IMP

Process View

Mus musculus

2 genes annotated in mouse

positive regulation of plasminogen activation

Any process that increases the rate, frequency or extent of plasminogen activation. Plasminogen activation is the process in which plasminogen is processed to plasmin.

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "positive regulation of plasminogen activation"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "positive regulation of plasminogen activation" (in gray)

Name	Description	Probability	Func Analog Organism
Itih1	inter-alpha trypsin inhibitor, heavy chain 1	0.650
Cldn3	claudin 3	0.532
Asgr2	asialoglycoprotein receptor 2	0.487
Ambp	alpha 1 microglobulin/bikunin	0.440
F2	coagulation factor II	0.363
Apoa1	apolipoprotein A-I	0.292
Serpina10	serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10	0.251
Cyp2d10	cytochrome P450, family 2, subfamily d, polypeptide 10	0.225
Plg	plasminogen	0.170
Akr1c6	aldo-keto reductase family 1, member C6	0.170
Pzp	pregnancy zone protein	0.168
Hc	hemolytic complement	0.155
Ager	advanced glycosylation end product-specific receptor	0.149
Prodh2	proline dehydrogenase (oxidase) 2	0.145
Clic3	chloride intracellular channel 3	0.141
Ces1c	carboxylesterase 1C	0.130
Itih4	inter alpha-trypsin inhibitor, heavy chain 4	0.121
Lipc	lipase, hepatic	0.120
Cpn1	carboxypeptidase N, polypeptide 1	0.112
Agxt	alanine-glyoxylate aminotransferase	0.108
Kng1	kininogen 1	0.100
Slc27a5	solute carrier family 27 (fatty acid transporter), member 5	0.099
Mst1	macrophage stimulating 1 (hepatocyte growth factor-like)	0.096
Bik	BCL2-interacting killer	0.091
Foxa2	forkhead box A2	0.086
Cfi	complement component factor i	0.085
Fgfr4	fibroblast growth factor receptor 4	0.082
F13b	coagulation factor XIII, beta subunit	0.072
Fxyd1	FXYD domain-containing ion transport regulator 1	0.071
Serpinc1	serine (or cysteine) peptidase inhibitor, clade C (antithrombin), member 1	0.070
H1foo	H1 histone family, member O, oocyte-specific	0.070
Col13a1	collagen, type XIII, alpha 1	0.066
Tff2	trefoil factor 2 (spasmolytic protein 1)	0.065
Mat1a	methionine adenosyltransferase I, alpha	0.065
Apoc4	apolipoprotein C-IV	0.061
Asgr1	asialoglycoprotein receptor 1	0.060
Igfbp6	insulin-like growth factor binding protein 6	0.059
Ahsg	alpha-2-HS-glycoprotein	0.059
Pcdh12	protocadherin 12	0.057
Cyp8b1	cytochrome P450, family 8, subfamily b, polypeptide 1	0.053
Gm6484	predicted gene 6484	0.053
Tnxb	tenascin XB	0.052
Nr1i3	nuclear receptor subfamily 1, group I, member 3	0.052
Ttc36	tetratricopeptide repeat domain 36	0.052
Cpn2	carboxypeptidase N, polypeptide 2	0.052
Proc	protein C	0.051
Gc	group specific component	0.051
Cyp2c70	cytochrome P450, family 2, subfamily c, polypeptide 70	0.050
Snx2	sorting nexin 2	0.050
Slc22a1	solute carrier family 22 (organic cation transporter), member 1	0.049
F12	coagulation factor XII (Hageman factor)	0.045	Human
Apof	apolipoprotein F	0.043
Krt79	keratin 79	0.043
Apoh	apolipoprotein H	0.042
Csrp3	cysteine and glycine-rich protein 3	0.042
Itih2	inter-alpha trypsin inhibitor, heavy chain 2	0.041
Inhbe	inhibin beta E	0.041
Plunc	palate, lung, and nasal epithelium associated	0.041
Apoa5	apolipoprotein A-V	0.041
Afm	afamin	0.039
Ern2	endoplasmic reticulum (ER) to nucleus signalling 2	0.036
Hgd	homogentisate 1, 2-dioxygenase	0.036
Hpx	hemopexin	0.036
Tekt2	tektin 2	0.035
U46068	cDNA sequence U46068	0.035
Serpinf2	serine (or cysteine) peptidase inhibitor, clade F, member 2	0.034
1300017J02Rik	RIKEN cDNA 1300017J02 gene	0.034
Mfap5	microfibrillar associated protein 5	0.033
C4bp	complement component 4 binding protein	0.033
