IMP
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positive regulation of endothelial cell chemotaxis by vegf activated vascular endothelial growth factor receptor signaling pathway
A series of molecular signals initiated by the binding of a vascular endothelial growth factor (VEGF) to a VEGFR on the surface of a cell, which activates or increases the frequency, rate or extent of endothelial cell chemotaxis.
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Click on a gene's description to view its network relationships with genes known to be involved in "positive regulation of endothelial cell chemotaxis by vegf activated vascular endothelial growth factor receptor signaling pathway"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| PDGFRA | platelet-derived growth factor receptor, alpha polypeptide | 1.000 | ||
| FLT1 | fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) | 1.000 | ||
| NRP1 | neuropilin 1 | 1.000 | ||
| VEGFA | vascular endothelial growth factor A | 0.999 | ||
| HSPB8 | heat shock 22kDa protein 8 | 0.984 | Human | |
| PDGFRB | platelet-derived growth factor receptor, beta polypeptide | 0.983 | ||
| BAG3 | BCL2-associated athanogene 3 | 0.942 | ||
| PDGFB | platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog) | 0.917 | Human | |
| PGF | placental growth factor | 0.907 | Human | |
| KDR | kinase insert domain receptor (a type III receptor tyrosine kinase) | 0.901 | ||
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | 0.497 | ||
| PDGFA | platelet-derived growth factor alpha polypeptide | 0.480 | Human | |
| HDAC7 | histone deacetylase 7 | 0.406 | ||
| PLCG1 | phospholipase C, gamma 1 | 0.364 | ||
| RRBP1 | ribosome binding protein 1 homolog 180kDa (dog) | 0.272 | ||
| PDGFC | platelet derived growth factor C | 0.240 | ||
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.215 | ||
| COL5A1 | collagen, type V, alpha 1 | 0.205 | ||
| COL4A1 | collagen, type IV, alpha 1 | 0.172 | ||
| CRKL | v-crk sarcoma virus CT10 oncogene homolog (avian)-like | 0.160 | ||
| COL6A1 | collagen, type VI, alpha 1 | 0.158 | ||
| HSPB7 | heat shock 27kDa protein family, member 7 (cardiovascular) | 0.146 | ||
| PTPRB | protein tyrosine phosphatase, receptor type, B | 0.141 | ||
| SNRNP70 | small nuclear ribonucleoprotein 70kDa (U1) | 0.103 | ||
| DDIT4 | DNA-damage-inducible transcript 4 | 0.085 | ||
| CRK | v-crk sarcoma virus CT10 oncogene homolog (avian) | 0.073 | ||
| PDLIM7 | PDZ and LIM domain 7 (enigma) | 0.071 | ||
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide | 0.068 | ||
| COL1A1 | collagen, type I, alpha 1 | 0.055 | ||
| GORASP1 | golgi reassembly stacking protein 1, 65kDa | 0.046 | ||
| HSF1 | heat shock transcription factor 1 | 0.039 | ||
| CAV1 | caveolin 1, caveolae protein, 22kDa | 0.038 | ||
| HSPA1B | heat shock 70kDa protein 1B | 0.033 | ||
| MT2A | metallothionein 2A | 0.030 | ||
| LDLR | low density lipoprotein receptor | 0.026 | ||
| COL4A2 | collagen, type IV, alpha 2 | 0.023 | ||
| COL1A2 | collagen, type I, alpha 2 | 0.020 | ||
| CRYAB | crystallin, alpha B | 0.019 | ||
| STC1 | stanniocalcin 1 | 0.016 | ||
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.016 | ||
| COL2A1 | collagen, type II, alpha 1 | 0.015 | ||
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.015 | ||
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.014 | ||
| THBS1 | thrombospondin 1 | 0.013 | ||
| MAPKAPK2 | mitogen-activated protein kinase-activated protein kinase 2 | 0.013 | ||
| NUDT3 | nudix (nucleoside diphosphate linked moiety X)-type motif 3 | 0.013 | ||
| HSPA1A | heat shock 70kDa protein 1A | 0.012 | ||
| OSMR | oncostatin M receptor | 0.011 | ||
| HSPG2 | heparan sulfate proteoglycan 2 | 0.011 | ||
| MED25 | mediator complex subunit 25 | 0.011 | ||
| FZD4 | frizzled homolog 4 (Drosophila) | 0.010 |