IMP

Process View

Homo sapiens

17 genes annotated in human

intermediate filament cytoskeleton organization

A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising intermediate filaments and their associated proteins.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "intermediate filament cytoskeleton organization"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "intermediate filament cytoskeleton organization" (in gray)

Name	Description	Probability	Func Analog Organism
KRT15	keratin 15	1.000	Human
KRT6B	keratin 6B	0.999	Human Mouse
KRT14	keratin 14	0.988
PKP1	plakophilin 1 (ectodermal dysplasia/skin fragility syndrome)	0.986
KRT19	keratin 19	0.985	Human
ERBB2IP	erbb2 interacting protein	0.978	Worm
KRT18	keratin 18	0.977
UBQLN1	ubiquilin 1	0.963
KRT17	keratin 17	0.961	Human
KRT8	keratin 8	0.960	Human
ITGB4	integrin, beta 4	0.881
APC	adenomatous polyposis coli	0.869
KRT6A	keratin 6A	0.866	Human
EPS15	epidermal growth factor receptor pathway substrate 15	0.849
DTNA	dystrobrevin, alpha	0.846
KRT5	keratin 5	0.785	Human
MTMR12	myotubularin related protein 12	0.733	Human
PAFAH1B1	platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)	0.673
KRT34	keratin 34	0.672	Human
KRT1	keratin 1	0.639	Human
SMAD9	SMAD family member 9	0.604
PSEN1	presenilin 1	0.556
TP63	tumor protein p63	0.550
MTM1	myotubularin 1	0.516
PPP2R2B	protein phosphatase 2, regulatory subunit B, beta	0.446
HSPA8	heat shock 70kDa protein 8	0.364
KRT33B	keratin 33B	0.337	Human
CDH1	cadherin 1, type 1, E-cadherin (epithelial)	0.335
PKP4	plakophilin 4	0.333	Human
SPRR1A	small proline-rich protein 1A	0.316
EXOC8	exocyst complex component 8	0.307
KRT16	keratin 16	0.240	Human Mouse
KRT32	keratin 32	0.238	Human
DSP	desmoplakin	0.226	Mouse
SFN	stratifin	0.188
KRT36	keratin 36	0.188	Human
TOR1A	torsin family 1, member A (torsin A)	0.184
CCDC85B	coiled-coil domain containing 85B	0.180
KRT75	keratin 75	0.178	Human
TRIM29	tripartite motif containing 29	0.170
LAD1	ladinin 1	0.169
PKP2	plakophilin 2	0.160
JUP	junction plakoglobin	0.135
KRT2	keratin 2	0.133	Human
KRT35	keratin 35	0.132	Human
ALB	albumin	0.131
BAG1	BCL2-associated athanogene	0.129
KRT81	keratin 81	0.125	Human
DSG3	desmoglein 3	0.124
PSMD4	proteasome (prosome, macropain) 26S subunit, non-ATPase, 4	0.115
KRT33A	keratin 33A	0.107	Human
SOS1	son of sevenless homolog 1 (Drosophila)	0.104
PHLPP1	PH domain and leucine rich repeat protein phosphatase 1	0.103
KRT6C	keratin 6C	0.102
KRT9	keratin 9	0.097
MARK3	MAP/microtubule affinity-regulating kinase 3	0.096
DMD	dystrophin	0.095
IVL	involucrin	0.087
KRT13	keratin 13	0.077	Human
KIAA0408	KIAA0408	0.076
TJP2	tight junction protein 2 (zona occludens 2)	0.076
SMAD4	SMAD family member 4	0.076
TOR1AIP2	torsin A interacting protein 2	0.075
TEKT4	tektin 4	0.067
SLURP1	secreted LY6/PLAUR domain containing 1	0.066
MTMR9	myotubularin related protein 9	0.065	Human
PTPRJ	protein tyrosine phosphatase, receptor type, J	0.062
KRT4	keratin 4	0.062	Human
KRT31	keratin 31	0.058	Human
KLK10	kallikrein-related peptidase 10	0.057
COL17A1	collagen, type XVII, alpha 1	0.056
SQSTM1	sequestosome 1	0.056
FRMD5	FERM domain containing 5	0.053
KIAA1217	KIAA1217	0.052
KRT38	keratin 38	0.051	Human
SPRR1B	small proline-rich protein 1B	0.049
NUMB	numb homolog (Drosophila)	0.046
VIM	vimentin	0.044	Human Mouse
PSEN2	presenilin 2 (Alzheimer disease 4)	0.044
TRIM63	tripartite motif containing 63	0.043
ELF3	E74-like factor 3 (ets domain transcription factor, epithelial-specific )	0.043
TOR1B	torsin family 1, member B (torsin B)	0.043	Human
MAPK1	mitogen-activated protein kinase 1	0.040
DSG1	desmoglein 1	0.039
ATF7IP	activating transcription factor 7 interacting protein	0.039
KRT37	keratin 37	0.036	Human
KIF5B	kinesin family member 5B	0.031
S100A14	S100 calcium binding protein A14	0.031
GADD45A	growth arrest and DNA-damage-inducible, alpha	0.030
MAP2K1	mitogen-activated protein kinase kinase 1	0.030