Nmi	N-myc (and STAT) interactor	0.033
Gjb1	gap junction protein, beta 1	0.032
Fgg	fibrinogen gamma chain	0.032
Mt4	metallothionein 4	0.032
Abcc6	ATP-binding cassette, sub-family C (CFTR/MRP), member 6	0.032
Hamp	hepcidin antimicrobial peptide	0.032
Wnt5b	wingless-related MMTV integration site 5B	0.031
Cldn7	claudin 7	0.031
Sdsl	serine dehydratase-like	0.031
C9	complement component 9	0.030
Cnn1	calponin 1	0.030
Apom	apolipoprotein M	0.030
Wfdc2	WAP four-disulfide core domain 2	0.030
Fabp1	fatty acid binding protein 1, liver	0.029
Rdh7	retinol dehydrogenase 7	0.029
Sycn	syncollin	0.029
Fgb	fibrinogen beta chain	0.028
Serpina12	serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 12	0.027
Proz	protein Z, vitamin K-dependent plasma glycoprotein	0.027
Ivl	involucrin	0.026
Mug2	murinoglobulin 2	0.026
Foxa1	forkhead box A1	0.026
Ccbp2	chemokine binding protein 2	0.026
Fut2	fucosyltransferase 2	0.026
AU021092	expressed sequence AU021092	0.026
Sftpb	surfactant associated protein B	0.026
Amdhd1	amidohydrolase domain containing 1	0.025
Habp2	hyaluronic acid binding protein 2	0.025
Gja4	gap junction protein, alpha 4	0.025
Aadat	aminoadipate aminotransferase	0.025
Apoa4	apolipoprotein A-IV	0.025
Col17a1	collagen, type XVII, alpha 1	0.024
Cyp7a1	cytochrome P450, family 7, subfamily a, polypeptide 1	0.024
Slc39a4	solute carrier family 39 (zinc transporter), member 4	0.023
Acsm1	acyl-CoA synthetase medium-chain family member 1	0.023
Dio1	deiodinase, iodothyronine, type I	0.022
Gdf15	growth differentiation factor 15	0.022
Serpind1	serine (or cysteine) peptidase inhibitor, clade D, member 1	0.022
Klkb1	kallikrein B, plasma 1	0.021
Myl7	myosin, light polypeptide 7, regulatory	0.021
Vnn3	vanin 3	0.021
Hal	histidine ammonia lyase	0.021
Matn4	matrilin 4	0.021
Adra1b	adrenergic receptor, alpha 1b	0.021
Ccdc90b	coiled-coil domain containing 90B	0.020
Hgfac	hepatocyte growth factor activator	0.020
Fam167b	family with sequence similarity 167, member B	0.020
Ces1e	carboxylesterase 1E	0.020
Cyp2f2	cytochrome P450, family 2, subfamily f, polypeptide 2	0.020
Serpina3k	serine (or cysteine) peptidase inhibitor, clade A, member 3K	0.020
Hrg	histidine-rich glycoprotein	0.020
Clec4f	C-type lectin domain family 4, member f	0.019
BC051019	cDNA sequence BC051019	0.019
Rhox6	reproductive homeobox 6	0.019
Aldob	aldolase B, fructose-bisphosphate	0.019
Inhbc	inhibin beta-C	0.019
Otc	ornithine transcarbamylase	0.019
Agmat	agmatine ureohydrolase (agmatinase)	0.019
Ly6g6d	lymphocyte antigen 6 complex, locus G6D	0.018
Pah	phenylalanine hydroxylase	0.018
Pigr	polymeric immunoglobulin receptor	0.018
Prph2	peripherin 2	0.018
Slc25a47	solute carrier family 25, member 47	0.018
Pdzk1ip1	PDZK1 interacting protein 1	0.017
Klk1b4	kallikrein 1-related pepidase b4	0.017
Rgn	regucalcin	0.017
Cldn18	claudin 18	0.017
Mup3	major urinary protein 3	0.017
Rab17	RAB17, member RAS oncogene family	0.017
Rab25	RAB25, member RAS oncogene family	0.017
Spp2	secreted phosphoprotein 2	0.017
Krt25	keratin 25	0.017
Krt8	keratin 8	0.016
Abcc2	ATP-binding cassette, sub-family C (CFTR/MRP), member 2	0.016
Sec14l2	SEC14-like 2 (S. cerevisiae)	0.016
Igfals	insulin-like growth factor binding protein, acid labile subunit	0.016
Fabp2	fatty acid binding protein 2, intestinal	0.016
Nr0b2	nuclear receptor subfamily 0, group B, member 2	0.015
Gnmt	glycine N-methyltransferase	0.015
F9	coagulation factor IX	0.015
Scgb3a2	secretoglobin, family 3A, member 2	0.015
Cyp2j5	cytochrome P450, family 2, subfamily j, polypeptide 5	0.015
Aqp8	aquaporin 8	0.015
Gyg	glycogenin	0.015
