IMP
Process View
endothelium development
The process whose specific outcome is the progression of an endothelium over time, from its formation to the mature structure. Endothelium refers to the layer of cells lining blood vessels, lymphatics, the heart, and serous cavities, and is derived from bone marrow or mesoderm. Corneal endothelium is a special case, derived from neural crest cells.
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In addition to gene-name show these genes:
Click on a gene's description to view its network relationships with genes known to be involved in "endothelium development"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| Emp1 | epithelial membrane protein 1 | 0.440 | ||
| Gnai3 | guanine nucleotide binding protein (G protein), alpha inhibiting 3 | 0.416 | ||
| Litaf | lipopolysaccharide-induced TNF factor | 0.232 | ||
| Lamc1 | laminin, gamma 1 | 0.197 | ||
| Pecam1 | platelet/endothelial cell adhesion molecule 1 | 0.189 | ||
| Nos3 | nitric oxide synthase 3, endothelial cell | 0.155 | ||
| Cdh5 | cadherin 5 | 0.141 | ||
| Smad7 | SMAD family member 7 | 0.128 | ||
| Itgb1 | integrin, beta 1 | 0.108 | ||
| Flt1 | FMS-related tyrosine kinase 1 | 0.090 | ||
| Itga6 | integrin, alpha 6 | 0.089 | ||
| Tgfbr2 | transforming growth factor, beta receptor II | 0.078 | Rat | |
| Id3 | inhibitor of DNA binding 3 | 0.074 | ||
| Myh9 | myosin, heavy chain 9, non-muscle | 0.073 | ||
| Gper | G protein-coupled estrogen receptor 1 | 0.070 | ||
| Col12a1 | collagen, type XII, alpha 1 | 0.067 | ||
| Notch3 | Notch homolog 3 (Drosophila) | 0.066 | Rat | |
| Arf6 | ADP-ribosylation factor 6 | 0.065 | ||
| Utrn | utrophin | 0.058 | ||
| Pdk4 | pyruvate dehydrogenase kinase, isozyme 4 | 0.056 | ||
| Nek9 | NIMA (never in mitosis gene a)- related kinase 9 | 0.054 | ||
| Arpc5 | actin related protein 2/3 complex, subunit 5 | 0.053 | ||
| Nfib | nuclear factor I/B | 0.052 | ||
| Trhr2 | thyrotropin releasing hormone receptor 2 | 0.051 | ||
| Nfe2l2 | nuclear factor, erythroid derived 2, like 2 | 0.051 | ||
| LOC100360986 | mCG1035404-like | 0.047 | ||
| Anxa1 | annexin A1 | 0.045 | ||
| Cald1 | caldesmon 1 | 0.041 | ||
| Tie1 | tyrosine kinase with immunoglobulin-like and EGF-like domains 1 | 0.037 | ||
| Myo1c | myosin IC | 0.037 | ||
| Nr4a2 | nuclear receptor subfamily 4, group A, member 2 | 0.036 | ||
| Prkch | protein kinase C, eta | 0.036 | ||
| Timp3 | TIMP metallopeptidase inhibitor 3 | 0.035 | ||
| Sdcbp | syndecan binding protein | 0.035 | ||
| Plat | plasminogen activator, tissue | 0.034 | ||
| Gja5 | gap junction protein, alpha 5 | 0.033 | ||
| Gabrp | gamma-aminobutyric acid (GABA-A) receptor, pi | 0.032 | ||
| Esam | endothelial cell adhesion molecule | 0.032 | ||
| Mcam | melanoma cell adhesion molecule | 0.030 | ||
| Tgfbr3 | transforming growth factor, beta receptor III | 0.030 | ||
| Rest | RE1-silencing transcription factor | 0.030 | ||
