IMP
Process View
acrosome reaction
The discharge, by sperm, of a single, anterior secretory granule following the sperm's attachment to the zona pellucida surrounding the oocyte. The process begins with the fusion of the outer acrosomal membrane with the sperm plasma membrane and ends with the exocytosis of the acrosomal contents into the egg.
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In addition to gene-name show these genes:
Click on a gene's description to view its network relationships with genes known to be involved in "acrosome reaction"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| Gabrb2 | gamma-aminobutyric acid (GABA) A receptor, subunit beta 2 | 0.434 | Mouse | |
| Snap25 | synaptosomal-associated protein 25 | 0.129 | ||
| Syt2 | synaptotagmin II | 0.122 | Mouse | |
| Grid1 | glutamate receptor, ionotropic, delta 1 | 0.103 | ||
| Gabrb3 | gamma-aminobutyric acid (GABA) A receptor, subunit beta 3 | 0.065 | Mouse | |
| Gabrg2 | gamma-aminobutyric acid (GABA) A receptor, subunit gamma 2 | 0.064 | Mouse | |
| Syt6 | synaptotagmin VI | 0.060 | ||
| Syn2 | synapsin II | 0.057 | ||
| Syp | synaptophysin | 0.055 | ||
| Prkcc | protein kinase C, gamma | 0.051 | ||
| Slc12a5 | solute carrier family 12, member 5 | 0.050 | ||
| Cdh8 | cadherin 8 | 0.050 | ||
| Gria4 | glutamate receptor, ionotropic, AMPA4 (alpha 4) | 0.048 | ||
| Nxph1 | neurexophilin 1 | 0.044 | ||
| Sycp1 | synaptonemal complex protein 1 | 0.042 | ||
| Gad2 | glutamic acid decarboxylase 2 | 0.042 | ||
| Vamp2 | vesicle-associated membrane protein 2 | 0.042 | ||
| Kcnab3 | potassium voltage-gated channel, shaker-related subfamily, beta member 3 | 0.040 | ||
| Bsn | bassoon | 0.039 | ||
| Cys1 | cystin 1 | 0.039 | ||
| Kif1a | kinesin family member 1A | 0.035 | ||
| Adcyap1 | adenylate cyclase activating polypeptide 1 | 0.034 | ||
| Sh3gl2 | SH3-domain GRB2-like 2 | 0.033 | ||
| Kcna6 | potassium voltage-gated channel, shaker-related, subfamily, member 6 | 0.032 | ||
| Grm8 | glutamate receptor, metabotropic 8 | 0.032 | ||
| Gabra1 | gamma-aminobutyric acid (GABA) A receptor, subunit alpha 1 | 0.032 | Mouse | |
| Scn8a | sodium channel, voltage-gated, type VIII, alpha | 0.031 | ||
| Neto1 | neuropilin (NRP) and tolloid (TLL)-like 1 | 0.030 | ||
| B3galt1 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 | 0.029 | ||
| Cdh9 | cadherin 9 | 0.028 | ||
| Syt7 | synaptotagmin VII | 0.028 | Mouse | |
| Stx1b | syntaxin 1B | 0.028 | Mouse | |
| Shc3 | src homology 2 domain-containing transforming protein C3 | 0.027 | ||
| Megf8 | multiple EGF-like-domains 8 | 0.026 | ||
| Pcsk1 | proprotein convertase subtilisin/kexin type 1 | 0.026 | Mouse | |
| Gabrg1 | gamma-aminobutyric acid (GABA) A receptor, subunit gamma 1 | 0.026 | ||
| Nrg3 | neuregulin 3 | 0.025 | ||
| Hcn1 | hyperpolarization-activated, cyclic nucleotide-gated K+ 1 | 0.024 | ||
| Meox2 | mesenchyme homeobox 2 | 0.024 | ||
| Kcnh1 | potassium voltage-gated channel, subfamily H (eag-related), member 1 | 0.024 | ||