Agrp	agouti related protein	0.014
Tekt1	tektin 1	0.014
Itih3	inter-alpha trypsin inhibitor, heavy chain 3	0.014
Spg21	spastic paraplegia 21 homolog (human)	0.014
Gfi1b	growth factor independent 1B	0.014
Fndc7	fibronectin type III domain containing 7	0.014
Cela1	chymotrypsin-like elastase family, member 1	0.014
C8g	complement component 8, gamma polypeptide	0.014
Ropn1l	ropporin 1-like	0.014
Tcea3	transcription elongation factor A (SII), 3	0.014
Cidec	cell death-inducing DFFA-like effector c	0.014
Cfd	complement factor D (adipsin)	0.014
Sardh	sarcosine dehydrogenase	0.014
Mug1	murinoglobulin 1	0.014
Mbl1	mannose-binding lectin (protein A) 1	0.014	Mouse
Ces3a	carboxylesterase 3A	0.014
Orm1	orosomucoid 1	0.014
Keg1	kidney expressed gene 1	0.014
Abcb11	ATP-binding cassette, sub-family B (MDR/TAP), member 11	0.013
F11	coagulation factor XI	0.013
Clec3b	C-type lectin domain family 3, member b	0.013
Col6a2	collagen, type VI, alpha 2	0.013
Orm2	orosomucoid 2	0.013
Eln	elastin	0.013
Akr1c20	aldo-keto reductase family 1, member C20	0.013
Fgf17	fibroblast growth factor 17	0.013
Pno1	partner of NOB1 homolog (S. cerevisiae)	0.013
Mdfi	MyoD family inhibitor	0.013
Morn3	MORN repeat containing 3	0.013
Slc2a2	solute carrier family 2 (facilitated glucose transporter), member 2	0.013
Cela2a	chymotrypsin-like elastase family, member 2A	0.013
Sod3	superoxide dismutase 3, extracellular	0.013
Cst8	cystatin 8 (cystatin-related epididymal spermatogenic)	0.013
Tmem30b	transmembrane protein 30B	0.012
Iyd	iodotyrosine deiodinase	0.012
Cxcl15	chemokine (C-X-C motif) ligand 15	0.012
Lyrm2	LYR motif containing 2	0.012
Tulp2	tubby-like protein 2	0.012
Fhit	fragile histidine triad gene	0.012
Msln	mesothelin	0.012
Pth1r	parathyroid hormone 1 receptor	0.012
Cyp2b10	cytochrome P450, family 2, subfamily b, polypeptide 10	0.012
Apob	apolipoprotein B	0.012
Rdh16	retinol dehydrogenase 16	0.012
Apoc1	apolipoprotein C-I	0.012
Slc23a1	solute carrier family 23 (nucleobase transporters), member 1	0.012
Pbld1	phenazine biosynthesis-like protein domain containing 1	0.012
C8b	complement component 8, beta polypeptide	0.011
Alox12e	arachidonate lipoxygenase, epidermal	0.011
Tnni3	troponin I, cardiac 3	0.011
Pnliprp2	pancreatic lipase-related protein 2	0.011
Cldn2	claudin 2	0.011
Pla2g4f	phospholipase A2, group IVF	0.011
Aox3	aldehyde oxidase 3	0.011
Muc1	mucin 1, transmembrane	0.011
Cyp1a2	cytochrome P450, family 1, subfamily a, polypeptide 2	0.011
G6pc	glucose-6-phosphatase, catalytic	0.011
Car5a	carbonic anhydrase 5a, mitochondrial	0.011
Gpx7	glutathione peroxidase 7	0.011
Gnpda2	glucosamine-6-phosphate deaminase 2	0.011
Pdcd1	programmed cell death 1	0.011
Azgp1	alpha-2-glycoprotein 1, zinc	0.011
F7	coagulation factor VII	0.011
Mbl2	mannose-binding lectin (protein C) 2	0.011	Mouse
Ces1g	carboxylesterase 1G	0.011
Sftpc	surfactant associated protein C	0.011
Prx	periaxin	0.011
Hpn	hepsin	0.010	Human
Fga	fibrinogen alpha chain	0.010
Copz2	coatomer protein complex, subunit zeta 2	0.010
F10	coagulation factor X	0.010
Areg	amphiregulin	0.010
Apoa2	apolipoprotein A-II	0.010
Zfand1	zinc finger, AN1-type domain 1	0.010
AI428936	expressed sequence AI428936	0.010
S100g	S100 calcium binding protein G	0.010
Dram2	VDNA-damage regulated autophagy modulator 2	0.010
Fgl1	fibrinogen-like protein 1	0.010
Mfap4	microfibrillar-associated protein 4	0.010
Mrap	melanocortin 2 receptor accessory protein	0.010
Wnt11	wingless-related MMTV integration site 11	0.010
Tg	thyroglobulin	0.010
Slc44a4	solute carrier family 44, member 4	0.010
Cd248	CD248 antigen, endosialin	0.010
Sox18	SRY-box containing gene 18	0.010