| Lims1 | LIM and senescent cell antigen-like domains 1 | 0.029 | ||
| Igfbp5 | insulin-like growth factor binding protein 5 | 0.029 | ||
| Map4k2 | mitogen activated protein kinase kinase kinase kinase 2 | 0.028 | ||
| Bcl2 | B-cell CLL/lymphoma 2 | 0.027 | ||
| Cdkn2b | cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4) | 0.027 | ||
| Igf2bp2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.027 | ||
| Gpr116 | G protein-coupled receptor 116 | 0.027 | ||
| Casq2 | calsequestrin 2 (cardiac muscle) | 0.026 | ||
| Pcna | proliferating cell nuclear antigen | 0.025 | ||
| Dmgdh | dimethylglycine dehydrogenase | 0.025 | ||
| Rac1 | ras-related C3 botulinum toxin substrate 1 | 0.024 | ||
| Ednrb | endothelin receptor type B | 0.024 | ||
| Mobkl1b | MOB1, Mps One Binder kinase activator-like 1B (yeast) | 0.022 | ||
| Itpr2 | inositol 1,4,5-triphosphate receptor, type 2 | 0.022 | ||
| Col4a1 | collagen, type IV, alpha 1 | 0.022 | ||
| Pdlim5 | PDZ and LIM domain 5 | 0.021 | ||
| Sox7 | SRY (sex determining region Y)-box 7 | 0.020 | ||
| Mmp14 | matrix metallopeptidase 14 (membrane-inserted) | 0.020 | ||
| Gfi1 | growth factor independent 1 transcription repressor | 0.020 | ||
| Tln1 | talin 1 | 0.020 | ||
| Prss22 | protease, serine, 22 | 0.020 | ||
| Cgm4 | carcinoembryonic antigen gene family 4 | 0.019 | ||
| Mospd4 | motile sperm domain containing 4 | 0.019 | ||
| Tff2 | trefoil factor 2 | 0.019 | ||
| Notch4 | Notch homolog 4 (Drosophila) | 0.019 | ||
| Flna | filamin A, alpha | 0.018 | ||
| Magi2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.018 | ||
| Pvrl4 | poliovirus receptor-related 4 | 0.018 | ||
| Fgf6 | fibroblast growth factor 6 | 0.018 | ||
| Cyp3a18 | cytochrome P450, family 3, subfamily a, polypeptide 18 | 0.018 | ||
| Ampd3 | adenosine monophosphate deaminase 3 | 0.017 | ||
| Gse1 | genetic suppressor element 1 | 0.017 | ||
| Camkk2 | calcium/calmodulin-dependent protein kinase kinase 2, beta | 0.017 | ||
| Foxd3 | forkhead box D3 | 0.017 | ||
| Spock2 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan 2 | 0.017 | ||
| Slc12a1 | solute carrier family 12 (sodium/potassium/chloride transporters), member 1 | 0.017 | ||
| Sag | S-antigen; retina and pineal gland (arrestin) | 0.016 | ||
| Slit3 | slit homolog 3 (Drosophila) | 0.016 | ||
| Neurod2 | neurogenic differentiation 2 | 0.016 | ||
| Kcnj8 | potassium inwardly-rectifying channel, subfamily J, member 8 | 0.016 | ||
| Foxo1 | forkhead box O1 | 0.016 | ||
| Snap23 | synaptosomal-associated protein 23 | 0.016 | ||
| Pmp22 | peripheral myelin protein 22 | 0.016 | ||
| Sox13 | SRY (sex determining region Y)-box 13 | 0.016 | ||
| Pparg | peroxisome proliferator-activated receptor gamma | 0.015 | ||
| LOC100364212 | heterogeneous nuclear ribonucleoprotein K-like | 0.015 | ||
| Ppap2a | phosphatidic acid phosphatase type 2A | 0.015 | ||
