IMP

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Rattus norvegicus

15 genes annotated in rat

Multi-species View

positive regulation of heart contraction

GO:0045823

Any process that activates or increases the frequency, rate or extent of heart contraction.

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Known genes in the process in rat Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "positive regulation of heart contraction"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "positive regulation of heart contraction" (in gray)

Name	Description	Probability	Func Analog Organism
Slc6a3	solute carrier family 6 (neurotransmitter transporter, dopamine), member 3	0.753
Insrr	insulin receptor-related receptor	0.355
Chrna1	cholinergic receptor, nicotinic, alpha 1 (muscle)	0.230
P2rx3	purinergic receptor P2X, ligand-gated ion channel, 3	0.216
Lim2	lens intrinsic membrane protein 2	0.189
Htr6	5-hydroxytryptamine (serotonin) receptor 6	0.171
Htr2c	5-hydroxytryptamine (serotonin) receptor 2C	0.165
Scn10a	sodium channel, voltage-gated, type X, alpha subunit	0.155	Rat
Hspa8	heat shock protein 8	0.151
Fgf14	fibroblast growth factor 14	0.149
Hrh2	histamine receptor H 2	0.140	Rat
Dspp	dentin sialophosphoprotein	0.130
Hsph1	heat shock 105/110 protein 1	0.119
Trhr2	thyrotropin releasing hormone receptor 2	0.108
Ncan	neurocan	0.093
Ucn	urocortin	0.086
Fev	FEV (ETS oncogene family)	0.085
Celsr3	cadherin, EGF LAG seven-pass G-type receptor 3 (flamingo homolog, Drosophila)	0.084
Psp	parotid secretory protein	0.083
Kcnh7	potassium voltage-gated channel, subfamily H (eag-related), member 7	0.080
RGD1310262	hypothetical LOC304650	0.079
RGD1564327	similar to integrin alpha 8	0.078
Pgc	progastricsin (pepsinogen C)	0.078
Gpr12	G protein-coupled receptor 12	0.077
Grin2b	glutamate receptor, ionotropic, N-methyl D-aspartate 2B	0.077
Mc5r	melanocortin 5 receptor	0.076
Csf1	colony stimulating factor 1 (macrophage)	0.075
Ccbp2	chemokine binding protein 2	0.073
Cacnb1	calcium channel, voltage-dependent, beta 1 subunit	0.072
Slc18a2	solute carrier family 18 (vesicular monoamine), member 2	0.067
Notch3	Notch homolog 3 (Drosophila)	0.066
Gjd2	gap junction protein, delta 2	0.066
Hsd3b5	hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 5	0.066
Dlg4	discs, large homolog 4 (Drosophila)	0.065
Olr1082	olfactory receptor 1082	0.064
Cckar	cholecystokinin A receptor	0.063
Oprk1	opioid receptor, kappa 1	0.062
Chrna7	cholinergic receptor, nicotinic, alpha 7	0.062
Cd28	Cd28 molecule	0.062
Testin	testin gene	0.060
Crhbp	corticotropin releasing hormone binding protein	0.059
Chrnb3	cholinergic receptor, nicotinic, beta 3	0.059
Aqp5	aquaporin 5	0.058
Afap1	actin filament associated protein 1	0.058
Fgf16	fibroblast growth factor 16	0.057
Gfra2	GDNF family receptor alpha 2	0.057
Chrm5	cholinergic receptor, muscarinic 5	0.056
Syt8	synaptotagmin VIII	0.056
Pla2g5	phospholipase A2, group V	0.055
Omp	olfactory marker protein	0.054
Cd40lg	CD40 ligand	0.054
Ctsj	cathepsin J	0.054
Hspd1	heat shock protein 1 (chaperonin)	0.053
Eef2	eukaryotic translation elongation factor 2	0.053
Csrnp2	cysteine-serine-rich nuclear protein 2	0.053
Olr287	olfactory receptor 287	0.053
Slc6a7	solute carrier family 6 (neurotransmitter transporter, L-proline), member 7	0.051