RAD23B	RAD23 homolog B (S. cerevisiae)	0.029
SPTBN1	spectrin, beta, non-erythrocytic 1	0.029
DSC3	desmocollin 3	0.028
KRT85	keratin 85	0.025	Human
TJP1	tight junction protein 1 (zona occludens 1)	0.025
EXOC1	exocyst complex component 1	0.024
LOR	loricrin	0.023
MAFG	v-maf musculoaponeurotic fibrosarcoma oncogene homolog G (avian)	0.023
HSPA13	heat shock protein 70kDa family, member 13	0.023
LYPD3	LY6/PLAUR domain containing 3	0.023
TNIK	TRAF2 and NCK interacting kinase	0.023
FAM107A	family with sequence similarity 107, member A	0.022
ALOX12	arachidonate 12-lipoxygenase	0.022
COPS4	COP9 constitutive photomorphogenic homolog subunit 4 (Arabidopsis)	0.022
HDAC11	histone deacetylase 11	0.021
ING5	inhibitor of growth family, member 5	0.021
KRT7	keratin 7	0.021	Human
LY6D	lymphocyte antigen 6 complex, locus D	0.021
RHCG	Rh family, C glycoprotein	0.020
LY6G6C	lymphocyte antigen 6 complex, locus G6C	0.020
APOA1	apolipoprotein A-I	0.020
SPG21	spastic paraplegia 21 (autosomal recessive, Mast syndrome)	0.020
GJB5	gap junction protein, beta 5, 31.1kDa	0.019
RHOD	ras homolog gene family, member D	0.019
TTR	transthyretin	0.018
TRADD	TNFRSF1A-associated via death domain	0.018
SKIL	SKI-like oncogene	0.018
NFATC2	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2	0.018
NEFL	neurofilament, light polypeptide	0.018
CXXC5	CXXC finger protein 5	0.017
KRT23	keratin 23 (histone deacetylase inducible)	0.017	Human
PAX9	paired box 9	0.017
STON2	stonin 2	0.017
DST	dystonin	0.017
PPL	periplakin	0.017
C1orf65	chromosome 1 open reading frame 65	0.017
GJB3	gap junction protein, beta 3, 31kDa	0.016
C10orf10	chromosome 10 open reading frame 10	0.016
SPRR3	small proline-rich protein 3	0.016
CLIP1	CAP-GLY domain containing linker protein 1	0.016
ABLIM1	actin binding LIM protein 1	0.016
PI3	peptidase inhibitor 3, skin-derived	0.016
C16orf70	chromosome 16 open reading frame 70	0.016
ARHGEF7	Rho guanine nucleotide exchange factor (GEF) 7	0.015
TCHH	trichohyalin	0.014
TRIOBP	TRIO and F-actin binding protein	0.014
BAG2	BCL2-associated athanogene 2	0.013
SERPINB5	serpin peptidase inhibitor, clade B (ovalbumin), member 5	0.013
POM121	POM121 membrane glycoprotein	0.013
TCHP	trichoplein, keratin filament binding	0.013
SHOC2	soc-2 suppressor of clear homolog (C. elegans)	0.013
MAPRE1	microtubule-associated protein, RP/EB family, member 1	0.013
FGFBP1	fibroblast growth factor binding protein 1	0.013
MT4	metallothionein 4	0.013
PEBP4	phosphatidylethanolamine-binding protein 4	0.013
RHPN1	rhophilin, Rho GTPase binding protein 1	0.013
TMCO6	transmembrane and coiled-coil domains 6	0.012
SPTAN1	spectrin, alpha, non-erythrocytic 1 (alpha-fodrin)	0.012
KRT83	keratin 83	0.012	Human
EVC2	Ellis van Creveld syndrome 2	0.012
DSC1	desmocollin 1	0.012
CDH3	cadherin 3, type 1, P-cadherin (placental)	0.012
PADI3	peptidyl arginine deiminase, type III	0.012
S100A2	S100 calcium binding protein A2	0.012
RIC8A	resistance to inhibitors of cholinesterase 8 homolog A (C. elegans)	0.012
C7orf36	chromosome 7 open reading frame 36	0.012
ABI1	abl-interactor 1	0.012
S100A7	S100 calcium binding protein A7	0.011
GOPC	golgi-associated PDZ and coiled-coil motif containing	0.011
SPINT1	serine peptidase inhibitor, Kunitz type 1	0.011
CYP11A1	cytochrome P450, family 11, subfamily A, polypeptide 1	0.011
GABRP	gamma-aminobutyric acid (GABA) A receptor, pi	0.011
CDH15	cadherin 15, type 1, M-cadherin (myotubule)	0.011
CRCT1	cysteine-rich C-terminal 1	0.011
RASSF7	Ras association (RalGDS/AF-6) domain family (N-terminal) member 7	0.011
TNS4	tensin 4	0.011
CST6	cystatin E/M	0.011
EDN2	endothelin 2	0.010
TRIP6	thyroid hormone receptor interactor 6	0.010
SERPINB13	serpin peptidase inhibitor, clade B (ovalbumin), member 13	0.010
NEFM	neurofilament, medium polypeptide	0.010	Human Mouse
SACM1L	SAC1 suppressor of actin mutations 1-like (yeast)	0.010
FAM190B	family with sequence similarity 190, member B	0.010