IMP

Process View

Mus musculus

6 genes annotated in mouse

lobar bronchus development

The biological process whose specific outcome is the progression of a lobar bronchus from an initial condition to its mature state. This process begins with the formation of the lobar bronchus and ends with the mature structure. The lobar bronchus is the major airway within the respiratory tree that starts by division of the principal bronchi on both sides and ends at the point of its own subdivision into tertiary or segmental bronchi.

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "lobar bronchus development"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "lobar bronchus development" (in gray)

Name	Description	Probability	Func Analog Organism
Hoxb5	homeobox B5	0.895	Mouse
Hoxa5	homeobox A5	0.777
Hoxc5	homeobox C5	0.751	Mouse
Hoxd9	homeobox D9	0.735
Hoxa10	homeobox A10	0.705
Hoxc8	homeobox C8	0.659	Mouse
Gdnf	glial cell line derived neurotrophic factor	0.550
Hoxc6	homeobox C6	0.527	Mouse
Wnt4	wingless-related MMTV integration site 4	0.527	Mouse
Gli2	GLI-Kruppel family member GLI2	0.497
Lhx1	LIM homeobox protein 1	0.492
Hoxb6	homeobox B6	0.485	Mouse
Hoxa4	homeobox A4	0.440	Mouse
Hoxa9	homeobox A9	0.433
Dkk1	dickkopf homolog 1 (Xenopus laevis)	0.404
Hoxb9	homeobox B9	0.380
Hoxb3	homeobox B3	0.354
Pax8	paired box gene 8	0.348
Twist2	twist homolog 2 (Drosophila)	0.333
Hoxd8	homeobox D8	0.320	Mouse
Wnt10b	wingless related MMTV integration site 10b	0.297	Mouse
Wt1	Wilms tumor 1 homolog	0.242
Hoxc9	homeobox C9	0.202
Hoxa11	homeobox A11	0.196
Wnt3a	wingless-related MMTV integration site 3A	0.189	Mouse
Hoxc4	homeobox C4	0.152	Mouse
Hoxd10	homeobox D10	0.129
Bnc1	basonuclin 1	0.125
Foxd2	forkhead box D2	0.119
Hoxd11	homeobox D11	0.118
Emid2	EMI domain containing 2	0.105
Hoxb8	homeobox B8	0.102	Mouse
Hoxb4	homeobox B4	0.094	Mouse
Hoxb7	homeobox B7	0.088	Mouse
Foxn1	forkhead box N1	0.080
Hsd11b2	hydroxysteroid 11-beta dehydrogenase 2	0.075
Bcl2	B-cell leukemia/lymphoma 2	0.068
Sim2	single-minded homolog 2 (Drosophila)	0.065
Ror2	receptor tyrosine kinase-like orphan receptor 2	0.062
Hoxd4	homeobox D4	0.059	Mouse
Slc34a2	solute carrier family 34 (sodium phosphate), member 2	0.057
Pcsk5	proprotein convertase subtilisin/kexin type 5	0.052
Cldn8	claudin 8	0.047
Hoxa7	homeobox A7	0.047	Mouse
Shh	sonic hedgehog	0.046
Ihh	Indian hedgehog	0.044
Wnt2b	wingless related MMTV integration site 2b	0.044	Mouse
Ptger1	prostaglandin E receptor 1 (subtype EP1)	0.041
Hoxa2	homeobox A2	0.041
En1	engrailed 1	0.040
Fgf10	fibroblast growth factor 10	0.039
Wnt6	wingless-related MMTV integration site 6	0.037	Mouse
Meox2	mesenchyme homeobox 2	0.037
Sox7	SRY-box containing gene 7	0.036
Hoxd3	homeobox D3	0.036
Foxf1a	forkhead box F1a	0.034
Zfp185	zinc finger protein 185	0.034
Cdh16	cadherin 16	0.034
Efna4	ephrin A4	0.033
Gli3	GLI-Kruppel family member GLI3	0.033
Foxp1	forkhead box P1	0.032
Pbx1	pre B-cell leukemia transcription factor 1	0.031
Col11a1	collagen, type XI, alpha 1	0.030
Rara	retinoic acid receptor, alpha	0.030
Gli1	GLI-Kruppel family member GLI1	0.029
Foxd1	forkhead box D1	0.028
Edn3	endothelin 3	0.028
Socs1	suppressor of cytokine signaling 1	0.027
Tbx2	T-box 2	0.026
Dkk2	dickkopf homolog 2 (Xenopus laevis)	0.025
