IMP

Process View

Homo sapiens

11 genes annotated in human

Multi-species View

protein localization to vacuole

GO:0072665

A process in which a protein is transported to, or maintained at, a location in a vacuole.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "protein localization to vacuole"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "protein localization to vacuole" (in gray)

Name	Description	Probability	Func Analog Organism
SMURF2	SMAD specific E3 ubiquitin protein ligase 2	0.842	Human
GGA1	golgi-associated, gamma adaptin ear containing, ARF binding protein 1	0.766
ATG3	ATG3 autophagy related 3 homolog (S. cerevisiae)	0.360	Yeast
ATG7	ATG7 autophagy related 7 homolog (S. cerevisiae)	0.259	Yeast
RABEP1	rabaptin, RAB GTPase binding effector protein 1	0.191
SNF8	SNF8, ESCRT-II complex subunit, homolog (S. cerevisiae)	0.180	Yeast
GABARAPL2	GABA(A) receptor-associated protein-like 2	0.137
SORT1	sortilin 1	0.094	Human
SLC2A3	solute carrier family 2 (facilitated glucose transporter), member 3	0.093
MAP1LC3B	microtubule-associated protein 1 light chain 3 beta	0.083
GABARAP	GABA(A) receptor-associated protein	0.082
ATG5	ATG5 autophagy related 5 homolog (S. cerevisiae)	0.079
EEA1	early endosome antigen 1	0.066
DNM2	dynamin 2	0.062
PDCD6IP	programmed cell death 6 interacting protein	0.061
ANKRD13A	ankyrin repeat domain 13A	0.056
WWP1	WW domain containing E3 ubiquitin protein ligase 1	0.051	Human
LRRK2	leucine-rich repeat kinase 2	0.049
SQSTM1	sequestosome 1	0.048
LAMTOR2	late endosomal/lysosomal adaptor, MAPK and MTOR activator 2	0.046
SYNRG	synergin, gamma	0.044
LAMTOR1	late endosomal/lysosomal adaptor, MAPK and MTOR activator 1	0.043
ATG12	ATG12 autophagy related 12 homolog (S. cerevisiae)	0.038	Yeast
CHMP4B	chromatin modifying protein 4B	0.034
ELL	elongation factor RNA polymerase II	0.032
ZFYVE9	zinc finger, FYVE domain containing 9	0.031	Human
WWP2	WW domain containing E3 ubiquitin protein ligase 2	0.029	Human
SMURF1	SMAD specific E3 ubiquitin protein ligase 1	0.025	Human
IGF2R	insulin-like growth factor 2 receptor	0.025
SPG21	spastic paraplegia 21 (autosomal recessive, Mast syndrome)	0.025
COG7	component of oligomeric golgi complex 7	0.022
SCNN1B	sodium channel, nonvoltage-gated 1, beta	0.020
FBXL15	F-box and leucine-rich repeat protein 15	0.020
RAB22A	RAB22A, member RAS oncogene family	0.020
ROCK1	Rho-associated, coiled-coil containing protein kinase 1	0.019
NBR1	neighbor of BRCA1 gene 1	0.019
GGA2	golgi-associated, gamma adaptin ear containing, ARF binding protein 2	0.018
SORL1	sortilin-related receptor, L(DLR class) A repeats containing	0.016
ARPC5	actin related protein 2/3 complex, subunit 5, 16kDa	0.015
TAX1BP1	Tax1 (human T-cell leukemia virus type I) binding protein 1	0.015
TMED2	transmembrane emp24 domain trafficking protein 2	0.015
RAB1A	RAB1A, member RAS oncogene family	0.015
OCRL	oculocerebrorenal syndrome of Lowe	0.015
ATG16L1	ATG16 autophagy related 16-like 1 (S. cerevisiae)	0.015
SMAD4	SMAD family member 4	0.014
RHOA	ras homolog gene family, member A	0.013
CALCOCO2	calcium binding and coiled-coil domain 2	0.013
ATG10	ATG10 autophagy related 10 homolog (S. cerevisiae)	0.013
SH3GL2	SH3-domain GRB2-like 2	0.012
SEPT2	septin 2	0.012
ATG4B	ATG4 autophagy related 4 homolog B (S. cerevisiae)	0.012	Yeast
CIZ1	CDKN1A interacting zinc finger protein 1	0.012
SCFD1	sec1 family domain containing 1	0.011
CANX	calnexin	0.011
RABIF	RAB interacting factor	0.011
COG1	component of oligomeric golgi complex 1	0.011
CAPRIN2	caprin family member 2	0.011
SNX9	sorting nexin 9	0.011
PRKAR1A	protein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1)	0.011
CTTN	cortactin	0.010
RAB6A	RAB6A, member RAS oncogene family	0.010
ZRANB1	zinc finger, RAN-binding domain containing 1	0.010