IMP
Process View
proximal tubule development
The process whose specific outcome is the progression of the proximal tubule over time, from its formation to the mature structure. In mammals, the proximal tubule is a nephron tubule that connects Bowman's capsule to the descending thin limb of the loop of Henle. It has a brush border epithelial morphology.
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In addition to gene-name show these genes:
Click on a gene's description to view its network relationships with genes known to be involved in "proximal tubule development"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| Notch1 | Notch gene homolog 1 (Drosophila) | 1.000 | Mouse | |
| Jag1 | jagged 1 | 0.949 | Mouse | |
| Dll1 | delta-like 1 (Drosophila) | 0.847 | ||
| Efnb2 | ephrin B2 | 0.688 | ||
| Rbpj | recombination signal binding protein for immunoglobulin kappa J region | 0.542 | ||
| Psen1 | presenilin 1 | 0.520 | ||
| Notch2 | Notch gene homolog 2 (Drosophila) | 0.318 | ||
| Gata4 | GATA binding protein 4 | 0.302 | ||
| Pax2 | paired box gene 2 | 0.085 | ||
| Pkd1 | polycystic kidney disease 1 homolog | 0.070 | Human | |
| Foxc1 | forkhead box C1 | 0.070 | ||
| Psen2 | presenilin 2 | 0.065 | ||
| Meox2 | mesenchyme homeobox 2 | 0.065 | ||
| Fgfr1 | fibroblast growth factor receptor 1 | 0.058 | ||
| Rxra | retinoid X receptor alpha | 0.058 | ||
| Pax3 | paired box gene 3 | 0.054 | ||
| Pitx2 | paired-like homeodomain transcription factor 2 | 0.053 | ||
| Cys1 | cystin 1 | 0.045 | ||
| Hoxa1 | homeobox A1 | 0.042 | ||
| Vangl2 | vang-like 2 (van gogh, Drosophila) | 0.034 | ||
| Nkx2-5 | NK2 transcription factor related, locus 5 (Drosophila) | 0.029 | ||
| Nos3 | nitric oxide synthase 3, endothelial cell | 0.028 | ||
| Tgfb2 | transforming growth factor, beta 2 | 0.025 | ||
| Adam19 | a disintegrin and metallopeptidase domain 19 (meltrin beta) | 0.020 | ||
| Egfl7 | EGF-like domain 7 | 0.020 | ||
| Chd7 | chromodomain helicase DNA binding protein 7 | 0.020 | ||
| Foxc2 | forkhead box C2 | 0.019 | ||
| Efnb1 | ephrin B1 | 0.019 | ||
| Lama5 | laminin, alpha 5 | 0.018 | ||
| Wt1 | Wilms tumor 1 homolog | 0.018 | ||
| Smad6 | MAD homolog 6 (Drosophila) | 0.016 | ||
| Hes1 | hairy and enhancer of split 1 (Drosophila) | 0.015 | ||
| Bicc1 | bicaudal C homolog 1 (Drosophila) | 0.014 | ||
| Notch3 | Notch gene homolog 3 (Drosophila) | 0.014 | Mouse | |
| Megf8 | multiple EGF-like-domains 8 | 0.014 | ||
| Mycn | v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian) | 0.013 | ||
| Zfpm2 | zinc finger protein, multitype 2 | 0.013 | ||
| Nrarp | Notch-regulated ankyrin repeat protein | 0.013 | ||
| Ntf3 | neurotrophin 3 | 0.012 | ||
| Jag2 | jagged 2 | 0.012 | Mouse | |
| Dll4 | delta-like 4 (Drosophila) | 0.012 | Mouse | |
| Hspg2 | perlecan (heparan sulfate proteoglycan 2) | 0.011 | ||
| Cited2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 0.011 | ||
| Cdkn1a | cyclin-dependent kinase inhibitor 1A (P21) | 0.010 |