IMP
Process View
negative regulation of actin filament polymerization
Any process that stops, prevents, or reduces the frequency, rate or extent of actin polymerization.
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In addition to gene-name show these genes:
Click on a gene's description to view its network relationships with genes known to be involved in "negative regulation of actin filament polymerization"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| Arpc4 | actin related protein 2/3 complex, subunit 4 | 0.640 | ||
| Rac1 | RAS-related C3 botulinum substrate 1 | 0.529 | ||
| Ywhaz | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide | 0.408 | ||
| Sept7 | septin 7 | 0.358 | ||
| Arhgdia | Rho GDP dissociation inhibitor (GDI) alpha | 0.299 | ||
| Actr3 | ARP3 actin-related protein 3 homolog (yeast) | 0.296 | ||
| Akt1 | thymoma viral proto-oncogene 1 | 0.293 | Mouse | |
| Vasp | vasodilator-stimulated phosphoprotein | 0.176 | ||
| Cdc42 | cell division cycle 42 homolog (S. cerevisiae) | 0.172 | ||
| Wdr1 | WD repeat domain 1 | 0.141 | Yeast Worm | |
| Actb | actin, beta | 0.101 | ||
| Gnb2 | guanine nucleotide binding protein (G protein), beta 2 | 0.099 | ||
| Pfn1 | profilin 1 | 0.087 | Human Mouse | |
| Robo1 | roundabout homolog 1 (Drosophila) | 0.082 | ||
| Rhoa | ras homolog gene family, member A | 0.075 | ||
| Adam10 | a disintegrin and metallopeptidase domain 10 | 0.069 | ||
| Arhgap1 | Rho GTPase activating protein 1 | 0.068 | ||
| Msn | moesin | 0.061 | ||
| Rap1b | RAS related protein 1b | 0.060 | ||
| Arf1 | ADP-ribosylation factor 1 | 0.059 | ||
| Abi1 | abl-interactor 1 | 0.056 | ||
| Robo2 | roundabout homolog 2 (Drosophila) | 0.054 | ||
| Ptp4a2 | protein tyrosine phosphatase 4a2 | 0.046 | ||
| Necap2 | NECAP endocytosis associated 2 | 0.042 | ||
| Mobkl1b | MOB1, Mps One Binder kinase activator-like 1B (yeast) | 0.041 | ||
| Gnb1 | guanine nucleotide binding protein (G protein), beta 1 | 0.041 | ||
| Cltc | clathrin, heavy polypeptide (Hc) | 0.040 | ||
| Cd28 | CD28 antigen | 0.039 | ||
| Capn1 | calpain 1 | 0.039 | ||
| Slit3 | slit homolog 3 (Drosophila) | 0.038 | ||
| Dbnl | drebrin-like | 0.038 | ||
| Hif1a | hypoxia inducible factor 1, alpha subunit | 0.035 | ||
| Rod1 | ROD1 regulator of differentiation 1 (S. pombe) | 0.033 | ||
| Ldb3 | LIM domain binding 3 | 0.031 | ||
| Pard3 | par-3 (partitioning defective 3) homolog (C. elegans) | 0.030 | ||
| Arrb2 | arrestin, beta 2 | 0.029 | ||
| Cfl1 | cofilin 1, non-muscle | 0.026 | ||
| Sept9 | septin 9 | 0.026 | ||
| Ywhah | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide | 0.025 | ||
| Gmfb | glia maturation factor, beta | 0.025 | ||
| Vhl | von Hippel-Lindau tumor suppressor | 0.024 | ||
| Prkce | protein kinase C, epsilon | 0.024 | ||
| Actn2 | actinin alpha 2 | 0.024 | ||
| Mapkap1 | mitogen-activated protein kinase associated protein 1 | 0.024 | ||
| Nckap1 | NCK-associated protein 1 | 0.024 | ||
| Dnm1 | dynamin 1 | 0.023 | ||
| Capzb | capping protein (actin filament) muscle Z-line, beta | 0.023 | ||
| Klf6 | Kruppel-like factor 6 | 0.022 | ||
| Slc25a24 | solute carrier family 25 (mitochondrial carrier, phosphate carrier), member 24 | 0.022 | ||
| Stx7 | syntaxin 7 | 0.022 | ||
| Gnai2 | guanine nucleotide binding protein (G protein), alpha inhibiting 2 | 0.022 | ||
| Csrp1 | cysteine and glycine-rich protein 1 | 0.021 | ||
| Mlf2 | myeloid leukemia factor 2 | 0.020 | ||
| Ilk | integrin linked kinase | 0.020 | ||
| Actr2 | ARP2 actin-related protein 2 homolog (yeast) | 0.020 | ||
| Btbd10 | BTB (POZ) domain containing 10 | 0.020 | ||
| Ppp1ca | protein phosphatase 1, catalytic subunit, alpha isoform | 0.020 | ||
| Prkar1a | protein kinase, cAMP dependent regulatory, type I, alpha | 0.019 | ||
| Epb4.1l2 | erythrocyte protein band 4.1-like 2 | 0.019 | ||
| Cap1 | CAP, adenylate cyclase-associated protein 1 (yeast) | 0.018 | ||
| Ppp3ca | protein phosphatase 3, catalytic subunit, alpha isoform | 0.018 | ||