| Serpine2 | serine (or cysteine) peptidase inhibitor, clade E, member 2 | 0.015 | ||
| Slco2a1 | solute carrier organic anion transporter family, member 2a1 | 0.015 | ||
| Kcnq3 | potassium voltage-gated channel, KQT-like subfamily, member 3 | 0.015 | ||
| Klf2 | Kruppel-like factor 2 (lung) | 0.015 | ||
| Gata2 | GATA binding protein 2 | 0.014 | ||
| Hcrtr1 | hypocretin (orexin) receptor 1 | 0.014 | ||
| Entpd1 | ectonucleoside triphosphate diphosphohydrolase 1 | 0.014 | ||
| Myo1e | myosin IE | 0.014 | ||
| F13a1 | coagulation factor XIII, A1 polypeptide | 0.014 | ||
| Rgs4 | regulator of G-protein signaling 4 | 0.014 | ||
| Asmt | acetylserotonin O-methyltransferase | 0.014 | ||
| Vcsa2 | variable coding sequence A2 | 0.014 | ||
| Mia | melanoma inhibitory activity | 0.013 | ||
| Ece1 | endothelin converting enzyme 1 | 0.013 | ||
| Atp7b | ATPase, Cu++ transporting, beta polypeptide | 0.013 | ||
| Ahnak | AHNAK nucleoprotein | 0.013 | ||
| Olr837 | olfactory receptor 837 | 0.013 | ||
| Svs4 | seminal vesicle secretory protein 4 | 0.013 | ||
| Fgfr2 | fibroblast growth factor receptor 2 | 0.013 | ||
| Rap1a | RAP1A, member of RAS oncogene family | 0.013 | Human | |
| Tcf4 | transcription factor 4 | 0.013 | ||
| Unc5b | unc-5 homolog B (C. elegans) | 0.012 | ||
| Fam70b | family with sequence similarity 70, member B | 0.012 | ||
| LOC494499 | LOC494499 protein | 0.012 | ||
| Cyp27b1 | cytochrome P450, family 27, subfamily b, polypeptide 1 | 0.012 | ||
| Celsr2 | cadherin, EGF LAG seven-pass G-type receptor 2 (flamingo homolog, Drosophila) | 0.012 | ||
| Enpep | glutamyl aminopeptidase | 0.012 | ||
| Stk17b | serine/threonine kinase 17b | 0.012 | ||
| Socs2 | suppressor of cytokine signaling 2 | 0.012 | ||
| Zfp36l1 | zinc finger protein 36, C3H type-like 1 | 0.011 | ||
| Slc2a13 | solute carrier family 2 (facilitated glucose transporter), member 13 | 0.011 | ||
| Slc6a20 | solute carrier family 6 (proline IMINO transporter), member 20 | 0.011 | ||
| Soat1 | sterol O-acyltransferase 1 | 0.011 | ||
| Cyp4a3 | cytochrome P450, family 4, subfamily a, polypeptide 3 | 0.011 | ||
| Scn3a | sodium channel, voltage-gated, type III, alpha | 0.011 | ||
| Calcrl | calcitonin receptor-like | 0.011 | ||
| Mt1a | metallothionein 1a | 0.011 | ||
| Nrg1 | neuregulin 1 | 0.011 | Human | |
| Lmna | lamin A | 0.011 | ||
| Grm6 | glutamate receptor, metabotropic 6 | 0.011 | ||
| Cd38 | CD38 molecule | 0.011 | ||
| Dchs1 | dachsous 1 (Drosophila) | 0.011 | ||
| Ebf1 | early B-cell factor 1 | 0.011 | ||
| Cnn3 | calponin 3, acidic | 0.011 | ||
| Aqp4 | aquaporin 4 | 0.010 | ||
| RGD1563224 | similar to 4930438D12Rik protein | 0.010 | ||
| Ctsl1 | cathepsin L1 | 0.010 | ||
| Gja1 | gap junction protein, alpha 1 | 0.010 | ||
| Cdk2 | cyclin dependent kinase 2 | 0.010 | ||
| Fgf7 | fibroblast growth factor 7 | 0.010 | ||
| Purb | purine rich element binding protein B | 0.010 |