IMP
Process View
artery smooth muscle contraction
A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the artery. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The artery is a vessel carrying blood away from the heart.
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In addition to gene-name show these genes:
Click on a gene's description to view its network relationships with genes known to be involved in "artery smooth muscle contraction"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| UBQLN4 | ubiquilin 4 | 0.478 | ||
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | 0.410 | ||
| EDN1 | endothelin 1 | 0.313 | ||
| PIP4K2B | phosphatidylinositol-5-phosphate 4-kinase, type II, beta | 0.210 | ||
| GKAP1 | G kinase anchoring protein 1 | 0.166 | ||
| CAV1 | caveolin 1, caveolae protein, 22kDa | 0.139 | ||
| SPARCL1 | SPARC-like 1 (hevin) | 0.118 | ||
| CEND1 | cell cycle exit and neuronal differentiation 1 | 0.108 | ||
| MLLT6 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 6 | 0.096 | ||
| EDNRA | endothelin receptor type A | 0.093 | ||
| DCN | decorin | 0.085 | ||
| PTN | pleiotrophin | 0.081 | ||
| PAX2 | paired box 2 | 0.075 | ||
| RGS4 | regulator of G-protein signaling 4 | 0.070 | ||
| CAV2 | caveolin 2 | 0.065 | ||
| COL4A1 | collagen, type IV, alpha 1 | 0.057 | ||
| ITPRIPL1 | inositol 1,4,5-trisphosphate receptor interacting protein-like 1 | 0.052 | ||
| PCDH17 | protocadherin 17 | 0.051 | ||
| GABRD | gamma-aminobutyric acid (GABA) A receptor, delta | 0.048 | ||
| EGR4 | early growth response 4 | 0.044 | ||
| CCDC134 | coiled-coil domain containing 134 | 0.042 | ||
| RUNX1T1 | runt-related transcription factor 1; translocated to, 1 (cyclin D-related) | 0.041 | ||
| COL8A1 | collagen, type VIII, alpha 1 | 0.038 | ||
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | 0.037 | ||
| ZNF205 | zinc finger protein 205 | 0.037 | ||
| SLC1A6 | solute carrier family 1 (high affinity aspartate/glutamate transporter), member 6 | 0.036 | ||
| ERG | v-ets erythroblastosis virus E26 oncogene homolog (avian) | 0.036 | ||
| AGTR1 | angiotensin II receptor, type 1 | 0.035 | ||
| SCAF1 | SR-related CTD-associated factor 1 | 0.035 | ||
| HK2 | hexokinase 2 | 0.034 | ||
| SFRP1 | secreted frizzled-related protein 1 | 0.034 | ||
| ZG16B | zymogen granule protein 16 homolog B (rat) | 0.034 | ||
| ANKRD13D | ankyrin repeat domain 13 family, member D | 0.033 | ||
| ELTD1 | EGF, latrophilin and seven transmembrane domain containing 1 | 0.033 | ||
| SCG2 | secretogranin II | 0.032 | ||
| CDH5 | cadherin 5, type 2 (vascular endothelium) | 0.031 | ||
| SPAG8 | sperm associated antigen 8 | 0.031 | ||
| NPPA | natriuretic peptide A | 0.031 | ||
| ERP27 | endoplasmic reticulum protein 27 | 0.031 | ||
| SCG5 | secretogranin V (7B2 protein) | 0.030 | ||