| Cd151 | CD151 antigen | 0.017 | ||
| Plekho1 | pleckstrin homology domain containing, family O member 1 | 0.017 | ||
| Rhog | ras homolog gene family, member G | 0.017 | ||
| Akt2 | thymoma viral proto-oncogene 2 | 0.016 | Mouse | |
| Prkca | protein kinase C, alpha | 0.016 | ||
| Ppp4c | protein phosphatase 4, catalytic subunit | 0.016 | ||
| Rhob | ras homolog gene family, member B | 0.016 | ||
| Tmod3 | tropomodulin 3 | 0.016 | ||
| Lims1 | LIM and senescent cell antigen-like domains 1 | 0.016 | ||
| Adam9 | a disintegrin and metallopeptidase domain 9 (meltrin gamma) | 0.015 | ||
| Calm1 | calmodulin 1 | 0.015 | ||
| Siah2 | seven in absentia 2 | 0.015 | ||
| Sdcbp | syndecan binding protein | 0.015 | ||
| Cyfip1 | cytoplasmic FMR1 interacting protein 1 | 0.015 | ||
| Sh3kbp1 | SH3-domain kinase binding protein 1 | 0.015 | ||
| Prkcb | protein kinase C, beta | 0.015 | ||
| Rbms1 | RNA binding motif, single stranded interacting protein 1 | 0.015 | ||
| Grb2 | growth factor receptor bound protein 2 | 0.015 | ||
| Bcl10 | B-cell leukemia/lymphoma 10 | 0.014 | ||
| Csde1 | cold shock domain containing E1, RNA binding | 0.014 | ||
| Rap1gds1 | RAP1, GTP-GDP dissociation stimulator 1 | 0.014 | ||
| Pitpna | phosphatidylinositol transfer protein, alpha | 0.014 | ||
| Slc39a7 | solute carrier family 39 (zinc transporter), member 7 | 0.014 | ||
| Psap | prosaposin | 0.014 | ||
| Ehmt2 | euchromatic histone lysine N-methyltransferase 2 | 0.014 | ||
| Csnk1g2 | casein kinase 1, gamma 2 | 0.013 | ||
| Wsb2 | WD repeat and SOCS box-containing 2 | 0.013 | ||
| Crim1 | cysteine rich transmembrane BMP regulator 1 (chordin like) | 0.013 | ||
| Ugcg | UDP-glucose ceramide glucosyltransferase | 0.013 | ||
| Ppp2r5c | protein phosphatase 2, regulatory subunit B (B56), gamma isoform | 0.013 | ||
| Apaf1 | apoptotic peptidase activating factor 1 | 0.013 | ||
| Capza2 | capping protein (actin filament) muscle Z-line, alpha 2 | 0.013 | Mouse | |
| Fam49b | family with sequence similarity 49, member B | 0.013 | ||
| Wasf1 | WASP family 1 | 0.013 | ||
| Csk | c-src tyrosine kinase | 0.012 | ||
| Ctnnd1 | catenin (cadherin associated protein), delta 1 | 0.012 | ||
| Rtn4 | reticulon 4 | 0.012 | ||
| Gna12 | guanine nucleotide binding protein, alpha 12 | 0.012 | ||
| Jak1 | Janus kinase 1 | 0.012 | ||
| Cab39 | calcium binding protein 39 | 0.012 | ||
| Rab11a | RAB11a, member RAS oncogene family | 0.012 | ||
| Kctd20 | potassium channel tetramerisation domain containing 20 | 0.012 | ||
| Cnn2 | calponin 2 | 0.011 | ||
| Arpc2 | actin related protein 2/3 complex, subunit 2 | 0.011 | ||
| Ap2a2 | adaptor protein complex AP-2, alpha 2 subunit | 0.011 | ||
| Arrb1 | arrestin, beta 1 | 0.011 | ||
| Dync1i2 | dynein cytoplasmic 1 intermediate chain 2 | 0.011 | ||
| Enah | enabled homolog (Drosophila) | 0.011 | ||
| Atp6v1c1 | ATPase, H+ transporting, lysosomal V1 subunit C1 | 0.011 | ||
| Rap2c | RAP2C, member of RAS oncogene family | 0.011 | ||
| Cdc42se1 | CDC42 small effector 1 | 0.011 | ||
| Wipf1 | WAS/WASL interacting protein family, member 1 | 0.011 | ||
| Cdk14 | cyclin-dependent kinase 14 | 0.011 | ||
| Pacs2 | phosphofurin acidic cluster sorting protein 2 | 0.011 | ||
| Abr | active BCR-related gene | 0.011 | ||
| Sec14l1 | SEC14-like 1 (S. cerevisiae) | 0.011 | ||
| 3110003A17Rik | RIKEN cDNA 3110003A17 gene | 0.011 | ||
| Coro1a | coronin, actin binding protein 1A | 0.010 | ||
| Ptpn22 | protein tyrosine phosphatase, non-receptor type 22 (lymphoid) | 0.010 | ||
| Fzr1 | fizzy/cell division cycle 20 related 1 (Drosophila) | 0.010 | ||
| Acbd3 | acyl-Coenzyme A binding domain containing 3 | 0.010 | ||
| Tnfrsf13b | tumor necrosis factor receptor superfamily, member 13b | 0.010 | ||
| Rab7 | RAB7, member RAS oncogene family | 0.010 | ||
| Bcl2 | B-cell leukemia/lymphoma 2 | 0.010 | ||
| Cttn | cortactin | 0.010 | ||
| Snx6 | sorting nexin 6 | 0.010 | ||
| Stk10 | serine/threonine kinase 10 | 0.010 |