| Crhr1 | corticotropin releasing hormone receptor 1 | 0.023 | ||
| Rnf112 | ring finger protein 112 | 0.023 | ||
| Slc1a6 | solute carrier family 1 (high affinity aspartate/glutamate transporter), member 6 | 0.023 | ||
| Grik2 | glutamate receptor, ionotropic, kainate 2 (beta 2) | 0.023 | ||
| Rit2 | Ras-like without CAAX 2 | 0.023 | ||
| Napb | N-ethylmaleimide sensitive fusion protein attachment protein beta | 0.022 | ||
| Syt10 | synaptotagmin X | 0.022 | Mouse | |
| Kcnd3 | potassium voltage-gated channel, Shal-related family, member 3 | 0.022 | ||
| Ids | iduronate 2-sulfatase | 0.021 | ||
| Dab1 | disabled homolog 1 (Drosophila) | 0.021 | ||
| Oprl1 | opioid receptor-like 1 | 0.021 | ||
| Kifc2 | kinesin family member C2 | 0.021 | ||
| Grm1 | glutamate receptor, metabotropic 1 | 0.021 | ||
| Cdh10 | cadherin 10 | 0.021 | ||
| Htr2c | 5-hydroxytryptamine (serotonin) receptor 2C | 0.021 | ||
| Gnao1 | guanine nucleotide binding protein, alpha O | 0.021 | ||
| Chrna7 | cholinergic receptor, nicotinic, alpha polypeptide 7 | 0.021 | ||
| Cntn4 | contactin 4 | 0.020 | ||
| Gabra3 | gamma-aminobutyric acid (GABA) A receptor, subunit alpha 3 | 0.020 | Mouse | |
| En2 | engrailed 2 | 0.019 | ||
| Nxph2 | neurexophilin 2 | 0.019 | ||
| Sebox | SEBOX homeobox | 0.019 | ||
| Chrnb2 | cholinergic receptor, nicotinic, beta polypeptide 2 (neuronal) | 0.019 | ||
| Grin2a | glutamate receptor, ionotropic, NMDA2A (epsilon 1) | 0.019 | ||
| Gabra5 | gamma-aminobutyric acid (GABA) A receptor, subunit alpha 5 | 0.019 | Mouse | |
| Ppp2r2b | protein phosphatase 2 (formerly 2A), regulatory subunit B (PR 52), beta isoform | 0.019 | ||
| Stxbp5 | syntaxin binding protein 5 (tomosyn) | 0.018 | ||
| AI118078 | expressed sequence AI118078 | 0.018 | ||
| Pgr | progesterone receptor | 0.018 | ||
| Cnr1 | cannabinoid receptor 1 (brain) | 0.018 | ||
| D3Bwg0562e | DNA segment, Chr 3, Brigham & Women's Genetics 0562 expressed | 0.018 | ||
| Mas1 | MAS1 oncogene | 0.018 | ||
| Cacna2d3 | calcium channel, voltage-dependent, alpha2/delta subunit 3 | 0.018 | ||
| Ncam2 | neural cell adhesion molecule 2 | 0.018 | ||
| Nrsn1 | neurensin 1 | 0.017 | ||
| Htt | huntingtin | 0.017 | ||
| Kif5a | kinesin family member 5A | 0.017 | ||
| Cux2 | cut-like homeobox 2 | 0.017 | ||
| Elavl2 | ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B) | 0.016 | ||
| Kcna2 | potassium voltage-gated channel, shaker-related subfamily, member 2 | 0.016 | ||
| Sncb | synuclein, beta | 0.016 | ||
| St8sia3 | ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3 | 0.016 | ||
| Slc1a2 | solute carrier family 1 (glial high affinity glutamate transporter), member 2 | 0.016 | ||
| Erbb4 | v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian) | 0.016 | ||
| Nap1l2 | nucleosome assembly protein 1-like 2 | 0.015 | ||
| Sva | seminal vesicle antigen | 0.015 | ||
| Ptprn | protein tyrosine phosphatase, receptor type, N | 0.015 | ||