Olr1500	olfactory receptor 1500	0.050
Teddm1	transmembrane epididymal protein 1	0.050
LOC100360919	Immunoglobulin lambda-like polypeptide 1-like	0.049
Slc8a2	solute carrier family 8 (sodium/calcium exchanger), member 2	0.046
Iapp	islet amyloid polypeptide	0.046
Fam83f	family with sequence similarity 83, member F	0.046
Sema6c	sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6C	0.045
Rin1	Ras and Rab interactor 1	0.044
Rho	rhodopsin	0.044
Glp1r	glucagon-like peptide 1 receptor	0.043
Syngap1	synaptic Ras GTPase activating protein 1 homolog (rat)	0.043
Slc7a3	solute carrier family 7 (cationic amino acid transporter, y+ system), member 3	0.043
Trpv6	transient receptor potential cation channel, subfamily V, member 6	0.043
Edn1	endothelin 1	0.042	Human
Folh1	folate hydrolase 1	0.042
Kalrn	kalirin, RhoGEF kinase	0.042
Mpp2	membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2)	0.042
Fgf7	fibroblast growth factor 7	0.041
Il4	interleukin 4	0.041
Gpr88	G-protein coupled receptor 88	0.040
Olr1641	olfactory receptor 1641	0.040
Tacr3	tachykinin receptor 3	0.039
Olr226	olfactory receptor 226	0.039
Scnn1a	sodium channel, nonvoltage-gated 1 alpha	0.039
Htr1d	5-hydroxytryptamine (serotonin) receptor 1D	0.038	Rat
Cntn3	contactin 3 (plasmacytoma associated)	0.038
Hrh3	histamine receptor H3	0.038
Kcnmb1	potassium large conductance calcium-activated channel, subfamily M, beta member 1	0.038
Cacna1a	calcium channel, voltage-dependent, P/Q type, alpha 1A subunit	0.038
Pmch	pro-melanin-concentrating hormone	0.038
Cntfr	ciliary neurotrophic factor receptor	0.038
Egr4	early growth response 4	0.037
Atp7b	ATPase, Cu++ transporting, beta polypeptide	0.037
Cnga1	cyclic nucleotide gated channel alpha 1	0.036
Gpr1	G protein-coupled receptor 1	0.036
Kcnj5	potassium inwardly-rectifying channel, subfamily J, member 5	0.036
Syn3	synapsin III	0.035
RGD1308165	similar to hypothetical protein MGC17337	0.035
Adamts13	ADAM metallopeptidase with thrombospondin type 1 motif, 13	0.034
Bcl2l10	BCL2-like 10 (apoptosis facilitator)	0.033
Fshb	follicle stimulating hormone, beta polypeptide	0.033
Trim47	tripartite motif-containing 47	0.033
LOC689154	hypothetical protein LOC689154	0.033
Gzmk	granzyme K	0.032
Slurp1	secreted Ly6/Plaur domain containing 1	0.031
Lipf	lipase, gastric	0.031
Dlx5	distal-less homeobox 5	0.030
Htr5b	5-hydroxytryptamine (serotonin) receptor 5B	0.030	Rat
Olr1078	olfactory receptor 1078	0.030
Spock2	sparc/osteonectin, cwcv and kazal-like domains proteoglycan 2	0.030
Cacna1c	calcium channel, voltage-dependent, L type, alpha 1C subunit	0.030
Ppy	pancreatic polypeptide	0.030
RGD1565927	similar to 4631422O05Rik protein	0.030
Grik3	glutamate receptor, ionotropic, kainate 3	0.029
Rgs9	regulator of G-protein signaling 9	0.029
Gng7	guanine nucleotide binding protein (G protein), gamma 7	0.029
Il9r	interleukin 9 receptor	0.029
Cpne9	copine family member IX	0.029
Slc7a12	solute carrier family 7 (cationic amino acid transporter, y+ system), member 12	0.029
Cdh6	cadherin 6	0.028
Sult1d1	sulfotransferase family 1D, member 1	0.028
Nxph4	neurexophilin 4	0.028
Dcc	deleted in colorectal carcinoma	0.028
Vip	vasoactive intestinal peptide	0.027
Slc28a1	solute carrier family 28 (sodium-coupled nucleoside transporter), member 1	0.027
