IMP
Process View
er associated misfolded protein catabolic process
The chemical reactions and pathways resulting in the breakdown of misfolded proteins transported from the endoplasmic reticulum and targeted to cytoplasmic proteasomes for degradation.
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In addition to gene-name show these genes:
Click on a gene's description to view its network relationships with genes known to be involved in "er associated misfolded protein catabolic process"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| VCP | valosin containing protein | 1.000 | Yeast Worm | |
| NPLOC4 | nuclear protein localization 4 homolog (S. cerevisiae) | 0.798 | Yeast | |
| UFD1L | ubiquitin fusion degradation 1 like (yeast) | 0.575 | Worm | |
| NSFL1C | NSFL1 (p97) cofactor (p47) | 0.199 | ||
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | 0.058 | ||
| PSMD4 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 4 | 0.053 | ||
| PSMC1 | proteasome (prosome, macropain) 26S subunit, ATPase, 1 | 0.045 | ||
| UBE4B | ubiquitination factor E4B (UFD2 homolog, yeast) | 0.044 | ||
| AMFR | autocrine motility factor receptor | 0.039 | ||
| UBXN2A | UBX domain protein 2A | 0.037 | ||
| ATXN3 | ataxin 3 | 0.037 | ||
| PSMA6 | proteasome (prosome, macropain) subunit, alpha type, 6 | 0.029 | ||
| TRAF6 | TNF receptor-associated factor 6 | 0.025 | ||
| DERL1 | Der1-like domain family, member 1 | 0.025 | ||
| PSMB7 | proteasome (prosome, macropain) subunit, beta type, 7 | 0.023 | ||
| PSMC4 | proteasome (prosome, macropain) 26S subunit, ATPase, 4 | 0.022 | ||
| PSMD13 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 13 | 0.022 | ||
| PSMB1 | proteasome (prosome, macropain) subunit, beta type, 1 | 0.020 | ||
| SYVN1 | synovial apoptosis inhibitor 1, synoviolin | 0.020 | ||
| ASPSCR1 | alveolar soft part sarcoma chromosome region, candidate 1 | 0.019 | ||
| UBE2E3 | ubiquitin-conjugating enzyme E2E 3 (UBC4/5 homolog, yeast) | 0.018 | ||
| PSMD1 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 1 | 0.017 | ||
| PSMC5 | proteasome (prosome, macropain) 26S subunit, ATPase, 5 | 0.014 | ||
| C20orf24 | chromosome 20 open reading frame 24 | 0.013 | ||
| PSMD7 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 7 | 0.012 | ||
| PSMA1 | proteasome (prosome, macropain) subunit, alpha type, 1 | 0.012 | ||
| SELS | selenoprotein S | 0.011 |