| ACCN1 | amiloride-sensitive cation channel 1, neuronal | 0.030 | ||
| PICK1 | protein interacting with PRKCA 1 | 0.029 | ||
| FKBP2 | FK506 binding protein 2, 13kDa | 0.029 | ||
| CDH6 | cadherin 6, type 2, K-cadherin (fetal kidney) | 0.027 | ||
| MCHR1 | melanin-concentrating hormone receptor 1 | 0.027 | ||
| ADAM33 | ADAM metallopeptidase domain 33 | 0.027 | ||
| LPPR4 | lipid phosphate phosphatase-related protein type 4 | 0.027 | ||
| NPHP1 | nephronophthisis 1 (juvenile) | 0.026 | ||
| EDNRB | endothelin receptor type B | 0.026 | Human | |
| CCDC14 | coiled-coil domain containing 14 | 0.026 | ||
| HRK | harakiri, BCL2 interacting protein (contains only BH3 domain) | 0.026 | ||
| VGF | VGF nerve growth factor inducible | 0.025 | ||
| ASPN | asporin | 0.024 | ||
| NELL1 | NEL-like 1 (chicken) | 0.024 | ||
| NID1 | nidogen 1 | 0.024 | ||
| NOTCH2NL | notch 2 N-terminal like | 0.024 | ||
| ENPEP | glutamyl aminopeptidase (aminopeptidase A) | 0.024 | ||
| VIP | vasoactive intestinal peptide | 0.022 | ||
| SMCR7 | Smith-Magenis syndrome chromosome region, candidate 7 | 0.022 | ||
| KLHDC5 | kelch domain containing 5 | 0.022 | ||
| ATP2B3 | ATPase, Ca++ transporting, plasma membrane 3 | 0.022 | ||
| WNT7A | wingless-type MMTV integration site family, member 7A | 0.022 | ||
| CDHR5 | cadherin-related family member 5 | 0.021 | ||
| JPH3 | junctophilin 3 | 0.021 | ||
| PCDH8 | protocadherin 8 | 0.020 | ||
| FABP7 | fatty acid binding protein 7, brain | 0.020 | ||
| CALY | calcyon neuron-specific vesicular protein | 0.020 | ||
| LASS1 | LAG1 homolog, ceramide synthase 1 | 0.020 | ||
| NTRK3 | neurotrophic tyrosine kinase, receptor, type 3 | 0.020 | ||
| THY1 | Thy-1 cell surface antigen | 0.020 | ||
| ABCC8 | ATP-binding cassette, sub-family C (CFTR/MRP), member 8 | 0.019 | ||
| FBXL7 | F-box and leucine-rich repeat protein 7 | 0.019 | ||
| CD93 | CD93 molecule | 0.019 | ||
| LBX1 | ladybird homeobox 1 | 0.019 | ||
| KRT14 | keratin 14 | 0.019 | ||
| NPY | neuropeptide Y | 0.019 | ||
| ELF5 | E74-like factor 5 (ets domain transcription factor) | 0.019 | ||
| NPY2R | neuropeptide Y receptor Y2 | 0.018 | ||
| KCNQ2 | potassium voltage-gated channel, KQT-like subfamily, member 2 | 0.018 | ||
| TRIL | TLR4 interactor with leucine-rich repeats | 0.018 | ||
| ECM2 | extracellular matrix protein 2, female organ and adipocyte specific | 0.018 | ||
| ZG16 | zymogen granule protein 16 homolog (rat) | 0.018 | ||
| RGS5 | regulator of G-protein signaling 5 | 0.018 | ||
| PRRX1 | paired related homeobox 1 | 0.018 | ||
| KDR | kinase insert domain receptor (a type III receptor tyrosine kinase) | 0.017 | ||
| CNTFR | ciliary neurotrophic factor receptor | 0.017 | ||
| HAVCR1 | hepatitis A virus cellular receptor 1 | 0.017 | ||
| FGF18 | fibroblast growth factor 18 | 0.017 | ||
| IL33 | interleukin 33 | 0.017 | ||
