IMP
Process View
heparan sulfate proteoglycan metabolic process
The chemical reactions and pathways involving any proteoglycan containing heparan sulfate, any member of a group of glycosaminoglycans that have repeat units consisting of alternating alpha-(1->4)-linked hexuronic acid and glucosamine residues, the former being a mixture of sulfated and nonsulfated D-glucuronic and L-iduronic acids, and the latter being either sulfated or acetylated on its amino group as well as sulfated on one of its hydroxyl groups.
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Click on a gene's description to view its network relationships with genes known to be involved in "heparan sulfate proteoglycan metabolic process"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.969 | ||
| CTNNBIP1 | catenin, beta interacting protein 1 | 0.500 | ||
| TCF4 | transcription factor 4 | 0.271 | ||
| PSEN1 | presenilin 1 | 0.154 | ||
| CDH1 | cadherin 1, type 1, E-cadherin (epithelial) | 0.148 | ||
| GLIS2 | GLIS family zinc finger 2 | 0.096 | ||
| BTRC | beta-transducin repeat containing | 0.075 | ||
| APC | adenomatous polyposis coli | 0.059 | ||
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.046 | ||
| TLE1 | transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) | 0.042 | ||
| CNTF | ciliary neurotrophic factor | 0.035 | ||
| CDH2 | cadherin 2, type 1, N-cadherin (neuronal) | 0.031 | ||
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | 0.028 | ||
| EMD | emerin | 0.022 | ||
| JUP | junction plakoglobin | 0.019 | Human | |
| AR | androgen receptor | 0.019 | ||
| TNIK | TRAF2 and NCK interacting kinase | 0.017 | ||
| HIC1 | hypermethylated in cancer 1 | 0.016 | ||
| IGF2R | insulin-like growth factor 2 receptor | 0.016 | ||
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.015 | ||
| ATP6AP2 | ATPase, H+ transporting, lysosomal accessory protein 2 | 0.015 | ||
| PKP4 | plakophilin 4 | 0.014 | ||
| NCSTN | nicastrin | 0.014 | ||
| MFSD1 | major facilitator superfamily domain containing 1 | 0.013 | ||
| HEXB | hexosaminidase B (beta polypeptide) | 0.012 | ||
| YAP1 | Yes-associated protein 1 | 0.012 | ||
| AXIN1 | axin 1 | 0.011 | ||
| TPP1 | tripeptidyl peptidase I | 0.011 | ||
| GSK3B | glycogen synthase kinase 3 beta | 0.010 |