Pex5l	peroxisomal biogenesis factor 5-like	0.027
Klf6	Kruppel-like factor 6	0.027
Grm1	glutamate receptor, metabotropic 1	0.027
Gja3	gap junction protein, alpha 3	0.027
Mrgprf	MAS-related GPR, member F	0.026
Slc6a11	solute carrier family 6 (neurotransmitter transporter, GABA), member 11	0.026
Lep	leptin	0.026
Chrna4	cholinergic receptor, nicotinic, alpha 4	0.026
Cacng4	calcium channel, voltage-dependent, gamma subunit 4	0.025
Tnp2	transition protein 2	0.025
Lalba	lactalbumin, alpha	0.025
Galr1	galanin receptor 1	0.025
Unc13c	unc-13 homolog C (C. elegans)	0.025
Fos	FBJ osteosarcoma oncogene	0.024
Prlh	prolactin releasing hormone	0.024
Grp	gastrin releasing peptide	0.024
Wisp2	WNT1 inducible signaling pathway protein 2	0.024	Rat
Uts2	urotensin 2	0.024
Unc45b	unc-45 homolog B (C. elegans)	0.024
Mag	myelin-associated glycoprotein	0.024
Ghrl	ghrelin/obestatin prepropeptide	0.024
Grem1	gremlin 1, cysteine knot superfamily, homolog (Xenopus laevis)	0.024
Lrrc4b	leucine rich repeat containing 4B	0.024
Cyp4a8	cytochrome P450, family 4, subfamily a, polypeptide 8	0.024
Cyp27b1	cytochrome P450, family 27, subfamily b, polypeptide 1	0.024
RGD1565168	similar to RAP2A, member of RAS oncogene family	0.024
Myog	myogenin	0.023
Gpr135	G protein-coupled receptor 135	0.023
Crtc3	CREB regulated transcription coactivator 3	0.023
Megf6	multiple EGF-like-domains 6	0.023
Prl2a1	Prolactin family 2, subfamily a, member 1	0.023
Kiss1r	KISS1 receptor	0.023
Uncx	UNC homeobox	0.023
Dmrta1	DMRT-like family A1	0.023
N5	DNA binding protein N5	0.023
Htr3a	5-hydroxytryptamine (serotonin) receptor 3a	0.022
Rims1	regulating synaptic membrane exocytosis 1	0.022
Kcnn3	potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3	0.022
Robo1	roundabout homolog 1 (Drosophila)	0.022
Ly6g6e	lymphocyte antigen 6 complex, locus G6E	0.021
Stip1	stress-induced phosphoprotein 1	0.021
Tnfsf4	tumor necrosis factor (ligand) superfamily, member 4	0.021
Hes3	hairy and enhancer of split 3 (Drosophila)	0.021
Slc5a5	solute carrier family 5 (sodium iodide symporter), member 5	0.021
Kcnh6	potassium voltage-gated channel, subfamily H (eag-related), member 6	0.021
Prkcg	protein kinase C, gamma	0.021
Dusp4	dual specificity phosphatase 4	0.021
Hoxa1	homeo box A1	0.020
Chrnb1	cholinergic receptor, nicotinic, beta 1 (muscle)	0.020
Ifnb1	interferon beta 1, fibroblast	0.020
Tacr1	tachykinin receptor 1	0.020	Rat
Apoa4	apolipoprotein A-IV	0.020
Foxe3	forkhead box E3	0.020
Kcng2	potassium voltage-gated channel, subfamily G, member 2	0.019
Grm8	glutamate receptor, metabotropic 8	0.019
Tff1	trefoil factor 1	0.019
Agtr1a	angiotensin II receptor, type 1a	0.019
Clcnka	chloride channel Ka	0.019
Hpca	hippocalcin	0.019
Necab1	N-terminal EF-hand calcium binding protein 1	0.019
Prm2	protamine 2	0.019
Cxcr5	chemokine (C-X-C motif) receptor 5	0.019
Chrm2	cholinergic receptor, muscarinic 2	0.019
Gabre	gamma-aminobutyric acid (GABA) A receptor, epsilon	0.019
Col8a1	collagen, type VIII, alpha 1	0.019
Rgs14	regulator of G-protein signaling 14	0.019
Nrl	neural retina leucine zipper	0.018
Zp1	zona pellucida glycoprotein 1 (sperm receptor)	0.018
Fbxo10	F-box protein 10	0.018
Prl3b1	Prolactin family 3, subfamily b, member 1	0.018
Slc18a3	solute carrier family 18 (vesicular acetylcholine), member 3	0.018