| IGF1 | insulin-like growth factor 1 (somatomedin C) | 0.016 | ||
| LRRN2 | leucine rich repeat neuronal 2 | 0.016 | ||
| TM4SF1 | transmembrane 4 L six family member 1 | 0.016 | ||
| KCNJ8 | potassium inwardly-rectifying channel, subfamily J, member 8 | 0.016 | ||
| COL4A3 | collagen, type IV, alpha 3 (Goodpasture antigen) | 0.016 | ||
| NKX2-8 | NK2 homeobox 8 | 0.016 | ||
| GJA1 | gap junction protein, alpha 1, 43kDa | 0.015 | ||
| HCN2 | hyperpolarization activated cyclic nucleotide-gated potassium channel 2 | 0.015 | ||
| KIF1A | kinesin family member 1A | 0.015 | ||
| CALCA | calcitonin-related polypeptide alpha | 0.015 | ||
| GPX7 | glutathione peroxidase 7 | 0.015 | ||
| EMCN | endomucin | 0.015 | ||
| SOX17 | SRY (sex determining region Y)-box 17 | 0.015 | ||
| TSPAN7 | tetraspanin 7 | 0.015 | ||
| TRPC6 | transient receptor potential cation channel, subfamily C, member 6 | 0.015 | ||
| SULF1 | sulfatase 1 | 0.014 | ||
| AGT | angiotensinogen (serpin peptidase inhibitor, clade A, member 8) | 0.014 | Rat | |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | 0.014 | ||
| PI15 | peptidase inhibitor 15 | 0.014 | ||
| FAM5B | family with sequence similarity 5, member B | 0.014 | ||
| CDK5R2 | cyclin-dependent kinase 5, regulatory subunit 2 (p39) | 0.014 | ||
| FGF8 | fibroblast growth factor 8 (androgen-induced) | 0.014 | ||
| CCKBR | cholecystokinin B receptor | 0.014 | ||
| S100G | S100 calcium binding protein G | 0.014 | ||
| SPP1 | secreted phosphoprotein 1 | 0.014 | ||
| SLC6A4 | solute carrier family 6 (neurotransmitter transporter, serotonin), member 4 | 0.014 | ||
| LHX1 | LIM homeobox 1 | 0.014 | ||
| COL3A1 | collagen, type III, alpha 1 | 0.014 | ||
| LUM | lumican | 0.013 | ||
| MAGEL2 | MAGE-like 2 | 0.013 | ||
| CHGB | chromogranin B (secretogranin 1) | 0.013 | ||
| PRKCG | protein kinase C, gamma | 0.013 | ||
| NID2 | nidogen 2 (osteonidogen) | 0.013 | ||
| PDGFB | platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog) | 0.013 | ||
| GRP | gastrin-releasing peptide | 0.013 | ||
| PYY | peptide YY | 0.013 | ||
| SV2C | synaptic vesicle glycoprotein 2C | 0.013 | ||
| KCNA5 | potassium voltage-gated channel, shaker-related subfamily, member 5 | 0.013 | ||
| SERPINI2 | serpin peptidase inhibitor, clade I (pancpin), member 2 | 0.013 | ||
| CRLF1 | cytokine receptor-like factor 1 | 0.013 | ||
| TMEM59L | transmembrane protein 59-like | 0.013 | ||
| MASP1 | mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor) | 0.012 | ||
| FNDC1 | fibronectin type III domain containing 1 | 0.012 | ||
| TRIM32 | tripartite motif containing 32 | 0.012 | ||
| COL2A1 | collagen, type II, alpha 1 | 0.012 | ||
| GABRB3 | gamma-aminobutyric acid (GABA) A receptor, beta 3 | 0.012 | ||
| ATP2B2 | ATPase, Ca++ transporting, plasma membrane 2 | 0.012 | ||
| OPRK1 | opioid receptor, kappa 1 | 0.012 | ||
