IMP

Process View

Homo sapiens

11 genes annotated in human

Multi-species View

protein localization to lysosome

GO:0061462

A process in which a protein is transported to, or maintained in, a location within a lysosome.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "protein localization to lysosome"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "protein localization to lysosome" (in gray)

Name	Description	Probability	Func Analog Organism
SMURF2	SMAD specific E3 ubiquitin protein ligase 2	0.994	Human
GGA1	golgi-associated, gamma adaptin ear containing, ARF binding protein 1	0.968
IGF2R	insulin-like growth factor 2 receptor	0.865
GGA2	golgi-associated, gamma adaptin ear containing, ARF binding protein 2	0.524
WWP1	WW domain containing E3 ubiquitin protein ligase 1	0.453	Human
ZFYVE9	zinc finger, FYVE domain containing 9	0.426	Human
LAMTOR1	late endosomal/lysosomal adaptor, MAPK and MTOR activator 1	0.390
LAMTOR2	late endosomal/lysosomal adaptor, MAPK and MTOR activator 2	0.252
SORT1	sortilin 1	0.228	Human
SYNRG	synergin, gamma	0.202
RABEP1	rabaptin, RAB GTPase binding effector protein 1	0.145
SMURF1	SMAD specific E3 ubiquitin protein ligase 1	0.139	Human
FBXL15	F-box and leucine-rich repeat protein 15	0.133
SNX9	sorting nexin 9	0.110
DNM2	dynamin 2	0.100
SORL1	sortilin-related receptor, L(DLR class) A repeats containing	0.087
SMAD4	SMAD family member 4	0.080
SPG20	spastic paraplegia 20 (Troyer syndrome)	0.080
ANKRD13A	ankyrin repeat domain 13A	0.080
NEDD4	neural precursor cell expressed, developmentally down-regulated 4	0.077
WWP2	WW domain containing E3 ubiquitin protein ligase 2	0.060	Human
GGA3	golgi-associated, gamma adaptin ear containing, ARF binding protein 3	0.055
CAPRIN2	caprin family member 2	0.041
ABCF3	ATP-binding cassette, sub-family F (GCN20), member 3	0.039
RNF11	ring finger protein 11	0.033
STAM2	signal transducing adaptor molecule (SH3 domain and ITAM motif) 2	0.033
DAB2	disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)	0.029
NEDD9	neural precursor cell expressed, developmentally down-regulated 9	0.028
RAB6A	RAB6A, member RAS oncogene family	0.027
TRAF4	TNF receptor-associated factor 4	0.025
CCDC127	coiled-coil domain containing 127	0.023
SMAD5	SMAD family member 5	0.023
EIF1B	eukaryotic translation initiation factor 1B	0.022
CXXC5	CXXC finger protein 5	0.022
PDCD6IP	programmed cell death 6 interacting protein	0.021
POU5F1	POU class 5 homeobox 1	0.020
MON2	MON2 homolog (S. cerevisiae)	0.020
TOM1	target of myb1 (chicken)	0.019
MED15	mediator complex subunit 15	0.018
TFRC	transferrin receptor (p90, CD71)	0.018
ZRANB1	zinc finger, RAN-binding domain containing 1	0.017
RABIF	RAB interacting factor	0.015
RNF168	ring finger protein 168	0.015
SPG21	spastic paraplegia 21 (autosomal recessive, Mast syndrome)	0.014
EPS15	epidermal growth factor receptor pathway substrate 15	0.014
DKK1	dickkopf homolog 1 (Xenopus laevis)	0.014
SNRNP70	small nuclear ribonucleoprotein 70kDa (U1)	0.013
ROCK1	Rho-associated, coiled-coil containing protein kinase 1	0.013
SGK3	serum/glucocorticoid regulated kinase family, member 3	0.013
TAX1BP1	Tax1 (human T-cell leukemia virus type I) binding protein 1	0.012
ITCH	itchy E3 ubiquitin protein ligase homolog (mouse)	0.012	Human
RRAGC	Ras-related GTP binding C	0.011
EEA1	early endosome antigen 1	0.011
DEDD	death effector domain containing	0.011
LRRK2	leucine-rich repeat kinase 2	0.010
UBQLN2	ubiquilin 2	0.010
PHF20L1	PHD finger protein 20-like 1	0.010