IMP

Process View

Rattus norvegicus

13 genes annotated in rat

tumor necrosis factor superfamily cytokine production

The appearance of any member of the TNF superfamily due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.

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Known genes in the process in rat Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "tumor necrosis factor superfamily cytokine production"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "tumor necrosis factor superfamily cytokine production" (in gray)

Name	Description	Probability	Func Analog Organism
Ccl7	chemokine (C-C motif) ligand 7	0.550	Rat
Ccl2	chemokine (C-C motif) ligand 2	0.419
Cd14	CD14 molecule	0.248	Human
Il1b	interleukin 1 beta	0.218
Stat3	signal transducer and activator of transcription 3	0.207
Cxcl1	chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)	0.191
Icam1	intercellular adhesion molecule 1	0.177
Tnfrsf1a	tumor necrosis factor receptor superfamily, member 1a	0.167
Litaf	lipopolysaccharide-induced TNF factor	0.161
Cd44	Cd44 molecule	0.151
Igsf6	immunoglobulin superfamily, member 6	0.148
Pla2g2a	phospholipase A2, group IIA (platelets, synovial fluid)	0.148
Cxcl10	chemokine (C-X-C motif) ligand 10	0.126
Ccl3	chemokine (C-C motif) ligand 3	0.113	Rat
Myd88	myeloid differentiation primary response gene 88	0.099	Mouse
Mmp12	matrix metallopeptidase 12	0.098
Timp1	TIMP metallopeptidase inhibitor 1	0.094
Cxcl2	chemokine (C-X-C motif) ligand 2	0.084
Lgals3	lectin, galactoside-binding, soluble, 3	0.083
S100a6	S100 calcium binding protein A6	0.081
Klrd1	killer cell lectin-like receptor, subfamily D, member 1	0.060
Ccr2	chemokine (C-C motif) receptor 2	0.051
Ifi204	interferon activated gene 204	0.049
Ccl4	chemokine (C-C motif) ligand 4	0.048
Ier3	immediate early response 3	0.048
Olr1	oxidized low density lipoprotein (lectin-like) receptor 1	0.045
C5ar1	complement component 5a receptor 1	0.044
Il6	interleukin 6	0.042
Rab32	RAB32, member RAS oncogene family	0.040
Il1r2	interleukin 1 receptor, type II	0.039
Hmox1	heme oxygenase (decycling) 1	0.039
Ltbr	lymphotoxin beta receptor (TNFR superfamily, member 3)	0.038
Tlr2	toll-like receptor 2	0.037
Itgam	integrin, alpha M	0.035
Rgs1	regulator of G-protein signaling 1	0.033
Xdh	xanthine dehydrogenase	0.031
St8sia4	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4	0.031
Junb	jun B proto-oncogene	0.030
Cebpb	CCAAT/enhancer binding protein (C/EBP), beta	0.030
Il2rg	interleukin 2 receptor, gamma	0.029
Cdk4	cyclin-dependent kinase 4	0.026
Il8rb	interleukin 8 receptor, beta	0.026	Rat
Selp	selectin P	0.025
Plscr1	phospholipid scramblase 1	0.025
Cd247	Cd247 molecule	0.025
Lyn	v-yes-1 Yamaguchi sarcoma viral related oncogene homolog	0.024
Cd68	Cd68 molecule	0.023
Cfd	complement factor D (adipsin)	0.023
Gzmk	granzyme K	0.023
Xcl1	chemokine (C motif) ligand 1	0.023	Rat
LOC685020	similar to paired immunoglobin-like type 2 receptor alpha	0.022
Tbc1d2b	TBC1 domain family, member 2B	0.022
Serpina3n	serine (or cysteine) peptidase inhibitor, clade A, member 3N	0.021
Bcl3	B-cell CLL/lymphoma 3	0.021
Il4	interleukin 4	0.021
Il1a	interleukin 1 alpha	0.021
Slpi	secretory leukocyte peptidase inhibitor	0.020
Hpgds	hematopoietic prostaglandin D synthase	0.020
Sell	selectin L	0.020
Zfp36l1	zinc finger protein 36, C3H type-like 1	0.020
LOC100361007	rCG32064-like	0.020
Tspan4	tetraspanin 4	0.020
Ncf4	neutrophil cytosolic factor 4	0.019
Adora2a	adenosine A2a receptor	0.019
Samsn1	SAM domain, SH3 domain and nuclear localization signals, 1	0.019
Socs3	suppressor of cytokine signaling 3	0.019
Ece1	endothelin converting enzyme 1	0.018
Rela	v-rel reticuloendotheliosis viral oncogene homolog A (avian)	0.018
Vamp8	vesicle-associated membrane protein 8	0.018
Rhoj	ras homolog gene family, member J	0.018
Mmp3	matrix metallopeptidase 3	0.017
Fosl1	fos-like antigen 1	0.017
Cxcl3	chemokine (C-X-C motif) ligand 3	0.016
Nfkbia	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha	0.016
Efna5	ephrin A5	0.016
Igsf7	immunoglobulin superfamily, member 7	0.016
Map3k8	mitogen-activated protein kinase kinase kinase 8	0.016
Il2rb	interleukin 2 receptor, beta	0.015
Csf1	colony stimulating factor 1 (macrophage)	0.015
Lcn2	lipocalin 2	0.015
Cebpd	CCAAT/enhancer binding protein (C/EBP), delta	0.014
Nfkb1	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1	0.014
Adrb2	adrenergic, beta-2-, receptor, surface	0.014
Atf3	activating transcription factor 3	0.014
Ch25h	cholesterol 25-hydroxylase	0.013
Cd40	CD40 molecule, TNF receptor superfamily member 5	0.013
Lilrb4	leukocyte immunoglobulin-like receptor, subfamily B, member 4	0.013
Plau	plasminogen activator, urokinase	0.013
Nfkb2	nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100	0.012
C1d	C1D nuclear receptor co-repressor	0.012
Cd8a	CD8a molecule	0.011
Rbpj	recombination signal binding protein for immunoglobulin kappa J region	0.011
Ifitm3	interferon induced transmembrane protein 3	0.011
Folr2	folate receptor 2 (fetal)	0.011
Mrc1	mannose receptor, C type 1	0.011
Gzmb	granzyme B	0.011
Ube2d2	ubiquitin-conjugating enzyme E2D 2 (UBC4/5 homolog, yeast)	0.011
Nmur2	neuromedin U receptor 2	0.010
Bcl2a1d	B-cell leukemia/lymphoma 2 related protein A1d	0.010
Ncr1	natural cytotoxicity triggering receptor 1	0.010
Snrpe	small nuclear ribonucleoprotein polypeptide E	0.010
Gch1	GTP cyclohydrolase 1	0.010
Npr3	natriuretic peptide receptor C/guanylate cyclase C (atrionatriuretic peptide receptor C)	0.010