Nr5a1	nuclear receptor subfamily 5, group A, member 1	0.025
Pax2	paired box gene 2	0.025
Fzd1	frizzled homolog 1 (Drosophila)	0.024
Zfp503	zinc finger protein 503	0.024
Zbtb16	zinc finger and BTB domain containing 16	0.024
T	brachyury	0.023
Rab25	RAB25, member RAS oncogene family	0.023
Fzd8	frizzled homolog 8 (Drosophila)	0.022
Foxp2	forkhead box P2	0.022	Mouse
Fzd10	frizzled homolog 10 (Drosophila)	0.022
Emx2	empty spiracles homolog 2 (Drosophila)	0.022
Hoxd1	homeobox D1	0.021
Foxf2	forkhead box F2	0.020
Hoxb2	homeobox B2	0.020
Tctex1d4	Tctex1 domain containing 4	0.020
Wnt1	wingless-related MMTV integration site 1	0.019	Mouse
U46068	cDNA sequence U46068	0.019
Pou3f3	POU domain, class 3, transcription factor 3	0.018
Zbtb7c	zinc finger and BTB domain containing 7C	0.018
Mlph	melanophilin	0.018
Tnfrsf11a	tumor necrosis factor receptor superfamily, member 11a	0.018
Nynrin	NYN domain and retroviral integrase containing	0.018
Slc22a12	solute carrier family 22 (organic anion/cation transporter), member 12	0.018
Sema5a	sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A	0.017
Ror1	receptor tyrosine kinase-like orphan receptor 1	0.017
Fgf18	fibroblast growth factor 18	0.017
Uncx	UNC homeobox	0.017
Krt14	keratin 14	0.017
Hoxb13	homeobox B13	0.017
Jak2	Janus kinase 2	0.016
Col4a4	collagen, type IV, alpha 4	0.016
Vax1	ventral anterior homeobox containing gene 1	0.016
Gjb4	gap junction protein, beta 4	0.016
Pou3f2	POU domain, class 3, transcription factor 2	0.016
Tcf21	transcription factor 21	0.016
Oit1	oncoprotein induced transcript 1	0.016
Tcfap2c	transcription factor AP-2, gamma	0.015
Psg17	pregnancy specific glycoprotein 17	0.015
Meis1	Meis homeobox 1	0.015
Nkx2-1	NK2 homeobox 1	0.015
Col4a3	collagen, type IV, alpha 3	0.015
Tbx15	T-box 15	0.015
Zfp771	zinc finger protein 771	0.015
Cldn4	claudin 4	0.015
Adra2a	adrenergic receptor, alpha 2a	0.015
Emid1	EMI domain containing 1	0.015
Grem1	gremlin 1	0.014
Mst1r	macrophage stimulating 1 receptor (c-met-related tyrosine kinase)	0.014
Guca2b	guanylate cyclase activator 2b (retina)	0.014
Miox	myo-inositol oxygenase	0.014
Kl	klotho	0.013
Ctf1	cardiotrophin 1	0.013
Galnt3	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 3	0.013
Lmx1a	LIM homeobox transcription factor 1 alpha	0.013
Six6	sine oculis-related homeobox 6 homolog (Drosophila)	0.013
Krt15	keratin 15	0.013
Fgf2	fibroblast growth factor 2	0.013
Tmprss2	transmembrane protease, serine 2	0.013
Atp2c2	ATPase, Ca++ transporting, type 2C, member 2	0.012
Gpr50	G-protein-coupled receptor 50	0.012
Fxyd2	FXYD domain-containing ion transport regulator 2	0.012
Rem1	rad and gem related GTP binding protein 1	0.012
Hnf1b	HNF1 homeobox B	0.012
Hmx3	H6 homeobox 3	0.012
Clic3	chloride intracellular channel 3	0.012
Hmga2	high mobility group AT-hook 2	0.011
Kcnmb1	potassium large conductance calcium-activated channel, subfamily M, beta member 1	0.011
Cdh3	cadherin 3	0.011
1600029D21Rik	RIKEN cDNA 1600029D21 gene	0.011
Neurog1	neurogenin 1	0.011
Bmp15	bone morphogenetic protein 15	0.011
Slc6a4	solute carrier family 6 (neurotransmitter transporter, serotonin), member 4	0.010
Map3k7	mitogen-activated protein kinase kinase kinase 7	0.010
Wnt10a	wingless related MMTV integration site 10a	0.010
Clcnka	chloride channel Ka	0.010