Scnn1b	sodium channel, nonvoltage-gated 1, beta	0.018
Cmtm2a	CKLF-like MARVEL transmembrane domain containing 2A	0.018
Mdga1	MAM domain containing glycosylphosphatidylinositol anchor 1	0.017
Mchr1	melanin-concentrating hormone receptor 1	0.017
Myoc	myocilin	0.017
Cnga2	cyclic nucleotide gated channel alpha 2	0.017
Defb22	defensin beta 22	0.017
Olr416	olfactory receptor 416	0.017
Pde1b	phosphodiesterase 1B, calmodulin-dependent	0.017
Syt7	synaptotagmin VII	0.017
Hcrtr2	hypocretin (orexin) receptor 2	0.017	Rat
Fgf10	fibroblast growth factor 10	0.017
Hoxa4	homeo box A4	0.017
Pde1c	phosphodiesterase 1C	0.017
Colq	collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase	0.017
Mapk3	mitogen activated protein kinase 3	0.017
Scnn1g	sodium channel, nonvoltage-gated 1, gamma	0.017
Il11	interleukin 11	0.017
Ica1l	islet cell autoantigen 1-like	0.016
Olfml2b	olfactomedin-like 2B	0.016
Ms4a2	membrane-spanning 4-domains, subfamily A, member 2 (Fc fragment of IgE, high affinity I, receptor for; beta polypeptide)	0.016
Il17re	interleukin 17 receptor E	0.016
Cyss	cystatin S	0.016
Vdr	vitamin D (1,25- dihydroxyvitamin D3) receptor	0.016
Grm5	glutamate receptor, metabotropic 5	0.016
Slc14a2	solute carrier family 14 (urea transporter), member 2	0.016
Pax8	paired box 8	0.016
Adra1a	adrenergic, alpha-1A-, receptor	0.016
Synpo	synaptopodin	0.016
Shbg	sex hormone binding globulin	0.016
Smgb	neonatal submandibular gland protein B	0.016
Cyp21a1	cytochrome P450, family 21, subfamily a, polypeptide 1	0.015
Htr7	5-hydroxytryptamine (serotonin) receptor 7	0.015	Rat
Ngf	nerve growth factor (beta polypeptide)	0.015
Cox4i2	cytochrome c oxidase subunit IV isoform 2	0.015
Accn2	amiloride-sensitive cation channel 2, neuronal	0.015
Trpc4	transient receptor potential cation channel, subfamily C, member 4	0.015
Gpr26	G protein-coupled receptor 26	0.015
Acr	acrosin	0.015
Mfrp	membrane frizzled-related protein	0.015
Gabrb3	gamma-aminobutyric acid (GABA) A receptor, beta 3	0.015
Wap	whey acidic protein	0.015
RGD1564664	similar to LOC387763 protein	0.015
Ghrh	growth hormone releasing hormone	0.015
Wbp5	WW domain binding protein 5	0.014
Galnt5	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 5 (GalNAc-T5)	0.014
Adam5	a disintegrin and metallopeptidase domain 5	0.014
Chst3	carbohydrate (chondroitin 6) sulfotransferase 3	0.014
Foxd4	forkhead box D4	0.014
Prl	prolactin	0.014
Grm2	glutamate receptor, metabotropic 2	0.014
Tacr2	tachykinin receptor 2	0.014
Itgb7	integrin, beta 7	0.014
Glp2r	glucagon-like peptide 2 receptor	0.014	Rat
Vcsa1	variable coding sequence A1	0.014
Nfasc	neurofascin	0.014
Krt34	keratin 34	0.014
Abcc9	ATP-binding cassette, subfamily C (CFTR/MRP), member 9	0.014
Olr1413	olfactory receptor 1413	0.014
Hcrtr1	hypocretin (orexin) receptor 1	0.013	Rat
RGD1565859	RGD1565859	0.013
Pnoc	prepronociceptin	0.013
Olr1361	olfactory receptor 1361	0.013
Kcnj4	potassium inwardly-rectifying channel, subfamily J, member 4	0.013
Atp2b2	ATPase, Ca++ transporting, plasma membrane 2	0.013
Npr3	natriuretic peptide receptor C/guanylate cyclase C (atrionatriuretic peptide receptor C)	0.013
Nkx2-5	NK2 transcription factor related, locus 5 (Drosophila)	0.013	Mouse
Nkx6-1	NK6 homeobox 1	0.013
Dhrs9	dehydrogenase/reductase (SDR family) member 9	0.013
Prok1	prokineticin 1	0.013