| Vsnl1 | visinin-like 1 | 0.015 | ||
| Invs | inversin | 0.015 | ||
| Chrm1 | cholinergic receptor, muscarinic 1, CNS | 0.015 | ||
| Syt3 | synaptotagmin III | 0.015 | Mouse | |
| Thrb | thyroid hormone receptor beta | 0.015 | ||
| Fgf12 | fibroblast growth factor 12 | 0.015 | ||
| Npcd | neuronal pentraxin chromo domain | 0.015 | ||
| Rasgrf2 | RAS protein-specific guanine nucleotide-releasing factor 2 | 0.015 | ||
| Kcnu1 | potassium channel, subfamily U, member 1 | 0.015 | ||
| 4930524B15Rik | RIKEN cDNA 4930524B15 gene | 0.015 | ||
| Epha5 | Eph receptor A5 | 0.015 | ||
| Ptprn2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | 0.014 | ||
| Atp2b2 | ATPase, Ca++ transporting, plasma membrane 2 | 0.014 | ||
| Elavl4 | ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D) | 0.014 | ||
| Kif5c | kinesin family member 5C | 0.014 | ||
| Arnt2 | aryl hydrocarbon receptor nuclear translocator 2 | 0.014 | ||
| Fgf14 | fibroblast growth factor 14 | 0.014 | ||
| Abcb9 | ATP-binding cassette, sub-family B (MDR/TAP), member 9 | 0.014 | ||
| Htr1d | 5-hydroxytryptamine (serotonin) receptor 1D | 0.014 | ||
| Cplx2 | complexin 2 | 0.014 | ||
| Syt1 | synaptotagmin I | 0.014 | Mouse | |
| Trhr | thyrotropin releasing hormone receptor | 0.014 | ||
| Nodal | nodal | 0.014 | ||
| Cacna1a | calcium channel, voltage-dependent, P/Q type, alpha 1A subunit | 0.014 | ||
| Grin2c | glutamate receptor, ionotropic, NMDA2C (epsilon 3) | 0.013 | ||
| Stxbp1 | syntaxin binding protein 1 | 0.013 | ||
| Ccdc39 | coiled-coil domain containing 39 | 0.013 | ||
| Zic3 | zinc finger protein of the cerebellum 3 | 0.013 | ||
| Myt1 | myelin transcription factor 1 | 0.013 | ||
| Trpc4 | transient receptor potential cation channel, subfamily C, member 4 | 0.013 | Mouse | |
| Pde1c | phosphodiesterase 1C | 0.013 | ||
| Cacnb2 | calcium channel, voltage-dependent, beta 2 subunit | 0.013 | ||
| Tmem146 | transmembrane protein 146 | 0.013 | ||
| Celf4 | CUGBP, Elav-like family member 4 | 0.013 | ||
| Htr4 | 5 hydroxytryptamine (serotonin) receptor 4 | 0.012 | ||
| Prox1 | prospero-related homeobox 1 | 0.012 | ||
| Bcl7a | B-cell CLL/lymphoma 7A | 0.012 | ||
| Mmp16 | matrix metallopeptidase 16 | 0.012 | ||
| Scn1a | sodium channel, voltage-gated, type I, alpha | 0.012 | ||
| Cacna1e | calcium channel, voltage-dependent, R type, alpha 1E subunit | 0.012 | ||
| Slc4a8 | solute carrier family 4 (anion exchanger), member 8 | 0.012 | ||
| Neurod1 | neurogenic differentiation 1 | 0.012 | ||
| Apc2 | adenomatosis polyposis coli 2 | 0.012 | ||
| Itga3 | integrin alpha 3 | 0.012 | ||
| Dazl | deleted in azoospermia-like | 0.012 | ||
| Vip | vasoactive intestinal polypeptide | 0.012 | ||
| Pde1a | phosphodiesterase 1A, calmodulin-dependent | 0.012 | ||
| Vhl | von Hippel-Lindau tumor suppressor | 0.012 | ||
| Cntnap1 | contactin associated protein-like 1 | 0.012 | ||
| Cx3cl1 | chemokine (C-X3-C motif) ligand 1 | 0.011 | ||
| Kcnj6 | potassium inwardly-rectifying channel, subfamily J, member 6 | 0.011 | ||