| RND3 | Rho family GTPase 3 | 0.012 | ||
| ID4 | inhibitor of DNA binding 4, dominant negative helix-loop-helix protein | 0.012 | ||
| OCA2 | oculocutaneous albinism II | 0.012 | ||
| EMX2 | empty spiracles homeobox 2 | 0.012 | ||
| TGFB3 | transforming growth factor, beta 3 | 0.012 | ||
| APLNR | apelin receptor | 0.012 | ||
| CDH8 | cadherin 8, type 2 | 0.012 | ||
| TH | tyrosine hydroxylase | 0.012 | ||
| NNAT | neuronatin | 0.012 | ||
| WIF1 | WNT inhibitory factor 1 | 0.012 | ||
| PAX8 | paired box 8 | 0.012 | ||
| NOVA2 | neuro-oncological ventral antigen 2 | 0.012 | ||
| OPCML | opioid binding protein/cell adhesion molecule-like | 0.012 | ||
| SNAI2 | snail homolog 2 (Drosophila) | 0.012 | ||
| TRIB2 | tribbles homolog 2 (Drosophila) | 0.012 | ||
| SNAP91 | synaptosomal-associated protein, 91kDa homolog (mouse) | 0.012 | ||
| EFNA2 | ephrin-A2 | 0.012 | ||
| TFF1 | trefoil factor 1 | 0.011 | ||
| GRIK1 | glutamate receptor, ionotropic, kainate 1 | 0.011 | ||
| DSPP | dentin sialophosphoprotein | 0.011 | ||
| GYG2 | glycogenin 2 | 0.011 | ||
| IHH | Indian hedgehog | 0.011 | ||
| SCRG1 | stimulator of chondrogenesis 1 | 0.011 | ||
| ZNF536 | zinc finger protein 536 | 0.011 | ||
| GFAP | glial fibrillary acidic protein | 0.011 | ||
| ABCC9 | ATP-binding cassette, sub-family C (CFTR/MRP), member 9 | 0.011 | ||
| MYO1A | myosin IA | 0.011 | ||
| PDE6A | phosphodiesterase 6A, cGMP-specific, rod, alpha | 0.011 | ||
| BMP2 | bone morphogenetic protein 2 | 0.011 | ||
| NTRK2 | neurotrophic tyrosine kinase, receptor, type 2 | 0.011 | ||
| TAC1 | tachykinin, precursor 1 | 0.011 | ||
| IGSF1 | immunoglobulin superfamily, member 1 | 0.011 | ||
| TTYH1 | tweety homolog 1 (Drosophila) | 0.011 | ||
| CNTN1 | contactin 1 | 0.011 | ||
| GRIK4 | glutamate receptor, ionotropic, kainate 4 | 0.011 | ||
| CHRNB2 | cholinergic receptor, nicotinic, beta 2 (neuronal) | 0.011 | ||
| MAOB | monoamine oxidase B | 0.011 | ||
| RET | ret proto-oncogene | 0.011 | ||
| CADM4 | cell adhesion molecule 4 | 0.011 | ||
| S100A1 | S100 calcium binding protein A1 | 0.011 | ||
| MDK | midkine (neurite growth-promoting factor 2) | 0.010 | ||
| ARR3 | arrestin 3, retinal (X-arrestin) | 0.010 | ||
| SEPT4 | septin 4 | 0.010 | ||
| PCP4 | Purkinje cell protein 4 | 0.010 | ||
| PTPRR | protein tyrosine phosphatase, receptor type, R | 0.010 | ||
| FZD7 | frizzled homolog 7 (Drosophila) | 0.010 | ||
| RHBDL1 | rhomboid, veinlet-like 1 (Drosophila) | 0.010 | ||
| FAM48A | family with sequence similarity 48, member A | 0.010 | ||
| ACTL6B | actin-like 6B | 0.010 | ||
| SSTR2 | somatostatin receptor 2 | 0.010 | ||
| USH1C | Usher syndrome 1C (autosomal recessive, severe) | 0.010 | ||
| SCMH1 | sex comb on midleg homolog 1 (Drosophila) | 0.010 | ||
| TMEM90B | transmembrane protein 90B | 0.010 | ||
| HOXD10 | homeobox D10 | 0.010 |