Col10a1	collagen, type X, alpha 1	0.013
Gabra5	gamma-aminobutyric acid (GABA) A receptor, alpha 5	0.013
Foxg1	forkhead box G1	0.013
Cbln2	cerebellin 2 precursor	0.013
P2rx1	purinergic receptor P2X, ligand-gated ion channel, 1	0.013
Nrxn3	neurexin 3	0.013
Dgkb	diacylglycerol kinase, beta	0.013
Egr3	early growth response 3	0.012
Mal	mal, T-cell differentiation protein	0.012
Pitx3	paired-like homeodomain 3	0.012
Gapdh	glyceraldehyde-3-phosphate dehydrogenase	0.012
Capza3	capping protein (actin filament) muscle Z-line, alpha 3	0.012
Olr1523	olfactory receptor 1523	0.012
Dusp1	dual specificity phosphatase 1	0.012
Crygb	crystallin, gamma B	0.012
Kcnq3	potassium voltage-gated channel, KQT-like subfamily, member 3	0.012
Hcrt	hypocretin	0.012
Kcng1	potassium voltage-gated channel, subfamily G, member 1	0.012
Fxyd4	FXYD domain-containing ion transport regulator 4	0.012
Cpxm2	carboxypeptidase X (M14 family), member 2	0.012
Mustn1	musculoskeletal, embryonic nuclear protein 1	0.012
Nptxr	neuronal pentraxin receptor	0.012
Pou3f3	POU class 3 homeobox 3	0.012
Asph	aspartate-beta-hydroxylase	0.012
Cryge	crystallin, gamma E	0.012
Smr3a	submaxillary gland androgen regulated protein 3A	0.012
Ncl	nucleolin	0.012
Phyhip	phytanoyl-CoA 2-hydroxylase interacting protein	0.012
Brunol4	bruno-like 4, RNA binding protein (Drosophila)	0.012
Lif	leukemia inhibitory factor	0.011
Ppp2r2c	protein phosphatase 2 (formerly 2A), regulatory subunit B, gamma isoform	0.011
Npffr1	neuropeptide FF receptor 1	0.011	Rat
Vom2r18	vomeronasal 2 receptor, 18	0.011
Gfi1b	growth factor independent 1B transcription repressor	0.011
Crx	cone-rod homeobox	0.011
Crisp1	cysteine-rich secretory protein 1	0.011
Accn3	amiloride-sensitive cation channel 3	0.011
Slc9a4	solute carrier family 9 (sodium/hydrogen exchanger), member 4	0.011
Semg1	semenogelin I	0.011
Hmga2	high mobility group AT-hook 2	0.011
Cnksr2	connector enhancer of kinase suppressor of Ras 2	0.011
Cacng6	calcium channel, voltage-dependent, gamma subunit 6	0.011
Apba2	amyloid beta (A4) precursor protein-binding, family A, member 2	0.011
Gucy2e	guanylate cyclase 2E	0.011
Epn1	Epsin 1	0.011
Ednra	endothelin receptor type A	0.011
Si	sucrase-isomaltase (alpha-glucosidase)	0.011
Drd2	dopamine receptor D2	0.011
Atp1b1	ATPase, Na+/K+ transporting, beta 1 polypeptide	0.011
Rxrg	retinoid X receptor gamma	0.011
Nrg1	neuregulin 1	0.011
Dlgap1	discs, large (Drosophila) homolog-associated protein 1	0.011
Arnt2	aryl hydrocarbon receptor nuclear translocator 2	0.011
Trpm1	transient receptor potential cation channel, subfamily M, member 1	0.011
Reg3a	regenerating islet-derived 3 alpha	0.011
Omd	osteomodulin	0.011
Taok2	TAO kinase 2	0.011
Cntn5	contactin 5	0.010
Scn3a	sodium channel, voltage-gated, type III, alpha	0.010
Ton	tonin	0.010
Phox2a	paired-like homeobox 2a	0.010
RGD1565997	similar to 4931417G12Rik protein	0.010
Cyr61	cysteine-rich, angiogenic inducer, 61	0.010	Rat
Erbb4	v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)	0.010
Elavl4	ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)	0.010
Phkg1	phosphorylase kinase, gamma 1	0.010
Pax6	paired box 6	0.010
Syn1	synapsin I	0.010
Glra2	glycine receptor, alpha 2	0.010
LOC286980	putative pheromone receptor (Go-VN13B)	0.010
Hand2	heart and neural crest derivatives expressed 2	0.010