.212
RRAGC	Ras-related GTP binding C	0.211
C1QB	complement component 1, q subcomponent, B chain	0.179	Human
STX12	syntaxin 12	0.177
SNTB2	syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2)	0.176
HP	haptoglobin	0.169
APBB1	amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)	0.129
PELI3	pellino homolog 3 (Drosophila)	0.115
SMO	smoothened homolog (Drosophila)	0.112
NFKBIA	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha	0.085
NFKB2	nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)	0.073
RRAGA	Ras-related GTP binding A	0.065
RELA	v-rel reticuloendotheliosis viral oncogene homolog A (avian)	0.061
C1QC	complement component 1, q subcomponent, C chain	0.057	Human
APOA2	apolipoprotein A-II	0.055
NFKBIE	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon	0.051	Human
NCOA1	nuclear receptor coactivator 1	0.049
C7orf59	chromosome 7 open reading frame 59	0.048
LSS	lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)	0.045
SMPD1	sphingomyelin phosphodiesterase 1, acid lysosomal	0.044
TIRAP	toll-interleukin 1 receptor (TIR) domain containing adaptor protein	0.044
SNX3	sorting nexin 3	0.039
CREBBP	CREB binding protein	0.039
APOC2	apolipoprotein C-II	0.039
NSF	N-ethylmaleimide-sensitive factor	0.038
A2M	alpha-2-macroglobulin	0.038
MSTO1	misato homolog 1 (Drosophila)	0.038
AHSG	alpha-2-HS-glycoprotein	0.036
LCAT	lecithin-cholesterol acyltransferase	0.035
APOB	apolipoprotein B (including Ag(x) antigen)	0.033	Mouse
CACNA1A	calcium channel, voltage-dependent, P/Q type, alpha 1A subunit	0.032
ANXA4	annexin A4	0.030
TRIM11	tripartite motif containing 11	0.029
DHCR7	7-dehydrocholesterol reductase	0.029
VAMP4	vesicle-associated membrane protein 4	0.026
FOXO3	forkhead box O3	0.025
SCD	stearoyl-CoA desaturase (delta-9-desaturase)	0.025
LDLR	low density lipoprotein receptor	0.022
FCN2	ficolin (collagen/fibrinogen domain containing lectin) 2 (hucolin)	0.022
IKBKB	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta	0.021
GPNMB	glycoprotein (transmembrane) nmb	0.021
OSTM1	osteopetrosis associated transmembrane protein 1	0.020
TTR	transthyretin	0.019
INSIG1	insulin induced gene 1	0.019
SIGLEC1	sialic acid binding Ig-like lectin 1, sialoadhesin	0.019
MBL2	mannose-binding lectin (protein C) 2, soluble	0.019
APOC3	apolipoprotein C-III	0.018
VAMP8	vesicle-associated membrane protein 8 (endobrevin)	0.018
CHUK	conserved helix-loop-helix ubiquitous kinase	0.017
ASAH1	N-acylsphingosine amidohydrolase (acid ceramidase) 1	0.017
PLTP	phospholipid transfer protein	0.016
TREM2	triggering receptor expressed on myeloid cells 2	0.015
NFKB1	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1	0.015
FASN	fatty acid synthase	0.015
CCPG1	cell cycle progression 1	0.014
SREBF1	sterol regulatory element binding transcription factor 1	0.014	Human
LAMP2	lysosomal-associated membrane protein 2	0.014
SOCS3	suppressor of cytokine signaling 3	0.014
PRCP	prolylcarboxypeptidase (angiotensinase C)	0.014
ATP6V1B2	ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B2	0.013
HEXB	hexosaminidase B (beta polypeptide)	0.013
MVD	mevalonate (diphospho) decarboxylase	0.013
CREBL2	cAMP responsive element binding protein-like 2	0.013
LIPC	lipase, hepatic	0.013
STX6	syntaxin 6	0.013
ARL6IP5	ADP-ribosylation-like factor 6 interacting protein 5	0.013
CRP	C-reactive protein, pentraxin-related	0.012
LAMTOR3	late endosomal/lysosomal adaptor, MAPK and MTOR activator 3	0.012
KAT2B	K(lysine) acetyltransferase 2B	0.012
DUSP23	dual specificity phosphatase 23	0.012
RRAGD	Ras-related GTP binding D	0.012
CSTB	cystatin B (stefin B)	0.012
PDCD4	programmed cell death 4 (neoplastic transformation inhibitor)	0.012
C4B	complement component 4B (Chido blood group)	0.012
HPD	4-hydroxyphenylpyruvate dioxygenase	0.011
FADS1	fatty acid desaturase 1	0.011
GPLD1	glycosylphosphatidylinositol specific phospholipase D1	0.011
SWAP70	SWAP switching B-cell complex 70kDa subunit	0.011
SLCO2B1	solute carrier organic anion transporter family, member 2B1	0.011
KAT5	K(lysine) acetyltransferase 5	0.011
SCARB1	scavenger receptor class B, member 1	0.011	Mouse
BRI3	brain protein I3	0.011
GPR137B	G protein-coupled receptor 137B	0.011
RAD52	RAD52 homolog (S. cerevisiae)	0.011
RRP8	ribosomal RNA processing 8, methyltransferase, homolog (yeast)	0.010
UBL3	ubiquitin-like 3	0.010
MFSD1	major facilitator superfamily domain containing 1	0.010
MVK	mevalonate kinase	0.010
ACP5	acid phosphatase 5, tartrate resistant	0.010
PCK1	phosphoenolpyruvate carboxykinase 1 (soluble)	0.010
CALCR	calcitonin receptor	0.010
MARCO	macrophage receptor with collagenous structure	0.010