| Mmp24 | matrix metallopeptidase 24 | 0.011 | ||
| Gfra2 | glial cell line derived neurotrophic factor family receptor alpha 2 | 0.011 | ||
| Pclo | piccolo (presynaptic cytomatrix protein) | 0.011 | ||
| Npas2 | neuronal PAS domain protein 2 | 0.011 | ||
| Cntn3 | contactin 3 | 0.011 | ||
| Inpp5d | inositol polyphosphate-5-phosphatase D | 0.011 | ||
| Ggt7 | gamma-glutamyltransferase 7 | 0.011 | ||
| Hpcal4 | hippocalcin-like 4 | 0.011 | ||
| Pcsk1n | proprotein convertase subtilisin/kexin type 1 inhibitor | 0.011 | ||
| Stac | src homology three (SH3) and cysteine rich domain | 0.011 | ||
| Kcnj5 | potassium inwardly-rectifying channel, subfamily J, member 5 | 0.011 | ||
| Nefh | neurofilament, heavy polypeptide | 0.011 | ||
| Camk2a | calcium/calmodulin-dependent protein kinase II alpha | 0.011 | ||
| Btg4 | B-cell translocation gene 4 | 0.011 | ||
| Zfpm2 | zinc finger protein, multitype 2 | 0.011 | ||
| Elavl3 | ELAV (embryonic lethal, abnormal vision, Drosophila)-like 3 (Hu antigen C) | 0.011 | ||
| Dlg4 | discs, large homolog 4 (Drosophila) | 0.011 | ||
| Cacng7 | calcium channel, voltage-dependent, gamma subunit 7 | 0.011 | ||
| Rasgrp1 | RAS guanyl releasing protein 1 | 0.011 | ||
| Snn | stannin | 0.011 | ||
| Dync1i1 | dynein cytoplasmic 1 intermediate chain 1 | 0.011 | ||
| Mapk10 | mitogen-activated protein kinase 10 | 0.011 | ||
| Tub | tubby candidate gene | 0.011 | ||
| Epor | erythropoietin receptor | 0.011 | ||
| Trpc1 | transient receptor potential cation channel, subfamily C, member 1 | 0.011 | Mouse | |
| Mgat3 | mannoside acetylglucosaminyltransferase 3 | 0.010 | ||
| Drd2 | dopamine receptor D2 | 0.010 | ||
| Pkd2 | polycystic kidney disease 2 | 0.010 | Mouse | |
| Lhx6 | LIM homeobox protein 6 | 0.010 | ||
| Nfe2l3 | nuclear factor, erythroid derived 2, like 3 | 0.010 | ||
| Odz1 | odd Oz/ten-m homolog 1 (Drosophila) | 0.010 | ||
| Otud7a | OTU domain containing 7A | 0.010 | ||
| Mobp | myelin-associated oligodendrocytic basic protein | 0.010 | ||
| Prkar1b | protein kinase, cAMP dependent regulatory, type I beta | 0.010 | ||
| Adam2 | a disintegrin and metallopeptidase domain 2 | 0.010 | ||
| Hrh1 | histamine receptor H1 | 0.010 | ||
| Prm3 | protamine 3 | 0.010 | ||
| Kcnj4 | potassium inwardly-rectifying channel, subfamily J, member 4 | 0.010 | ||
| Tcte1 | t-complex-associated testis expressed 1 | 0.010 | ||
| Sprr2k | small proline-rich protein 2K | 0.010 | ||
| Ptprr | protein tyrosine phosphatase, receptor type, R | 0.010 | ||
| C78859 | expressed sequence C78859 | 0.010 | ||
| Kcns2 | K+ voltage-gated channel, subfamily S, 2 | 0.010 | ||
| Resp18 | regulated endocrine-specific protein 18 | 0.010 | ||
| Pla2g2c | phospholipase A2, group IIC | 0.010 | ||
| Actl6b | actin-like 6B | 0.010 | ||
| Cntn1 | contactin 1 | 0.010 | ||
| Dtna | dystrobrevin alpha | 0.010 | ||
| Kdm5d | lysine (K)-specific demethylase 5D | 0.010 | ||
| Nell2 | NEL-like 2 (chicken) | 0.010 |