IMP
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chondroitin sulfate proteoglycan metabolic process
The chemical reactions and pathways involving chondroitin sulfate proteoglycan, any glycoprotein whose glycosaminoglycan units are chondroitin sulfate. Chondroitin sulfates are a group of 10-60 kDa glycosaminoglycans, widely distributed in cartilage and other mammalian connective tissues; the repeat units consist of beta-(1,4)-linked D-glucuronyl beta-(1,3)-N-acetyl-D-galactosamine sulfate.
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| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| ELN | elastin | 0.703 | ||
| COL6A1 | collagen, type VI, alpha 1 | 0.354 | ||
| LUM | lumican | 0.256 | ||
| COL1A1 | collagen, type I, alpha 1 | 0.132 | ||
| BNIP2 | BCL2/adenovirus E1B 19kDa interacting protein 2 | 0.111 | ||
| DPT | dermatopontin | 0.107 | ||
| PCOLCE | procollagen C-endopeptidase enhancer | 0.103 | ||
| COL14A1 | collagen, type XIV, alpha 1 | 0.092 | ||
| COL1A2 | collagen, type I, alpha 2 | 0.066 | ||
| ARFGAP3 | ADP-ribosylation factor GTPase activating protein 3 | 0.065 | ||
| LAMA2 | laminin, alpha 2 | 0.053 | ||
| MXRA5 | matrix-remodelling associated 5 | 0.050 | ||
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.049 | ||
| OMD | osteomodulin | 0.044 | ||
| MFAP2 | microfibrillar-associated protein 2 | 0.043 | ||
| ISLR | immunoglobulin superfamily containing leucine-rich repeat | 0.042 | ||
| OLFML3 | olfactomedin-like 3 | 0.040 | ||
| MRC2 | mannose receptor, C type 2 | 0.038 | ||
| COL6A2 | collagen, type VI, alpha 2 | 0.037 | ||
| KLF10 | Kruppel-like factor 10 | 0.037 | ||
| ASPN | asporin | 0.033 | ||
| CXCL12 | chemokine (C-X-C motif) ligand 12 | 0.032 | ||
| LTBP2 | latent transforming growth factor beta binding protein 2 | 0.032 | ||
| CHSY1 | chondroitin sulfate synthase 1 | 0.031 | ||
| GLT8D2 | glycosyltransferase 8 domain containing 2 | 0.030 | ||
| FBN1 | fibrillin 1 | 0.030 | ||
| ECM2 | extracellular matrix protein 2, female organ and adipocyte specific | 0.025 | ||
| MAN1B1 | mannosidase, alpha, class 1B, member 1 | 0.025 | ||
| LOX | lysyl oxidase | 0.025 | ||
| MGP | matrix Gla protein | 0.023 | ||
| FMOD | fibromodulin | 0.023 | ||
| FBLN2 | fibulin 2 | 0.021 | ||
| C1S | complement component 1, s subcomponent | 0.021 | ||
| PDGFRB | platelet-derived growth factor receptor, beta polypeptide | 0.021 | ||
| ZNF267 | zinc finger protein 267 | 0.020 | ||
| SEC24A | SEC24 family, member A (S. cerevisiae) | 0.020 | ||
| PTGDS | prostaglandin D2 synthase 21kDa (brain) | 0.020 | ||
| FNDC3B | fibronectin type III domain containing 3B | 0.018 | ||
| CSGALNACT2 | chondroitin sulfate N-acetylgalactosaminyltransferase 2 | 0.018 | ||
| PARK2 | parkinson protein 2, E3 ubiquitin protein ligase (parkin) | 0.017 | ||
| ADH1B | alcohol dehydrogenase 1B (class I), beta polypeptide | 0.017 | ||
| MFAP5 | microfibrillar associated protein 5 | 0.017 | ||
| MFAP4 | microfibrillar-associated protein 4 | 0.017 | ||
| FAP | fibroblast activation protein, alpha | 0.017 | ||
| GPC1 | glypican 1 | 0.016 | ||
| C1R | complement component 1, r subcomponent | 0.016 | ||
| COL6A3 | collagen, type VI, alpha 3 | 0.016 | ||
| OLFML2B | olfactomedin-like 2B | 0.015 | ||
| VCAN | versican | 0.015 | ||
| B4GALT7 | xylosylprotein beta 1,4-galactosyltransferase, polypeptide 7 (galactosyltransferase I) | 0.015 | ||
| ZEB2 | zinc finger E-box binding homeobox 2 | 0.015 | ||
| PRRX1 | paired related homeobox 1 | 0.014 | ||
| RCN3 | reticulocalbin 3, EF-hand calcium binding domain | 0.014 | ||
| CTSK | cathepsin K | 0.013 | ||
| PLXDC1 | plexin domain containing 1 | 0.013 | ||
| IGFBP4 | insulin-like growth factor binding protein 4 | 0.013 | ||
| COL4A2 | collagen, type IV, alpha 2 | 0.013 | ||
| SULF1 | sulfatase 1 | 0.013 | ||
| YIPF2 | Yip1 domain family, member 2 | 0.012 | ||
| CILP | cartilage intermediate layer protein, nucleotide pyrophosphohydrolase | 0.012 | ||
| PTGIS | prostaglandin I2 (prostacyclin) synthase | 0.012 | ||
| GJA4 | gap junction protein, alpha 4, 37kDa | 0.011 | ||
| AEBP1 | AE binding protein 1 | 0.011 | ||
| FAM3A | family with sequence similarity 3, member A | 0.011 | ||
| ITGBL1 | integrin, beta-like 1 (with EGF-like repeat domains) | 0.011 | ||
| THBS2 | thrombospondin 2 | 0.011 | ||
| EDNRA | endothelin receptor type A | 0.011 | ||
| FBLN5 | fibulin 5 | 0.011 | ||
| C7 | complement component 7 | 0.011 | ||
| LOXL1 | lysyl oxidase-like 1 | 0.011 | ||
| COMP | cartilage oligomeric matrix protein | 0.010 | ||
| ACSL4 | acyl-CoA synthetase long-chain family member 4 | 0.010 | ||
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.010 | ||
| FBLN1 | fibulin 1 | 0.010 |